Hamilton, Fergus, Schurz, Haiko, Yates, Tom A., Gilchrist, James J., Möller, Marlo, Naranbhai, Vivek, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Timpson, Nicholas J., Genes and Health Research Team, International Tuberculosis Host Genetics Consortium, Parks, Tom and Pollara, Gabriele 2024. Altered IL-6 signalling and risk of tuberculosis: a multi-ancestry mendelian randomisation study. The Lancet Microbe , 100922. 10.1016/S2666-5247(24)00162-9 |
Lazzarino, Runa, Borek, Aleksandra J, Honeyford, Kate, Welch, John, Brent, Andrew J, Kinderlerer, Anne, Cooke, Graham, Patil, Shashank, Gordon, Anthony, Glampson, Ben, Goodman, Philippa, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Daniels, Ron, Costelloe, Céire E and Tonkin-Crine, Sarah 2024. Views and uses of sepsis digital alerts in National Health Service Trusts in England: Qualitative study with health care professionals. JMIR Human Factors 11 , e56949. 10.2196/56949 |
Hamilton, Fergus, Mitchell, Ruth, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Timpson, Nic 2024. Phenotypic associations with the HMOX1 GT(n) repeat in European populations. American Journal of Epidemiology 193 (5) , pp. 718-726. 10.1093/aje/kwad154 |
Macowan, Matthew, Pattaroni, Céline, Bonner, Katie, Chatzis, Roxanne, Daunt, Carmel, Gore, Mindy, Custovic, Adnan, Shields, Michael D., Power, Ultan F., Grigg, Jonathan, Roberts, Graham, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Schwarze, Jürgen, Turner, Steve, Bush, Andrew, Saglani, Sejal, Lloyd, Clare M. and Marsland, Benjamin J. 2024. Deep multi-omic profiling reveals molecular signatures that underpin preschool wheeze and asthma. Journal of Allergy and Clinical Immunology 10.1016/j.jaci.2024.08.017 |
Hamilton, Fergus, Pedersen, Kasper Mønsted, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Nordestgaard, Børge Grønne and Smith, George Davey 2023. Low levels of small HDL particles predict but do not influence risk of sepsis. Critical Care 27 , 389. 10.1186/s13054-023-04589-1 |
Honeyford, Kate, Nwosu, Amen-Patrick, Lazzarino, Runa, Kinderlerer, Anne, Welch, John, Brent, Andrew J., Cooke, Graham, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Patil, Shashank, DiAlS Co-investigators and Costelloe, Ceire E. 2023. Prevalence of electronic screening for sepsis in National Health Service acute hospitals in England. BMJ Health & Care Informatics 30 , e100743. 10.1136/bmjhci-2023-100743 |
Hamilton, Fergus, Mentzer, Alexander J., Parks, Tom, Baillie, J. Kenneth, Smith, George Davey, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Timpson, Nicholas J. 2023. Variation in ERAP2 has opposing effects on severe respiratory infection and autoimmune disease. American Journal of Human Genetics 110 (4) , pp. 691-702. 10.1016/j.ajhg.2023.02.008 |
Hamilton, Fergus, Mitchell, Ruth, Ahmed, Haroon ORCID: https://orcid.org/0000-0002-0634-8548, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Timpson, Nicholas J. 2023. An observational and Mendelian randomisation study on iron status and sepsis. Scientific Reports 13 (1) , 2867. 10.1038/s41598-023-29641-6 |
Hamilton, Fergus, Mitchell, Ruth E, Constantinescu, Andrei, Hughes, David, Cunnington, Aubrey, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Timpson, Nicholas J. 2023. The effect of interleukin-6 signaling on severe malaria: A Mendelian randomization analysis. International Journal of Infectious Diseases 129 , pp. 251-259. 10.1016/j.ijid.2023.02.008 |
Minelli, Cosetta, Hamilton, Fergus W., Thomas, Matt, Arnold, David, Palmer, Tom, Moran, Ed, Mentzer, Alexander J., Maskell, Nick, Baillie, Kenneth, Summers, Charlotte, Hingorani, Aroon, MacGowan, Alasdair, Khandaker, Golam M., Mitchell, Ruth, Davey Smith, George, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Timpson, Nicholas J. 2023. Therapeutic potential of IL6R blockade for the treatment of sepsis and sepsis-related death: A mendelian randomisation study. PLoS Medicine 20 (1) , e1004174. 10.1371/journal.pmed.1004174 |
Hamilton, Fergus, Mitchell, Ruth, Cunnington, Aubrey, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Timpson, Nicholas J. 2022. HMOX1 STR polymorphism and malaria: an analysis of a large clinical dataset. Malaria Journal 21 (1) , 342. 10.1186/s12936-022-04352-x |
Brailey, Phillip M., Evans, Lauren, López-Rodríguez, Juan Carlos, Sinadinos, Anthony, Tyrrel, Victoria, Kelly, Gavin, O’Donnell, Valerie, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, John, Susan and Barral, Patricia 2022. CD1d-dependent rewiring of lipid metabolism in macrophages regulates innate immune responses. Nature Communications 13 , 6723. 10.1038/s41467-022-34532-x |
Sharma, Simran, Zaher, Summia, Rodrigues, Patrícia R. S., Davies, Luke C, Edkins, Sarah, Strang, Angela, Chakraborty, Mallinath, Watkins, W. John ORCID: https://orcid.org/0000-0003-3262-6588, Andrews, Robert, Parkinson, Edward, Angelopoulos, Nicos, Moet, Linda, Shepherd, Freya, Davies, Kate Megan, White, Daniel, Oram, Shaun, Siddall, Kate, Keeping, Vikki, Simpson, Kathryn, Faggian, Federica, Bray, Maryanne, Bertorelli, Claire, Bell, Sarah, Collis, Rachel E., McLaren, James E., Labeta, Mario, O’Donnell, Valerie B. and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2022. mSep: investigating physiological and immune-metabolic biomarkers in septic and healthy pregnant women to predict feto-maternal immune health – a prospective observational cohort study protocol. BMJ Open 12 (9) , e066382. 10.1136/bmjopen-2022-066382 |
Milton, R., Modibbo, F., Gillespie, D. ORCID: https://orcid.org/0000-0002-6934-2928, Alkali, F. I., Mukaddas, A. S., Sa'ad, F. H., Tukur, F. M., Khalid, R. Y., Muhammad, M. Y., Bello, M., Edwin, C. P., Ogudo, E., Iregbu, K. C., Jones, L., Hood, K. ORCID: https://orcid.org/0000-0002-5268-8631, Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228, Sanders, J. ORCID: https://orcid.org/0000-0001-5712-9989, Hassan, B., Yusuf, Belga and Walsh, T. R. ORCID: https://orcid.org/0000-0003-4315-4096 2022. Incidence and sociodemographic, living environment and maternal health associations with stillbirth in a tertiary healthcare setting in Kano, Northern Nigeria. Short title: Incidence and factors associated with stillbirth in Kano, Nigeria. BMC Pregnancy and Childbirth 22 , 692. 10.1186/s12884-022-04971-x |
Hamilton, Fergus, Evans, Rebecca, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and MacGowan, Alasdair 2022. Patients with transplantation have reduced mortality in bacteraemia: Analysis of data from a randomised trial. Journal of Infection 85 (1) , pp. 17-23. 10.1016/j.jinf.2022.05.014 |
Frost, Joe N., Hamilton, Fergus, Arnold, David, Elvers, Karen T., Shah, Akshay, Armitage, Andrew E., Milne, Alice, McKernon, Jorgen, Attwood, Marie, Chen, Yi-ling, Xue, Luzheng, Youngs, Jonathon, Provine, Nicholas M., Bicanic, Tihana, Klenerman, Paul, Drakesmith, Hal and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2022. Evaluation of perturbed iron-homeostasis in a prospective cohort of patients with COVID-19. Wellcome Open Research 77 , 173. 10.12688/wellcomeopenres.17904.1 |
Mummidi, Srinivas, Hamilton, Fergus W., Somers, Julia, Mitchell, Ruth E., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Timpson, Nicholas J. 2022. HMOX1 genetic polymorphisms and outcomes in infectious disease: A systematic review. PLoS ONE 17 (5) , e0267399. 10.1371/journal.pone.0267399 |
Iregbu, Kenneth, Dramowski, Angela, Milton, Rebecca, Nsutebu, Emmanuel, Howie, Stephen R C, Chakraborty, Mallinath, Lavoie, Pascal M, Costelloe, Ceire E and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2022. Global health systems' data science approach for precision diagnosis of sepsis in early life. The Lancet Infectious Diseases 22 (5) , E143-E152. 10.1016/S1473-3099(21)00645-9 |
Pattaroni, Céline, Macowan, Matthew, Chatzis, Roxanne, Daunt, Carmel, Custovic, Adnan, Shields, Michael D., Power, Ultan F., Grigg, Jonathan, Roberts, Graham, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Schwarze, Jürgen, Gore, Mindy, Turner, Steve, Bush, Andrew, Saglani, Sejal, Lloyd, Clare M. and Marsland, Benjamin J. 2022. Early life inter-kingdom interactions shape the immunological environment of the airways. Microbiome 10 (1) , 34. 10.1186/s40168-021-01201-y |
Hamilton, Fergus, Evans, Rebecca, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and MacGowan, Alasdair 2022. Time to positivity in bloodstream infection is not a prognostic marker for mortality: analysis of a prospective multicentre randomized control trial. Clinical Microbiology and Infection 28 (1) , 136.E7-136.E13. 10.1016/j.cmi.2021.05.043 |
