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Number of items: 249.

Awad, Wael, Mayall, Jemma R., Xu, Weijun, Johansen, Matt D., Patton, Timothy, Lim, Xin Yi, Galvao, Izabela, Howson, Lauren J., Brown, Alexandra C., Haw, Tatt Jhong, Donovan, Chantal, Das, Shatarupa, Albers, Gesa J., Pai, Tsung-Yu, Hortle, Elinor, Gillis, Caitlin M., Hansbro, Nicole G., Horvat, Jay C., Liu, Ligong, Mak, Jeffrey Y. W., McCluskey, James, Fairlie, David P., Corbett, Alexandra J., Hansbro, Philip M. and Rossjohn, Jamie

2025. Cigarette smoke components modulate the MR1-MAIT axis. Journal of Experimental Medicine 222 (2) , e20240896. 10.1084/jem.20240896

Petersen, Jan, Llerena, Carmen, Golzarroshan, Bagher, Faoro, Camilla, Triebel, Frederic and Rossjohn, Jamie

2024. Crystal structure of the human LAG-3–HLA-DR1–peptide complex. Science Immunology 9 (102) , eads5122. 10.1126/sciimmunol.ads5122

McMaster, Benjamin, Thorpe, Christopher J., Rossjohn, Jamie

, Deane, Charlotte M. and Koohy, Hashem 2024. Quantifying conformational changes in the TCR:pMHC-I binding interface. Frontiers in Immunology 15 , 1491656. 10.3389/fimmu.2024.1491656

Loh, Liyen, Saunders, Philippa M., Faoro, Camilla, Font-Porterias, Neus, Nemat-Gorgani, Neda, Harrison, Genelle F., Sadeeq, Suraju, Hensen, Luca, Wong, Shu Cheng, Widjaja, Jacqueline, Clemens, E. Bridie, Zhu, Shiying, Kichula, Katherine M., Tao, Sudan, Zhu, Faming, Montero-Martin, Gonzalo, Fernandez-Vina, Marcelo, Guethlein, Lisbeth A., Vivian, Julian P., Davies, Jane, Mentzer, Alexander J., Oppenheimer, Stephen J., Pomat, William, Ioannidis, Alexander G., Barberena-Jonas, Carmina, Moreno-Estrada, Andrés, Miller, Adrian, Parham, Peter, Rossjohn, Jamie

, Tong, Steven Y.C., Kedzierska, Katherine, Brooks, Andrew G. and Norman, Paul J. 2024. An archaic HLA class I receptor allele diversifies natural killer cell-driven immunity in First Nations peoples of Oceania. Cell 187 (24) , pp. 7008-7024. 10.1016/j.cell.2024.10.005

McInerney, Mitchell P., Awad, Wael, Souter, Michael N. T., Kang, Yang, Wang, Carl J. H., Chan Yew Poa, Kean, Abdelaal, Mohamed R., Le, Ngoc H., Shepherd, Chloe M., McNeice, Conor, Meehan, Lucy J., Nelson, Adam G., Raynes, Jeremy M., Mak, Jeffrey Y. W., McCluskey, James, Chen, Zhenjun, Ang, Ching-Seng, Fairlie, David P., Le Nours, Jérôme, Illing, Patricia T., Rossjohn, Jamie

and Purcell, Anthony W. 2024. MR1 presents vitamin B6–related compounds for recognition by MR1-reactive T cells. Proceedings of the National Academy of Sciences 121 (49) , e2414792121. 10.1073/pnas.2414792121

Samer, Carolyn, McWilliam, Hamish E.G., McSharry, Brian P., Burchfield, James G., Stanton, Richard J.

, Rossjohn, Jamie

, Villadangos, Jose A., Abendroth, Allison and Slobedman, Barry 2024. Impaired endocytosis and accumulation in early endosomal compartments defines herpes simplex virus–mediated disruption of the nonclassical MHC class I–related molecule MR1. Journal of Biological Chemistry 300 (10) , 107748. 10.1016/j.jbc.2024.107748

Gully, Benjamin S., Ferreira Fernandes, João, Gunasinghe, Sachith D., Vuong, Mai T., Lui, Yuan, Rice, Michael T., Rashleigh, Liam, Lay, Chan-sien, Littler, Dene R., Sharma, Sumana, Santos, Ana Mafalda, Venugopal, Hariprasad, Rossjohn, Jamie

and Davis, Simon J. 2024. Structure of a fully assembled γδ T cell antigen receptor. Nature 634 (8034) , pp. 729-736. 10.1038/s41586-024-07920-0

Almeida, Catarina F., Gully, Benjamin S., Jones, Claerwen M., Kedzierski, Lukasz, Gunasinghe, Sachith D., Rice, Michael T., Berry, Richard, Gherardin, Nicholas A., Nguyen, Trang T., Mok, Yee-Foong, Reijneveld, Josephine F., Moody, D. Branch, Van Rhijn, Ildiko, La Gruta, Nicole L., Uldrich, Adam P., Rossjohn, Jamie

and Godfrey, Dale I. 2024. Direct recognition of an intact foreign protein by an αβ T cell receptor. Nature Communications 15 , 8816. 10.1038/s41467-024-51897-3

Hayday, Adrian, Dechanet-Merville, Julie, Rossjohn, Jamie

and Silva-Santos, Bruno 2024. Cancer immunotherapy by γδ T cells. Science 386 (6717) , eabq7248. 10.1126/science.abq7248

Cornforth, Terri V., Moyo, Nathifa, Cole, Suzanne, Lam, Emily P. S., Lobry, Tatiana, Wolchinsky, Ron, Lloyd, Angharad, Ward, Katarzyna, Denham, Eleanor M., Masi, Giulia, Qing Yun, Phyllis Tea, Moore, Colin, Dhaouadi, Selsabil, Besra, Gurdyal S., Veerapen, Natacha, Illing, Patricia T., Vivian, Julian P., Raynes, Jeremy M., Le Nours, Jérôme, Purcell, Anthony W., Kundu, Samit, Silk, Jonathan D., Williams, Luke, Papa, Sophie, Rossjohn, Jamie

, Howie, Duncan and Dukes, Joseph 2024. Conserved allomorphs of MR1 drive the specificity of MR1-restricted TCRs. Frontiers in Oncology 14 , 1419528. 10.3389/fonc.2024.1419528

Rowntree, Louise C., Audsley, Jennifer, Allen, Lilith F., McQuilten, Hayley A., Hagen, Ruth R., Chaurasia, Priyanka, Petersen, Jan, Littler, Dene R., Tan, Hyon-Xhi, Murdiyarso, Lydia, Habel, Jennifer R., Foo, Isabelle J. H., Zhang, Wuji, ten Berge, Elizabeth R. V., Ganesh, Hanujah, Kaewpreedee, Prathanporn, Lee, Kelly W. K., Cheng, Samuel M. S., Kwok, Janette S. Y., Jayasinghe, Dhilshan, Gras, Stephanie, Juno, Jennifer A., Wheatley, Adam K., Kent, Stephen J., Rossjohn, Jamie

, Cheng, Allen C., Kotsimbos, Tom C., Trubiano, Jason A., Holmes, Natasha E., Pang Chan, Ken Ka, Hui, David S. C., Peiris, Malik, Poon, Leo L. M., Lewin, Sharon R., Doherty, Peter C., Thevarajan, Irani, Valkenburg, Sophie A., Kedzierska, Katherine and Nguyen, Thi H. O. 2024. SARS-CoV-2-specific CD8+ T cells from people with long COVID establish and maintain effector phenotype and key TCR signatures over 2 years. Proceedings of the National Academy of Sciences 121 (39) , e2411428121. 10.1073/pnas.2411428121

Pymm, Phillip, Saunders, Philippa M., Anand, Sushma, MacLachlan, Bruce J., Faoro, Camilla, Hitchen, Corinne, Rossjohn, Jamie

, Brooks, Andrew G. and Vivian, Julian P. 2024. The structural basis for recognition of human leukocyte antigen class I molecules by the Pan-HLA antibody w6/32. The Journal of Immunology 213 (6) , pp. 876-885. 10.4049/jimmunol.2400328

Sok, Chhon Ling, Rossjohn, Jamie

and Gully, Benjamin S. 2024. The evolving portrait of γδ TCR recognition determinants. The Journal of Immunology 213 (5) , pp. 543-552. 10.4049/jimmunol.2400114

Cao, Thinh-Phat, Shahine, Adam, Cox, Liam R., Besra, Gurdyal S., Moody, D. Branch and Rossjohn, Jamie

2024. A structural perspective of how T cell receptors recognize the CD1 family of lipid antigen-presenting molecules. Journal of Biological Chemistry 300 (8) , 107511. 10.1016/j.jbc.2024.107511

Braun, Asolina, Rowntree, Louise C., Huang, Ziyi, Pandey, Kirti, Thuesen, Nikolas, Li, Chen, Petersen, Jan, Littler, Dene R., Raji, Shabana, Nguyen, Thi H. O., Jappe Lange, Emma, Persson, Gry, Schantz Klausen, Michael, Kringelum, Jens, Chung, Shanzou, Croft, Nathan P., Faridi, Pouya, Ayala, Rochelle, Rossjohn, Jamie

, Illing, Patricia T., Scull, Katherine E., Ramarathinam, Sri, Mifsud, Nicole A., Kedzierska, Katherine, Sørensen, Anders Bundgård and Purcell, Anthony W. 2024. Mapping the immunopeptidome of seven SARS-CoV-2 antigens across common HLA haplotypes. Nature Communications 15 (1) , 7547. 10.1038/s41467-024-51959-6

Jia, Xiaoxiao, Crawford, Jeremy Chase, Gebregzabher, Deborah, Monson, Ebony A., Mettelman, Robert C., Wan, Yanmin, Ren, Yanqin, Chou, Janet, Novak, Tanya, McQuilten, Hayley A., Clarke, Michele, Bachem, Annabell, Foo, Isabelle J., Fritzlar, Svenja, Carrera Montoya, Julio, Trenerry, Alice M., Nie, Shuai, Leeming, Michael G., Nguyen, Thi H.O., Kedzierski, Lukasz, Littler, Dene R., Kueh, Andrew, Cardamone, Tina, Wong, Chinn Yi, Hensen, Luca, Cabug, Aira, Laguna, Jaime Gómez, Agrawal, Mona, Flerlage, Tim, Boyd, David F., Van de Velde, Lee-Ann, Habel, Jennifer R., Loh, Liyen, Koay, Hui-Fern, van de Sandt, Carolien E., Konstantinov, Igor E., Berzins, Stuart P., Flanagan, Katie L., Wakim, Linda M., Herold, Marco J., Green, Amanda M., Smallwood, Heather S., Rossjohn, Jamie

, Thwaites, Ryan S., Chiu, Christopher, Scott, Nichollas E., Mackenzie, Jason M., Bedoui, Sammy, Reading, Patrick C., Londrigan, Sarah L., Helbig, Karla J., Randolph, Adrienne G., Thomas, Paul G., Xu, Jianqing, Wang, Zhongfang, Chua, Brendon Y. and Kedzierska, Katherine 2024. High expression of oleoyl-ACP hydrolase underpins life-threatening respiratory viral diseases. Cell 187 (17) , pp. 4586-4604. 10.1016/j.cell.2024.07.026

Loh, Tiing Jen, Lim, Jia Jia, Jones, Claerwen M., Dao, Hien Thy, Tran, Mai T., Baker, Daniel G., La Gruta, Nicole L., Reid, Hugh H. and Rossjohn, Jamie

2024. The molecular basis underlying T cell specificity towards citrullinated epitopes presented by HLA-DR4. Nature Communications 15 (1) , 6201. 10.1038/s41467-024-50511-w

Tandori, Erica, Ciacchi, Laura, Ciacchi, Lisa, Ly‐Huynh, Jennifer D., Favilla, Stuart and Rossjohn, Jamie

2024. Access all areas: multisensory science exhibitions tailored toward blind, low‐vision and diverse‐needs communities. Immunology & Cell Biology 102 (5) , pp. 321-325. 10.1111/imcb.12738

MacLachlan, Bruce J., Sullivan, Lucy C., Brooks, Andrew G., Rossjohn, Jamie

and Vivian, Julian P. 2024. Structure of the murine CD94–NKG2A receptor in complex with Qa-1b presenting an MHC-I leader peptide. The FEBS Journal 291 (7) , pp. 1530-1544. 10.1111/febs.17050

Menon, Tejas, Illing, Patricia T., Chaurasia, Priyanka, McQuilten, Hayley A., Shepherd, Chloe, Rowntree, Louise C., Petersen, Jan, Littler, Dene R., Khuu, Grace, Huang, Ziyi, Allen, Lilith F., Rockman, Steve, Crowe, Jane, Flanagan, Katie L., Wakim, Linda M., Nguyen, Thi H. O., Mifsud, Nicole A., Rossjohn, Jamie

, Purcell, Anthony W., van de Sandt, Carolien E. and Kedzierska, Katherine 2024. CD8 + T-cell responses towards conserved influenza B virus epitopes across anatomical sites and age. Nature Communications 15 , 3387. 10.1038/s41467-024-47576-y

Zimmermann, Cosima, Watson, Gabrielle M., Bauersfeld, Liane, Berry, Richard, Ciblis, Barbara, Lan, Huan, Gerke, Carolin, Oberhardt, Valerie, Fuchs, Jonas, Hofmann, Maike, Freund, Christian, Rossjohn, Jamie

, Momburg, Frank, Hengel, Hartmut and Halenius, Anne 2024. Diverse cytomegalovirus US11 antagonism and MHC-A evasion strategies reveal a tit-for-tat coevolutionary arms race in hominids. Proceedings of the National Academy of Sciences 121 (9) , e2315985121. 10.1073/pnas.2315985121

Samer, Carolyn, McWilliam, Hamish E.G., McSharry, Brian P., Velusamy, Thilaga, Burchfield, James G., Stanton, Richard J.

, Tscharke, David C., Rossjohn, Jamie

, Villadangos, Jose A., Abendroth, Allison and Slobedman, Barry 2024. Multi-targeted loss of the antigen presentation molecule MR1 during HSV-1 and HSV-2 infection. iScience 27 (2) , 108801. 10.1016/j.isci.2024.108801

Zhang, Wuji, Clemens, E Bridie, Kedzierski, Lukasz, Chua, Brendon Y., Mayo, Mark, Lonzi, Claire, Hinchcliff, Alexandra, Rigas, Vanessa, Middleton, Bianca F., Binks, Paula, Rowntree, Louise C., Allen, Lilith F., Tan, Hyon‐Xhi, Petersen, Jan, Chaurasia, Priyanka, Krammer, Florian, Wheatley, Adam K., Kent, Stephen J., Rossjohn, Jamie

, Miller, Adrian, Lynar, Sarah, Nelson, Jane, Nguyen, Thi H.O., Davies, Jane and Kedzierska, Katherine 2023. Broad spectrum SARS‐CoV ‐2‐specific immunity in hospitalized First Nations peoples recovering from COVID ‐19. Immunology & Cell Biology 101 (10) , pp. 964-974. 10.1111/imcb.12691

Lameris, Roeland, Shahine, Adam, Veth, Myrthe, Westerman, Bart, Godfrey, Dale I., Lutje Hulsik, David, Brouwer, Patricia, Rossjohn, Jamie

, de Gruijl, Tanja D. and van der Vliet, Hans J. 2023. Enhanced CD1d phosphatidylserine presentation using a single-domain antibody promotes immunomodulatory CD1d-TIM-3 interactions. Journal for ImmunoTherapy of Cancer 11 , e007631. 10.1136/jitc-2023-007631

van de Sandt, Carolien E., Nguyen, Thi H. O., Gherardin, Nicholas A., Crawford, Jeremy Chase, Samir, Jerome, Minervina, Anastasia A., Pogorelyy, Mikhail V., Rizzetto, Simone, Szeto, Christopher, Kaur, Jasveen, Ranson, Nicole, Sonda, Sabrina, Harper, Alice, Redmond, Samuel J., McQuilten, Hayley A., Menon, Tejas, Sant, Sneha, Jia, Xiaoxiao, Pedrina, Kate, Karapanagiotidis, Theo, Cain, Natalie, Nicholson, Suellen, Chen, Zhenjun, Lim, Ratana, Clemens, E. Bridie, Eltahla, Auda, La Gruta, Nicole L., Crowe, Jane, Lappas, Martha, Rossjohn, Jamie

, Godfrey, Dale I., Thomas, Paul G., Gras, Stephanie, Flanagan, Katie L., Luciani, Fabio and Kedzierska, Katherine 2023. Newborn and child-like molecular signatures in older adults stem from TCR shifts across human lifespan. Nature Immunology 24 , 1890–1907. 10.1038/s41590-023-01633-8

Huang, Shouxiong, Shahine, Adam, Cheng, Tan-Yun, Chen, Yi-Ling, Ng, Soo Weei, Balaji, Gautham R., Farquhar, Rachel, Gras, Stephanie, Hardman, Clare S., Altman, John D., Tahiri, Nabil, Minnaard, Adriaan J., Ogg, Graham S., Mayfield, Jacob A., Rossjohn, Jamie

and Moody, D. Branch 2023. CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms. Cell 186 (21) , pp. 4583-4596. 10.1016/j.cell.2023.08.022

Shahine, Adam, Van Rhijn, Ildiko, Rossjohn, Jamie

and Moody, D. Branch 2023. CD1 displays its own negative regulators. Current Opinion in Immunology 83 , 102339. 10.1016/j.coi.2023.102339

