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MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate antimicrobial function: Defining a novel mechanism of superantigen-induced immunopathology and immunosuppression

Shaler, Christopher R., Choi, Joshua, Rudak, Patrick T., Memarnejadian, Arash, Szabo, Peter A., Tun-Abraham, Mauro E., Rossjohn, Jamie

, Corbett, Alexandra J., McCluskey, James, McCormick, John K., Lantz, Olivier, Hernandez-Alejandro, Roberto and Haeryfar, S.M. Mansour 2017. MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate antimicrobial function: Defining a novel mechanism of superantigen-induced immunopathology and immunosuppression. PLoS Biology 15 (6) , e2001930. 10.1371/journal.pbio.2001930

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Official URL: http://dx.doi.org/10.1371/journal.pbio.2001930

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	Q Science > QR Microbiology > QR180 Immunology
Publisher:	Public Library of Science
ISSN:	1545-7885
Date of First Compliant Deposit:	5 July 2017
Date of Acceptance:	11 May 2017
Last Modified:	04 May 2023 05:23
URI:	https://orca.cardiff.ac.uk/id/eprint/102070

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Cited 83 times in Scopus. View in Scopus. Powered By Scopus® Data

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