Yevglevskis, Maksims, Nathubhai, Amit, Wadda, Katty, Lee, Guat L., Al-Rawi, Suzanne, Jiao, Tingying, Mitchell, Paul J., James, Tony D., Threadgill, Michael D., Woodman, Timothy J. and Lloyd, Matthew D. 2019. Novel 2-arylthiopropanoyl-CoA inhibitors of α-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents. Bioorganic Chemistry 92 , 103263. 10.1016/j.bioorg.2019.103263 |
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Petrova, Yoana D., Wadda, Katty, Nathubhai, Amit, Jevglevskis, Maksims, Mitchell, Paul J., James, Tony D., Threadgill, Michael D., Woodman, Timothy J. and Lloyd, Matthew D. 2019. Identification of novel small-molecule inhibitors of α-methylacyl-CoA (AMACR; P504S) and structure-activity relationships. Bioorganic Chemistry 92 , 103264. 10.1016/j.bioorg.2019.103264 |
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Yevglevskis, Maksims, Lee, Guat L., Nathubhai, Amit, Petrova, Yoana D., James, Tony D., Threadgill, Michael D., Woodman, Timothy J. and Lloyd, Matthew D.
2018.
Structure-activity relationships of rationally designed AMACR 1A inhibitors.
Bioorganic Chemistry
79
, pp. 145-154.
10.1016/j.bioorg.2018.04.024
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Sedgwick, Adam C., Gardiner, Jordan E., Kim, Gyoungmi, Yevglevskis, Maksims, Lloyd, Matthew D., Jenkins, A. Toby A., Bull, Steven D., Yoon, Juyoung and James, Tony D.
2018.
Long-wavelength TCF-based fluorescence probes for the detection and intracellular imaging of biological thiols.
Chemical Communications
54
(38)
, pp. 4786-4789.
10.1039/C8CC01661E
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Yevglevskis, Maksims, Lee, Guat L., Nathubhai, Amit, Petrova, Yoana D., James, Tony D., Threadgill, Michael D., Woodman, Timothy J. and Lloyd, Matthew D.
2017.
A novel colorimetric assay for α-methylacyl-CoA racemase 1A (AMACR; P504S) utilizing the elimination of 2,4-dinitrophenolate.
Chemical Communications
53
(37)
, pp. 5087-5090.
10.1039/C7CC00476A
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Yevglevskis, Maksims, Lee, Guat L., Sun, Jenny, Zhou, Shiyi, Sun, Xiaolong, Kociok-Köhn, Gabriele, James, Tony D., Woodman, Timothy J. and Lloyd, Matthew D.
2016.
A study on the AMACR catalysed elimination reaction and its application to inhibitor testing.
Organic and Biomolecular Chemistry
14
(2)
, pp. 612-622.
10.1039/C5OB01541C
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Yevglevskis, Maksims, Lee, Guat L., Threadgill, Michael D., Woodman, Timothy J. and Lloyd, Matthew D. 2014. The perils of rational design – unexpected irreversible elimination of fluoride from 3-fluoro-2-methylacyl-CoA esters catalysed by α-methylacyl-CoA racemase (AMACR; P504S). Chemical Communications 50 (91) , pp. 14164-14166. 10.1039/C4CC06127F |
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Yevglevskis, Maksims, Bowskill, Catherine R., Chan, Chloe C. Y., Heng, Justin H.-J., Threadgill, Michael D., Woodman, Timothy J. and Lloyd, Matthew D. 2014. A study on the chiral inversion of mandelic acid in humans. Organic and Biomolecular Chemistry 12 (34) 10.1039/C3OB42515K |
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Lloyd, Matthew D., Yevglevskis, Maksims, Lee, Guat Ling, Wood, Pauline J., Threadgill, Michael D. and Woodman, Timothy J. 2013. α-Methylacyl-CoA racemase (AMACR): Metabolic enzyme, drug metabolizer and cancer marker P504S. Progress in Lipid Research 52 (2) , pp. 220-230. 10.1016/j.plipres.2013.01.001 |
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Uosis-Martin, Mario, Mahon, Mary, Yevglevskis, Maksims and Lewis, Simon 2011. Concise synthesis of 1,4a-bifunctionalised decalin building blocks by C-H activation of decalin. SYNLETT 2011 (15) , pp. 2211-2213. 10.1055/s-0030-1261184 |
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