Zhao, Yu, He, Bing, Xu, Fan, Li, Chen, Xu, Zhimeng, Su, Xiaona, He, Haohuai, Huang, Yueshan, Rossjohn, Jamie

, Song, Jiangning and Yao, Jianhua 2023. DeepAIR: A deep learning framework for effective integration of sequence and 3D structure to enable adaptive immune receptor analysis. Science Advances 9 (32) 10.1126/sciadv.abo5128

Anand, Sushma, Littler, Dene R., Mobbs, Jesse I., Braun, Asolina, Baker, Daniel G., Tennant, Luke, Purcell, Anthony W., Vivian, Julian P. and Rossjohn, Jamie

2023. Complimentary electrostatics dominate T-cell receptor binding to a psoriasis-associated peptide antigen presented by human leukocyte antigen C∗06:02. Journal of Biological Chemistry 299 (7) , 104930. 10.1016/j.jbc.2023.104930

Mifsud, Nicole A., Illing, Patricia T., Ho, Rebecca, Tuomisto, Johanna E., Fettke, Heidi, Mullan, Kerry A., McCluskey, James, Rossjohn, Jamie

, Vivian, Julian, Reantragoon, Rangsima and Purcell, Anthony W. 2023. The allopurinol metabolite, oxypurinol, drives oligoclonal expansions of drug‐reactive T cells in resolved hypersensitivity cases and drug‐naïve healthy donors. Allergy 10.1111/all.15814

Zhang, Wuji, Kedzierski, Lukasz, Chua, Brendon Y., Mayo, Mark, Lonzi, Claire, Rigas, Vanessa, Middleton, Bianca F., McQuilten, Hayley A., Rowntree, Louise C., Allen, Lilith F., Purcell, Ruth A., Tan, Hyon-Xhi, Petersen, Jan, Chaurasia, Priyanka, Mordant, Francesca, Pogorelyy, Mikhail V., Minervina, Anastasia A., Crawford, Jeremy Chase, Perkins, Griffith B., Zhang, Eva, Gras, Stephanie, Clemens, E. Bridie, Juno, Jennifer A., Audsley, Jennifer, Khoury, David S., Holmes, Natasha E., Thevarajan, Irani, Subbarao, Kanta, Krammer, Florian, Cheng, Allen C., Davenport, Miles P., Grubor-Bauk, Branka, Coates, P. Toby, Christensen, Britt, Thomas, Paul G., Wheatley, Adam K., Kent, Stephen J., Rossjohn, Jamie

, Chung, Amy W., Boffa, John, Miller, Adrian, Lynar, Sarah, Nelson, Jane, Nguyen, Thi H. O., Davies, Jane and Kedzierska, Katherine 2023. Robust and prototypical immune responses toward COVID-19 vaccine in First Nations peoples are impacted by comorbidities. Nature Immunology 24 (6) , pp. 966-978. 10.1038/s41590-023-01508-y

Ciacchi, Lisa, van de Garde, Martijn D.B., Ladell, Kristin

, Farenc, Carine, Poelen, Martien C.M., Miners, Kelly L., Llerena, Carmen, Reid, Hugh H., Petersen, Jan, Price, David A.

, Rossjohn, Jamie

and van Els, Cécile A.C.M. 2023. CD4+ T cell-mediated recognition of a conserved cholesterol-dependent cytolysin epitope generates broad antibacterial immunity. Immunity 56 (5) , pp. 1082-1097. 10.1016/j.immuni.2023.03.020

Nguyen, Thi H.O., Rowntree, Louise C., Allen, Lilith F., Chua, Brendon Y., Kedzierski, Lukasz, Lim, Chhay, Lasica, Masa, Tennakoon, G. Surekha, Saunders, Natalie R., Crane, Megan, Chee, Lynette, Seymour, John F., Anderson, Mary Ann, Whitechurch, Ashley, Clemens, E. Bridie, Zhang, Wuji, Chang, So Young, Habel, Jennifer R., Jia, Xiaoxiao, McQuilten, Hayley A., Minervina, Anastasia A., Pogorelyy, Mikhail V., Chaurasia, Priyanka, Petersen, Jan, Menon, Tejas, Hensen, Luca, Neil, Jessica A., Mordant, Francesca L., Tan, Hyon-Xhi, Cabug, Aira F., Wheatley, Adam K., Kent, Stephen J., Subbarao, Kanta, Karapanagiotidis, Theo, Huang, Han, Vo, Lynn K., Cain, Natalie L., Nicholson, Suellen, Krammer, Florian, Gibney, Grace, James, Fiona, Trevillyan, Janine M., Trubiano, Jason A., Mitchell, Jeni, Christensen, Britt, Bond, Katherine A., Williamson, Deborah A., Rossjohn, Jamie

, Crawford, Jeremy Chase, Thomas, Paul G., Thursky, Karin A., Slavin, Monica A., Tam, Constantine S., Teh, Benjamin W. and Kedzierska, Katherine 2023. Robust SARS-CoV-2 T cell responses with common TCR?? motifs toward COVID-19 vaccines in patients with hematological malignancy impacting B cells. Cell Reports Medicine 4 (4) , 101017. 10.1016/j.xcrm.2023.101017

Koutsakos, Marios, Reynaldi, Arnold, Lee, Wen Shi, Nguyen, Julie, Amarasena, Thakshila, Taiaroa, George, Kinsella, Paul, Liew, Kwee Chin, Tran, Thomas, Kent, Helen E., Tan, Hyon-Xhi, Rowntree, Louise C., Nguyen, Thi H.O., Thomas, Paul G., Kedzierska, Katherine, Petersen, Jan, Rossjohn, Jamie

, Williamson, Deborah A., Khoury, David, Davenport, Miles P., Kent, Stephen J., Wheatley, Adam K. and Juno, Jennifer A. 2023. SARS-CoV-2 breakthrough infection induces rapid memory and de novo T cell responses. Immunity 56 (4) , pp. 879-892. 10.1016/j.immuni.2023.02.017

Pan, Yue, Chandrashekaran, Indu R., Tennant, Luke, Rossjohn, Jamie

and Littler, Dene R. 2023. Inside-out: antibody-binding reveals potential folding hinge-points within the SARS-CoV-2 replication co-factor nsp9. PLoS ONE 18 (4) , e0283194. 10.1371/journal.pone.0283194

Farquhar, Rachel, Van Rhijn, Ildiko, Moody, D. Branch, Rossjohn, Jamie

and Shahine, Adam 2023. αβ T cell receptor recognition of self-phosphatidylinositol presented by CD1b. Journal of Biological Chemistry 299 (2) , 102849. 10.1016/j.jbc.2022.102849

von Borstel, Anouk, Nguyen, Thi HO, Rowntree, Louise C, Ashhurst, Thomas M, Allen, Lilith F, Howson, Lauren J, Holmes, Natasha E, Smibert, Olivia C, Trubiano, Jason A, Gordon, Claire L, Cheng, Allen C, Kent, Stephen J, Rossjohn, Jamie

, Kedzierska, Katherine and Davey, Martin S 2023. Circulating effector γδ T cell populations are associated with acute coronavirus disease 19 in unvaccinated individuals. Immunology & Cell Biology 10.1111/imcb.12623

Ashley, Caroline L., McSharry, Brian P., McWilliam, Hamish E. G., Stanton, Richard J.

, Fielding, Ceri A.

, Mathias, Rommel A., Fairlie, David P., McCluskey, James, Villadangos, Jose A., Rossjohn, Jamie

, Abendroth, Allison and Slobedman, Barry 2023. Suppression of MR1 by human cytomegalovirus inhibits MAIT cell activation. Frontiers in Immunology 14 10.3389/fimmu.2023.1107497

Purohit, Shivam K, Samer, Carolyn, McWilliam, Hamish E G, Traves, Renee, Steain, Megan, McSharry, Brian P, Kinchington, Paul R, Tscharke, David C, Villadangos, Jose A, Rossjohn, Jamie

, Abendroth, Allison and Slobedman, Barry 2023. Varicella zoster virus impairs expression of the nonclassical major histocompatibility complex class I-related gene protein (MR1). The Journal of Infectious Diseases 227 (3) , pp. 391-401. 10.1093/infdis/jiab526

Monnot, Gwennaëlle C., Wegrecki, Marcin, Cheng, Tan-Yun, Chen, Yi-Ling, Sallee, Brigitte N., Chakravarthy, Reka, Karantza, Ioanna Maria, Tin, Shin Yi, Khaleel, Alexandra E., Monga, Isha, Uwakwe, Laura N., Tillman, Alice, Cheng, Bin, Youssef, Soundos, Ng, Soo Weei, Shahine, Adam, Garcia-Vilas, Javier A., Uhlemann, Anne-Catrin, Bordone, Lindsey A., Han, Arnold, Rohde, Christine H., Ogg, Graham, Moody, D. Branch, Rossjohn, Jamie

and de Jong, Annemieke 2023. Staphylococcal phosphatidylglycerol antigens activate human T cells via CD1a. Nature Immunology 24 (1) , pp. 110-122. 10.1038/s41590-022-01375-z

Wang, Carl J.H., Awad, Wael, Liu, Ligong, Mak, Jeffrey Y.W., Veerapen, Natacha, Illing, Patricia T., Purcell, Anthony W., Eckle, Sidonia B.G., McCluskey, James, Besra, Gurdyal S., Fairlie, David P., Rossjohn, Jamie

and Le Nours, Jérôme 2022. Quantitative affinity measurement of small molecule ligand binding to major histocompatibility complex class-I–related protein 1 MR1. Journal of Biological Chemistry 298 (12) , 102714. 10.1016/j.jbc.2022.102714

Hardman, Clare S., Chen, Yi-Ling, Wegrecki, Marcin, Ng, Soo Weei, Murren, Robert, Mangat, Davinderpreet, Silva, John-Paul, Munro, Rebecca, Chan, Win Yan, O’Dowd, Victoria, Doyle, Carl, Mori, Prashant, Popplewell, Andy, Rossjohn, Jamie

, Lightwood, Daniel and Ogg, Graham S. 2022. CD1a promotes systemic manifestations of skin inflammation. Nature Communications 13 , 7535. 10.1038/s41467-022-35071-1

Sonigra, Amee, Nel, Hendrik J., Wehr, Pascale, Ramnoruth, Nishta, Patel, Swati, van Schie, Karin A., Bladen, Maxwell W., Mehdi, Ahmed M., Tesiram, Joanne, Talekar, Meghna, Rossjohn, Jamie

, Reid, Hugh H., Stuurman, Frederik E., Roberts, Helen, Vecchio, Phillip, Gourley, Ian, Rigby, Mark, Becart, Stephane, Toes, Rene E.M., Scherer, Hans Ulrich, Lê Cao, Kim-Anh, Campbell, Kim and Thomas, Ranjeny 2022. Randomized phase I trial of antigen-specific tolerizing immunotherapy with peptide/calcitriol liposomes in ACPA+ rheumatoid arthritis. JCI Insight 7 (20) , e160964. 10.1172/jci.insight.160964

Rowntree, Louise C., Nguyen, Thi H.O., Kedzierski, Lukasz, Neeland, Melanie R., Petersen, Jan, Crawford, Jeremy Chase, Allen, Lilith F., Clemens, E. Bridie, Chua, Brendon, McQuilten, Hayley A., Minervina, Anastasia A., Pogorelyy, Mikhail V., Chaurasia, Priyanka, Tan, Hyon-Xhi, Wheatley, Adam K., Jia, Xiaoxiao, Amanat, Fatima, Krammer, Florian, Allen, E. Kaitlynn, Sonda, Sabrina, Flanagan, Katie L., Jumarang, Jaycee, Pannaraj, Pia S., Licciardi, Paul V., Kent, Stephen J., Bond, Katherine A., Williamson, Deborah A., Rossjohn, Jamie

, Thomas, Paul G., Tosif, Shidan, Crawford, Nigel W., van de Sandt, Carolien E. and Kedzierska, Katherine 2022. SARS-CoV-2-specific T cell memory with common TCRαβ motifs is established in unvaccinated children who seroconvert after infection. Immunity 55 (7) , pp. 1299-1315. 10.1016/j.immuni.2022.06.003

Wegrecki, Marcin, Ocampo, Tonatiuh A., Gunasinghe, Sachith D., von Borstel, Anouk, Tin, Shin Yi, Reijneveld, Josephine F., Cao, Thinh-Phat, Gully, Benjamin S., Le Nours, Jérôme, Moody, D. Branch, Van Rhijn, Ildiko and Rossjohn, Jamie

2022. Atypical sideways recognition of CD1a by autoreactive γδ T cell receptors. Nature Communications 13 (1) , 3872. 10.1038/s41467-022-31443-9

Sakari, Moona, Tran, Mai T., Rossjohn, Jamie

, Pulliainen, Arto T., Beddoe, Travis and Littler, Dene R. 2022. Crystal structures of pertussis toxin with NAD+ and analogs provide structural insights into the mechanism of its cytosolic ADP-ribosylation activity. Journal of Biological Chemistry 298 (5) , 101892. 10.1016/j.jbc.2022.101892

McMurray, Jack L., von Borstel, Anouk, Taher, Taher E., Syrimi, Eleni, Taylor, Graham S., Sharif, Maria, Rossjohn, Jamie

, Remmerswaal, Ester B.M., Bemelman, Frederike J., Vieira Braga, Felipe A., Chen, Xi, Teichmann, Sarah A., Mohammed, Fiyaz, Berry, Andrea A., Lyke, Kirsten E., Williamson, Kim C., Stubbington, Michael J.T., Davey, Martin S., Willcox, Carrie R. and Willcox, Benjamin E. 2022. Transcriptional profiling of human Vδ1 T cells reveals a pathogen-driven adaptive differentiation program. Cell Reports 39 (8) , 110858. 10.1016/j.celrep.2022.110858

Zhang, Wuji, Kedzierski, Lukasz, Chua, Brendon Y., Wheatley, Adam K., Rowntree, Louise, Allen, Lilith, Petersen, Jan, Chaurasia, Priyanka, Mettelman, Robert, Miller, Adrian, Thomas, Paul G., Rossjohn, Jamie

, Subbarao, Kanta, Kent, Stephen J., Nelson, Jane, Davies, Jane, Nguyen, Thi H.O. and Kedzierska, Katherine 2022. Robust and prototypical immune responses towards COVID-19 BNT162b2 vaccines in Indigenous people. The Journal of Immunology 208 (1_Supp) , 65.13. 10.4049/jimmunol.208.Supp.65.13

Meeuwsen, Miranda H., Wouters, Anne K., Hagedoorn, Renate S., Kester, Michel G. D., Remst, Dennis F. G., van der Steen, Dirk M., de Ru, Arnoud, van Veelen, Peter A., Rossjohn, Jamie

, Gras, Stephanie, Falkenburg, J. H. Frederik and Heemskerk, Mirjam H. M. 2022. Cutting Edge: Unconventional CD8+ T Cell Recognition of a Naturally Occurring HLA-A*02:01?Restricted 20mer Epitope. Journal of Immunology 208 (8) , pp. 1851-1856. 10.4049/jimmunol.2101208

Ciacchi, Laura, Farenc, Carine, Dahal-Koirala, Shiva, Petersen, Jan, Sollid, Ludvig M., Reid, Hugh H. and Rossjohn, Jamie

2022. Structural basis of T cell receptor specificity and cross-reactivity of two HLA-DQ2.5-restricted gluten epitopes in celiac disease. Journal of Biological Chemistry 298 (3) , 101619. 10.1016/j.jbc.2022.101619

Suliman, Sara, Kjer-Nielsen, Lars, Iwany, Sarah K., Lopez Tamara, Kattya, Loh, Liyen, Grzelak, Ludivine, Kedzierska, Katherine, Ocampo, Tonatiuh A., Corbett, Alexandra J., McCluskey, James, Rossjohn, Jamie

, León, Segundo R., Calderon, Roger, Lecca-Garcia, Leonid, Murray, Megan B., Moody, D. Branch and Van Rhijn, Ildiko 2022. Dual TCR-α expression on mucosal-associated invariant T cells as a potential confounder of TCR interpretation. Journal of Immunology 208 (6) , pp. 1389-1395. 10.4049/jimmunol.2100275

Habel, Jennifer R., Nguyen, Andrea T., Rowntree, Louise C., Szeto, Christopher, Mifsud, Nicole A., Clemens, E. Bridie, Loh, Liyen, Chen, Weisan, Rockman, Steve, Nelson, Jane, Davies, Jane, Miller, Adrian, Tong, Steven Y. C., Rossjohn, Jamie

, Gras, Stephanie, Purcell, Anthony W., Hensen, Luca, Kedzierska, Katherine and Illing, Patricia T. 2022. HLA-A*11:01-restricted CD8+ T cell immunity against influenza A and influenza B viruses in Indigenous and non-Indigenous people. PLoS Pathogens 18 (3) , e1010337. 10.1371/journal.ppat.1010337

Littler, Dene R., Liu, Miaomiao, McAuley, Julie L., Lowery, Shea A., Illing, Patricia T., Gully, Benjamin S., Purcell, Anthony W., Chandrashekaran, Indu R., Perlman, Stanley, Purcell, Damian F.J., Quinn, Ronald J. and Rossjohn, Jamie

2021. A natural product compound inhibits coronaviral replication in vitro by binding to the conserved Nsp9 SARS-CoV-2 protein. Journal of Biological Chemistry 297 (6) , 101362. 10.1016/j.jbc.2021.101362