Rodrigues, Patrícia R.S. ORCID: https://orcid.org/0000-0003-0768-0013, Picco, Noemi, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2021. Sepsis target validation for repurposing and combining complement and immune checkpoint inhibition therapeutics. Expert Opinion on Drug Discovery 16 (5) , pp. 537-551. 10.1080/17460441.2021.1851186 |
Perucha, Esperanza, Melchiotti, Rossella, Bibby, Jack A., Wu, Wing, Stensgaard Frederiksen, Klaus, Roberts, Ceri A., Hall, Zoe, LeFriec, Gaelle, Robertson, Kevin A., Lavender, Paul, Gerwien, Jens Gammeltoft, Taams, Leonie S., Griffin, Julian L., de Rinaldis, Emanuele, van Baarsen, Lisa G. M., Kemper, Claudia, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Cope, Andrew P. 2019. The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells. Nature Communications 10 , 498. 10.1038/s41467-019-08332-9 |
Dantoft, Widad, Robertson, Kevin A, Watkins, W John ORCID: https://orcid.org/0000-0003-3262-6588, Strobl, Brigit and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2019. Metabolic regulators Nampt and Sirt6 serially participate in the macrophage interferon antiviral cascade. Frontiers in Microbiology 10.3389/fmicb.2019.00355 |
Bah, Saikou Y., Forster, Thorsten, Dickinson, Paul, Kampmann, Beate and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2018. Meta-analysis identification of highly robust and differential immune-metabolic signatures of systemic host response to acute and latent tuberculosis in children and adults. Frontiers in Genetics 9 , 457. 10.3389/fgene.2018.00457 |
Renz, Harald, Adkins, Becky D., Bartfeld, Sina, Blumberg, Richard S., Farber, Donna L., Garssen, Johan, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Hackam, David J., Marsland, Benjamin J., McCoy, Kathy D., Penders, John, Prinz, Immo, Verhasselt, Valerie, von Mutius, Erika, Weiser, Jeffrey N., Wesemann, Duane R. and Hornef, Mathias W. 2017. The neonatal window of opportunity-early priming for life. Journal of Allergy and Clinical Immunology 10.1016/j.jaci.2017.11.019 |
Dantoft, Widad, Martínez-Vicente, Pablo, Jafali, James, Pérez-Martínez, Lara, Martin, Kim, Kotzamanis, Konstantinos, Craigon, Marie, Auer, Manfred, Young, Neil T., Walsh, Paul, Marchant, Arnaud, Angulo, Ana, Forster, Thorsten and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2017. Genomic programming of human neonatal dendritic cells in congenital systemic and in vitro cytomegalovirus infection reveal plastic and robust immune pathway biology responses. Frontiers in Immunology 8 , 1146. 10.3389/fimmu.2017.01146 |
Benson, Helen E, Watterson, Steven, Sharman, Joanna L, Mpamhanga, Chido P, Parton, Andrew, Southan, Christopher, Harmar, Anthony J and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2017. Is systems pharmacology ready to impact upon therapy development? A study on the cholesterol biosynthesis pathway. British Journal of Pharmacology 174 (23) , pp. 4362-4382. 10.1111/bph.14037 |
Newmark, Harry, Dantoft, Widad and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2017. Evolutionary origin of the interferon - Immune metabolic axis: The sterol-Vitamin d link. Frontiers in Immunology 8 , 62. 10.3389/fimmu.2017.00062 |
Robertson, Kevin A. and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2016. Interferon control of the sterol metabolic network: bidirectional molecular circuitry-mediating host protection. Frontiers in Immunology 7 10.3389/fimmu.2016.00634 |
Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Marsden, Morgan, Stacey, Maria, Abdul-Karim, Juneid, Gimeno Brias, Silvia, Costa Bento, Diana Filipa, Scurr, Martin ORCID: https://orcid.org/0000-0002-4120-0688, Weaver, Casey, Carlesso, Gianluca, Clare, Simon, Jones, Simon ORCID: https://orcid.org/0000-0001-7297-9711, Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Jones, Gareth W. and Humphreys, Ian ORCID: https://orcid.org/0000-0002-9512-5337 2016. Cytomegalovirus-specific IL-10-producing CD4+ T cells are governed by type-I IFN-induced IL-27 and promote virus persistence. Plos Pathogens 12 (12) , e1006050. 10.1371/journal.ppat.1006050 |
Noho-Konteh, Fatou, Adetifa, Jane U., Cox, Momodou, Hossin, Safayet, Reynolds, John, Le, My Thanh, Sanyang, Lady Chilel, Drammeh, Abdoulie, Plebanski, Magdalena, Forster, Thorsten, Dickinson, Paul, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Whittle, Hilton, Rowland-Jones, Sarah L., Sutherland, Jayne S. and Flanagan, Katie L. 2016. Sex-differential non-vaccine-specific immunological effects of diphtheria-tetanus-pertussis and measles vaccination. Clinical Infectious Diseases 63 (9) , pp. 1213-1226. 10.1093/cid/ciw492 |
Bah, Saikou Y., Dickinson, Paul, Forster, Thorsten, Kampmann, Beate and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2016. Immune oxysterols: Role in mycobacterial infection and inflammation. The Journal of Steroid Biochemistry and Molecular Biology 169 , pp. 152-163. 10.1016/j.jsbmb.2016.04.015 |
Duffin, Roger, O'Connor, Richard A., Crittenden, Siobhan, Forster, Thorsten, Yu, Cunjing, Zheng, Xiaozhong, Smyth, Danielle, Robb, Calum T., Rossi, Fiona, Skouras, Christos, Tang, Shaohui, Richards, James, Pellicoro, Antonella, Weller, Richard B., Breyer, Richard M., Mole, Damian J., Iredale, John P., Anderton, Stephen M., Narumiya, Shuh, Maizels, Rick M., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Howie, Sarah E., Rossi, Adriano G. and Yao, Chungcan 2016. Prostaglandin E2 constrains systemic inflammation through an innate lymphoid cell-IL-22 axis. Science 351 (6279) , pp. 1333-1338. 10.1126/science.aad9903 |
Ploegh, Hidde L, Robertson, Kevin A., Hsieh, Wei Yuan, Forster, Thorsten, Blanc, Mathieu, Lu, Hongjin, Crick, Peter J., Yutuc, Eylan, Watterson, Steven, Martin, Kimberly, Griffiths, Samantha J., Enright, Anton J., Yamamoto, Mami, Pradeepa, Madapura M., Lennox, Kimberly A., Behlke, Mark A., Talbot, Simon, Haas, Jürgen, Dölken, Lars, Griffiths, William J., Wang, Yuqin, Angulo, Ana and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2016. An interferon regulated microrna provides broad cell-intrinsic antiviral immunity through multihit host-directed targeting of the sterol pathway. PLoS Biology 14 (3) , e1002364. 10.1371/journal.pbio.1002364 |
Walsh, P., Bekaert, M., Carroll, J., Manning, T., Kelly, B., O?Driscoll, A., Lu, X., Smith, C., Dickinson, P., Templeton, K., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Sleator, R. D. 2015. Draft genome sequences of six different Staphylococcus epidermidis clones, isolated individually from preterm neonates presenting with sepsis at Edinburgh's Royal Infirmary. Genome Announcements 3 (3) , e00471-15. 10.1128/genomeA.00471-15 |
Sun, Ren, Kropp, Kai A., Hsieh, Wei Yuan, Isern, Elena, Forster, Thorsten, Krause, Eva, Brune, Wolfram, Angulo, Ana and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2015. A temporal gate for viral enhancers to co-opt toll-like-receptor transcriptional activation pathways upon acute infection. PLoS Pathogens 11 (4) , e1004737. 10.1371/journal.ppat.1004737 |
Kotzamanis, Konstantinos, Angulo, Ana and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2015. Infection homeostasis: implications for therapeutic and immune programming of metabolism in controlling infection. Medical Microbiology and Immunology 204 (3) , pp. 395-407. 10.1007/s00430-015-0402-5 |
Lu, Hongjin, Talbot, Simon, Robertson, Kevin A., Watterson, Steven, Forster, Thorsten, Roy, Douglas and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2015. Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-y in primary macrophages requires endogenous 25-hydroxycholesterol synthesis in primary macrophages requires endogenous 25-hydroxycholesterol synthesis. Steroids 99 , pp. 219-229. 10.1016/j.steroids.2015.02.022 |
Stack, Gabrielle, Jones, Emma, Marsden, Morgan, Stacey, Maria A., Snelgrove, Robert J., Lacaze, Paul, Jacques, Laura C., Cuff, Simone ORCID: https://orcid.org/0000-0002-0546-3579, Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Gallimore, Awen M. ORCID: https://orcid.org/0000-0001-6675-7004, Hussell, Tracy, Wilkinson, Gavin W. G. ORCID: https://orcid.org/0000-0002-5623-0126, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421 and Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337 2015. CD200 receptor restriction of myeloid cell responses antagonizes antiviral immunity and facilitates cytomegalovirus persistence within mucosal tissue. PLoS Pathogens 11 (2) , e1004641. 10.1371/journal.ppat.1004641 |
