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Cryogel scaffolds for localised delivery of lipopolysaccharide in organotypic spinal cord slice cultures: A novel ex vivo model of neuroinflammation.
Materials Today Bio
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Neurotransmitter-endcapped poly(β-amino estate) for enhanced DNA delivery to the brain through intravenous injection.
International Journal of Biological Macromolecules
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Repurposing neurological drugs for brain cancer therapeutics: A systematic approach to identify charged molecules for affinity-based local drug delivery systems.
International Journal of Pharmaceutics
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Vortioxetine: A potential drug for repurposing for glioblastoma treatment via a microsphere local delivery system.
ACS Biomaterials Science & Engineering
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Wang, Yu, Le Joncour, Vadim, Laakkonen, Pirjo and Newland, Ben ORCID: https://orcid.org/0000-0002-5214-2604
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Supersoft sponge-like cryogel as an implant to treat glioblastoma.
Neuro-Oncology
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Narasimhan, Kaushik, Hakami, Abrar, Comini, Giulia, Patton, Tommy, Newland, Ben ORCID: https://orcid.org/0000-0002-5214-2604 and Dowd, Eilís
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Cryogel microcarriers loaded with glial cell line-derived neurotrophic factor enhance the engraftment of primary dopaminergic neurons in a rat model of Parkinson’s disease.
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Cryogel microcarriers for sustained local delivery of growth factors to the brain.
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Poly(ethylene glycol)(PEG)-Cryogels: a novel platform towards enzymatic electrochemiluminescence (ECL)-based sensor applications.
Electrochimica Acta
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Injectable local drug delivery systems for glioblastoma: a systematic review and meta -analysis of progress to date †.
Biomaterials Science
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Local delivery to malignant brain tumors: potential biomaterial-based therapeutic/adjuvant strategies.
Biomaterials Science
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Does local drug delivery still hold therapeutic promise for brain cancer? A systematic review.
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Reactive oxygen species (ROS): utilizing injectable antioxidative hydrogels and ROS-producing therapies to manage the double-edged sword.
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Sulfonated cryogel scaffolds for focal delivery in ex-vivo brain tissue cultures.
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Injectable glycosaminoglycan-based cryogels from well-defined microscale templates for local growth factor delivery.
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Selective vulnerability of inhibitory networks in multiple sclerosis.
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Biomaterial based strategies to reconstruct the nigrostriatal pathway in organotypic slice co-cultures.
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Growth factor therapy for Parkinson's disease: alternative delivery systems.
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Alghamdi, Majed, Chierchini, Filippo, Eigel, Dimitri, Taplan, Christian, Miles, Thomas, Pette, Dagmar, Welzel, Petra B., Werner, Carsten, Wang, Wenxin, Neto, Catia, Gumbleton, Mark ORCID: https://orcid.org/0000-0002-7386-311X and Newland, Ben ORCID: https://orcid.org/0000-0002-5214-2604
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Poly(ethylene glycol) based nanotubes for tuneable drug delivery to glioblastoma multiforme.
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Focal drug administration via heparin-containing cryogel microcarriers reduces cancer growth and metastasis.
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The ying and yang of idebenone: Not too little, not too much - cell death in NQO1 deficient cells and the mouse retina.
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Complex polymer architectures through free-radical polymerization of multivinyl monomers.
Nature Reviews Chemistry
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Macroporous heparin-based microcarriers allow long-term 3D culture and differentiation of neural precursor cells.
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Cryogel scaffolds for regionally constrained delivery of lysophosphatidylcholine to central nervous system slice cultures: A model of focal demyelination for multiple sclerosis research.
Acta Biomaterialia
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Liu, Shuai, Gao, Yongsheng, Zhou, Dezhong, Zeng, Ming, Alshehri, Fatma, Newland, Ben ORCID: https://orcid.org/0000-0002-5214-2604, Lyu, Jing, O'Keeffe-Ahern, Jonathan, Greiser, Udo, Guo, Tianying, Zhang, Fengzhi and Wang, Wenxin
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Highly branched poly(β-amino ester) delivery of minicircle DNA for transfection of neurodegenerative disease related cells.
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Static and dynamic 3D culture of neural precursor cells on macroporous cryogel microcarriers.
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Oxygen producing microscale spheres affect cell survival in conditions of oxygen-glucose deprivation in a cell specific manner: implications for cell transplantation.
Biomaterials Science
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Extracellular matrix components HAPLN1, lumican, and collagen I cause hyaluronic acid-dependent folding of the developing human Neocortex.
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Soft and flexible poly(ethylene glycol) nanotubes for local drug delivery.
Nanoscale
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Catechol functionalized hyperbranched polymers as biomedical materials.
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Oxygen-producing gellan gum hydrogels for dual delivery of either oxygen or peroxide with doxorubicin.
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Controlled polymerization of multivinyl monomers: Formation of cyclized/knotted single-chain polymer architectures.
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Targeting delivery in Parkinson's disease.
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Preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi-walled carbon nanotubes.
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Synthesis of ROS scavenging microspheres from a dopamine containing poly(beta-amino ester) for applications for neurodegenerative disorders.
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A hyperbranched dopamine-containing PEG-based polymer for the inhibition of a-synuclein fibrillation.
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Magnetically controllable polymer nanotubes from a cyclized crosslinker for site-specific delivery of doxorubicin.
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Tackling cell transplantation anoikis: an injectable, shape memory cryogel microcarrier platform material for stem cell and neuronal cell growth.
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Prospects for polymer therapeutics in Parkinson's disease and other neurodegenerative disorders.
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Untying a nanoscale knotted polymer structure to linear chains for efficient gene delivery in vitro and to the brain.
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