Structure-based optimization of potent, selective, and orally bioavailable CDK8 inhibitors discovered by high-throughput screening

Czodrowski, Paul, Mallinger, Aurélie, Wienke, Dirk, Esdar, Christina, Pöschke, Oliver, Busch, Michael, Rohdich, Felix, Eccles, Suzanne A., Ortiz-Ruiz, Maria-Jesus, Schneider, Richard, Raynaud, Florence I., Clarke, Paul A., Musil, Djordje, Schwarz, Daniel, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963, Urbahns, Klaus, Blagg, Julian and Schiemann, Kai 2016. Structure-based optimization of potent, selective, and orally bioavailable CDK8 inhibitors discovered by high-throughput screening. Journal of Medicinal Chemistry 59 (20) , pp. 9337-9349. 10.1021/acs.jmedchem.6b00597

Preview

PDF - Published Version Available under License Creative Commons Attribution No Derivatives. Download (8MB) | Preview

Item Type:	Article
Date Type:	Published Online
Status:	Published
Schools:	Schools > Biosciences Research Institutes & Centres > European Cancer Stem Cell Research Institute (ECSCRI)
ISSN:	0022-2623
Date of First Compliant Deposit:	9 December 2016
Date of Acceptance:	4 August 2016
Last Modified:	01 Jul 2023 13:57
URI:	https://orca.cardiff.ac.uk/id/eprint/96681

Citation Data

Cited 65 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item