Dual role for phenylalanine 178 during catalysis by aristolochene synthase

Forcat, Silvia and Allemann, Rudolf Konrad ORCID: https://orcid.org/0000-0002-1323-8830 2004. Dual role for phenylalanine 178 during catalysis by aristolochene synthase. Chemical Communications (18) , pp. 2094-2095. 10.1039/b407932a

Full text not available from this repository.

Abstract

A mutant of aristolochene synthase, in which Phe 178 was replaced by Val, produced significant amounts of α- and β-farnesene as well as α and β-selinene and selina-4,11-diene, suggesting that Phe 178 is involved in the stabilisation of transition states preceding germacrene A and following eudesmane cation.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Chemistry Cardiff Catalysis Institute (CCI)
Subjects:	Q Science > QD Chemistry
Publisher:	RSC Publishing
ISSN:	1359-7345
Last Modified:	18 Oct 2022 13:19
URI:	https://orca.cardiff.ac.uk/id/eprint/13486

Citation Data

Cited 25 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item