O'Driscoll, Aisling, Belogrudov, Vladislav, Carroll, John, Kropp, Kai, Walsh, Paul, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Sleator, Roy D. 2015. HBLAST: parallelised sequence similarity - A Hadoop MapReducable basic local alignment search tool. Journal of Biomedical Informatics 54 , pp. 58-64. 10.1016/j.jbi.2015.01.008 |
Dickinson, Paul, Smith, Claire L., Forster, Thorsten, Craigon, Marie, Ross, Alan J., Khondoker, Mizan R., Ivens, Alasdair, Lynn, David J., Orme, Judith, Jackson, Allan, Lacaze, Paul, Flanagan, Katie L., Stenson, Benjamin J. and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2014. Whole blood gene expression profiling of neonates with confirmed bacterial sepsis. Genomics Data 3 , pp. 41-48. 10.1016/j.gdata.2014.11.003 |
Kropp, K. A., Lucid, A., Carroll, J., Belgrudov, V., Walsh, P., Kelly, B., Templeton, K., Smith, C., Dickinson, P., O'Driscoll, A., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Sleator, R. D. 2014. Draft genome sequence of a Staphylococcus aureus isolate taken from the blood of a preterm neonatal blood sepsis patient. Genome Announcements 2 (5) , e00906-14. 10.1128/genomeA.00906-14 |
Kropp, K. A., Lucid, A., Carroll, J., Belgrudov, V., Walsh, P., Kelly, B., Templeton, K., Smith, C., Dickinson, P., O'Driscoll, A., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Sleator, R. D. 2014. Draft genome sequence of a Pantoea sp. isolated from a preterm neonatal blood sepsis patient. Genome Announcements 2 (5) , e00904-14. 10.1128/genomeA.00904-14 |
Kropp, K. A., Lucid, A., Carroll, J., Belgrudov, V., Walsh, P., Kelly, B., Smith, C., Dickinson, P., O'Driscoll, A., Templeton, K., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Sleator, R. D. 2014. Draft genome sequence of an Enterococcus faecalis strain isolated from a neonatal blood sepsis patient. Genome Announcements 2 (5) , e00907-14. 10.1128/genomeA.00907-14 |
Kropp, K. A., Lucid, A., Carroll, J., Belgrudov, V., Walsh, P., Kelly, B., Smith, C., Dickinson, P., O'Driscoll, A., Templeton, K., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Sleator, R. D. 2014. Draft genome sequence of a Serratia marcescens strain isolated from a preterm neonatal blood sepsis patient at the Royal Infirmary, Edinburgh, Scotland, United Kingdom. Genome Announcements 2 (5) , e00908-14. 10.1128/genomeA.00908-14 |
Kropp, K. A., Lucid, A., Carroll, J., Belgrudov, V., Walsh, P., Kelly, B., Smith, C., Dickinson, P., O'Driscoll, A., Templeton, K., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Sleator, R. D. 2014. Draft genome sequence of a Staphylococcus warneri strain isolated from a preterm neonate blood sepsis patient at the Royal Infirmary, Edinburgh, Scotland. Genome Announcements 2 (5) , e00877-14. 10.1128/genomeA.00877-14 |
Kropp, K. A., Lucid, A., Carroll, J., Belgrudov, V., Walsh, P., Kelly, B., Smith, C., Dickinson, P., O'Driscoll, A., Templeton, K., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Sleator, R. D. 2014. Draft genome sequence of a Streptococcus agalactiae strain isolated from a preterm neonate blood sepsis patient at the Royal Infirmary, Edinburgh, Scotland. Genome Announcements 2 (5) , e00875-14. 10.1128/genomeA.00875-14 |
Smith, Claire L., Dickinson, Paul, Forster, Thorsten, Craigon, Marie, Ross, Alan, Khondoker, Mizanur R., France, Rebecca, Ivens, Alasdair, Lynn, David J., Orme, Judith, Jackson, Allan, Lacaze, Paul, Flanagan, Katie L., Stenson, Benjamin J. and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2014. Identification of a human neonatal immune-metabolic network associated with bacterial infection. Nature Communications 5 , 4649. 10.1038/ncomms5649 |
Griffiths, Samantha J., Beard, Philippa M., Gonzalez, Orland, Haga, Ismar R., Pechenick Jowers, Tali, Reynolds, Danielle K., Wildenhain, Jan, Tekotte, Hille, Auer, Manfred, Tyers, Mike, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Zimmer, Ralf and Haas, Jürgen 2014. A loss of function analysis of host factors influencing Vaccinia virus replication by RNA interference. PLoS ONE 9 (6) , e98431. 10.1371/journal.pone.0098431 |
Rall, Glenn F., Kropp, Kai A., Angulo, Ana and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2014. Viral enhancer mimicry of host innate-immune promoters. PLoS Pathogens 10 (2) , e1003804. 10.1371/journal.ppat.1003804 |
Cases, M., Furlong, L. I., Albanell, J., Altman, R. B., Bellazzi, R., Boyer, S., Brand, A., Brookes, A. J., Brunak, S., Clark, T. W., Gea, J., Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228, Graf, N., Guigó, R., Klein, T. E., López-Bigas, N., Maojo, V., Mons, B., Musen, M., Oliveira, J. L., Rowe, A., Ruch, P., Shabo, A., Shortliffe, E. H., Valencia, A., van der Lei, J., Mayer, M. A. and Sanz, F. 2013. Improving data and knowledge management to better integrate health care and research. Journal of Internal Medicine 274 (4) , pp. 321-328. 10.1111/joim.12105 |
Trilling, Mirko, Bellora, Nicolás, Rutkowski, Andrzej J., de Graaf, Miranda, Dickinson, Paul, Robertson, Kevin, Prazeres da Costa, Olivia, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Friedel, Caroline C., Albà, M. Mar and Dölken, Lars 2013. Deciphering the modulation of gene expression by type I and II interferons combining 4sU-tagging, translational arrest and in silico promoter analysis. Nucleic Acids Research 41 (17) , pp. 8107-8125. 10.1093/nar/gkt589 |
Gao, Shou-Jiang, Griffiths, Samantha J., Koegl, Manfred, Boutell, Chris, Zenner, Helen L., Crump, Colin M., Pica, Francesca, Gonzalez, Orland, Friedel, Caroline C., Barry, Gerald, Martin, Kim, Craigon, Marie H., Chen, Rui, Kaza, Lakshmi N., Fossum, Even, Fazakerley, John K., Efstathiou, Stacey, Volpi, Antonio, Zimmer, Ralf, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Haas, Jürgen 2013. A systematic analysis of host factors reveals a med23-interferon-λ regulatory axis against herpes simplex virus type 1 replication. PLoS Pathogens 9 (8) , e1003514. 10.1371/journal.ppat.1003514 |
Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Dickinson, Paul and Smith, Claire L. 2013. Early life response to infection. Current Opinion in Infectious Diseases 26 (3) , pp. 213-218. 10.1097/QCO.0b013e32835fb8bf |
Flanagan, K.L., Noho-Konteh, F., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Dickinson, P. 2013. Transcriptional profiling technology for studying vaccine responses: An untapped goldmine. Methods 60 (3) , pp. 269-274. 10.1016/j.ymeth.2013.03.032 |
Mazein, Alexander, Watterson, Steven, Hsieh, Wei-Yuan, Griffiths, William J. and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2013. A comprehensive machine-readable view of the mammalian cholesterol biosynthesis pathway. Biochemical Pharmacology 86 (1) , pp. 56-66. 10.1016/j.bcp.2013.03.021 |
Gibbs, Holly C., Sing, Garwin, Armas, Juan Carlos González, Campbell, Colin J., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Yeh, Alvin T. 2013. Time-lapse ultrashort pulse microscopy of infection in three-dimensional versus two-dimensional culture environments reveals enhanced extra-chromosomal virus replication compartment formation. Journal of Biomedical Optics 18 (3) , 031111. 10.1117/1.JBO.18.3.031111 |
Watterson, Steven, Guerriero, Maria Luisa, Blanc, Mathieu, Mazein, Alexander, Loewe, Laurence, Robertson, Kevin A., Gibbs, Holly, Shui, Guanghou, Wenk, Markus R., Hillston, Jane and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2013. A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction. Biochimie 95 (3) , pp. 613-621. 10.1016/j.biochi.2012.05.024 |
Hambleton, Sophie, Goodbourn, Stephen, Young, Dan F., Dickinson, Paul, Mohamad, Siti M. B., Valappil, Manoj, McGovern, Naomi, Cant, Andrew J., Hackett, Scott J., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Morgan, Neil V. and Randall, Richard E. 2013. STAT2 deficiency and susceptibility to viral illness in humans. Proceedings of the National Academy of Sciences 110 (8) , 201220098. 10.1073/pnas.1220098110 |
Piotrowski, M., McGilvary, G. A., Sloan, T. M., Mewissen, M., Lloyd, A. D., Forster, T., Mitchell, L., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Hill, J. 2013. Exploiting parallel R in the cloud with SPRINT. Methods of Information in Medicine 52 (1) , pp. 80-90. 10.3414/ME11-02-0039 |