Oh, Sungwhan F., Praveena, T., Song, Heebum, Yoo, Ji-Sun, Jung, Da-Jung, Erturk-Hasdemir, Deniz, Hwang, Yoon Soo, Lee, ChangWon C., Le Nours, Jérôme, Kim, Hyunsoo, Lee, Jesang, Blumberg, Richard S., Rossjohn, Jamie

, Park, Seung Bum and Kasper, Dennis L. 2021. Host immunomodulatory lipids created by symbionts from dietary amino acids. Nature 600 (7888) , 302–307. 10.1038/s41586-021-04083-0

Reijneveld, Josephine F., Marino, Laura, Cao, Thinh-Phat, Cheng, Tan-Yun, Dam, Dennis, Shahine, Adam, Witte, Martin D., Filippov, Dmitri V., Suliman, Sara, van der Marel, Gijsbert A., Moody, D. Branch, Minnaard, Adriaan J., Rossjohn, Jamie

, Codée, Jeroen D.C. and Van Rhijn, Ildiko 2021. Rational design of a hydrolysis-resistant mycobacterial phosphoglycolipid antigen presented by CD1c to T cells. Journal of Biological Chemistry 297 (4) , 101197. 10.1016/j.jbc.2021.101197

Rowntree, Louise C, Petersen, Jan, Juno, Jennifer A, Chaurasia, Priyanka, Wragg, Kathleen, Koutsakos, Marios, Hensen, Luca, Wheatley, Adam K, Kent, Stephen J, Rossjohn, Jamie

, Kedzierska, Katherine and Nguyen, Thi HO 2021. SARS-CoV-2-specific CD8+ T-cell responses and TCR signatures in the context of a prominent HLA-A*24:02 allomorph. Immunology & Cell Biology 99 (9) , pp. 990-1000. 10.1111/imcb.12482

Littler, Dene R., Mohanty, Biswaranjan, Lowery, Shea A., Colson, Rhys N., Gully, Benjamin S., Perlman, Stanley, Scanlon, Martin J. and Rossjohn, Jamie

2021. Binding of a pyrimidine RNA base-mimic to SARS-CoV-2 nonstructural protein 9. Journal of Biological Chemistry 297 (3) , 101018. 10.1016/j.jbc.2021.101018

Chaurasia, Priyanka, Nguyen, Thi H.O., Rowntree, Louise C., Juno, Jennifer A., Wheatley, Adam K., Kent, Stephen J., Kedzierska, Katherine, Rossjohn, Jamie

and Petersen, Jan 2021. Structural basis of biased T cell receptor recognition of an immunodominant HLA-A2 epitope of the SARS-CoV-2 spike protein. Journal of Biological Chemistry 297 (3) , 101065. 10.1016/j.jbc.2021.101065

Gully, Benjamin S., Rossjohn, Jamie

and Davey, Martin S. 2021. Our evolving understanding of the role of the γδ T cell receptor in γδ T cell mediated immunity. Biochemical Society Transactions 10.1042/BST20200890

Mayassi, Toufic, Barreiro, Luis B., Rossjohn, Jamie

and Jabri, Bana 2021. A multilayered immune system through the lens of unconventional T cells. Nature 595 , pp. 501-510. 10.1038/s41586-021-03578-0

Zhao, Zhe, Wang, Huimeng, Shi, Mai, Zhu, Tianyuan, Pediongco, Troi, Lim, Xin Yi, Meehan, Bronwyn S., Nelson, Adam G., Fairlie, David P., Mak, Jeffrey Y. W., Eckle, Sidonia B. G., de Lima Moreira, Marcela, Tumpach, Carolin, Bramhall, Michael, Williams, Cameron G., Lee, Hyun Jae, Haque, Ashraful, Evrard, Maximilien, Rossjohn, Jamie

, McCluskey, James, Corbett, Alexandra J. and Chen, Zhenjun 2021. Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection. Nature Communications 12 , 4355. 10.1038/s41467-021-24570-2

Hensen, Luca, Illing, Patricia T., Bridie Clemens, E., Nguyen, Thi H. O., Koutsakos, Marios, van de Sandt, Carolien E., Mifsud, Nicole A., Nguyen, Andrea T., Szeto, Christopher, Chua, Brendon Y., Halim, Hanim, Rizzetto, Simone, Luciani, Fabio, Loh, Liyen, Grant, Emma J., Saunders, Phillipa M., Brooks, Andrew G., Rockman, Steve, Kotsimbos, Tom C., Cheng, Allen C., Richards, Michael, Westall, Glen P., Wakim, Linda M., Loudovaris, Thomas, Mannering, Stuart I., Elliott, Michael, Tangye, Stuart G., Jackson, David C., Flanagan, Katie L., Rossjohn, Jamie

, Gras, Stephanie, Davies, Jane, Miller, Adrian, Tong, Steven Y. C., Purcell, Anthony W. and Kedzierska, Katherine 2021. CD8+ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph. Nature Communications 12 (1) , 2931. 10.1038/s41467-021-23212-x

Nguyen, Thi H.O., Rowntree, Louise C., Petersen, Jan, Chua, Brendon Y., Hensen, Luca, Kedzierski, Lukasz, van de Sandt, Carolien E., Chaurasia, Priyanka, Tan, Hyon-Xhi, Habel, Jennifer R., Zhang, Wuji, Allen, Lilith F., Earnest, Linda, Mak, Kai Yan, Juno, Jennifer A., Wragg, Kathleen, Mordant, Francesca L., Amanat, Fatima, Krammer, Florian, Mifsud, Nicole A., Doolan, Denise L., Flanagan, Katie L., Sonda, Sabrina, Kaur, Jasveen, Wakim, Linda M., Westall, Glen P., James, Fiona, Mouhtouris, Effie, Gordon, Claire L., Holmes, Natasha E., Smibert, Olivia C., Trubiano, Jason A., Cheng, Allen C., Harcourt, Peter, Clifton, Patrick, Crawford, Jeremy Chase, Thomas, Paul G., Wheatley, Adam K., Kent, Stephen J., Rossjohn, Jamie

, Torresi, Joseph and Kedzierska, Katherine 2021. CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope display high naive precursor frequency and TCR promiscuity. Immunity 54 (5) , pp. 1066-1082. 10.1016/j.immuni.2021.04.009

Nguyen, Thi H. O., Koutsakos, Marios, van de Sandt, Carolien E., Crawford, Jeremy Chase, Loh, Liyen, Sant, Sneha, Grzelak, Ludivine, Allen, Emma K., Brahm, Tim, Clemens, E. Bridie, Auladell, Maria, Hensen, Luca, Wang, Zhongfang, Nüssing, Simone, Jia, Xiaoxiao, Günther, Patrick, Wheatley, Adam K., Kent, Stephen J., Aban, Malet, Deng, Yi-Mo, Laurie, Karen L., Hurt, Aeron C., Gras, Stephanie, Rossjohn, Jamie

, Crowe, Jane, Xu, Jianqing, Jackson, David, Brown, Lorena E., La Gruta, Nicole, Chen, Weisan, Doherty, Peter C., Turner, Stephen J., Kotsimbos, Tom C., Thomas, Paul G., Cheng, Allen C. and Kedzierska, Katherine 2021. Immune cellular networks underlying recovery from influenza virus infection in acute hospitalized patients. Nature Communications 12 (1) , 2691. 10.1038/s41467-021-23018-x

Mifsud, Nicole A., Illing, Patricia T., Lai, Jeffrey W., Fettke, Heidi, Hensen, Luca, Huang, Ziyi, Rossjohn, Jamie

, Vivian, Julian P., Kwan, Patrick and Purcell, Anthony W. 2021. Carbamazepine induces focused T cell responses in resolved Stevens-Johnson syndrome and toxic epidermal necrolysis cases but does not perturb the immunopeptidome for T cell recognition. Frontiers in Immunology 12 , 653710. 10.3389/fimmu.2021.653710

Moradi, Shoeib, Stankovic, Sanda, O'Connor, Geraldine M., Pymm, Phillip, MacLachlan, Bruce J., Faoro, Camilla, Retière, Christelle, Sullivan, Lucy C., Saunders, Philippa M., Widjaja, Jacqueline, Cox-Livingstone, Shea, Rossjohn, Jamie

, Brooks, Andrew G. and Vivian, Julian P. 2021. Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C. Nature Communications 12 (1) , 2173. 10.1038/s41467-021-22359-x

Howson, Lauren J., Li, Jasmine, von Borstel, Anouk, Barugahare, Adele, Mak, Jeffrey Y. W., Fairlie, David P., McCluskey, James, Turner, Stephen J., Davey, Martin S. and Rossjohn, Jamie

2021. Mucosal-associated invariant T cell effector function is an intrinsic cell property that can be augmented by the metabolic cofactor α-Ketoglutarate. Journal of Immunology 206 (7) , pp. 1425-1435. 10.4049/jimmunol.2001048

Saunders, Philippa M., MacLachlan, Bruce J., Widjaja, Jacqueline, Wong, Shu Cheng, Oates, Clare V. L., Rossjohn, Jamie

, Vivian, Julian P. and Brooks, Andrew G. 2021. The role of the HLA class I α2 helix in determining ligand hierarchy for the killer cell Ig-like receptor 3DL1. Journal of Immunology 206 (4) , pp. 849-860. 10.4049/jimmunol.2001109

Wirasinha, Rushika C., Davies, Ainsley R., Srivastava, Monika, Sheridan, Julie M., Sng, Xavier Y.X., Delmonte, Ottavia M., Dobbs, Kerry, Loh, Khai L., Miosge, Lisa A., Lee, Cindy Eunhee, Chand, Rochna, Chan, Anna, Yap, Jin Yan, Keller, Michael D., Chen, Karin, Rossjohn, Jamie

, La Gruta, Nicole L., Vinuesa, Carola G., Reid, Hugh H., Lionakis, Michail S., Notarangelo, Luigi D., Gray, Daniel H.D., Goodnow, Christopher C., Cook, Matthew C. and Daley, Stephen R. 2021. Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility. Journal of Experimental Medicine 218 (2) , e20200476. 10.1084/jem.20200476

Cotton, Rachel N., Cheng, Tan-Yun, Wegrecki, Marcin, Le Nours, Jérôme, Orgill, Dennis P., Pomahac, Bohdan, Talbot, Simon G., Willis, Richard A., Altman, John D., de Jong, Annemieke, Ogg, Graham, Van Rhijn, Ildiko, Rossjohn, Jamie

, Clark, Rachael A. and Moody, D. Branch 2021. Human skin is colonized by T cells that recognize CD1a independently of lipid. Journal of Clinical Investigation 131 (1) , e140706. 10.1172/JCI140706

McWilliam, Hamish E. G., Mak, Jeffrey Y. W., Awad, Wael, Zorkau, Matthew, Cruz-Gomez, Sebastian, Lim, Hui Jing, Yan, Yuting, Wormald, Sam, Dagley, Laura F., Eckle, Sidonia B. G., Corbett, Alexandra J., Liu, Haiyin, Li, Shihan, Reddiex, Scott J. J., Mintern, Justine D., Liu, Ligong, McCluskey, James, Rossjohn, Jamie

, Fairlie, David P. and Villadangos, Jose A. 2020. Endoplasmic reticulum chaperones stabilize ligand-receptive MR1 molecules for efficient presentation of metabolite antigens. Proceedings of the National Academy of Sciences 117 (40) , pp. 24974-24985. 10.1073/pnas.2011260117

Assmus, Lisa M., Guan, Jing, Wu, Ting, Farenc, Carine, Sng, Xavier Y. X., Zareie, Pirooz, Nguyen, Angela, Nguyen, Andrea T., Tscharke, David C., Thomas, Paul G., Rossjohn, Jamie

, Gras, Stephanie, Croft, Nathan P., Purcell, Anthony W. and La Gruta, Nicole L. 2020. Overlapping peptides elicit distinct CD8+ T cell responses following Influenza A virus infection. Journal of Immunology 205 (7) , pp. 1731-1742. 10.4049/jimmunol.2000689

Habel, Jennifer R., Nguyen, Thi H. O., van de Sandt, Carolien E., Juno, Jennifer A., Chaurasia, Priyanka, Wragg, Kathleen, Koutsakos, Marios, Hensen, Luca, Jia, Xiaoxiao, Chua, Brendon, Zhang, Wuji, Tan, Hyon-Xhi, Flanagan, Katie L., Doolan, Denise L., Torresi, Joseph, Chen, Weisan, Wakim, Linda M., Cheng, Allen C., Doherty, Peter C., Petersen, Jan, Rossjohn, Jamie

, Wheatley, Adam K., Kent, Stephen J., Rowntree, Louise C. and Kedzierska, Katherine 2020. Suboptimal SARS-CoV-2-specific CD8+ T cell response associated with the prominent HLA-A*02:01 phenotype. Proceedings of the National Academy of Sciences 117 (39) , pp. 24384-24391. 10.1073/pnas.2015486117

Suliman, Sara, Gela, Anele, Mendelsohn, Simon C., Iwany, Sarah K., Tamara, Kattya Lopez, Mabwe, Simbarashe, Bilek, Nicole, Darboe, Fatoumatta, Fisher, Michelle, Corbett, Alexandra J., Kjer-Nielsen, Lars, Eckle, Sidonia B. G., Huang, Chuan-Chin, Zhang, Zibiao, Lewinsohn, David M., McCluskey, James, Rossjohn, Jamie

, Hatherill, Mark, León, Segundo R., Calderon, Roger I., Lecca, Leonid, Murray, Megan, Scriba, Thomas J., Van Rhijn, Ildiko and Moody, D. Branch 2020. Peripheral blood mucosal-associated invariant T Cells in tuberculosis patients and healthy mycobacterium tuberculosis-exposed controls. Journal of Infectious Diseases 222 (6) , pp. 995-1007. 10.1093/infdis/jiaa173

Rowntree, Louise C., Nguyen, Thi H. O., Farenc, Carine, Halim, Hanim, Hensen, Luca, Rossjohn, Jamie

, Kotsimbos, Tom C., Purcell, Anthony W., Kedzierska, Katherine, Gras, Stephanie and Mifsud, Nicole A. 2020. A shared TCR bias toward an immunogenic EBV epitope dominates in HLA-B*07:02–expressing individuals. Journal of Immunology 205 (6) , pp. 1524-1534. 10.4049/jimmunol.2000249

Aguilar, Oscar A., Tanaka, Miho, Balaji, Gautham R., Berry, Richard, Rossjohn, Jamie

, Lanier, Lewis L. and Carlyle, James R. 2020. Tetramer immunization and selection followed by CELLISA screening to generate monoclonal antibodies against the mouse cytomegalovirus m12 immunoevasin. Journal of Immunology 205 (6) , pp. 1709-1717. 10.4049/jimmunol.2000687

Reijneveld, Josephine F., Ocampo, Tonatiuh A., Shahine, Adam, Gully, Benjamin S., Vantourout, Pierre, Hayday, Adrian C., Rossjohn, Jamie

, Moody, D. Branch and Van Rhijn, Ildiko 2020. Human γδ T cells recognize CD1b by two distinct mechanisms. Proceedings of the National Academy of Sciences 117 (37) , pp. 22933-22952. 10.1073/pnas.2010545117

Lameris, Roeland, Shahine, Adam, Pellicci, Daniel G., Uldrich, Adam P., Gras, Stephanie, Le Nours, Jérôme, Groen, Richard W. J., Vree, Jana, Reddiex, Scott J. J., Quiñones-Parra, Sergio M., Richardson, Stewart K., Howell, Amy R., Zweegman, Sonja, Godfrey, Dale I., de Gruijl, Tanja D., Rossjohn, Jamie

and van der Vliet, Hans J. 2020. A single-domain bispecific antibody targeting CD1d and the NKT T-cell receptor induces a potent antitumor response. Nature Cancer 1 (11) , pp. 1054-1065. 10.1038/s43018-020-00111-6

Schultz-Cherry, Stacey, Sant, Sneha, Quiñones-Parra, Sergio M., Koutsakos, Marios, Grant, Emma J., Loudovaris, Thomas, Mannering, Stuart I., Crowe, Jane, van de Sandt, Carolien E., Rimmelzwaan, Guus F., Rossjohn, Jamie

, Gras, Stephanie, Loh, Liyen, Nguyen, Thi H. O. and Kedzierska, Katherine 2020. HLA-B*27:05 alters immunodominance hierarchy of universal influenza-specific CD8+ T cells. PLoS Pathogens 16 (8) , e1008714. 10.1371/journal.ppat.1008714

Junghans, Victoria, Chouliara, Manto, Santos, Ana Mafalda, Hatherley, Deborah, Petersen, Jan, Dam, Tommy, Svensson, Lena M., Rossjohn, Jamie

, Davis, Simon J. and Jönsson, Peter 2020. Effects of a local auxiliary protein on the two-dimensional affinity of a TCR–peptide MHC interaction. Journal of Cell Science 133 (15) , jcs245985. 10.1242/jcs.245985

Littler, Dene R., Gully, Benjamin S., Colson, Rhys N. and Rossjohn, Jamie

2020. Crystal structure of the SARS-CoV-2 non-structural protein 9, Nsp9. iScience 23 (7) , 101258. 10.1016/j.isci.2020.101258

Toubal, Amine, Kiaf, Badr, Beaudoin, Lucie, Cagninacci, Lucie, Rhimi, Moez, Fruchet, Blandine, da Silva, Jennifer, Corbett, Alexandra J., Simoni, Yannick, Lantz, Olivier, Rossjohn, Jamie

, McCluskey, James, Lesnik, Philippe, Maguin, Emmanuelle and Lehuen, Agnès 2020. Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity. Nature Communications 11 (1) , 3755. 10.1038/s41467-020-17307-0

