Plexin-B1 mutation drives metastasis in prostate cancer mouse models

Shorning, Boris, Trent, Neil, Griffiths, David F., Worzfeld, Thomas, Offermanns, Stefan, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 and Williamson, Magali 2023. Plexin-B1 mutation drives metastasis in prostate cancer mouse models. Cancer Research Communications 3 (3) , pp. 444-458. 10.1158/2767-9764.CRC-22-0480

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Abstract

Metastatic prostate cancer is essentially incurable and is a leading cause of cancer-related morbidity and mortality in men, yet the underlying molecular mechanisms are poorly understood. Plexins are transmembrane receptors for semaphorins with divergent roles in many forms of cancer.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine Biosciences European Cancer Stem Cell Research Institute (ECSCRI)
Publisher:	American Association for Cancer Research
ISSN:	2767-9764
Date of First Compliant Deposit:	12 January 2023
Date of Acceptance:	10 February 2023
Last Modified:	17 May 2023 01:00
URI:	https://orca.cardiff.ac.uk/id/eprint/155803

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