Insertion and deletion of exons during human gene evolution

Cooper, David Neil ORCID: https://orcid.org/0000-0002-8943-8484 2007. Insertion and deletion of exons during human gene evolution. eLS, Wiley-Blackwell, (10.1002/9780470015902.a0005088.pub2)

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Abstract

During the evolution of human genes, exons have been both acquired and lost. The study of the structure of orthologous mammalian genes provides numerous examples of the gain or loss of exons by a variety of different mechanisms.

Item Type:	Book Section
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	Q Science > QH Natural history > QH426 Genetics
Uncontrolled Keywords:	exon deletion; exon insertion; exon duplication/amplification; exon shuffling; LINE element-mediated recombination; alternative splicing; pseudoexons
Publisher:	Wiley-Blackwell
Last Modified:	02 Nov 2022 09:59
URI:	https://orca.cardiff.ac.uk/id/eprint/97072

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