Howson, Lauren J., Awad, Wael, von Borstel, Anouk, Lim, Hui Jing, McWilliam, Hamish E. G., Sandoval-Romero, Maria L., Majumdar, Shamik, Hamzeh, Abdul Rezzak, Andrews, Thomas D., McDermott, David H., Murphy, Philip M., Le Nours, Jérôme, Mak, Jeffrey Y. W., Liu, Ligong, Fairlie, David P., McCluskey, James, Villadangos, Jose A., Cook, Matthew C., Turner, Stephen J., Davey, Martin S., Ojaimi, Samar and Rossjohn, Jamie

2020. Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1. Science Immunology 5 (49) , eabc9492. 10.1126/sciimmunol.abc9492

Saunders, Philippa M., MacLachlan, Bruce J., Pymm, Phillip, Illing, Patricia T., Deng, Yuanchen, Wong, Shu Cheng, Oates, Clare V. L., Purcell, Anthony W., Rossjohn, Jamie

, Vivian, Julian P. and Brooks, Andrew G. 2020. The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function. Proceedings of the National Academy of Sciences 117 (21) , pp. 11636-11647. 10.1073/pnas.1920570117

Awad, Wael, Ler, Geraldine J. M., Xu, Weijun, Keller, Andrew N., Mak, Jeffrey Y. W., Lim, Xin Yi, Liu, Ligong, Eckle, Sidonia B. G., Le Nours, Jérôme, McCluskey, James, Corbett, Alexandra J., Fairlie, David P. and Rossjohn, Jamie

2020. The molecular basis underpinning the potency and specificity of MAIT cell antigens. Nature Immunology 21 (4) , pp. 400-411. 10.1038/s41590-020-0616-6

Salio, Mariolina, Awad, Wael, Veerapen, Natacha, Gonzalez-Lopez, Claudia, Kulicke, Corinna, Waithe, Dominic, Martens, Anne W. J., Lewinsohn, David M., Hobrath, Judith V., Cox, Liam R., Rossjohn, Jamie

, Besra, Gurdyal S. and Cerundolo, Vincenzo 2020. Ligand-dependent downregulation of MR1 cell surface expression. Proceedings of the National Academy of Sciences 117 (19) , pp. 10465-10475. 10.1073/pnas.2003136117

Fugger, Lars, Jensen, Lise Torp and Rossjohn, Jamie

2020. Challenges, progress, and prospects of developing therapies to treat autoimmune diseases. Cell 181 (1) , pp. 63-80. 10.1016/j.cell.2020.03.007

McSharry, Brian P., Samer, Carolyn, McWilliam, Hamish E.G., Ashley, Caroline L., Yee, Michael B., Steain, Megan, Liu, Ligong, Fairlie, David P., Kinchington, Paul R., McCluskey, James, Abendroth, Allison, Villadangos, Jose A., Rossjohn, Jamie

and Slobedman, Barry 2020. Virus-mediated suppression of the antigen presentation Molecule MR1. Cell Reports 30 (9) , 2948-2962e4. 10.1016/j.celrep.2020.02.017

Loh, Liyen, Gherardin, Nicholas A., Sant, Sneha, Grzelak, Ludivine, Crawford, Jeremy Chase, Bird, Nicola L., Koay, Hui-Fern, van de Sandt, Carolien E., Moreira, Marcela L., Lappas, Martha, Allen, E. Kaitlynn, Crowe, Jane, Loudovaris, Thomas, Flanagan, Katie L., Quinn, Kylie M., Rossjohn, Jamie

, Thomas, Paul G., Eckle, Sidonia B. G., McCluskey, James, Godfrey, Dale I. and Kedzierska, Katherine 2020. Human mucosal-associated invariant T cells in older individuals display expanded TCRαβ clonotypes with potent antimicrobial responses. Journal of Immunology 204 (5) , pp. 1119-1133. 10.4049/jimmunol.1900774

Crowther, Michael D., Dolton, Garry, Legut, Mateusz, Caillaud, Marine E., Lloyd, Angharad, Attaf, Meriem, Galloway, Sarah A. E., Rius, Cristina, Farrell, Colin P., Szomolay, Barbara

, Ager, Ann

, Parker, Alan L.

, Fuller, Anna, Donia, Marco, McCluskey, James, Rossjohn, Jamie

, Svane, Inge Marie, Phillips, John D. and Sewell, Andrew K.

2020. Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1. Nature Immunology 21 , 178 - 185. 10.1038/s41590-019-0578-8

Berry, Richard, Watson, Gabrielle M., Jonjic, Stipan, Degli-Esposti, Mariapia A. and Rossjohn, Jamie

2020. Modulation of innate and adaptive immunity by cytomegaloviruses. Nature Reviews Immunology 20 , pp. 113-127. 10.1038/s41577-019-0225-5

Rowntree, Louise C., van den Heuvel, Heleen, Sun, Jessica, D'Orsogna, Lloyd J., Nguyen, Thi H. O., Claas, Frans H. J., Rossjohn, Jamie

, Kotsimbos, Tom C., Purcell, Anthony W. and Mifsud, Nicole A. 2020. Preferential HLA-B27 allorecognition displayed by multiple cross-reactive antiviral CD8+ T cell receptors. Frontiers in Immunology 11 , 248. 10.3389/fimmu.2020.00248

Ting, Yi Tian, Dahal-Koirala, Shiva, Kim, Hui Shi Keshia, Qiao, Shuo-Wang, Neumann, Ralf S., Lundin, Knut E. A., Petersen, Jan, Reid, Hugh H., Sollid, Ludvig M. and Rossjohn, Jamie

2020. A molecular basis for the T cell response in HLA-DQ2.2 mediated celiac disease. Proceedings of the National Academy of Sciences 117 (6) , pp. 3063-3073. 10.1073/pnas.1914308117

Petersen, Jan, Ciacchi, Laura, Tran, Mai T., Loh, Khai Lee, Kooy-Winkelaar, Yvonne, Croft, Nathan P., Hardy, Melinda Y., Chen, Zhenjun, McCluskey, James, Anderson, Robert P., Purcell, Anthony W., Tye-Din, Jason A., Koning, Frits, Reid, Hugh H. and Rossjohn, Jamie

2020. T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease. Nature Structural and Molecular Biology 27 (1) , pp. 49-61. 10.1038/s41594-019-0353-4

Nicolai, Sarah, Wegrecki, Marcin, Cheng, Tan-Yun, Bourgeois, Elvire A., Cotton, Rachel N., Mayfield, Jacob A., Monnot, Gwennaëlle C., Le Nours, Jérôme, Van Rhijn, Ildiko, Rossjohn, Jamie

, Moody, D. Branch and de Jong, Annemieke 2020. Human T cell response to CD1a and contact dermatitis allergens in botanical extracts and commercial skin care products. Science Immunology 5 (43) , eaax5430. 10.1126/sciimmunol.aax5430

Chen, Zhenjun, Wang, Huimeng, D'Souza, Criselle, Koay, Hui-Fern, Meehan, Bronwyn, Zhao, Zhe, Pediongco, Troi, Shi, Mai, Zhu, Tianyuan, Wang, Bingjie, Kjer-Nielsen, Lars, Eckle, Sidonia B. G., Rossjohn, Jamie

, Fairlie, David P., Godfrey, Dale I., Strugnell, Richard A., McCluskey, James and Corbett, Alexandra J. 2019. Characterization and purification of mouse mucosal-associated invariant T (MAIT) cells. Current Protocols in Immunology 127 (1) , e89. 10.1002/cpim.89

Souter, Michael N.T., Loh, Liyen, Li, Shihan, Meehan, Bronwyn S., Gherardin, Nicholas A., Godfrey, Dale I., Rossjohn, Jamie

, Fairlie, David P., Kedzierska, Katherine, Pellicci, Daniel G., Chen, Zhenjun, Kjer-Nielsen, Lars, Corbett, Alexandra J., McCluskey, James and Eckle, Sidonia B. G. 2019. Characterization of Human Mucosal-associated Invariant T (MAIT) cells. Current Protocols in Immunology 127 (1) , e90. 10.1002/cpim.90

Picarda, Elodie, Bézie, Séverine, Usero, Lorena, Ossart, Jason, Besnard, Marine, Halim, Hanim, Echasserieau, Klara, Usal, Claire, Rossjohn, Jamie

, Bernardeau, Karine, Gras, Stéphanie and Guillonneau, Carole 2019. Cross-reactive donor-specific CD8+ Tregs efficiently prevent transplant rejection. Cell Reports 29 (13) , 4245-4255.e6. 10.1016/j.celrep.2019.11.106

Le Nours, Jérôme, Gherardin, Nicholas A., Ramarathinam, Sri H., Awad, Wael, Wiede, Florian, Gully, Benjamin S., Khandokar, Yogesh, Praveena, T., Wubben, Jacinta M., Sandow, Jarrod J., Webb, Andrew I., von Borstel, Anouk, Rice, Michael T., Redmond, Samuel J., Seneviratna, Rebecca, Sandoval-Romero, Maria L., Li, Shihan, Souter, Michael N. T., Eckle, Sidonia B. G., Corbett, Alexandra J., Reid, Hugh H., Liu, Ligong, Fairlie, David P., Giles, Edward M., Westall, Glen P., Tothill, Richard W., Davey, Martin S., Berry, Richard, Tiganis, Tony, McCluskey, James, Pellicci, Daniel G., Purcell, Anthony W., Uldrich, Adam P., Godfrey, Dale I. and Rossjohn, Jamie

2019. A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1. Science 366 (6472) , pp. 1522-1527. 10.1126/science.aav3900

Reinink, Peter, Shahine, Adam, Gras, Stephanie, Cheng, Tan-Yun, Farquhar, Rachel, Lopez, Kattya, Suliman, Sara A., Reijneveld, Josephine F., Le Nours, Jérôme, Tan, Li Lynn, León, Segundo R., Jimenez, Judith, Calderon, Roger, Lecca, Leonid, Murray, Megan B., Rossjohn, Jamie

, Moody, D. Branch and Van Rhijn, Ildiko 2019. A TCR β-Chain Motif Biases toward Recognition of Human CD1 Proteins. Journal of Immunology 203 (12) , pp. 3395-3046. 10.4049/jimmunol.1900872

van de Sandt, C. E., Clemens, E. B., Grant, E. J., Rowntree, L. C., Sant, S., Halim, H., Crowe, J., Cheng, A. C., Kotsimbos, T. C., Richards, M., Miller, A., Tong, S. Y. C., Rossjohn, J.

, Nguyen, T. H. O., Gras, S., Chen, W. and Kedzierska, K. 2019. Challenging immunodominance of influenza-specific CD8+ T cell responses restricted by the risk-associated HLA-A*68:01 allomorph. Nature Communications 10 (1) , 5579. 10.1038/s41467-019-13346-4

Almeida, Catarina F., Sundararaj, Srinivasan, Le Nours, Jérôme, Praveena, T., Cao, Benjamin, Burugupalli, Satvika, Smith, Dylan G. M., Patel, Onisha, Brigl, Manfred, Pellicci, Daniel G., Williams, Spencer J., Uldrich, Adam P., Godfrey, Dale I. and Rossjohn, Jamie

2019. Distinct CD1d docking strategies exhibited by diverse Type II NKT cell receptors. Nature Communications 10 (1) , 5242. 10.1038/s41467-019-12941-9

Lim Kam Sian, Terry C. C., Indumathy, Saranjah, Halim, Hanim, Greule, Anja, Cryle, Max J., Bowness, Paul, Rossjohn, Jamie

, Gras, Stephanie, Purcell, Anthony W. and Schittenhelm, Ralf B. 2019. Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation. Journal of Biological Chemistry 294 (52) , pp. 20185-20195. 10.1074/jbc.RA119.010257

Wang, Huimeng, Kjer-Nielsen, Lars, Shi, Mai, D?Souza, Criselle, Pediongco, Troi J., Cao, Hanwei, Kostenko, Lyudmila, Lim, Xin Yi, Eckle, Sidonia B. G., Meehan, Bronwyn S., Zhu, Tianyuan, Wang, Bingjie, Zhao, Zhe, Mak, Jeffrey Y. W., Fairlie, David P., Teng, Michele W. L., Rossjohn, Jamie

, Yu, Di, de St Groth, Barbara Fazekas, Lovrecz, George, Lu, Louis, McCluskey, James, Strugnell, Richard A., Corbett, Alexandra J. and Chen, Zhenjun 2019. IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection. Science Immunology 4 (41) , eaaw0402. 10.1126/sciimmunol.aaw0402

Deuss, Felix A., Watson, Gabrielle M., Goodall, Katharine J., Leece, Isobel, Chatterjee, Sayantani, Fu, Zhihui, Thaysen-Andersen, Morten, Andrews, Daniel M., Rossjohn, Jamie

and Berry, Richard 2019. Structural basis for the recognition of nectin-like protein-5 by the human-activating immune receptor, DNAM-1. Journal of Biological Chemistry 294 (33) , pp. 12534-12546. 10.1074/jbc.RA119.009261

Niehrs, Annika, Garcia-Beltran, Wilfredo F., Norman, Paul J., Watson, Gabrielle M., Hölzemer, Angelique, Chapel, Anaïs, Richert, Laura, Pommerening-Röser, Andreas, Körner, Christian, Ozawa, Mikki, Martrus, Glòria, Rossjohn, Jamie

, Lee, Jar-How, Berry, Richard, Carrington, Mary and Altfeld, Marcus 2019. A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44. Nature Immunology 20 (9) , pp. 1129-1137. 10.1038/s41590-019-0448-4

Schinkelshoek, M.S., Fronczek, R., Kooy-Winkelaar, E.M.C., Petersen, J., Reid, H.H., van der Heide, A., Drijfhout, J.W., Rossjohn, Jamie

, Lammers, G.J. and Koning, F. 2019. H1N1 hemagglutinin-specific HLA-DQ6-restricted CD4+ T cells can be readily detected in narcolepsy type 1 patients and healthy controls. Journal of Neuroimmunology 332 , pp. 167-175. 10.1016/j.jneuroim.2019.04.009

Koutsakos, Marios, McWilliam, Hamish E. G., Aktepe, Turgut E., Fritzlar, Svenja, Illing, Patricia T., Mifsud, Nicole A., Purcell, Anthony W., Rockman, Steve, Reading, Patrick C., Vivian, Julian P., Rossjohn, Jamie

, Brooks, Andrew G., Mackenzie, Jason M., Mintern, Justine D., Villadangos, Jose A., Nguyen, Thi H. O. and Kedzierska, Katherine 2019. Downregulation of MHC class I expression by influenza A and B viruses. Frontiers in Immunology 10 , -. 10.3389/fimmu.2019.01158

Koutsakos, Marios, Illing, Patricia T., Nguyen, Thi H. O., Mifsud, Nicole A., Crawford, Jeremy Chase, Rizzetto, Simone, Eltahla, Auda A., Clemens, E. Bridie, Sant, Sneha, Chua, Brendon Y., Wong, Chinn Yi, Allen, E. Kaitlynn, Teng, Don, Dash, Pradyot, Boyd, David F., Grzelak, Ludivine, Zeng, Weiguang, Hurt, Aeron C., Barr, Ian, Rockman, Steve, Jackson, David C., Kotsimbos, Tom C., Cheng, Allen C., Richards, Michael, Westall, Glen P., Loudovaris, Thomas, Mannering, Stuart I., Elliott, Michael, Tangye, Stuart G., Wakim, Linda M., Rossjohn, Jamie

, Vijaykrishna, Dhanasekaran, Luciani, Fabio, Thomas, Paul G., Gras, Stephanie, Purcell, Anthony W. and Kedzierska, Katherine 2019. Human CD8+ T cell cross-reactivity across influenza A, B and C viruses. Nature Immunology 20 , pp. 613-625. 10.1038/s41590-019-0320-6

Dey, Shuvashis, Vaidyanathan, Ramanathan, Reza, K. Kamil, Wang, Jing, Wang, Yuling, Nel, Hendrik J., Law, Soi-Cheng, Tyler, Jennifer, Rossjohn, Jamie

, Reid, Hugh H., Ibn Sina, Abu Ali, Thomas, Ranjeny and Trau, Matt 2019. A microfluidic-SERSplatform for isolation and immuno-phenotyping of antigen specific T-cells. Sensors and Actuators B: Chemical 284 , pp. 281-288. 10.1016/j.snb.2018.12.099

Mayassi, Toufic, Ladell, Kristin

, Gudjonson, Herman, McLaren, James E.

