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Aryloxy pivaloyloxymethyl prodrugs as nucleoside monophosphate prodrugs.
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10.1021/acs.jmedchem.1c01490
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Miccoli, Ageo, Dhiani, Binar A., Thornton, Peter J., Lambourne, Olivia A., James, Edward, Kadri, Hachemi and Mehellou, Youcef ORCID: https://orcid.org/0000-0001-5720-8513
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Aryloxy triester phosphoramidates as phosphoserine prodrugs: a proof of concept study.
ChemMedChem
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Miccoli, Ageo
2019.
Development of novel phospho-amino acid prodrugs as powerful tools in drug discovery.
PhD Thesis,
Cardiff University.
Item availability restricted. |
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Miccoli, Ageo, Dhiani, Binar and Mehellou, Youcef ORCID: https://orcid.org/0000-0001-5720-8513
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Phosphotyrosine prodrugs: design, synthesis and anti-STAT3 activity of ISS-610 aryloxy triester phosphoramidate prodrugs.
MedChemComm
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Barini, Erica, Miccoli, Ageo, Tinarelli, Federico, Mulholand, Katie, Kadri, Hachemi, Khanim, Farhat, Stojanovski, Laste, Read, Kevin D, Burness, Kerry, Blow, Julian J, Mehellou, Youcef ORCID: https://orcid.org/0000-0001-5720-8513 and Muqit, Miratul
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The anthelmintic drug niclosamide and its analogues activate the Parkinson's Disease associated protein kinase PINK1.
Chembiochem
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Osgerby, Laura, Lai, Yu-Chiang, Thornton, Peter J., Amalfitano, Joseph, Le Duff, Cécile S., Jabeen, Iqra, Kadri, Hachemi, Miccoli, Ageo, Tucker, James H. R., Muqit, Miratul M. K. and Mehellou, Youcef ORCID: https://orcid.org/0000-0001-5720-8513
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Kinetin riboside and its ProTides activate the Parkinson's Disease associated PTEN-Induced Putative Kinase 1 (PINK1) independent of mitochondrial depolarization.
Journal of Medicinal Chemistry
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10.1021/acs.jmedchem.6b01897
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Thornton, Peter J., Kadri, Hachemi, Miccoli, Ageo and Mehellou, Youcef ORCID: https://orcid.org/0000-0001-5720-8513
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Nucleoside phosphate and phosphonate prodrug clinical candidates.
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