Plasma DNA, prediction and post-traumatic complications

Rainer, Timothy ORCID: https://orcid.org/0000-0003-3355-3237 2001. Plasma DNA, prediction and post-traumatic complications. Clinica Chimica Acta 313 (1-2) , pp. 81-85. 10.1016/S0009-8981(01)00653-2

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Abstract

Background: Trauma is a global public health problem that claimed 5.1 million lives in 1990. Twenty percent of these deaths occurred days to weeks after injury and were due to sepsis or organ failure. Therapies to improve survival outcome after injury are limited by our inability to accurately stratify trauma patients at risk for these complications. In this review, the challenge of predicting post-traumatic complications is presented. There is potential for plasma DNA in diagnosis, prediction and monitoring non-traumatic disease. Conclusions: The mechanisms and clearance of plasma DNA have a potential role as a predictor in trauma.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General)
Publisher:	Elsevier
ISSN:	0009-8981
Last Modified:	01 Nov 2022 10:48
URI:	https://orca.cardiff.ac.uk/id/eprint/92929

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