, Shaw, Dustin G., Tran, Mai T., Rokicka, Jagoda J., Lawrence, Ian, Grenier, Jean-Christophe, van Unen, Vincent, Ciszewski, Cezary, Dimaano, Matthew, Sayegh, Hoda E., Kumar, Vinod, Wijmenga, Cisca, Green, Peter H.R., Gokhale, Ranjana, Jericho, Hilary, Semrad, Carol E., Guandalini, Stefano, Dinner, Aaron R., Kupfer, Sonia S., Reid, Hugh H., Barreiro, Luis B., Rossjohn, Jamie

, Price, David A.

and Jabri, Bana 2019. Chronic inflammation permanently reshapes tissue-resident immunity in celiac disease. Cell 176 (5) , 967-981.e19. 10.1016/j.cell.2018.12.039

Neier, Steven C., Ferrer, Alejandro, Wilton, Katelynn M., Smith, Stephen E. P., Kelcher, April M. H., Pavelko, Kevin D., Canfield, Jenna M., Davis, Tessa R., Stiles, Robert J., Chen, Zhenjun, McCluskey, James, Burrows, Scott R., Rossjohn, Jamie

, Hebrink, Deanne M., Carmona, Eva M., Limper, Andrew H., Kappes, Dietmar J., Wettstein, Peter J., Johnson, Aaron J., Pease, Larry R., Daniels, Mark A., Neuhauser, Claudia, Gil, Diana and Schrum, Adam G. 2019. The early proximal αβ TCR signalosome specifies thymic selection outcome through a quantitative protein interaction network. Science Immunology 4 (32) , eaal2201. 10.1126/sciimmunol.aal2201

Dahal-Koirala, Shiva, Ciacchi, Laura, Petersen, Jan, Risnes, Louise Fremgaard, Neumann, Ralf Stefan, Christophersen, Asbjørn, Lundin, Knut E. A., Reid, Hugh H., Qiao, Shuo-Wang, Rossjohn, Jamie

and Sollid, Ludvig M. 2019. Discriminative T-cell receptor recognition of highly homologous HLA-DQ2–bound gluten epitopes. Journal of Biological Chemistry 294 (3) , pp. 941-952. 10.1074/jbc.RA118.005736

Shahine, Adam, Reinink, Peter, Reijneveld, Josephine F., Gras, Stephanie, Holzheimer, Mira, Cheng, Tan-Yun, Minnaard, Adriaan J., Altman, John D., Lenz, Steffi, Prandi, Jacques, Kubler-Kielb, Joanna, Moody, D. Branch, Rossjohn, Jamie

and Van Rhijn, Ildiko 2019. A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids. Nature Communications 10 (1) , -. 10.1038/s41467-018-07898-0

Ooi, Joshua D., Jiang, Jhih-Hang, Eggenhuizen, Peter J., Chua, Ling L., van Timmeren, Mirjan, Loh, Khai L., O?Sullivan, Kim M., Gan, Poh Y., Zhong, Yong, Tsyganov, Kirill, Shochet, Lani R., Ryan, Jessica, Stegeman, Coen A., Fugger, Lars, Reid, Hugh H., Rossjohn, Jamie

, Heeringa, Peter, Holdsworth, Stephen R., Peleg, Anton Y. and Kitching, A. Richard 2019. A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity. Nature Communications 10 (1) , 3392. 10.1038/s41467-019-11255-0

Grant, Emma J., Josephs, Tracy M., Loh, Liyen, Clemens, E. Bridie, Sant, Sneha, Bharadwaj, Mandvi, Chen, Weisan, Rossjohn, Jamie

, Gras, Stephanie and Kedzierska, Katherine 2018. Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans. Nature Communications 9 (1) , -. 10.1038/s41467-018-07815-5

Gherardin, Nicholas A., McCluskey, James, Rossjohn, Jamie

and Godfrey, Dale I. 2018. The diverse family of MR1-restricted T cells. The Journal of Immunology 201 (10) , pp. 2862-2871. 10.4049/jimmunol.1801091

Illing, Patricia T., Pymm, Phillip, Croft, Nathan P., Hilton, Hugo G., Jojic, Vladimir, Han, Alex S., Mendoza, Juan L., Mifsud, Nicole A., Dudek, Nadine L., McCluskey, James, Parham, Peter, Rossjohn, Jamie

, Vivian, Julian P. and Purcell, Anthony W. 2018. HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome. Nature Communications 9 (1) , 4693. 10.1038/s41467-018-07109-w

Balaji, Gautham R., Aguilar, Oscar A., Tanaka, Miho, Shingu-Vazquez, Miguel A., Fu, Zhihui, Gully, Benjamin S., Lanier, Lewis L., Carlyle, James R., Rossjohn, Jamie

and Berry, Richard 2018. Recognition of host Clr-b by the inhibitory NKR-P1B receptor provides a basis for missing-self recognition. Nature Communications 9 (1) , 4623. 10.1038/s41467-018-06989-2

Faridi, Pouya, Li, Chen, Ramarathinam, Sri H., Vivian, Julian P., Illing, Patricia T., Mifsud, Nicole A., Ayala, Rochelle, Song, Jiangning, Gearing, Linden J., Hertzog, Paul J., Ternette, Nicola, Rossjohn, Jamie

, Croft, Nathan P. and Purcell, Anthony W. 2018. A subset of HLA-I peptides are not genomically templated: evidence for cis- and trans-spliced peptide ligands. Science Immunology 3 (28) , eaar3947. 10.1126/sciimmunol.aar3947

Robson, Kate J., Ooi, Joshua D., Holdsworth, Stephen R., Rossjohn, Jamie

and Kitching, A. Richard 2018. HLA and kidney disease: from associations to mechanisms. Nature Reviews Nephrology 14 (10) , pp. 636-655. 10.1038/s41581-018-0057-8

O'Donnell, Valerie

, Rossjohn, Jamie

and Wakelam, M. J. O. 2018. Phospholipid signaling in innate immune cells. The Journal of Clinical Investigation 128 (7) , pp. 2670-2679. 10.1172/JCI97944

Awad, Wael, Le Nours, Jérôme, Kjer-Nielsen, Lars, McCluskey, James and Rossjohn, Jamie

2018. Mucosal-associated invariant T cell receptor recognition of small molecules presented by MR1. Immunology and Cell Biology 96 (6) , pp. 588-597. 10.1111/imcb.12017

Kjer-Nielsen, Lars, Corbett, Alexandra J., Chen, Zhenjun, Liu, Ligong, Mak, Jeffrey Y. W., Godfrey, Dale I., Rossjohn, Jamie

, Fairlie, David P., McCluskey, James and Eckle, Sidonia B. G. 2018. An overview on the identification of MAIT cell antigens. Immunology and Cell Biology 96 (6) , pp. 573-587. 10.1111/imcb.12057

La Gruta, Nicole L., Gras, Stephanie, Daley, Stephen R., Thomas, Paul G. and Rossjohn, Jamie

2018. Understanding the drivers of MHC restriction of T cell receptors. Nature Reviews Immunology 18 , pp. 467-478. 10.1038/s41577-018-0007-5

Sant, Sneha, Grzelak, Ludivine, Wang, Zhongfang, Pizzolla, Angela, Koutsakos, Marios, Crowe, Jane, Loudovaris, Thomas, Mannering, Stuart I., Westall, Glen P., Wakim, Linda M., Rossjohn, Jamie

, Gras, Stephanie, Richards, Michael, Xu, Jianqing, Thomas, Paul G., Loh, Liyen, Nguyen, Thi H. O. and Kedzierska, Katherine 2018. Single-cell approach to influenza-specific CD8+ T Cell receptor repertoires across different age groups, tissues, and following influenza virus infection. Frontiers in Immunology 9 , 1453. 10.3389/fimmu.2018.01453

Rowntree, Louise C., Nguyen, Thi H. O., Halim, Hanim, Purcell, Anthony W., Rossjohn, Jamie

, Gras, Stephanie, Kotsimbos, Tom C. and Mifsud, Nicole A. 2018. Inability to detect cross-reactive memory T cells challenges the frequency of heterologous immunity among common viruses. Journal of Immunology 200 (12) , pp. 3993-4003. 10.4049/jimmunol.1800010

Galperin, Moran, Farenc, Carine, Mukhopadhyay, Madhura, Jayasinghe, Dhilshan, Decroos, Amandine, Benati, Daniela, Tan, Li Lynn, Ciacchi, Lisa, Reid, Hugh H., Rossjohn, Jamie

, Chakrabarti, Lisa A. and Gras, Stephanie 2018. CD4+ T cell–mediated HLA class II cross-restriction in HIV controllers. Science Immunology 3 (24) , eaat0687. 10.1126/sciimmunol.aat0687

Ramarathinam, Sri H., Gras, Stephanie, Alcantara, Sheilajen, Yeung, Amanda W.S., Mifsud, Nicole A., Sonza, Secondo, Illing, Patricia T., Glaros, Elias N., Center, Robert J., Thomas, Shane, Kent, Stephen J., Ternette, Nicola, Purcell, Damian F. J., Rossjohn, Jamie

and Purcell, Anthony W. 2018. Identification of native and post-translationally modified HLA-B*57:01-restricted HIV envelope derived epitopes using immunoproteomics. PROTEOMICS 18 (12) , 1700253. 10.1002/pmic.201700253

Cotton, Rachel N, Shahine, Adam, Rossjohn, Jamie

and Moody, D Branch 2018. Lipids hide or step aside for CD1-autoreactive T cell receptors. Current Opinion in Immunology 52 , pp. 93-99. 10.1016/j.coi.2018.04.013

Chennamadhavuni, Divya, Saavedra-Avila, Noemi Alejandra, Carreño, Leandro J., Guberman-Pfeffer, Matthew J., Arora, Pooja, Yongqing, Tang, Koay, Hui-Fern, Godfrey, Dale I., Keshipeddy, Santosh, Richardson, Stewart K., Sundararaj, Srinivasan, Lo, Jae Ho, Wen, Xiangshu, Gascón, José A., Yuan, Weiming, Rossjohn, Jamie

, Le Nours, Jérôme, Porcelli, Steven A. and Howell, Amy R. 2018. Dual modifications of α-Galactosylceramide Synergize to promote activation of human invariant natural killer T cells and stimulate anti-tumor immunity. Cell Chemical Biology 25 (5) , pp. 571-584. 10.1016/j.chembiol.2018.02.009

Dendrou, Calliope A., Petersen, Jan, Rossjohn, Jamie

and Fugger, Lars 2018. HLA variation and disease. Nature Reviews Immunology 18 , pp. 325-339. 10.1038/nri.2017.143

Varelias, Antiopi, Bunting, Mark D., Ormerod, Kate L., Koyama, Motoko, Olver, Stuart D., Straube, Jasmin, Kuns, Rachel D., Robb, Renee J., Henden, Andrea S., Cooper, Leanne, Lachner, Nancy, Gartlan, Kate H., Lantz, Olivier, Kjer-Nielsen, Lars, Mak, Jeffrey Y.W., Fairlie, David P., Clouston, Andrew D., McCluskey, James, Rossjohn, Jamie

, Lane, Steven W., Hugenholtz, Philip and Hill., Geoffrey R. 2018. Recipient mucosal-associated invariant T cells control GVHD within the colon. Journal of Clinical Investigation 128 (5) , pp. 1919-1936. 10.1172/JCI91646

Martin, Maureen P., Naranbhai, Vivek, Shea, Patrick R., Qi, Ying, Ramsuran, Veron, Vince, Nicolas, Gao, Xiaojiang, Thomas, Rasmi, Brumme, Zabrina L., Carlson, Jonathan M., Wolinsky, Steven M., Goedert, James J., Walker, Bruce D., Segal, Florencia P., Deeks, Steven G., Haas, David W., Migueles, Stephen A., Connors, Mark, Michael, Nelson, Fellay, Jacques, Gostick, Emma, Llewellyn-Lacey, Sian, Price, David A.

, Lafont, Bernard A., Pymm, Phillip, Saunders, Philippa M., Widjaja, Jacqueline, Wong, Shu Cheng, Vivian, Julian P., Rossjohn, Jamie

, Brooks, Andrew G. and Carrington, Mary 2018. Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1. Journal of Clinical Investigation 128 (5) , p. 1903. 10.1172/JCI98463

Wun, Kwok S., Reijneveld, Josephine F., Cheng, Tan-Yun, Ladell, Kristin

, Uldrich, Adam P., Le Nours, Jérôme, Miners, Kelly L., McLaren, James E.

, Grant, Emma J., Haigh, Oscar L., Watkins, Thomas S., Suliman, Sara, Iwany, Sarah, Jimenez, Judith, Calderon, Roger, Tamara, Kattya L., Leon, Segundo R., Murray, Megan B., Mayfield, Jacob A., Altman, John D., Purcell, Anthony W., Miles, John J., Godfrey, Dale I., Gras, Stephanie, Price, David A.

, Van Rhijn, Ildiko, Moody, D. Branch and Rossjohn, Jamie

2018. T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids. Nature Immunology 19 , pp. 397-406. 10.1038/s41590-018-0065-7

Miles, John J., Tan, Mai Ping, Dolton, Garry, Edwards, Emily S. J.

, Galloway, Sarah A. E., Laugel, Bruno, Clement, Mathew

, Makinde, Julia, Ladell, Kristin

, Matthews, Katherine K., Watkins, Thomas S., Tungatt, Katie, Wong, Yide, Lee, Han Siean, Clark, Richard J., Pentier, Johanne M., Attaf, Meriem, Lissina, Anya, Ager, Ann

, Gallimore, Awen

, Rizkallah, Pierre J.

, Gras, Stephanie, Rossjohn, Jamie

, Burrows, Scott R., Cole, David K.

, Price, David A.

and Sewell, Andrew K.

2018. Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry. Journal of Clinical Investigation 128 (4) , pp. 1569-1580. 10.1172/JCI91512

Godfrey, Dale I., Le Nours, Jérôme, Andrews, Daniel M., Uldrich, Adam P. and Rossjohn, Jamie

2018. Unconventional T cell targets for cancer immunotherapy. Immunity 48 (3) , pp. 453-473. 10.1016/j.immuni.2018.03.009

Chan, Kok Fei, Gully, Benjamin S., Gras, Stephanie, Beringer, Dennis X., Kjer-Nielsen, Lars, Cebon, Jonathan, McCluskey, James, Chen, Weisan and Rossjohn, Jamie

2018. Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide. Nature Communications 9 , 1026. 10.1038/s41467-018-03321-w

Ting, Yi Tian, Petersen, Jan, Ramarathinam, Sri H., Scally, Stephen W., Loh, Khai L., Thomas, Ranjeny, Suri, Anish, Baker, Daniel G., Purcell, Anthony W., Reid, Hugh H. and Rossjohn, Jamie

2018. The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis. Journal of Biological Chemistry 293 (9) , pp. 3236-3251. 10.1074/jbc.RA117.001013

D'Souza, Criselle, Pediongco, Troi, Wang, Huimeng, Scheerlinck, Jean-Pierre Y., Kostenko, Lyudmila, Esterbauer, Robyn, Stent, Andrew W., Eckle, Sidonia B. G., Meehan, Bronwyn S., Strugnell, Richard A., Cao, Hanwei, Liu, Ligong, Mak, Jeffrey Y. W., Lovrecz, George, Lu, Louis, Fairlie, David P., Rossjohn, Jamie

, McCluskey, James, Every, Alison L., Chen, Zhenjun and Corbett, Alexandra J. 2018. Mucosal-associated invariant T cells augment immunopathology and gastritis in chronic helicobacter pyloriInfection. The Journal of Immunology 200 (5) , pp. 1901-1916. 10.4049/jimmunol.1701512
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Sundararaj, Srinivasan, Zhang, Jingjing, Krovi, S. Harsha, Bedel, Romain, Tuttle, Kathryn D., Veerapen, Natacha, Besra, Gurdyal S., Khandokar, Yogesh, Praveena, T., Le Nours, Jérôme, Matsuda, Jennifer L., Rossjohn, Jamie

and Gapin, Laurent 2018. Differing roles of CD1d2 and CD1d1 proteins in type I natural killer T cell development and function. Proceedings of the National Academy of Sciences 115 (6) , E1204-E1213. 10.1073/pnas.1716669115

Jansen, Diahann T. S. L., Ramnoruth, Nishta, Loh, Khai L., Rossjohn, Jamie

, Reid, Hugh H., Nel, Hendrik J. and Thomas, Ranjeny 2018. Flow cytometric clinical immunomonitoring using peptide-MHC class II tetramers: optimization of methods and protocol development. Frontiers in Immunology 9 , 8. 10.3389/fimmu.2018.00008

Wang, Huimeng, D'Souza, Criselle, Lim, Xin Yi, Kostenko, Lyudmila, Pediongco, Troi J., Eckle, Sidonia B. G., Meehan, Bronwyn S., Shi, Mai, Wang, Nancy, Li, Shihan, Liu, Ligong, Mak, Jeffrey Y. W., Fairlie, David P., Iwakura, Yoichiro, Gunnersen, Jennifer M., Stent, Andrew W., Godfrey, Dale I., Rossjohn, Jamie

, Westall, Glen P., Kjer-Nielsen, Lars, Strugnell, Richard A., McCluskey, James, Corbett, Alexandra J., Hinks, Timothy S. C. and Chen, Zhenjun 2018. MAIT cells protect against pulmonary Legionella longbeachae infection. Nature Communications 9 (1) , 3350. 10.1038/s41467-018-05202-8

Sullivan, Lucy C., Walpole, Nicholas G., Farenc, Carine, Pietra, Gabriella, Sum, Matthew J. W., Clements, Craig S., Lee, Eleanor J., Beddoe, Travis, Falco, Michela, Mingari, Maria Cristina, Moretta, Lorenzo, Gras, Stephanie, Rossjohn, Jamie

and Brooks, Andrew G. 2017. A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct αβ T cell receptors. Journal of Biological Chemistry 292 (51) , pp. 21149-21158. 10.1074/jbc.M117.807719

Cook, Laura, Munier, C. Mee Ling, Seddiki, Nabila, van Bockel, David, Ontiveros, Noé, Hardy, Melinda Y., Gillies, Jana K., Levings, Megan K., Reid, Hugh H., Petersen, Jan, Rossjohn, Jamie

, Anderson, Robert P., Zaunders, John J., Tye-Din, Jason A. and Kelleher, Anthony D. 2017. Circulating gluten-specific FOXP3 + CD39 + regulatory T cells have impaired suppressive function in patients with celiac disease. Journal of Allergy and Clinical Immunology 140 (6) , pp. 1592-1603. 10.1016/j.jaci.2017.02.015

Van Braeckel-Budimir, Natalija, Gras, Stephanie, Ladell, Kristin

, Josephs, Tracy M., Pewe, Lecia, Urban, Stina L., Miners, Kelly L., Farenc, Carine, Price, David A.