Blanc, Mathieu, Hsieh, Wei Yuan, Robertson, Kevin A., Kropp, Kai A., Forster, Thorsten, Shui, Guanghou, Lacaze, Paul, Watterson, Steven, Griffiths, Samantha J., Spann, Nathanael J., Meljon, Anna, Talbot, Simon, Krishnan, Kathiresan, Covey, Douglas F., Wenk, Markus R., Craigon, Marie, Ruzsics, Zsolts, Haas, Jürgen, Angulo, Ana, Griffiths, William J., Glass, Christopher K., Wang, Yuqin and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2013. The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response. Immunity 38 (1) , pp. 106-118. 10.1016/j.immuni.2012.11.004 |
Mitchell, Lawrence, Sloan, Terence M., Mewissen, Muriel, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Forster, Thorsten, Piotrowski, Michal and Trew, Arthur 2012. Parallel classification and feature selection in microarray data using SPRINT. Concurrency and Computation: Practice and Experience 26 (4) , pp. 854-865. 10.1002/cpe.2928 |
Britt, William J., Rodríguez-Martín, Sara, Kropp, Kai Alexander, Wilhelmi, Vanessa, Lisnic, Vanda Juranic, Hsieh, Wei Yuan, Blanc, Mathieu, Livingston, Andrew, Busche, Andreas, Tekotte, Hille, Messerle, Martin, Auer, Manfred, Fraser, Iain, Jonjic, Stipan, Angulo, Ana, Reddehase, Matthias J. and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2012. Ablation of the regulatory IE1 protein of murine cytomegalovirus alters in vivo pro-inflammatory TNF-alpha production during acute infection. PLoS Pathogens 8 (8) , e1002901. 10.1371/journal.ppat.1002901 |
Maojo, Victor, Fritts, Martin, Martin-Sanchez, Fernando, De la Iglesia, Diana, Cachau, Raul E., Garcia-Remesal, Miguel, Crespo, Jose, Mitchell, Joyce A., Anguita, Alberto, Baker, Nathan, Barreiro, Jose Maria, Benitez, Sonia E., De la Calle, Guillermo, Facelli, Julio C., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Geissbuhler, Antoine, Gonzalez-Nilo, Fernando, Graf, Norbert, Grangeat, Pierre, Hermosilla, Isabel, Hussein, Rada, Kern, Josipa, Koch, Sabine, Legre, Yannick, Lopez-Alonso, Victoria, Lopez-Campos, Guillermo, Milanesi, Luciano, Moustakis, Vassilis, Munteanu, Cristian, Otero, Paula, Pazos, Alejandro, Perez-Rey, David, Potamias, George, Sanz, Ferran and Kulikowski, Casimir 2012. Nanoinformatics: developing new computing applications for nanomedicine. Computing 94 (6) , pp. 521-539. 10.1007/s00607-012-0191-2 |
Planas-Iglesias, Joan, Guney, Emre, García-García, Javier, Robertson, Kevin A, Raza, Sobia, Freeman, Tom C., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Oliva, Baldo 2012. Extending signaling pathways with protein-Interaction networks. Application to apoptosis. OMICS 16 (5) , pp. 245-256. 10.1089/omi.2011.0130 |
Corrigan, Damion K., Schulze, Holger, Henihan, Grace, Ciani, Ilenia, Giraud, Gerard, Terry, Jonathan G., Walton, Anthony J., Pethig, Ronald, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Crain, Jason, Campbell, Colin J., Mount, Andrew R. and Bachmann, Till T. ORCID: https://orcid.org/0000-0002-7917-5799 2012. Impedimetric detection of single-stranded PCR products derived from methicillin resistant staphylococcus aureus (MRSA) isolates. Biosensors and Bioelectronics 34 (1) , pp. 178-184. 10.1016/j.bios.2012.01.040 |
Akman, O. E., Watterson, S., Parton, A., Binns, N., Millar, A. J. and Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 2012. Digital clocks: simple Boolean models can quantitatively describe circadian systems. Interface 9 (74) , pp. 2365-2382. 10.1098/rsif.2012.0080 |
Damania, Blossom, Fliss, Patricia M., Jowers, Tali Pechenick, Brinkmann, Melanie M., Holstermann, Barbara, Mack, Claudia, Dickinson, Paul, Hohenberg, Heinrich, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Brune, Wolfram 2012. Viral Mediated Redirection of NEMO/IKK? to Autophagosomes Curtails the Inflammatory Cascade. PLoS Pathogens 8 (2) , e1002517. 10.1371/journal.ppat.1002517 |
Ciani, Ilenia, Schulze, Holger, Corrigan, Damion K., Henihan, Grace, Giraud, Gerard, Terry, Jonathan G., Walton, Anthony J., Pethig, Ronald, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Crain, Jason, Campbell, Colin J., Bachmann, Till T. and Mount, Andrew R. 2012. Development of immunosensors for direct detection of three wound infection biomarkers at point of care using electrochemical impedance spectroscopy. Biosensors and Bioelectronics 31 (1) , pp. 413-418. 10.1016/j.bios.2011.11.004 |
Petrou, Savvas, Sloan, Terence M., Mewissen, Muriel, Forster, Thorsten, Piotrowski, Michal, Dobrzelecki, Bartosz, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Trew, Arthur and Hill, Jon 2011. Optimization of a parallel permutation testing function for the SPRINT R package. Concurrency and Computation: Practice and Experience 23 (17) , pp. 2258-2268. 10.1002/cpe.1787 |
Ember, Stuart W. J., Schulze, Holger, Ross, Alan J., Luby, Julie, Khondoker, Mizanur, Giraud, Gerard, Terry, Jonathan G., Ciani, Ilenia, Tlili, Chaker, Crain, Jason, Walton, Anthony J., Mount, Andrew R., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Bachmann, Till T. and Campbell, Colin J. 2011. Fast DNA and protein microarray tests for the diagnosis of hepatitis C virus infection on a single platform. Analytical and Bioanalytical Chemistry 401 (8) , pp. 2549-2559. 10.1007/s00216-011-5332-5 |
Kropp, K. A., Robertson, K. A., Sing, G., Rodriguez-Martin, S., Blanc, M., Lacaze, P., Hassim, M. F. B. N., Khondoker, M. R., Busche, A., Dickinson, P., Forster, T., Strobl, B., Mueller, M., Jonjic, S., Angulo, A. and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2011. Reversible inhibition of murine cytomegalovirus replication by gamma interferon (IFN- ) in primary macrophages involves a primed type I IFN-signaling subnetwork for full establishment of an immediate-early antiviral state. Journal of Virology 85 (19) , pp. 10286-10299. 10.1128/JVI.00373-11 |
Piotrowski, Michal, Forster, Thorsten, Dobrezelecki, Bartosz, Sloan, Terence M., Mitchell, Lawrence, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Mewsissen, Muriel, Petrou, Savvas, Trew, Arthur and Hill, Jon 2011. Optimisation and parallelisation of the partitioning around medoids function in R. p. 707. 10.1109/HPCSim.2011.5999896 |
Giraud, Gerard, Pethig, Ronald, Schulze, Holger, Henihan, Grace, Terry, Jonathan G., Menachery, Anoop, Ciani, Ilenia, Corrigan, Damion, Campbell, Colin J., Mount, Andrew R., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Walton, Anthony J., Crain, Jason and Bachmann, Till T. 2011. Dielectrophoretic manipulation of ribosomal RNA. Biomicrofluidics 5 (2) , 024116. 10.1063/1.3604395 |
Engel, Pablo, Pérez-Carmona, Natàlia, Albà, M Mar, Robertson, Kevin, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Angulo, Ana 2011. Human cytomegalovirus UL7, a homologue of the SLAM-family receptor CD229, impairs cytokine production. Immunology and Cell Biology 89 (7) , pp. 753-766. 10.1038/icb.2011.55 |
Mitchell, Lawrence, Sloan, Terence M., Mewissen, Muriel, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Forster, Thorsten, Piotrowski, Michal and Trew, Arthur S. 2011. A parallel random forest classifier for R. p. 1. 10.1145/1996023.1996024 |
Lacaze, P., Forster, T., Ross, A., Kerr, L. E., Salvo-Chirnside, E., Lisnic, V. J., Lopez-Campos, G. H., Garcia-Ramirez, J. J., Messerle, M., Trgovcich, J., Angulo, A. and Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 2011. Temporal profiling of the coding and noncoding murine cytomegalovirus transcriptomes. Journal of Virology 85 (12) , pp. 6065-6076. 10.1128/JVI.02341-10 |
Loewe, Laurence, Guerriero, Maria Luisa, Watterson, Steven, Moodie, Stuart, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Hillston, Jane 2011. Translation from the quantified implicit process flow abstraction in SBGN-PD diagrams to Bio-PEPA illustrated on the cholesterol pathway. Priami, C, Back, RJ, Petre, I and de Vink, E, eds. Transactions on Computational Systems Biology XIII, Lecture Notes in Computer Science, Germany: pp. 13-38. (10.1007/978-3-642-19748-2_2) |
Virgin, Skip W., Blanc, Mathieu, Hsieh, Wei Yuan, Robertson, Kevin A., Watterson, Steven, Shui, Guanghou, Lacaze, Paul, Khondoker, Mizanur, Dickinson, Paul, Sing, Garwin, Rodríguez-Martín, Sara, Phelan, Peter, Forster, Thorsten, Strobl, Birgit, Müller, Matthias, Riemersma, Rudolph, Osborne, Timothy, Wenk, Markus R., Angulo, Ana and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2011. Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis. PLoS Biology 9 (3) , e1000598. 10.1371/journal.pbio.1000598 |
Isern, E., Gustems, M., Messerle, M., Borst, E., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Angulo, A. 2011. The activator protein 1 binding motifs within the human cytomegalovirus major immediate-early enhancer are functionally redundant and act in a cooperative manner with the NF- B sites during acute infection. Journal of Virology 85 (4) , pp. 1732-1746. 10.1128/JVI.01713-10 |
Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Watterson, Steven, Robertson, Kevin and Kluth, David C 2011. The in silico macrophage: toward a better understanding of inflammatory disease. Genome Medicine 3 (1) , p. 4. 10.1186/gm218 |
Schulze, Holger, Ross, Alan J., Ember, Stuart W. J, Luby, Julie, Khondoker, Mizanur, Giraud, Gerard, Ciani, Ilenia, Tlili, Chaker, Papale, Davide, Terry, Jonathan G., Mount, Andrew R., Walton, Anthony J, Crain, Jason, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Bachmann, Till T. and Campbell, Colin J. 2010. Peptide-tags for enhanced DNA microarray performance. Faraday Discussions 149 , pp. 201-210. 10.1039/C005491G |
Ashrafi, G. H., Grinfeld, Esther, Montague, Paul, Forster, Thorsten, Ross, Alan, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Scott, Fiona, Breuer, Judith, Goodwin, Roslyn and Kennedy, Peter G. E. 2010. Assessment of transcriptomal analysis of varicella-zoster-virus gene expression in patients with and without post-herpetic neuralgia. Virus Genes 41 (2) , pp. 192-201. 10.1007/s11262-010-0515-2 |
Santhakumar, D., Forster, T., Laqtom, N. N., Fragkoudis, R., Dickinson, P., Abreu-Goodger, C., Manakov, S. A., Choudhury, N. R., Griffiths, S. J., Vermeulen, A., Enright, A. J., Dutia, B., Kohl, A., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Buck, A. H. 2010. Combined agonist-antagonist genome-wide functional screening identifies broadly active antiviral microRNAs. Proceedings of the National Academy of Sciences 107 (31) , pp. 13830-13835. 10.1073/pnas.1008861107 |
McGuinness, Colin D., Keszenman-Pereyra, David, Dickinson, Paul, Campbell, Colin J., Maltman, Beatrice A., Bachmann, Till T., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Crain, Jason 2010. Base pair mismatch identification with DNA nanoswitch and long lifetime acridine fluorophore. Sensors and Actuators B: Chemical 148 (1) , pp. 342-346. 10.1016/j.snb.2010.04.047 |
Freeman, Tom C, Raza, Sobia, Theocharidis, Athanasios and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2010. The mEPN scheme: an intuitive and flexible graphical system for rendering biological pathways. BMC Systems Biology 4 (1) , 65. 10.1186/1752-0509-4-65 |
Raza, Sobia, McDerment, Neil, Lacaze, Paul A, Robertson, Kevin, Watterson, Steven, Chen, Ying, Chisholm, Michael, Eleftheriadis, George, Monk, Stephanie, O'Sullivan, Maire, Turnbull, Arran, Roy, Douglas, Theocharidis, Athanasios, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Freeman, Tom C 2010. Construction of a large scale integrated map of macrophage pathogen recognition and effector systems. BMC Systems Biology 4 (1) , 63. 10.1186/1752-0509-4-63 |
Watterson, Steven and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2010. Use of logic theory in understanding regulatory pathway signaling in response to infection. Future Microbiology 5 (2) , pp. 163-176. 10.2217/fmb.10.8 |
Khondoker, Mizanur R., Bachmann, Till T., Mewissen, Muries, Dickinson, Paul, Dobrzelecki, Bartosz, Campbell, Colin J., Mount, Andrews R., Walton, Anthony J., Crain, Jason, Schulze, Holger, Giraud, Gerard, Ross, Alan J., Ciani, Ilenia, Ember, Stuart W. J., Tlili, Chaker, Terry, Jonathan G., Grant, Eilidh, McDonnell, Nicola and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2010. Multi-factorial analysis of class prediction error: estimating optimal number of biomarkers for various classification rules. Journal of Bioinformatics and Computational Biology 08 (06) , 945. 10.1142/S0219720010005063 |
Giraud, Gerard, Schulze, Holger, Bachmann, Till T., Campbell, Colin J., Mount, Andrew R., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Khondoker, Mizanur R., Ember, Stuart W.J., Ciani, Ilenia, Tlili, Chaker, Walton, Anthony J., Terry, Jonathan G. and Crain, Jason 2009. Solution state hybridization detection using time-resolved fluorescence anisotropy of quantum dot-DNA bioconjugates. Chemical Physics Letters 484 (4-6) , pp. 309-314. 10.1016/j.cplett.2009.11.032 |
McGuinness, Colin D., Nishimura, Mira K. Y., Keszenman-Pereyra, David, Dickinson, Paul, Campbell, Colin J., Bachmann, Till T., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Crain, Jason 2009. Detection of single nucleotide polymorphisms using a DNA Holliday junction nanoswitch?a high-throughput fluorescence lifetime assay. Molecular BioSystems 6 (2) , pp. 386-390. 10.1039/B913455G |
Kabani, Sarah, Fenn, Katelyn, Ross, Alan, Ivens, Al, Smith, Terry K, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Matthews, Keith 2009. Genome-wide expression profiling of in vivo-derived bloodstream parasite stages and dynamic analysis of mRNA alterations during synchronous differentiation in Trypanosoma brucei. BMC Genomics 10 (1) , 427. 10.1186/1471-2164-10-427 |
Nishimura, Mira K. Y., McGuinness, Colin D., Keszenman-Pereyra, David, Dickinson, Paul, Campbell, Colin J., Bachmann, Till T., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Crain, Jason 2009. Bait-and-switch molecular recognition in nucleic acid sensors: Time-resolved fluorescence, single nucleotide polymorphism detection. Presented at: 2009 Symposium on Photonics and Optoelectronics, Wuhan, China, 14-16 August 2009. 2009 Symposium on Photonics and Optoelectronics. IEEE, 10.1109/SOPO.2009.5230114 |
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Yu, Le, Watterson, Steven, Marshall, Stephen and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2009. Inference of transition probabilities between the attractors in Boolean networks with perturbation. Presented at: 2009 IEEE International Workshop on Genomic Signal Processing and Statistics, Minneapolis, MN, USA, 17-21 May 2009. 2009 IEEE International Workshop on Genomic Signal Processing and Statistics. IEEE, 10.1109/GENSIPS.2009.5174376 |
Campbell, Colin J., Mountford, Christopher P., Stoquert, Helene C., Buck, Amy H., Dickinson, Paul, Ferapontova, Elena, Terry, Jonathan G., Beattie, John S., Walton, Anthony J., Crain, Jason, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Mount, Andrew R. 2009. A DNA nanoswitch incorporating the fluorescent base analogue 2-aminopurine detects single nucleotide mismatches in unlabelled targets. Analyst 134 (9) , pp. 1873-1879. 10.1039/b900325h |
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Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2009. Pathway Biology Approach to Medicine. Handbook of research on systems biology applications in medicine, Medical Information Science Reference, pp. 1-10. (10.4018/978-1-60566-076-9.ch001) |
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Burgess, Stewart T.G., Kenyon, Fiona, O'Looney, Nichola, Ross, Alan J., Kwan, Marisa Chong, Beattie, John S., Petrik, Juraj, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Campbell, Colin J. 2008. A multiplexed protein microarray for the simultaneous serodiagnosis of human immunodeficiency virus/hepatitis C virus infection and typing of whole blood. Analytical Biochemistry 382 (1) , pp. 9-15. 10.1016/j.ab.2008.07.017 |
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Grzegorczyk, Marco, Husmeier, Dirk, Edwards, Kieron D., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Millar, Andrew J. 2008. Modelling non-stationary gene regulatory processes with a non-homogeneous Bayesian network and the allocation sampler. Bioinformatics 24 (18) , pp. 2071-2078. 10.1093/bioinformatics/btn367 |
Yu, Le, Watterson, Steven, Marshall, Stephen and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2008. Inferring Boolean networks with perturbation from sparse gene expression data: a general model applied to the interferon regulatory network. Molecular BioSystems 4 (10) , pp. 1024-1030. 10.1039/b804649b |
Taylor, Chris F, Field, Dawn, Sansone, Susanna-Assunta, Aerts, Jan, Apweiler, Rolf, Ashburner, Michael, Ball, Catherine A, Binz, Pierre-Alain, Bogue, Molly, Booth, Tim, Brazma, Alvis, Brinkman, Ryan R, Michael Clark, Adam, Deutsch, Eric W, Fiehn, Oliver, Fostel, Jennifer, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Gibson, Frank, Gray, Tanya, Grimes, Graeme, Hancock, John M, Hardy, Nigel W, Hermjakob, Henning, Julian, Randall K, Kane, Matthew, Kettner, Carsten, Kinsinger, Christopher, Kolker, Eugene, Kuiper, Martin, Novère, Nicolas Le, Leebens-Mack, Jim, Lewis, Suzanna E, Lord, Phillip, Mallon, Ann-Marie, Marthandan, Nishanth, Masuya, Hiroshi, McNally, Ruth, Mehrle, Alexander, Morrison, Norman, Orchard, Sandra, Quackenbush, John, Reecy, James M, Robertson, Donald G, Rocca-Serra, Philippe, Rodriguez, Henry, Rosenfelder, Heiko, Santoyo-Lopez, Javier, Scheuermann, Richard H, Schober, Daniel, Smith, Barry, Snape, Jason, Stoeckert, Christian J, Tipton, Keith, Sterk, Peter, Untergasser, Andreas, Vandesompele, Jo and Wiemann, Stefan 2008. Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project. Nature Biotechnology 26 (8) , pp. 889-896. 10.1038/nbt.1411 |
