McGuinness, Colin D., Keszenman-Pereyra, David, Dickinson, Paul, Campbell, Colin J., Maltman, Beatrice A., Bachmann, Till T., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Crain, Jason 2010. Base pair mismatch identification with DNA nanoswitch and long lifetime acridine fluorophore. Sensors and Actuators B: Chemical 148 (1) , pp. 342-346. 10.1016/j.snb.2010.04.047 |
Official URL: http://dx.doi.org/10.1016/j.snb.2010.04.047
Abstract
Detection of single base pair mutations in an unlabelled nucleic acid target sequence is demonstrated using the time-resolved measurement of the Förster Resonance Energy Transfer (FRET) between a long lifetime acridine-based fluorophore and a non-fluorescent quencher molecule covalently bound to a DNA Holliday junction-based nanoswitch.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Medicine |
Publisher: | Elsevier |
ISSN: | 0925-4005 |
Date of Acceptance: | 28 April 2010 |
Last Modified: | 23 Oct 2022 14:16 |
URI: | https://orca.cardiff.ac.uk/id/eprint/113218 |
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