, Rossjohn, Jamie

and Harty, John T. 2017. A T cell receptor locus harbors a malaria-specific immune response gene. Immunity 47 (5) , 835-847.e4. 10.1016/j.immuni.2017.10.013

Scally, Stephen W, Law, Soi-Cheng, Ting, Yi Tian, Heemst, Jurgen van, Sokolove, Jeremy, Deutsch, Aaron J, Bridie Clemens, E, Moustakas, Antonis K, Papadopoulos, George K, Woude, Diane van der, Smolik, Irene, Hitchon, Carol A, Robinson, David B, Ferucci, Elizabeth D, Bernstein, Charles N, Meng, Xiaobo, Anaparti, Vidyanand, Huizinga, Tom, Kedzierska, Katherine, Reid, Hugh H, Raychaudhuri, Soumya, Toes, René E, Rossjohn, Jamie

, El-Gabalawy, Hani and Thomas, Ranjeny 2017. Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis. Annals of the Rheumatic Diseases 76 (11) , pp. 1915-1923. 10.1136/annrheumdis-2017-211300

Culshaw, Abigail,

, ,

and

2017. Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8+ T cell response. Nature Immunology 18 , pp. 1228-1237. 10.1038/ni.3850

Shahine, Adam, Van Rhijn, Ildiko, Cheng, Tan-Yun, Iwany, Sarah, Gras, Stephanie, Moody, D. Branch and Rossjohn, Jamie

2017. A molecular basis of human T cell receptor autoreactivity toward self-phospholipids. Science Immunology 2 (16) , eaao1384. 10.1126/sciimmunol.aao1384

Mobbs, Jesse I., Illing, Patricia T., Dudek, Nadine L., Brooks, Andrew G., Baker, Daniel G., Purcell, Anthony W., Rossjohn, Jamie

and Vivian, Julian P. 2017. The molecular basis for peptide repertoire selection in the human leukocyte antigen (HLA) C*06:02 molecule. Journal of Biological Chemistry 292 (42) , pp. 17203-17215. 10.1074/jbc.M117.806976

Rouxel, Ophélie, Da silva, Jennifer, Beaudoin, Lucie, Nel, Isabelle, Tard, Céline, Cagninacci, Lucie, Kiaf, Badr, Oshima, Masaya, Diedisheim, Marc, Salou, Marion, Corbett, Alexandra, Rossjohn, Jamie

, McCluskey, James, Scharfmann, Raphael, Battaglia, Manuela, Polak, Michel, Lantz, Olivier, Beltrand, Jacques and Lehuen, Agnès 2017. Cytotoxic and regulatory roles of mucosal-associated invariant T cells in type 1 diabetes. Nature Immunology 18 (12) , pp. 1321-1331. 10.1038/ni.3854

Littler, Dene R., Ang, Sheng Y., Moriel, Danilo G., Kocan, Martina, Kleifeld, Oded, Johnson, Matthew D., Tran, Mai T., Paton, Adrienne W., Paton, James C., Summers, Roger J., Schembri, Mark A., Rossjohn, Jamie

and Beddoe, Travis 2017. Structure-function analyses of a pertussis-like toxin from pathogenic Escherichia coli reveal a distinct mechanism of inhibition of trimeric G-proteins. Journal of Biological Chemistry 292 (36) , pp. 15143-15158. 10.1074/jbc.M117.796094

Brennan, Patrick J., Cheng, Tan-Yun, Pellicci, Daniel G., Watts, Gerald F. M., Veerapen, Natacha, Young, David C., Rossjohn, Jamie

, Besra, Gurdyal S., Godfrey, Dale I., Brenner, Michael B. and Moody, D. Branch 2017. Structural determination of lipid antigens captured at the CD1d-T-cell receptor interface. Proceedings of the National Academy of Sciences of the United States of America 114 (31) , pp. 8348-8353. 10.1073/pnas.1705882114

Deuss, Felix A., Gully, Benjamin S., Rossjohn, Jamie

and Berry, Richard 2017. Recognition of nectin-2 by the natural killer cell receptor T cell immunoglobulin and ITIM domain (TIGIT). Journal of Biological Chemistry 292 (27) , pp. 11413-11422. 10.1074/jbc.M117.786483

Kaur, Gurman, Gras, Stephanie, Mobbs, Jesse I., Vivian, Julian P., Cortes, Adrian, Barber, Thomas, Kuttikkatte, Subita Balaram, Jensen, Lise Torp, Attfield, Kathrine E., Dendrou, Calliope A., Carrington, Mary, McVean, Gil, Purcell, Anthony W., Rossjohn, Jamie

and Fugger, Lars 2017. Structural and regulatory diversity shape HLA-C protein expression levels. Nature Communications 8 , p. 15924. 10.1038/ncomms15924

Shaler, Christopher R., Choi, Joshua, Rudak, Patrick T., Memarnejadian, Arash, Szabo, Peter A., Tun-Abraham, Mauro E., Rossjohn, Jamie

, Corbett, Alexandra J., McCluskey, James, McCormick, John K., Lantz, Olivier, Hernandez-Alejandro, Roberto and Haeryfar, S.M. Mansour 2017. MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate antimicrobial function: Defining a novel mechanism of superantigen-induced immunopathology and immunosuppression. PLoS Biology 15 (6) , e2001930. 10.1371/journal.pbio.2001930

Ooi, Joshua D., Petersen, Jan, Tan, Yu H., Huynh, Megan, Willett, Zoe J., Ramarathinam, Sri H., Eggenhuizen, Peter J., Loh, Khai L., Watson, Katherine A., Gan, Poh Y., Alikhan, Maliha A., Dudek, Nadine L., Handel, Andreas, Hudson, Billy G., Fugger, Lars, Power, David A., Holt, Stephen G., Coates, P. Toby, Gregersen, Jon W., Purcell, Anthony W., Holdsworth, Stephen R., La Gruta, Nicole L., Reid, Hugh H., Rossjohn, Jamie

and Kitching, A. Richard 2017. Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells. Nature 545 (7653) , pp. 243-247. 10.1038/nature22329

De Weerd, Nicola A., Matthews, Anthony Y., Pattie, Philip R., Bourke, Nollaig M., Lim, San S., Vivian, Julian P., Rossjohn, Jamie

and Hertzog, Paul J. 2017. A hot spot on interferon α/β receptor subunit 1 (IFNAR1) underpins its interaction with interferon-β and dictates signaling. World Journal of Biological Chemistry 292 , pp. 7554-7565. 10.1074/jbc.M116.773788

Keller, Andrew N., Eckle, Sidonia B. G., Xu, Weijun, Liu, Ligong, Hughes, Victoria A., Mak, Jeffrey Y. W., Meehan, Bronwyn S., Pediongco, Troi, Birkinshaw, Richard W., Chen, Zhenjun, Wang, Huimeng, D'Souza, Criselle, Kjer-Nielsen, Lars, Gherardin, Nicholas A., Godfrey, Dale I., Kostenko, Lyudmila, Corbett, Alexandra J., Purcell, Anthony W., Fairlie, David P., McCluskey, James and Rossjohn, Jamie

2017. Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells. Nature Immunology 18 , pp. 402-411. 10.1038/ni.3679

Pymm, Phillip, Illing, Patricia T., Ramarathinam, Sri H., O'Connor, Geraldine M., Hughes, Victoria A., Hitchen, Corinne, Price, David A.

, Ho, Bosco K., McVicar, Daniel W., Brooks, Andrew G., Purcell, Anthony W., Rossjohn, Jamie

and Vivian, Julian P. 2017. MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape. Nature Structural and Molecular Biology 24 , pp. 387-394. 10.1038/nsmb.3381

Aguilar, Oscar A., Berry, Richard, Rahim, Mir Munir A., Reichel, Johanna J., Popović, Branka, Tanaka, Miho, Fu, Zhihui, Balaji, Gautham R., Lau, Timothy N.H., Tu, Megan M., Kirkham, Christina L., Mahmoud, Ahmad Bakur, Mesci, Aruz, Krmpotić, Astrid, Allan, David S.J., Makrigiannis, Andrew P., Jonjić, Stipan, Rossjohn, Jamie

and Carlyle, James R. 2017. A viral immunoevasin controls innate immunity by targeting the prototypical natural killer cell receptor family. Cell 169 (1) , pp. 58-71. 10.1016/j.cell.2017.03.002

Mak, Jeffrey Y. W., Xu, Weijun, Reid, Robert C., Corbett, Alexandra J., Meehan, Bronwyn S., Wang, Huimeng, Chen, Zhenjun, Rossjohn, Jamie

, McCluskey, James, Liu, Ligong and Fairlie, David P. 2017. Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells. Nature Communications 8 , 14599. 10.1038/ncomms14599

Cheng, Janice M. H., Liu, Ligong, Pellicci, Daniel G., Reddiex, Scott J. J., Cotton, Rachel N., Cheng, Tan-Yun, Young, David C., Van Rhijn, Ildiko, Moody, D. Branch, Rossjohn, Jamie

, Fairlie, David P., Godfrey, Dale I. and Williams, Spencer J. 2017. Total synthesis of Mycobacterium tuberculosis dideoxymycobactin-838 and stereoisomers: diverse CD1a-restricted T cells display a common hierarchy of lipopeptide recognition. Chemistry - A European Journal 23 (7) , pp. 1694-1701. 10.1002/chem.201605287

Chen, Z., Wang, H., D'Souza, C., Sun, S., Kostenko, L., Eckle, S. B. G., Meehan, B. S., Jackson, D. C., Strugnell, R. A., Cao, H., Wang, N., Fairlie, D. P., Liu, L., Godfrey, D. I., Rossjohn, Jamie

, McCluskey, J. and Corbett, A. J. 2017. Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals. Mucosal Immunology 10 (1) , pp. 58-68. 10.1038/mi.2016.39

Littler, Dene R., Bullen, Hayley E., Harvey, Katherine L., Beddoe, Travis, Crabb, Brendan S., Rossjohn, Jamie

and Gilson, Paul R. 2016. Disrupting the allosteric interaction between the plasmodium falciparumcAMP-dependent kinase and its regulatory subunit. Journal of Biological Chemistry 291 (49) , p. 25375. 10.1074/jbc.M116.750174

Grant, Emma J., Josephs, Tracy M., Valkenburg, Sophie A., Wooldridge, Linda, Hellard, Margaret, Rossjohn, Jamie

, Bharadwaj, Mandvi, Kedzierska, Katherine and Gras, Stephanie 2016. Lack of heterologous cross-reactivity toward HLA-A*02:01 restricted viral epitopes is underpinned by distinct αβT cell receptor signatures. Journal of Biological Chemistry 291 (47) 10.1074/jbc.M116.753988

Pageon, Sophie V., Tabarin, Thibault, Yamamoto, Yui, Ma, Yuanqing, Nicovich, Philip R., Bridgeman, John S., Cohnen, Andre, Benzing, Carola, Gao, Yijun, Crowther, Michael D., Tungatt, Katie, Dolton, Garry, Sewell, Andrew K., Price, David A., Acuto, Oreste, Parton, Robert G., Gooding, J. Justin, Rossy, Jeremie, Rossjohn, Jamie

and Gaus, Katharina 2016. Correction for Pageon et al., functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination. Proceedings of the National Academy of Sciences 113 (44) , E6905-E6905. 10.1073/pnas.1615763113

De Weerd, N. A., Matthews, A., Lim, S. S., Pattie, P., Bourke, N., Vivian, J. P., Rossjohn, Jamie

and Hertzog, P. J. 2016. P140: Understanding the IFNÂ-IFNAR1 interface: implications for drug discovery in IFNÂ-DRIVEN disease [Poster Abstract]. Cytokine 87 , p. 120. 10.1016/j.cyto.2016.07.021

Koay, Hui-Fern, Gherardin, Nicholas A., Enders, Anselm, Loh, Liyen, Mackay, Laura K., Almeida, Catarina F., Russ, Brendan E., Nold-Petry, Claudia A., Nold, Marcel F., Bedoui, Sammy, Chen, Zhenjun, Corbett, Alexandra J., Eckle, Sidonia B. G., Meehan, Bronwyn, d'Udekem, Yves, Konstantinov, Igor E., Lappas, Martha, Liu, Ligong, Goodnow, Chris C., Fairlie, David P., Rossjohn, Jamie

, Chong, Mark M., Kedzierska, Katherine, Berzins, Stuart P., Belz, Gabrielle T., McCluskey, James, Uldrich, Adam P., Godfrey, Dale I. and Pellicci, Daniel G. 2016. A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage. Nature Immunology 17 (11) , pp. 1300-1311. 10.1038/ni.3565

Gras, Stephanie, Van Rhijn, Ildiko, Shahine, Adam, Cheng, Tan-Yun, Bhati, Mugdha, Tan, Li Lynn, Halim, Hanim, Tuttle, Kathryn D., Gapin, Laurent, Le Nours, Jerome, Moody, D. Branch and Rossjohn, Jamie

2016. T cell receptor recognition of CD1b presenting a mycobacterial glycolipid. Nature Communications 7 , 13257. 10.1038/ncomms13257

Jaafar, Nardiah Rizwana, Littler, Dene, Beddoe, Travis, Rossjohn, Jamie

, Illias, Rosli Md, Mahadi, Nor Muhammad, Mackeen, Mukram Mohamed, Murad, Abdul Munir Abdul and Abu Bakar, Farah Diba 2016. Crystal structure of fuculose aldolase from the Antarctic psychrophilic yeastGlaciozyma antarctica PI12. Acta Crystallographica Section F Structural Biology Communications 72 (11) , pp. 831-839. 10.1107/S2053230X16015612

Gras, Stephanie, Chadderton, Jesseka, Del Campo, Claudia M., Farenc, Carine, Wiede, Florian, Josephs, Tracy M., Sng, Xavier Y. X., Mirams, Michiko, Watson, Katherine A., Tiganis, Tony, Quinn, Kylie M., Rossjohn, Jamie

and La Gruta, Nicole L. 2016. Reversed T cell receptor docking on a major histocompatibility class I complex limits involvement in the immune response. Immunity 45 (4) , pp. 749-760. 10.1016/j.immuni.2016.09.007

Petersen, Jan, Kooy-Winkelaar, Yvonne, Loh, Khai Lee, Tran, Mai, van Bergen, Jeroen, Koning, Frits, Rossjohn, Jamie

and Reid, Hugh H. 2016. Diverse T cell receptor gene usage in HLA-DQ8-associated celiac disease converges into a consensus binding solution. Structure 24 (10) , pp. 1643-1657. 10.1016/j.str.2016.07.010

Kim, Ji Hyung, Hu, Yu, Yongqing, Tang, Kim, Jessica, Hughes, Victoria A., Le Nours, Jerome, Marquez, Elsa A., Purcell, Anthony W., Wan, Qi, Sugita, Masahiko, Rossjohn, Jamie

and Winau, Florian 2016. CD1a on Langerhans cells controls inflammatory skin disease. Nature Immunology 17 (10) , pp. 1159-1166. 10.1038/ni.3523

Pageon, Sophie V., Tabarin, Thibault, Yamamoto, Yui, Ma, Yuanqing, Bridgeman, John S, Cohnen, André, Benzing, Carola, Gao, Yijun, Crowther, Michael D, Tungatt, Katie, Dolton, Garry, Sewell, Andrew

, Price, David A

, Acuto, Oreste, Parton, Robert G., Gooding, J. Justin, Rossy, Jérémie, Rossjohn, Jamie

and Gaus, Katharina 2016. Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination. Proceedings of the National Academy of Sciences 113 (37) , E5454-E5463. 10.1073/pnas.1607436113

Loh, Liyen, Wang, Zhongfang, Sant, Sneha, Koutsakos, Marios, Jegaskanda, Sinthujan, Corbett, Alexandra J., Liu, Ligong, Fairlie, David P., Crowe, Jane, Rossjohn, Jamie

, Xu, Jianqing, Doherty, Peter C., McCluskey, James and Kedzierska, Katherine 2016. Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18–dependent activation. Proceedings of the National Academy of Sciences 113 (36) , pp. 10133-10138. 10.1073/pnas.1610750113

Sullivan, Lucy C., Berry, Richard, Sosnin, Natasha, Widjaja, Jacqueline M. L., Deuss, Felix A., Balaji, Gautham R., LaGruta, Nicole L., Mirams, Michiko, Trapani, Joseph A., Rossjohn, Jamie

, Brooks, Andrew G. and Andrews, Daniel M. 2016. Recognition of the Major Histocompatibility Complex (MHC) class Ib molecule H2-Q10 by the natural killer cell receptor Ly49C. Journal of Biological Chemistry 291 (36) , pp. 18740-18752. 10.1074/jbc.M116.737130

Cole, David K.

, Bulek, Anna M., Dolton, Garry, Schauenberg, Andrea J., Szomolay, Barbara

, Rittase, William, Trimby, Andrew, Jothikumar, Prithiviraj, Fuller, Anna, Skowera, Ania, Rossjohn, Jamie

, Zhu, Cheng, Miles, John J., Peakman, Mark, Wooldridge, Linda, Rizkallah, Pierre J.

and Sewell, Andrew K.