Bayne, R. A. L., Forster, T., Burgess, S. T. G., Craigon, M., Walton, M. J., Baird, D. T., Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 and Anderson, R. A. 2008. Molecular profiling of the human testis reveals stringent pathway-specific regulation of RNA expression following gonadotropin suppression and progestogen treatment. Journal of Andrology 29 (4) , pp. 389-403. 10.2164/jandrol.107.004168 |
Dolken, L., Ruzsics, Z., Radle, B., Friedel, C. C., Zimmer, R., Mages, J., Hoffmann, R., Dickinson, P., Forster, T., Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 and Koszinowski, U. H. 2008. High-resolution gene expression profiling for simultaneous kinetic parameter analysis of RNA synthesis and decay. RNA 14 (9) , pp. 1959-1972. 10.1261/rna.1136108 |
Busche, Andreas, Angulo, Ana, Kay-Jackson, Penelope, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Messerle, Martin 2008. Phenotypes of major immediate-early gene mutants of mouse cytomegalovirus. Medical Microbiology and Immunology 197 (2) , pp. 233-240. 10.1007/s00430-008-0076-3 |
Horne, A. W., van den Driesche, S., King, A. E., Burgess, S., Myers, M., Ludlow, H., Lourenco, P., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Williams, A. R., Critchley, H. O. D. and Duncan, W. C. 2008. Endometrial inhibin/activin β-B subunit expression is related to decidualization and Is reduced in tubal ectopic pregnancy. Journal of Clinical Endocrinology and Metabolism 93 (6) , pp. 2375-2382. 10.1210/jc.2008-0136 |
Watterson, Steven, Marshall, Stephen and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2008. Logic models of pathway biology. Drug Discovery Today 13 (9-10) , pp. 447-456. 10.1016/j.drudis.2008.03.019 |
Raza, Sobia, Robertson, Kevin A, Lacaze, Paul A, Page, David, Enright, Anton J, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Freeman, Tom C 2008. A logic-based diagram of signalling pathways central to macrophage activation. BMC Systems Biology 2 (1) , 36. 10.1186/1752-0509-2-36 |
Papadia, Sofia, Soriano, Francesc X, Léveillé, Frédéric, Martel, Marc-Andre, Dakin, Kelly A, Hansen, Henrik H, Kaindl, Angela, Sifringer, Marco, Fowler, Jill, Stefovska, Vanya, Mckenzie, Grahame, Craigon, Marie, Corriveau, Roderick, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Horsburgh, Karen, Yankner, Bruce A, Wyllie, David J A, Ikonomidou, Chrysanthy and Hardingham, Giles E 2008. Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses. Nature Neuroscience 11 (4) , pp. 476-487. 10.1038/nn2071 |
O'Looney, Nichola, Burgess, Stewart T. G., Kwan, Marisa Chong, Ross, Alan J., Robb, Janine, Forster, Thorsten, Beattie, John S., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Petrik, Juraj and Campbell, Colin J. 2008. Evaluation of a protein microarray method for immune-typing erythrocytes in whole blood. Journal of Immunoassay and Immunochemistry 29 (2) , pp. 197-209. 10.1080/15321810801888530 |
Mountford, C. P., Buck, A. H., Campbell, C. J., Dickinson, P., Ferapontova, E. E., Terry, J. G., Beattie, J. S., Walton, A. J., Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228, Mount, A. R. and Crain, J. 2008. Molecular recognition with DNA nanoswitches: effects of single base mutations on structure. Journal of Physical Chemistry B 112 (8) , pp. 2439-2444. 10.1021/jp073817o |
Cheung, Gordon Y.C., Dickinson, Paul, Sing, Garwin, Craigon, Marie, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Parton, Roger and Coote, John G. 2008. Transcriptional responses of murine macrophages to the adenylate cyclase toxin of Bordetella pertussis. Microbial Pathogenesis 44 (1) , pp. 61-70. 10.1016/j.micpath.2007.08.007 |
Buck, A. H., Santoyo-Lopez, J., Robertson, K. A., Kumar, D. S., Reczko, M. and Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 2007. Discrete clusters of virus-encoded microRNAs are associated with complementary strands of the genome and the 7.2-kilobase stable intron in murine cytomegalovirus. Journal of Virology 81 (24) , pp. 13761-13770. 10.1128/JVI.01290-07 |
Smith, Claire L., Dickinson, Paul, Forster, Thorsten, Khondoker, Mizanur, Craigon, Marie, Ross, Alan, Storm, Petter, Burgess, Stewart, Lacaze, Paul, Stenson, Benjamin J. and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2007. Quantitative assessment of human whole blood RNA as a potential biomarker for infectious disease. Analyst 132 (12) , pp. 1200-1209. 10.1039/b707122c |
Buck, Amy H., Campbell, Colin J., Dickinson, Paul, Mountford, Christopher P., Stoquert, Hélène C., Terry, Jonathan G., Evans, Stuart A. G., Keane, Lorraine M., Su, Tsueu-Ju, Mount, Andrew R., Walton, Anthony J., Beattie, John S., Crain, Jason and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2007. DNA Nanoswitch as a Biosensor. Analytical Chemistry 79 (12) , pp. 4724-4728. 10.1021/ac070251r |
Ferapontova, E.E, Terry, J.G, Walton, A.J, Mountford, C.P, Crain, J, Buck, A.H, Dickinson, P, Campbell, C.J, Beattie, J.S, Ghazal, P ORCID: https://orcid.org/0000-0003-0035-2228 and Mount, A.R 2007. Electrochemical deposition of Zn on TiN microelectrode arrays for microanodes. Electrochemistry Communications 9 (2) , pp. 303-309. 10.1016/j.elecom.2006.09.005 |
Glasbey, Chris A., Forster, Thorsten and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2007. Estimation of expression levels in spotted microarrays with saturated pixels. Statistical Applications in Genetics and Molecular Biology 6 (1) 10.2202/1544-6115.1244 |
Terry, Jonathan G., Campbell, Colin J., Ross, Alan J., Livingston, Andrew D., Buck, Amy H., Dickinson, Paul, Mountford, Christopher P., Evans, Stuart A. G., Mount, Andrew R., Beattie, John S., Crain, Jason, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Walton, Anthony J. 2006. Improved silicon nitride surfaces for next-generation microarrays. Langmuir 22 (26) , pp. 11400-11404. 10.1021/la060489v |
Mount, A.R., Mountford, C.P., Evans, S.A.G., Su, T.-J., Buck, A.H., Dickinson, P., Campbell, C.J., Keane, L.M., Terry, J.G., Beattie, J.S., Walton, A.J., Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 and Crain, J. 2006. The stability and characteristics of a DNA Holliday junction switch. Biophysical Chemistry 124 (3) , pp. 214-221. 10.1016/j.bpc.2006.03.020 |
Sorokin, A., Paliy, K., Selkov, A., Demin, O. V., Dronov, S., Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 and Goryanin, I. 2006. The pathway editor: a tool for managing complex biological networks. Ibm Journal of Research and Development 50 (6) , pp. 561-573. 10.1147/rd.506.0561 |
Mountford, C. P., Mount, A. R., Evans, S. A. G., Su, T.-J., Dickinson, P., Buck, A. H., Campbell, C. J., Terry, J. G., Beattie, J. S., Walton, A. J., Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 and Crain, J. 2006. Time-resolved FRET and FLIM of four-way DNA junctions. Journal of Fluorescence 16 (6) , pp. 839-845. 10.1007/s10895-006-0125-5 |
Gustems, M., Borst, E., Benedict, C. A., Perez, C., Messerle, M., Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 and Angulo, A. 2006. Regulation of the transcription and replication cycle of human cytomegalovirus is insensitive to genetic elimination of the cognate NF- B binding sites in the enhancer. Journal of Virology 80 (19) , pp. 9899-9904. 10.1128/JVI.00640-06 |
Grimes, G. R., Wen, T. Q., Mewissen, M., Baxter, R. M., Moodie, S., Beattie, J. S. and Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 2006. PDQ Wizard: automated prioritization and characterization of gene and protein lists using biomedical literature. Bioinformatics 22 (16) , pp. 2055-2057. 10.1093/bioinformatics/btl342 |
Allen, M. J., Forster, T., Schroeder, D. C., Hall, M., Roy, D., Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 and Wilson, W. H. 2006. Locus-specific gene expression pattern suggests a unique propagation strategy for a giant algal virus. Journal of Virology 80 (15) , pp. 7699-7705. 10.1128/JVI.00491-06 |
