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Integrated III-V semiconductor flow cytometer with capillary fill micro-fluidics

Thomas, Robert, Holton, M., Sobiesierski, Angela, Gillgrass, Sara-Jayne, Summers, H. D., Barrow, Denise and Smowton, Peter Michael ORCID: 2015. Integrated III-V semiconductor flow cytometer with capillary fill micro-fluidics. Presented at: 2015 IEEE Photonics Conference (IPC), Reston, VA, USA, 4 - 8 October 2015. IEEE Xplore. 2015 Photogenics Conference. IEEE, pp. 7-8. 10.1109/IPCon.2015.7323580

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Micro-electro-mechanical systems (MEMS) and micro-fluidic technologies offer a potential route toward truly low cost, portable/disposable flow cytometers e.g. [1]. Currently, however, dependence on external light sources, detectors and fluid pumping equipment undermines true portability and adds significant cost. Emitters and detectors can be incorporated on-chip using pick-and place style fabrication e.g. [2], but, alignment constraints and cost make this approach impractical for anything but the simplest systems. We present a prototype of an integrated III-V semiconductor flow cytometer with an on-chip capillary fill fluid delivery system designed to overcome these limitations. Monolithic integration allows photonic elements such as lasers and photo-detectors to be defined on a common substrate using high resolution lithographic techniques while use of capillary fill micro-fluidics removes the need for large scale expensive pumping equipment.

Item Type: Conference or Workshop Item (UNSPECIFIED)
Date Type: Published Online
Status: Published
Schools: Physics and Astronomy
Subjects: Q Science > QC Physics
Publisher: IEEE
ISBN: 978-1-4799-7465-8/15
ISSN: 1092-8081
Last Modified: 01 Nov 2022 10:41

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