2016. Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. Journal of Clinical Investigation 126 (6) , pp. 2191-2204. 10.1172/JCI85679

Jönsson, Peter, Southcombe, Jennifer H., Santos, Ana Mafalda, Huo, Jiandong, Fernandes, Ricardo A., McColl, James, Lever, Melissa, Evans, Edward J., Hudson, Alexander, Chang, Veronica T., Hanke, Tomá?, Godkin, Andrew

, Dunne, Paul D., Horrocks, Mathew H., Palayret, Matthieu, Screaton, Gavin R., Petersen, Jan, Rossjohn, Jamie

, Fugger, Lars, Dushek, Omer, Xu, Xiao-Ning, Davis, Simon J. and Klenerman, David 2016. Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions. Proceedings of the National Academy of Sciences of the United States of America 113 (20) , pp. 5682-5687. 10.1073/pnas.1513918113

Vinton, Carol, Wu, Fan, Rossjohn, Jamie

, Matsuda, Kenta, McCluskey, James, Hirsch, Vanessa, Price, David

, Brenchley, Jason M. and Silvestri, G. 2016. Mucosa-associated invariant T cells are systemically depleted in simian immunodeficiency virus-infected rhesus macaques. Journal of Virology 90 (9) , pp. 4520-4529. 10.1128/JVI.02876-15

Benati, Daniela, Galperin, Moran, Lambotte, Olivier, Gras, Stéphanie, Lim, Annick, Mukhopadhyay, Madhura, Nouël, Alexandre, Campbell, Kristy-Anne, Lemercier, Brigitte, Claireaux, Mathieu, Hendou, Samia, Lechat, Pierre, de Truchis, Pierre, Boufassa, Faroudy, Rossjohn, Jamie

, Delfraissy, Jean-François, Arenzana-Seisdedos, Fernando and Chakrabarti, Lisa A. 2016. Public T cell receptors confer high-avidity CD4 responses to HIV controllers. The Journal of Clinical Investigation 126 (6) , pp. 2093-2108. 10.1172/JCI83792

Valkenburg, Sophie A., Josephs, Tracy M., Clemens, E. Bridie, Grant, Emma J., Nguyen, Thi H. O., Wang, George C., Price, David

, Miller, Adrian, Tong, Steven Y. C., Thomas, Paul G., Doherty, Peter C., Rossjohn, Jamie

, Gras, Stephanie and Kedzierska, Katherine 2016. Molecular basis for universal HLA-A*0201 - restricted CD8+ T-cell immunity against influenza viruses. Proceedings of the National Academy of Sciences of the United States of America 113 (16) , pp. 4440-4445. 10.1073/pnas.1603106113

Du, V. Y., Bansal, A., Carlson, J., Salazar-Gonzalez, J. F., Salazar, M. G., Ladell, Kristin Ingrid

, Gras, S., Josephs, T. M., Heath, S. L., Price, David

, Rossjohn, Jamie

, Hunter, E. and Goepfert, P. A. 2016. HIV-1-specific CD8 T cells exhibit limited cross-reactivity during acute infection. The Journal of Immunology 196 (8) , pp. 3276-3286. 10.4049/jimmunol.1502411

Saunders, Philippa M., Pymm, Phillip, Pietra, Gabriella, Hughes, Victoria A., Hitchen, Corinne, O?Connor, Geraldine M., Loiacono, Fabrizio, Widjaja, Jacqueline, Price, David

, Falco, Michela, Mingari, Maria Cristina, Moretta, Lorenzo, McVicar, Daniel W., Rossjohn, Jamie

, Brooks, Andrew G. and Vivian, Julian P. 2016. Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition. Journal of Experimental Medicine 213 (5) , pp. 791-807. 10.1084/jem.20152023

McWilliam, Hamish E G, Eckle, Sidonia B G, Theodossis, Alex, Liu, Ligong, Chen, Zhenjun, Wubben, Jacinta M, Fairlie, David P, Strugnell, Richard A, Mintern, Justine D, McCluskey, James, Rossjohn, Jamie

and Villadangos, Jose A 2016. The intracellular pathway for the presentation of vitamin B-related antigens by the antigen-presenting molecule MR1. Nature Immunology 10.1038/ni.3416

Rossjohn, Jamie

and Koning, F. 2016. A biased view toward celiac disease. Mucosal Immunology 9 (3) , pp. 583-586. 10.1038/mi.2016.17

Le Nours, Jérôme, Praveena, T., Pellicci, Daniel G., Gherardin, Nicholas A., Ross, Fiona J., Lim, Ricky T., Besra, Gurdyal S., Keshipeddy, Santosh, Richardson, Stewart K., Howell, Amy R., Gras, Stephanie, Godfrey, Dale I., Rossjohn, Jamie

and Uldrich, Adam P. 2016. Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens. Nature Communications 7 , 10570. 10.1038/ncomms10570

Gherardin, Nicholas A., Keller, Andrew N., Woolley, Rachel E., Le Nours, Jérôme, Ritchie, David S., Neeson, Paul J., Birkinshaw, Richard W., Eckle, Sidonia B.G., Waddington, John N., Liu, Ligong, Fairlie, David P., Uldrich, Adam P., Pellicci, Daniel G., McCluskey, James, Godfrey, Dale I. and Rossjohn, Jamie

2016. Diversity of T cells restricted by the MHC class I-related molecule MR1 facilitates differential antigen recognition. Immunity 44 (1) , pp. 32-45. 10.1016/j.immuni.2015.12.005

Koay, Hui Fern, Gherardin, Nicholas A., Enders, Anselm, Loh, Liyen, Chen, Zhenjun, Corbett, Alexandra J., Eckle, Siodonia B. G., Meehan, Bronwyn, d’Udekem, Yves, Konstantinov, Igor, Lappas, Martha, Liu, Ligong, Goodnow, Chris C., Fairlie, David P., Rossjohn, Jamie

, Kedzirska, Katherine, Berzins, Stuart P., McCluskey, James, Uldrich, Adam P., Godfrey, Dale I. and Peellicci, Daniel G. 2016. Thymic precursors to the Mucosal-Associated Invariant T cell lineage. European Journal of Immunology 46 (1) , p. 256. 10.1002/eji.201670015

Beringer, Dennis X., Kleijwegt, Fleur S., Wiede, Florian, van der Slik, Arno R., Loh, Khai Lee, Petersen, Jan, Dudek, Nadine L., Duinkerken, Gaby, Laban, Sandra, Joosten, Antoinette, Vivian, Julian P., Chen, Zhenjun, Uldrich, Adam P., Godfrey, Dale I., McCluskey, James, Price, David A.

, Radford, Kristen J., Purcell, Anthony W., Nikolic, Tatjana, Reid, Hugh H., Tiganis, Tony, Roep, Bart O. and Rossjohn, Jamie

2015. T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex. Nature Immunology 16 , pp. 1153-1161. 10.1038/ni.3271

Clemens, E Bridie, Grant, Emma J, Wang, Zhongfang, Gras, Stephanie, Tipping, Peta, Rossjohn, Jamie

, Miller, Adrian, Tong, Steven YC and Kedzierska, Katherine 2015. Towards identification of immune and genetic correlates of severe influenza disease in Indigenous Australians. Immunology and Cell Biology 94 (4) , pp. 367-377. 10.1038/icb.2015.93

Gartlan, K. H., Markey, K. A., Varelias, A., Bunting, M. D., Koyama, M., Kuns, R. D., Raffelt, N. C., Olver, S. D., Lineburg, K. E., Cheong, M., Teal, B. E., Lor, M., Comerford, I., Teng, M. W. L., Smyth, M. J., McCluskey, J., Rossjohn, Jamie

, Stockinger, B., Boyle, G. M., Lane, S. W., Clouston, A. D., McColl, S. R., MacDonald, K. P. A. and Hill, G. R. 2015. Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8+ T cells that induce GVHD without antileukemic effects. Blood 126 (13) , pp. 1609-1620. 10.1182/blood-2015-01-622662

Saunders, Philippa M., Vivian, Julian P., O'Connor, Geraldine M., Sullivan, Lucy C., Pymm, Phillip, Rossjohn, Jamie

and Brooks, Andrew G. 2015. A bird's eye view of NK cell receptor interactions with their MHC class I ligands. Immunological Reviews 267 (1) , pp. 148-166. 10.1111/imr.12319

Petersen, J., van Bergen, J., Loh, K. L., Kooy-Winkelaar, Y., Beringer, D. X., Thompson, A., Bakker, S. F., Mulder, C. J. J., Ladell, Kristin

, McLaren, James Edward

, Price, David

, Rossjohn, Jamie

, Reid, H. H. and Koning, F. 2015. Determinants of gliadin-specific T cell selection in celiac disease. The Journal of Immunology 194 (12) , pp. 6112-6122. 10.4049/jimmunol.1500161

McWilliam, Hamish EG, Birkinshaw, Richard W, Villadangos, Jose A, McCluskey, James and Rossjohn, Jamie

2015. MR1 presentation of vitamin B-based metabolite ligands. Current Opinion in Immunology 34 , pp. 28-34. 10.1016/j.coi.2014.12.004

Rist, M. J., Hibbert, K. M., Croft, N. P., Smith, C., Neller, M. A., Burrows, J. M., Miles, John James, Purcell, A. W., Rossjohn, Jamie

, Gras, S. and Burrows, S. R. 2015. T cell cross-reactivity between a highly immunogenic EBV epitope and a self-peptide naturally presented by HLA-B*18:01+ cells. The Journal of Immunology 194 (10) , pp. 4668-4675. 10.4049/jimmunol.1500233

O'Connor, Geraldine M., Vivian, Julian P., Gostick, Emma, Pymm, Phillip, Lafont, Bernard A. P., Price, David

, Rossjohn, Jamie

, Brooks, Andrew G., McVicar, Daniel W. and Kirchhoff, F. 2015. Peptide-dependent recognition of HLA-B*57:01 by KIR3DS1. Journal of Virology 89 (10) , pp. 5213-5221. 10.1128/JVI.03586-14

Magalhaes, Isabelle, Pingris, Karine, Poitou, Christine, Bessoles, Stéphanie, Venteclef, Nicolas, Kiaf, Badr, Beaudoin, Lucie, Da Silva, Jennifer, Allatif, Omran, Rossjohn, Jamie

, Kjer-Nielsen, Lars, McCluskey, James, Ledoux, Séverine, Genser, Laurent, Torcivia, Adriana, Soudais, Claire, Lantz, Olivier, Boitard, Christian, Aron-Wisnewsky, Judith, Larger, Etienne, Clément, Karine and Lehuen, Agnès 2015. Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients. The Journal of Clinical Investigation 125 (4) , pp. 1752-1762. 10.1172/JCI78941

Birkinshaw, Richard W., Pellicci, Daniel G., Cheng, Tan-Yun, Keller, Andrew N., Sandoval-Romero, Maria, Gras, Stephanie, de Jong, Annemieke, Uldrich, Adam P., Moody, D. Branch, Godfrey, Dale I. and Rossjohn, Jamie

2015. αβ T cell antigen receptor recognition of CD1a presenting self lipid ligands. Nature Immunology 16 , pp. 258-266. 10.1038/ni.3098

Moradi, Shoeib, Berry, Richard, Pymm, Phillip, Hitchen, Corinne, Beckham, Simone A., Wilce, Matthew C.J., Walpole, Nicholas G., Clements, Craig S., Reid, Hugh H., Perugini, Matthew A., Brooks, Andrew G., Rossjohn, Jamie

and Vivian, Julian P. 2015. The structure of the atypical killer cell immunoglobulin-like receptor, KIR2DL4. The Journal of Biological Chemistry 10.1074/jbc.M114.612291

Rossjohn, Jamie

, Gras, Stephanie, Miles, John James, Turner, Stephen J., Godfrey, Dale I. and McCluskey, James 2015. T cell antigen receptor recognition of antigen-presenting molecules. Annual Review of Immunology 33 (1) , pp. 169-200. 10.1146/annurev-immunol-032414-112334

Miles, John James, McCluskey, James, Rossjohn, Jamie

and Gras, Stephanie 2015. Understanding the complexity and malleability of T-cell recognition. Immunology and Cell Biology 93 (5) , pp. 433-441. 10.1038/icb.2014.112

Saunders, P. M., Vivian, J. P., Baschuk, N., Beddoe, T., Widjaja, J., O'Connor, G. M., Hitchen, C., Pymm, P., Andrews, D. M., Gras, S., McVicar, D. W., Rossjohn, Jamie

and Brooks, A. G. 2015. The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope. The Journal of Immunology 194 (2) , pp. 781-789. 10.4049/jimmunol.1402542

Hassan, Chopie, Chabrol, Eric, Jahn, Lorenz, Kester, Michel G.D., de Ru, Arnoud H., Drijfhout, Jan W., Rossjohn, Jamie

, Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M., Gras, Stephanie and van Veelen, Peter A. 2014. Naturally processed non-canonical HLA-A*02:01 presented peptides. The Journal of Biological Chemistry 290 (5) , pp. 2593-2603. 10.1074/jbc.M114.607028

Nivarthi, Usha K., Gras, Stephanie, Kjer-Nielsen, Lars, Berry, Richard, Lucet, Isabelle S., Miles, John J., Tracy, Samantha L., Purcell, Anthony W., Bowden, David S., Hellard, Margaret, Rossjohn, Jamie

, McCluskey, James and Bharadwaj, Mandvi 2014. An extensive antigenic footprint underpins immunodominant TCR adaptability against a hypervariable viral determinant. The Journal of Immunology 193 (11) , pp. 5402-5413. 10.4049/jimmunol.1401357

Birnbaum, Michael E., Berry, Richard, Hsiao, Yu-Shan, Chen, Zhenjun, Shingu-Vazquez, Miguel A., Yu, Xiaoling, Waghray, Deepa, Fischer, Suzanne, McCluskey, James, Rossjohn, Jamie

, Walz, Thomas and Garcia, K. Christopher 2014. Molecular architecture of the αβ T cell receptor–CD3 complex. Proceedings of the National Academy of Sciences of the United States of America 111 (49) , pp. 17576-17581. 10.1073/pnas.1420936111

Fernandez, Caroline S., Amarasena, Thakshila, Kelleher, Anthony D., Rossjohn, Jamie

, McClusky, James, Godfrey, Dale I. and Kent, Stephen J. 2014. MAIT cells are depleted early but retain functional cytokine expression in HIV infection. Immunology and Cell Biology 93 (2) , pp. 177-188. 10.1038/icb.2014.91

Trujillo, Jonathan A., Croft, Nathan P., Dudek, Nadine L., Channappanavar, Rudragouda, Theodossis, Alex, Webb, Andrew I., Dunstone, Michelle A., Illing, Patricia T., Butler, Noah S., Fett, Craig, Tscharke, David C., Rossjohn, Jamie

, Perlman, Stanley and Purcell, Anthony W. 2014. The cellular redox environment alters antigen presentation. The Journal of Biological Chemistry 289 (40) , pp. 27979-91. 10.1074/jbc.M114.573402

Berry, Richard, Vivian, Julian P., Deuss, Felix A., Balaji, Gautham R., Saunders, Philipa M., Lin, Jie, Littler, Dene R., Brooks, Andrew G. and Rossjohn, Jamie

2014. The structure of the cytomegalovirus-encoded m04 glycoprotein, a prototypical member of the m02 family of immunoevasins. The Journal of Biological Chemistry 289 (34) , pp. 23753-23763. 10.1074/jbc.M114.584128

Trujillo, Jonathan A., Gras, Stephanie, Twist, Kelly-Anne, Croft, Nathan P., Channappanavar, Rudragouda, Rossjohn, Jamie

, Purcell, Anthony W. and Perlman, Stanley 2014. Structural and functional correlates of enhanced antiviral immunity generated by heteroclitic CD8 T cell epitopes. The Journal of Immunology 192 (11) , pp. 5245-5256. 10.4049/jimmunol.1400111

Van Rhijn, Ildiko, Gherardin, Nicholas A., Kasmar, Anne, de Jager, Wilco, Pellicci, Daniel G., Kostenko, Lyudmila, Tan, Li Lynn, Bhati, Mugdha, Gras, Stephanie, Godfrey, Dale I., Rossjohn, Jamie

and Moody, D. Branch 2014. TCR bias and affinity define two compartments of the CD1b-glycolipid-specific T cell repertoire. Journal of Immunology 192 (9) , pp. 4054-4060. 10.4049/jimmunol.1400158

Petersen, Jan, Montserrat, Veronica, Mujico, Jorge R., Loh, Khai Lee, Beringer, Dennis X., van Lummel, Menno, Thompson, Allan, Mearin, M Luisa, Schweizer, Joachim, Kooy-Winkelaar, Yvonne, van Bergen, Jeroen, Drijfhout, Jan W., Kan, Wan-Ting, La Gruta, Nicole L, Anderson, Robert P., Reid, Hugh H., Koning, Frits and Rossjohn, Jamie

2014. T-cell receptor recognition of HLA-DQ2–gliadin complexes associated with celiac disease. Nature Structural and Molecular Biology 21 (5) , pp. 480-488. 10.1038/nsmb.2817

Liu, Yu Chih, Chen, Zhenjun, Neller, Michelle A., Miles, John J,, Purcell, Anthony W., McCluskey, James, Burrows, Scott R., Rossjohn, Jamie

and Gras, Stephanie 2014. A molecular basis for the interplay between T cells, viral mutants and human leukocyte antigen micropolymorphism. The Journal of Biological Chemistry 289 (24) , pp. 16688-98. 10.1074/jbc.M114.563502

Corbett, Alexandra J., Eckle, Sidonia B.G., Birkinshaw, Richard W., Liu, Ligong, Patel, Onisha, Mahony, Jennifer, Chen, Zhenjun, Reantragoon, Rangsima, Meehan, Bronwyn, Cao, Hanwei, Williamson, Nicholas A., Strugnell, Richard A., Van Sinderen, Douwe, Mak, Jeffrey Y.W., Fairlie, David P., Kjer-Nielsen, Lars, Rossjohn, Jamie

and McCluskey, James 2014. T-cell activation by transitory neo-antigens derived from distinct microbial pathways. Nature 509 (7500) , pp. 361-365. 10.1038/nature13160

O'Connor, G.eraldine M., Vivian, Julian P., Widjaja, Jacqueline M., Bridgeman, John S., Gostick, Emma, Lafont, Bernard A. P., Anderson, Stephen K., Price, David A.