Critchley, Hilary O.D., Robertson, Kevin A., Forster, Thorsten, Henderson, Teresa A., Williams, Alistair R.W. and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2006. Gene expression profiling of mid to late secretory phase endometrial biopsies from women with menstrual complaint. American Journal of Obstetrics and Gynecology 195 (2) , pp. 406-414. 10.1016/j.ajog.2006.05.002 |
Dickinson, Paul, Campbell, Colin, Evans, Stuart G, Buck, Amy, Mountford, Christopher, Keane, Lorraine, Terry, Jonathan, Su, Tsueu-ju, Mount, Andrew, Walton, Anthony, Beattie, John, Crain, Jason and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2006. Positional characteristics of fluorophores influencing signal output of a DNA nanoswitch. Presented at: Bio Micro and Nanosystems Conference, San Francisco, California, 15-18 January 2006. Bio Micro and Nanosystems Conference 2006. United States: Institute of Electrical & Electronics Engineers (IEEE) Inc, p. 3. 10.1109/BMN.2006.330892 |
Aguilar, J.S., Devi-Rao, G.V., Rice, M.K., Sunabe, J., Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 and Wagner, E.K. 2006. Quantitative comparison of the HSV-1 and HSV-2 transcriptomes using DNA microarray analysis. Virology 348 (1) , pp. 233-241. 10.1016/j.virol.2005.12.036 |
Robb, J. S., Roy, D. J., Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228, Allan, J. and Petrik, J. 2006. Development of non-agglutination microarray blood grouping. Transfusion Medicine 16 (2) , pp. 119-129. 10.1111/j.1365-3148.2005.00628.x |
Campbell, Colin J., O'Looney, Nichola, Chong Kwan, Marisa, Robb, Janine S., Ross, Alan J., Beattie, John S., Petrik, Juraj and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2006. Cell interaction microarray for blood phenotyping. Analytical Chemistry 78 (6) , pp. 1930-1938. 10.1021/ac051651m |
Vo-Dinh, Tuan, Chowdhury, Mustafa H., Lakowicz, Joseph R., Campbell, Colin J., Theofanidou, Eirini, Gryczynski, Zygmunt, Lee, Seung Joon, Baldwin, Angela, Sing, Garwin, Yeh, Alvin T., Crain, Jason, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Coté, Gerard L. 2006. Surface enhanced Raman spectroscopy (SERS) for the detection of intracellular constituents using gold nanoshells. Presented at: SPIE BiOS, San Jose, California, 21-26 January 2006. Proceedings Volume 6099, Plasmonics in Biology and Medicine III; 609905 (2006). Proceedings of SPIE. , vol.6099 Society of Photo-optical Instrumentation Engineers, 10.1117/12.646464 |
Yu, Le, Marshall, S., Forster, T. and Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 2006. Modelling of macrophage gene expression in the interferon pathway. Presented at: 2006 IEEE International Workshop on Genomic Signal Processing and Statistics, College Station, TX, 28-30 May 2006. 2006 IEEE International Workshop on Genomic Signal Processing and Statistics (IEEE Conference Proceedings). United States: IEEE, p. 45. 10.1109/GENSIPS.2006.353148 |
Beattie, J.S., Campbell, C.J., Crain, J., Dickinson, P., Evans, S.A.G., Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228, Keane, L., Magennis, S., Mount, A.R., Mountford, C., Su, T.-J., Terry, J.G. and Walton, A.J. 2005. Interdisciplinary integrated research teams in an academic environment. , vol.1 p. 328. 10.1109/IEMC.2005.1559145 |
Kennedy, P. G. E., Grinfeld, Esther, Craigon, Marie, Vierlinger, Klemens, Roy, Douglas, Forster, Thorsten and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2005. Transcriptomal analysis of varicella-zoster virus infection using long oligonucleotide-based microarrays. Journal of General Virology 86 (10) , p. 2673. 10.1099/vir.0.80946-0 |
Laghaee, Aroosha, Malcolm, Chris, Hallam, John and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2005. Artificial intelligence and robotics in high throughput post-genomics. Drug Discovery Today 10 (18) , pp. 1253-1259. 10.1016/S1359-6446(05)03581-6 |
Wilson, W. H., Schroeder, Declan C., Allen, Michael J., Holden, Matthew T. G., Parkhill, Julian, Barrell, Bart G., Churcher, Carol, Hamlin, Nancy, Mungall, Karen, Norbertczak, Halina, Quail, Michael A., Price, Claire, Rabbinowitsch, Ester, Walker, Danielle, Craigon, Marie, Roy, Douglas and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2005. Complete genome sequence and lytic phase transcription profile of a coccolithovirus. Science 309 (5737) , pp. 1090-1092. 10.1126/science.1113109 |
Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Visser, A. E., Gustems, M., Garcia, R., Borst, E. M., Sullivan, K., Messerle, M. and Angulo, A. 2005. Elimination of ie1 Significantly Attenuates Murine Cytomegalovirus Virulence but Does Not Alter Replicative Capacity in Cell Culture. Journal of Virology 79 (11) , pp. 7182-7194. 10.1128/JVI.79.11.7182-7194.2005 |
Evans, Stuart A.G., Terry, Jonathan G., Plank, Natalie O.V., Walton, Anthony J., Keane, Lorraine M., Campbell, Colin J., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Beattie, John S., Su, Tsueu-Ju, Crain, Jason and Mount, Andrew R. 2005. Electrodeposition of platinum metal on TiN thin films. Electrochemistry Communications 7 (2) , pp. 125-129. 10.1016/j.elecom.2004.11.014 |
Karaca, Gamze, Hargett, Danna, McLean, Tim I., Aguilar, J.S., Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228, Wagner, Edward K. and Bachenheimer, Steven L. 2004. Inhibition of the stress-activated kinase, p38, does not affect the virus transcriptional program of herpes simplex virus type 1. Virology 329 (1) , pp. 142-156. 10.1016/j.virol.2004.08.020 |
Rae, M T, Niven, D., Forster, T., Lathe, R., Critchley, H O D, Ghazal, P ORCID: https://orcid.org/0000-0003-0035-2228 and Hillier, S G 2004. Steroid signalling in human ovarian surface epithelial cells: the response to interleukin-1 determined by microarray analysis. Journal of Endocrinology 183 (1) , pp. 19-28. 10.1677/joe.1.05754 |
Sun, A., Devi-Rao, G. V., Rice, M. K., Gary, L. W., Bloom, D. C., Sandri-Goldin, R. M., Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 and Wagner, E. K. 2004. Immediate-early expression of the herpes simplex virus type 1 ICP27 transcript is not critical for efficient replication In vitro or in vivo. Journal of Virology 78 (19) , p. 10470. 10.1128/JVI.78.19.10470-10478.2004 |
Martin-Sanchez, F, Iakovidis, I, Nørager, S, Maojo, V, de Groen, P, Van der Lei, J, Jones, T, Abraham-Fuchs, K, Apweiler, R, Babic, A, Baud, R, Breton, V, Cinquin, P, Doupi, P, Dugas, M, Eils, R, Engelbrecht, R, Ghazal, P ORCID: https://orcid.org/0000-0003-0035-2228, Jehenson, P, Kulikowski, C, Lampe, K, De Moor, G, Orphanoudakis, S, Rossing, N, Sarachan, B, Sousa, A, Spekowius, G, Thireos, G, Zahlmann, G, Zvárová, J, Hermosilla, I and Vicente, F.J 2004. Synergy between medical informatics and bioinformatics: facilitating genomic medicine for future health care. Journal of Biomedical Informatics 37 (1) , pp. 30-42. 10.1016/j.jbi.2003.09.003 |
Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Beattie, John 2004. Modular sub-systems approach to predictive biomedicine. Drug Discovery Today: BIOSILICO 2 (1) , pp. 2-3. 10.1016/S1741-8364(04)02376-5 |
Benedict, C. A., Angulo, A., Patterson, G., Ha, S., Huang, H., Messerle, M., Ware, C. F. and Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 2004. Neutrality of the Canonical NF- B-Dependent Pathway for Human and Murine Cytomegalovirus Transcription and Replication In Vitro. Journal of Virology 78 (2) , pp. 741-750. 10.1128/JVI.78.2.741-750.2004 |
Campbell, C.J. and Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 2003. Molecular signatures for diagnosis of infection: application of microarray technology. Journal of Applied Microbiology 96 (1) , pp. 18-23. 10.1046/j.1365-2672.2003.02112.x |
Beattie, John and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2003. Post-genomic technologies ? thinking beyond the hype. Drug Discovery Today 8 (20) , pp. 909-910. 10.1016/S1359-6446(03)02862-9 |
Forster, T, Roy, D and Ghazal, P ORCID: https://orcid.org/0000-0003-0035-2228 2003. Experiments using microarray technology: limitations and standard operating procedures. Journal of Endocrinology 178 (2) , pp. 195-204. 10.1677/joe.0.1780195 |
Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228, Messerle, M., Osborn, K. and Angulo, A. 2003. An Essential Role of the Enhancer for Murine Cytomegalovirus In Vivo Growth and Pathogenesis. Journal of Virology 77 (5) , pp. 3217-3228. 10.1128/JVI.77.5.3217-3228.2003 |
Glasbey, C.A. and Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 2003. Combinatorial image analysis of DNA microarray features. Bioinformatics 19 (2) , pp. 194-203. 10.1093/bioinformatics/19.2.194 |
