Morgan, Huw J., Olivero, Carlotta ORCID: https://orcid.org/0000-0002-8961-6703, Shorning, Boris Y., Gibbs, Alex, Phillips, Alexandra L., Ananthan, Lokapriya, Lim, Annabelle Xiao Hui, Martuscelli, Licia, Borgogna, Cinzia, De Andrea, Marco, Hufbauer, Martin, Goodwin, Richard G., Akgül, Baki, Gariglio, Marisa and Patel, Girish K. 2024. HPV8-induced STAT3 activation led keratinocyte stem cell expansion in human actinic keratoses. JCI Insight 9 (15) , e177898. 10.1172/jci.insight.177898 |
Shorning, Boris, Trent, Neil, Griffiths, David F., Worzfeld, Thomas, Offermanns, Stefan, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 and Williamson, Magali 2023. Plexin-B1 mutation drives metastasis in prostate cancer mouse models. Cancer Research Communications 3 (3) , pp. 444-458. 10.1158/2767-9764.CRC-22-0480 |
Morgan, Huw J., Rees, Elise, Lanfredini, Simone ORCID: https://orcid.org/0000-0002-3160-5120, Powell, Kate A., Gore, Jasmine, Gibbs, Alex, Lovatt, Charlotte, Davies, Gemma E., Olivero, Carlotta ORCID: https://orcid.org/0000-0002-8961-6703, Shorning, Boris Y., Tornillo, Giusy, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Darley, Richard ORCID: https://orcid.org/0000-0003-0879-0724, Wang, Eddie C.Y. ORCID: https://orcid.org/0000-0002-2243-4964 and Patel, Girish K. 2022. CD200 ectodomain shedding into the tumor microenvironment leads to NK cell dysfunction and apoptosis. Journal of Clinical Investigation 132 (21) , e150750. 10.1172/JCI150750 |
Shorning, Boris Y., Dass, Manisha S., Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 and Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843 2020. The PI3K-AKT-mTOR pathway and prostate cancer: at the crossroads of AR, MAPK, and WNT signaling. International Journal of Molecular Sciences 21 (12) , 4507. 10.3390/ijms21124507 |
Jefferies, Matthew T., Cox, Adam C., Shorning, Boris Y., Meniel, Valerie, Griffiths, David, Kynaston, Howard G. ORCID: https://orcid.org/0000-0003-1902-9930, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 and Clarke, Alan R. 2017. PTEN loss and activation of K-RAS and β-catenin cooperate to accelerate prostate tumourigenesis. Journal of Pathology 243 (4) , pp. 442-456. 10.1002/path.4977 |
Shorning, Boris and Clarke, Alan R. 2016. Energy sensing and cancer: LKB1 function and lessons learnt from Peutz-Jeghers syndrome. Seminars in Cell and Developmental Biology 52 , pp. 21-29. 10.1016/j.semcdb.2016.02.015 |
Holik, Aliaksei Z., Young, Madeleine, Krzystyniak, Joanna, Williams, Geraint T. ORCID: https://orcid.org/0000-0003-3768-9940, Metzger, Daniel, Shorning, Boris Y. and Clarke, Alan R. ORCID: https://orcid.org/0000-0002-4281-426X 2014. Brg1 loss attenuates aberrant Wnt-signalling and prevents Wnt-dependent tumourigenesis in the murine small intestine. PLoS Genetics 10 (7) , e1004453. 10.1371/journal.pgen.1004453 |
Holik, Aliaksei, Krzystyniak, Joanna, Young, Madeleine, Richardson, Kirsty, Jarde, Thierry, Chambon, Pierre, Shorning, Boris and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2013. Brg1 is required for stem cell maintenance in the murine intestinal epithelium in a tissue-specific manner. Stem Cells 31 (11) , pp. 2457-2466. 10.1002/stem.1498 |
Khritankova, I. V., Kukharskiy, M. S., Lytkina, O. A., Bachurin, S. O. and Shorning, Boris 2012. Dimebon activates autophagosome components in human neuroblastoma SH-SY5Y cells. Doklady Biochemistry and Biophysics 446 (1) , pp. 251-253. 10.1134/S1607672912050079 |
Williams, Rebecca ORCID: https://orcid.org/0000-0003-2168-7369, Shorning, Boris, Datta, S., Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2012. Development and characterisation of a bladder cancer model [Poster]. BJU International 109 (S7) , p. 25. 10.1111/j.1464-410X.2012.11177.x |
Shorning, Boris, Jarde, Thierry, McCarthy, Afshan, Ashworth, Alan, de Leng, Wendy W. J., Offerhaus, George Johan A., Resta, Nicoletta, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2012. Intestinal renin-angiotensin system is stimulated after deletion of Lkb1. Gut 61 (2) , pp. 202-213. 10.1136/gutjnl-2011-300046 |
Shorning, Boris and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2011. LKB1 loss of function studied in vivo. FEBS Letters 585 (7) , pp. 958-966. 10.1016/j.febslet.2011.01.019 |
Shorning, Boris, Griffiths, David Francis Rees and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2011. Lkb1 and Pten synergise to suppress mTOR-mediated tumorigenesis and epithelial-mesenchymal transition in the mouse bladder. PLoS ONE 6 (1) , e16209. 10.1371/journal.pone.0016209 |
Ruzov, Alexey, Shorning, Boris, Mortusewicz, Oliver, Dunican, Donncha S., Leonhardt, Heinrich and Meehan, Richard R. 2009. MBD4 and MLH1 are required for apoptotic induction in xDNMT1-depleted embryos. Development 136 (13) , pp. 2277-2286. 10.1242/dev.032227 |
Shorning, Boris, Zabkiewicz, Joanna ORCID: https://orcid.org/0000-0003-0951-3825, McCarthy, Afshan, Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, Winton, Douglas J., Sansom, Owen J., Ashworth, Alam and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2009. Lkb1 deficiency alters goblet and paneth cell differentiation in the small intestine. PLoS ONE 4 (1) , e4264. 10.1371/journal.pone.0004264 |