, Brooks, Andrew G., Rossjohn, Jamie

and McVicar, Daniel W. 2014. Mutational and structural analysis of KIR3DL1 reveals a lineage-defining allotypic dimorphism that impacts both HLA and peptide sensitivity. Journal of Immunology 192 (6) , pp. 2875-2884. 10.4049/jimmunol.1303142

Bhati, Mugdha, Cole, David

, McCluskey, James, Sewell, Andrew K.

and Rossjohn, Jamie

2014. The versatility of the αβ T-cell antigen receptor. Protein Science 23 (3) , pp. 260-272. 10.1002/pro.2412

Berry, Richard, Rossjohn, Jamie

and Brooks, Andrew G. 2014. The Ly49 natural killer cell receptors: a versatile tool for viral self-discrimination. Immunology and Cell Biology 92 , pp. 214-220. 10.1038/icb.2013.100

Smith, Corey, Gras, Stephanie, Brennan, Rebekah M., Bird, Nicola L., Valkenburg, Sophie A., Twist, Kelly-Anne, Burrows, Jacqueline M., Miles, John James, Chambers, Daniel, Bell, Scott, Campbell, Scott, Kedzierska, Katherine, Burrows, Scott R, Rossjohn, Jamie

and Khanna, Rajiv 2014. Molecular imprint of exposure to naturally occurring genetic variants of human cytomegalovirus on the T cell repertoire. Scientific Reports 4 , 3993. 10.1038/srep03993

Stifter, Sebastian A., Gould, Jodee A., Mangan, Niamh E., Reid, Hugh H., Rossjohn, Jamie

, Hertzog, Paul J. and de Weerd, Nicole A. 2014. Purification and biological characterization of soluble, recombinant mouse IFNβ expressed in insect cells. Protein Expression and Purification 94 , pp. 7-14. 10.1016/j.pep.2013.10.019

Berry, Richard, Headey, Stephen J., Call, Melissa J., McCluskey, James, Tregaskes, Clive A., Kaufman, Jim, Koh, Ruide, Scanlon, Martin J., Call, Matthew E. and Rossjohn, Jamie

2014. Structure of the chicken CD3εδ/γ heterodimer and its assembly with the αβT cell receptor. The Journal of Biological Chemistry 289 (12) , pp. 8240-8251. 10.1074/jbc.M113.544965

Quiñones-Parraa, Sergio, Grant, Emma, Loha, Liyen, Nguyena, Thi H. O., Campbell, Kirsty-Anne, Tong, Steven Y. C., Miller, Adrian, Doherty, Peter C., Vijaykrishnag, Dhanasekaran, Rossjohn, Jamie

, Gras, Stephanie and Kedzierskaa, Katherine 2014. Preexisting CD8+ T-cell immunity to the H7N9 influenza A virus varies across ethnicities. Proceedings of the National Academy of Sciences of the United States of America 111 (3) , pp. 1049-1054. 10.1073/pnas.1322229111

Ng, Natasha M., Littler, Dene R., Paton, Adrienne W., Le Nours, Jérôme, Rossjohn, Jamie

, Paton, James C. and Beddoe, Travis 2013. EcxAB is a founding member of a new family of metalloprotease AB5 toxins with a hybrid cholera-like B subunit. Structure 21 (11) , pp. 2003-2013. 10.1016/j.str.2013.08.024

Kasmar, A. G., Van Rhijn, I., Magalhaes, K. G., Young, D. C., Cheng, T.-Y., Turner, M. T., Schiefner, A., Kalathur, R. C., Wilson, I. A., Bhati, M., Gras, S., Birkinshaw, R. W., Tan, L. L., Rossjohn, Jamie

, Shires, J., Jakobsen, S., Altman, J. D. and Moody, D. B. 2013. Cutting edge: CD1a tetramers and dextramers identify human lipopeptide-specific T cells ex vivo. The Journal of Immunology 191 (9) , pp. 4499-4503. 10.4049/jimmunol.1301660

Scally, S., Petersen, J., Law, S., Dudek, N., Nel, H., Loh, K., Wijeyewickrema, L., Eckle, S., van Heemst, J., Pike, R., McCluskey, J., Toes, R., La Gruta, N., Purcell, A., Reid, H., Thomas, R. and Rossjohn, Jamie

2013. A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis. Journal of Experimental Medicine 210 (12) , pp. 2569-2582. 10.1084/jem.20131241

Valkenburg, S., Quiñones-Parra, S., Gras, S., Komadina, N., McVernon, J., Wang, Z., Halim, H., Iannello, P., Cole, C., Laurie, K., Kelso, A., Rossjohn, Jamie

, Doherty, P., Turner, S. and Kedzierska, K. 2013. Acute emergence and reversion of influenza A virus quasispecies within CD8+ T cell antigenic peptides. Nature Communications 4 (3663) 10.1038/ncomms3663

Eckle, S. B., Turner, S. J., Rossjohn, Jamie

and McCluskey, J. 2013. Predisposed αβ T cell antigen receptor recognition of MHC and MHC-I like molecules? Current Opinion in Immunology 25 (5) , pp. 653-659. 10.1016/j.coi.2013.07.010

Le Nours, J., Paton, A., Byres, E., Troy, S., Herdman, B., Johnson, M., Paton, J., Rossjohn, Jamie

and Beddoe, T. 2013. Structural basis of subtilase cytotoxin subAB assembly. Journal of Biological Chemistry 288 (38) , pp. 27505-27516. 10.1074/jbc.M113.462622

de Weerd, N., Vivian, J., Nguyen, T., Mangan, N., Gould, J., Braniff, S., Zaker-Tabrizi, L., Fung, K., Forster, S., Beddoe, T., Reid, H., Rossjohn, Jamie

and Hertzog, P. 2013. Structural basis of a unique interferon-? signaling axis mediated via the receptor IFNAR1. Nature Immunology 14 (9) , pp. 901-907. 10.1038/ni.2667

Ng, N., Littler, D., Le Nours, J., Paton, A., Paton, J., Rossjohn, Jamie

and Beddoe, T. 2013. Cloning, expression, purification and preliminary X-ray diffraction studies of a novel AB5toxin. Acta Crystallographica Section F: Structural Biology and Crystallization Communications 69 (8) , pp. 912-915. 10.1107/S1744309113018927

Patel, O., Kjer-Nielsen, L., Le Nours, J., Eckle, S., Birkinshaw, R., Beddoe, T., Corbett, A., Liu, L., Miles, John James, Meehan, B., Reantragoon, R., Sandoval-Romero, M., Sullivan, L., Brooks, A., Chen, Z., Fairlie, D., McCluskey, J. and Rossjohn, Jamie

2013. Recognition of vitamin B metabolites by mucosal-associated invariant T cells. Nature Communications 4 (2142) 10.1038/ncomms3142

Rist, M. J., Theodossis, A., Croft, N. P., Neller, M. A., Welland, A., Chen, Z., Sullivan, L. C., Burrows, J. M., Miles, John James, Brennan, R. M., Gras, S., Khanna, R., Brooks, A. G., McCluskey, J., Purcell, A. W., Rossjohn, Jamie

and Burrows, S. R. 2013. HLA peptide length preferences control CD8+ T cell responses. The Journal of Immunology 191 (2) , pp. 561-571. 10.4049/jimmunol.1300292

Van Rhijn, I., Kasmar, A., de Jong, A., Gras, S., Bhati, M., Doorenspleet, M., de Vries, N., Godfrey, D., Altman, J., de Jager, W., Rossjohn, Jamie

and Moody, D. 2013. A conserved human T cell population targets mycobacterial antigens presented by CD1b. Nature Immunology 14 (7) , pp. 706-713. 10.1038/ni.2630

Liu, Y., Miles, John James, Neller, M., Gostick, E., Price, David

, Purcell, A., McCluskey, J., Burrows, S., Rossjohn, Jamie

and Gras, S. 2013. Highly divergent T-cell receptor binding modes underlie specific recognition of a bulged viral peptide bound to a human leukocyte antigen class I molecule. Journal of Biological Chemistry 288 (22) , pp. 15442-15454. 10.1074/jbc.M112.447185

Berry, R., Ng, N., Saunders, P., Vivian, J., Lin, J., Deuss, F., Corbett, A., Forbes, C., Widjaja, J., Sullivan, L., McAlister, A., Perugini, M., Call, M., Scalzo, A., Degli-Esposti, M., Coudert, J., Beddoe, T., Brooks, A. and Rossjohn, Jamie

2013. Targeting of a natural killer cell receptor family by a viral immunoevasin. Nature Immunology 14 (7) , pp. 699-705. 10.1038/ni.2605

Valkenburg, S., Gras, S., Guillonneau, C., Hatton, L., Bird, N., Twist, K., Halim, H., Jackson, D., Purcell, A., Turner, S, Doherty, P., Rossjohn, Jamie

and Kedzierska, K. 2013. Preemptive priming readily overcomes structure-based mechanisms of virus escape. Proceedings of the National Academy of Sciences of the United States of America 110 (14) , pp. 5570-5575. 10.1073/pnas.1302935110

Ladell, Kristin Ingrid

, Hashimoto, Masao, Iglesias, Maria Candela, Wilmann, Pascal G., McLaren, James Edward

, Gras, Stéphanie, Chikata, Takayuki, Kuse, Nozomi, Fastenackels, Solène, Gostick, Emma, Bridgeman, John S., Venturi, Vanessa, Arkoub, Zaïna Aït, Agut, Henri, van Bockel, David J., Almeida, Jorge R., Douek, Daniel C., Meyer, Laurence, Venet, Alain, Takiguchi, Masafumi, Rossjohn, Jamie

, Price, David

and Appay, Victor 2013. A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells. Immunity 38 (3) , pp. 425-436. 10.1016/j.immuni.2012.11.021

Eukeruche-Makinde, Julia, Miles, John J., Van Den Berg, Hugo A., Skowera, Ania, Cole, David K.

, Dolton, Garry Michael, Schauenburg, Andrea, Tan, Mai Ping, Pentier, Johanne, Llewellyn-Lacey, Sian, Miles, Kim M., Bulek, Anna, Clement, Mathew

, Dockree, Tamsin, Trimby, Andrew R., Bailey, Mick, Rizkallah, Pierre

, Rossjohn, Jamie

, Peakman, Mark, Burrows, Scott, Sewell, Andrew K.

and Wooldridge, Linda 2013. Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood -New York- 121 (7) , pp. 1112-1123. 10.1182/blood-2012-06-437202

Ekeruche, Julia, Miles, John James, van den Berg, Hugo A., Skowera, Ania, Cole, David

, Dolton, Garry Michael, Schauenburg, Andrea J. A., Tan, Mai Ping, Pentier, Johanne, Llewellyn-Lacey, Sian, Miles, Kim Michelle, Bulek, Anna Marta, Clement, Mathew

, Williams, Tamsin, Trimby, Andrew R., Bailey, Mick, Rizkallah, Pierre

, Rossjohn, Jamie

, Peakman, Mark, Price, David

, Burrows, Scott R., Sewell, Andrew K.

and Wooldridge, Linda 2013. Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood 121 (7) , pp. 1112-1123. 10.1182/blood-2012-06-437202

Illing, P. T., Vivan, J. P., Rossjohn, Jamie

and McCluskey, J. 2013. Human leukocyte antigen-associated drug hypersensitivity [review]. Current Opinion in Immunology 25 (1) , pp. 81-89. 10.1016/j.coi.2012.10.002

Vavassori, Stefano, Kumar, Anil, Wan, Gan Siok, Ramanjaneyulu, Gundimeda S., Cavallari, Marco, El Daker, Sary, Beddoe, Travis, Theodossis, Alex, Williams, Neal K., Gostick, Emma, Price, David

, Soudamini, Dinish U., Voon, Kong Kien, Olivo, Malini, Rossjohn, Jamie

, Mori, Lucia and De Libero, Gennaro 2013. Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells. Nature Immunology 14 (9) , pp. 908-916. 10.1038/ni.2665

Uldrich, A., Le Nours, J., Pellicci, D., Gherardin, N., McPherson, K., Lim, R., Patel, O., Beddoe, T., Gras, S., Rossjohn, Jamie

and Godfrey, D. 2013. CD1d-lipid antigen recognition by the γδTCR. Nature Immunology 14 (11) , pp. 1137-1145. 10.1038/ni.2713

Eckle, Sidonia B. G., Rossjohn, Jamie

and McCluskey, James 2013. Alloreactivity. Zachary, Andrea A. and Leffell, Mary S., eds. Transplantation Immunology, Vol. 1034. Methods in Molecular Biology, Springer, pp. 3-39. (10.1007/978-1-62703-493-7_1)

Patel, Onisha, Pellicci, Daniel G., Gras, Stephanie, Sandoval-Romero, Maria L., Uldrich, Adam P., Mallevaey, Thierry, Clarke, Andrew J., Le Nours, Jérôme, Theodossis, Alex, Cardell, Susanna L., Gapin, Laurent, Godfrey, Dale I. and Rossjohn, Jamie

2012. Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor. Nature Immunology 13 (9) , pp. 857-863. 10.1038/ni.2372

Bulek, Anna, Cole, David

, Skowera, Ania, Dolton, Garry, Gras, Stephanie, Madura, Florian, Fuller, Anna, Miles, John, Gostick, Emma, Price, David

, Drijfhout, Jan W, Knight, Robin R, Huang, Guo C, Lissin, Nikolai, Molloy, Peter E, Wooldridge, Linda, Jakobsen, Bent K, Rossjohn, Jamie

, Peakman, Mark, Rizkallah, Pierre

and Sewell, Andrew

2012. Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes. Nature Immunology 13 (3) , pp. 283-289. 10.1038/ni.2206

Vivian, Julian P., Duncan, Renee C., Berry, Richard, O'Connor, Geraldine M., Reid, Hugh H., Beddoe, Travis, Gras, Stephanie, Saunders, Philippa M., Olshina, Maya A., Widjaja, Jacqueline M. L., Harpur, Christopher M., Lin, Jie, Maloveste, Sebastien M., Price, David

, Lafont, Bernard A. P., McVicar, Daniel W., Clements, Craig S., Brooks, Andrew G. and Rossjohn, Jamie

2011. Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B [Letter]. Nature 479 (7373) , pp. 401-405. 10.1038/nature10517

Pellicci, Daniel G., Clarke, Andrew J., Patel, Onisha, Mallevaey, Thierry, Beddoe, Travis, Le Nours, Jérôme, Uldrich, Adam P., McCluskey, James, Besra, Gurdyal S., Porcelli, Steven A., Gapin, Laurent, Godfrey, Dale I. and Rossjohn, Jamie

2011. Recognition of β-linked self glycolipids mediated by natural killer T cell antigen receptors. Nature Immunology 12 (9) , pp. 827-833. 10.1038/ni.2076

Iglesias, M. C., Almeida, J. R., Fastenackels, S., van Bockel, D. J., Hashimoto, M., Venturi, V., Gostick, E., Urrutia, A., Wooldridge, L., Clement, Mathew

, Gras, S., Wilmann, P. G., Autran, B., Moris, A., Rossjohn, Jamie

, Davenport, M. P., Takiguchi, M., Brander, C., Douek, D. C., Kelleher, A. D., Price, David

and Appay, V. 2011. Escape from highly effective public CD8+ T-cell clonotypes by HIV. Blood 118 (8) , pp. 2138-2149. 10.1182/blood-2011-01-328781

Pang, Siew Siew, Berry, Richard, Chen, Zhenjun, Kjer-Nielsen, Lars, Perugini, Matthew A., King, Glenn F., Wang, Christina, Chew, Sock Hui, La Gruta, Nicole L., Williams, Neal K., Beddoe, Travis, Tiganis, Tony, Cowieson, Nathan P., Godfrey, Dale I., Purcell, Anthony W., Wilce, Matthew C. J., McCluskey, James and Rossjohn, Jamie

2010. The structural basis for autonomous dimerization of the pre-T-cell antigen receptor. Nature 467 (7317) , pp. 844-848. 10.1038/nature09448

Beddoe, Travis, Chen, Zhenjun, Clements, Craig S., Ely, Lauren K., Bushell, Simon R., Vivian, Julian P., Kjer-Nielsen, Lars, Pang, Siew Siew, Dunstone, Michelle A., Liu, Yu Chih, Macdonald, Whitney A., Perugini, Matthew A., Wilce, Matthew C.J., Burrows, Scott R., Purcell, Anthony W., Tiganis, Tony, Bottomley, Stephen P., McCluskey, James and Rossjohn, Jamie

2009. Antigen ligation triggers a conformational change within the constant domain of the αβ T cell receptor. Immunity 30 (6) , pp. 777-788. 10.1016/j.immuni.2009.03.018

This list was generated on Fri Jan 31 05:57:33 2025 GMT.