Man, S. Y., Graham, C. A., Chan, S. S. W., Mak, P. S. K., Yu, A. H. Y., Cheung, C. S. K., Cheung, P. S. Y., Lui, G., Lee, N., Chan, M., Ip, M. and Rainer, Timothy ORCID: https://orcid.org/0000-0003-3355-3237 2011. Disease severity prediction for nursing home-acquired pneumonia in the emergency department. Emergency Medicine Journal 28 (12) , pp. 1046-1050. 10.1136/emj.2010.107235 |
Abstract
Background Prediction rules exist for the assessment of community-acquired pneumonia but their use in nursing home-acquired pneumonia (NHAP) remains undefined. The objectives of this study were to compare the prognostic ability for severe NHAP of five prediction rules (PSI, CURB-65, M-ATS, R-ATS, España rule), and to evaluate their usefulness to identify patients with less severe disease in the emergency department for outpatient care. Methods A prospective observational study of consecutive NHAP patients was conducted at a university teaching hospital emergency department in Hong Kong between January 2004 and June 2005. The primary outcome was severe pneumonia (defined as combined 30-day mortality and/or intensive care unit (ICU) admission). Results 767 consecutive NHAP patients were included. Mean (SD) age was 83.4 (9.0) years; 350 (45.6%) were male and 644 (84.0%) had coexisting illness. 95 patients died within 30 days (12.4%), five patients were admitted to the ICU (0.7%) and 98 patients had severe pneumonia (12.8%). Sensitivity and specificity of each decision rule ranged from 37.8% to 95.9% and 15.1% to 87.6% respectively. The overall predictive performance of each rule was between 0.627 and 0.712. The negative likelihood ratios of PSI (0.27) and CURB-65 (0.23) were lower than M-ATS (0.71), R-ATS (0.45) and España (0.39). After excluding 204 patients with either poor functional status or those >90 years of age, sensitivities of M-ATS (96.0%) and R-ATS (100%) improved greatly with negative likelihood ratios of <0.1. Conclusion PSI and CURB-65 are useful for identification of patients with less severe NHAP.
Item Type: | Article |
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Date Type: | Published Online |
Status: | Published |
Schools: | Medicine |
Subjects: | R Medicine > R Medicine (General) |
Publisher: | BMJ Publishing Group |
ISSN: | 1472-0205 |
Date of Acceptance: | 2 November 2010 |
Last Modified: | 01 Nov 2022 10:44 |
URI: | https://orca.cardiff.ac.uk/id/eprint/92693 |
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