Ebrahimi, B., Dutia, Bernadette M., Roberts, Kim L., Garcia-Ramirez, Jose J., Dickinson, Paul, Stewart, James P., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Roy, Douglas J. and Nash, Anthony A. 2003. Transcriptome profile of murine gammaherpesvirus-68 lytic infection. Journal of General Virology 84 (1) , pp. 99-109. 10.1099/vir.0.18639-0 |
Von Seggern, Dan J, Aguilar, Edith, Kinder, Karen, Fleck, Shonna Kaye, Gonzalez Armas, J.C, Stevenson, Susan C, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Nemerow, Glen R and Friedlander, Martin 2003. In vivo transduction of photoreceptors or ciliary body by intravitreal injection of pseudotyped adenoviral vectors. Molecular Therapy 7 (1) , pp. 27-34. 10.1016/S1525-0016(02)00030-8 |
Yang, W. C., Devi-Rao, G. V., Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228, Wagner, E. K. and Triezenberg, S. J. 2002. General and specific alterations in programming of global viral gene expression during Infection by VP16 activation-deficient mutants of herpes simplex virus type 1. Journal of Virology 76 (24) , pp. 12758-12774. 10.1128/JVI.76.24.12758-12774.2002 |
Alcami, A., Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 and Yewdell, J. W. 2002. Viruses in control of the immune system: Workshop on molecular mechanisms of immune modulation: lessons from viruses. EMBO reports 3 (10) , pp. 927-932. 10.1093/embo-reports/kvf200 |
Aguilar, JS, Roy, D, Ghazal, P ORCID: https://orcid.org/0000-0003-0035-2228 and Wagner, EK 2002. Dimethyl sulfoxide blocks herpes simplex virus-1 productive infection in vitro acting at different stages with positive cooperativity. Application of micro-array analysis. BMC Infectious Diseases 2 (9) 10.1186/1471-2334-2-9 |
Roy, Douglas, Forster, Thorsten, McGeever, Sean, Robertson, Kevin and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2002. Meeting Review: Bioinformatics of Biochips: Accelerating Discovery in Functional Genomics. Comparative and Functional Genomics 3 (4) , pp. 380-386. 10.1002/cfg.179 |
Wagner, Edward K., Garcia Ramirez, J. J., Stingley, S. W., Aguilar, S. A., Buehler, L., Devi-Rao, G. B. and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2002. Practical approaches to long oligonucleotide-based DNA microarray: Lessons from herpesviruses. Progress in Nucleic Acid Research and Molecular Biology 71 , pp. 445-491. 10.1016/S0079-6603(02)71048-9 |
Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2001. DNA microarray technology and integrative viral genomics. Drug Discovery Today 6 (20) , p. 1046. 10.1016/S1359-6446(01)02001-3 |
Redpath, Stella, Angulo, Ana, Gascoigne, Nicholas R. J. and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2001. Immune checkpoints in viral latency. Annual Review of Microbiology 55 (1) , pp. 531-560. 10.1146/annurev.micro.55.1.531 |
Benedict, Chris A, Banks, Theresa A, Senderowicz, Lionel, Ko, Mira, Britt, William J, Angulo, Ana, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Ware, Carl F 2001. Lymphotoxins and cytomegalovirus cooperatively induce interferon-β, establishing host-virus détente. Immunity 15 (4) , pp. 617-626. 10.1016/S1074-7613(01)00222-9 |
Früh, Klaus, Simmen, Kenneth, Luukkonen, B.G.Mattias, Bell, Yolanda C and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2001. Virogenomics: a novel approach to antiviral drug discovery. Drug Discovery Today 6 (12) , pp. 621-627. 10.1016/S1359-6446(01)01808-6 |
Redpath, Stella, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Gascoigne, Nicholas R.J 2001. Hijacking and exploitation of IL-10 by intracellular pathogens. Trends in Microbiology 9 (2) , pp. 86-92. 10.1016/S0966-842X(00)01919-3 |
Garcia-Ramirez, J. J., Ruchti, F., Huang, H., Simmen, K., Angulo, A. and Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 2001. Dominance of virus over host factors in cross-species activation of human cytomegalovirus early gene expression. Journal of Virology 75 (1) , pp. 26-35. 10.1128/JVI.75.1.26-35.2001 |
Angulo, A., Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 and Messerle, M. 2000. The major immediate-early gene ie3 of mouse cytomegalovirus is essential for viral growth. Journal of Virology 74 (23) , pp. 11129-11136. 10.1128/JVI.74.23.11129-11136.2000 |
Monier, Karine, Armas, Juan Carlos González, Etteldorf, Susanne, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Sullivan, Kevin F. 2000. Annexation of the interchromosomal space during viral infection. Nature Cell Biology 2 (9) , pp. 661-665. 10.1038/35023615 |
Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, García-Ramírez, José, González-Armas, Juan C., Kurz, Sabine and Angulo, Ana 2000. Principles of homeostasis in governing virus activation and latency. Immunologic Research 21 (2-3) , pp. 219-223. 10.1385/IR:21:2-3:219 |
Angulo, A., Kerry, D., Huang, H., Borst, E.-M., Razinsky, A., Wu, J., Hobom, U., Messerle, M. and Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 2000. Identification of a boundary domain adjacent to the potent human cytomegalovirus enhancer that represses transcription of the divergent UL127 promoter. Journal of Virology 74 (6) , pp. 2826-2839. 10.1128/JVI.74.6.2826-2839.2000 |
Wang, H., Griffiths, M. N., Burton, D. R. and Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 2000. Rapid antibody responses by low-dose, single-step, dendritic cell-targeted immunization. Proceedings of the National Academy of Sciences 97 (2) , pp. 847-852. 10.1073/pnas.97.2.847 |
Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, González Armas, Juan Carlos, García-Ramírez, José J., Kurz, Sabine and Angulo, Ana 2000. Viruses: Hostages to the Cell. Virology 275 (2) , pp. 233-237. 10.1006/viro.2000.0553 |
Stingley, S. W., Ramirez, J. J. G., Aguilar, S. A., Simmen, K., Sandri-Goldin, R. M., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Wagner, E. K. 2000. Global analysis of herpes simplex virus type 1 transcription using an oligonucleotide-based DNA microarray. Journal of Virology 74 (21) , pp. 9916-9927. 10.1128/JVI.74.21.9916-9927.2000 |
Preckel, T., Fung-Leung, Wai-Ping, Cai, Zeling, Vitiello, Antonella, Salter-Cid, Luisa, Winqvist, Ola, Wolfe, Tom G., Von Herrath, Matthias, Angulo, Ana, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Lee, Jiing-Dwan, Fourie, Anne M., Wu, Ying, Pang, Jesse, Ngo, Karen, Peterson, Per A., Früh, Klaus and Yang, Young 1999. Impaired immunoproteasome assembly and immune responses in PA28/ mice. Science 286 (5447) , pp. 2162-2165. 10.1126/science.286.5447.2162 |
Kanakaraj, Palanisamy, Ngo, Karen, Wu, Ying, Angulo, Ana, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Harris, Crafford A., Siekierka, John J., Peterson, Per A. and Fung-Leung, Wai-Ping 1999. DefectiveiInterleukin (IL)-18 - mediated natural killer and T helper cell type 1 responses in IL-1 receptor-associated kinase (IRAK)-deficient mice. Journal of Experimental Medicine 189 (7) , p. 1129. 10.1084/jem.189.7.1129 |
Lee, Kyung Joo, Angulo, Ana, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Janda, Kim D. 1999. Soluble-polymer supported synthesis of a prostanoid library: Identification of antiviral activity. Organic Letters 1 (11) , pp. 1859-1862. 10.1021/ol991130j |
Dickinson, Liliane A., Trauger, John W., Baird, Eldon E., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Dervan, Peter B. and Gottesfeld, Joel M. 1999. Anti-repression of RNA polymerase II transcription by pyrrole−imidazole polyamides. Biochemistry 38 (33) , pp. 10801-10807. 10.1021/bi9912847 |
LeBlanc, James F., McLane, Kathryn E., Parren, Paul W. H. I., Burton, Dennis R. and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 1998. Recognition properties of a sequence-specific DNA binding antibody. Biochemistry 37 (17) , pp. 6015-6022. 10.1021/bi9730792 |
Ahn, K., Angulo, A., Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228, Peterson, P. A., Yang, Y. and Fruh, K. 1996. Human cytomegalovirus inhibits antigen presentation by a sequential multistep process. Proceedings of the National Academy of Sciences 93 (20) , pp. 10990-10995. 10.1073/pnas.93.20.10990 |
Angulo, A., Suto, C., Heyman, R A and Ghazal, P ORCID: https://orcid.org/0000-0003-0035-2228 1996. Characterization of the sequences of the human cytomegalovirus enhancer that mediate differential regulation by natural and synthetic retinoids. Molecular Endocrinology -Baltimore- 10 (7) , pp. 781-793. 10.1210/me.10.7.781 |
Lee, G., Wu, J., Luu, P., Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 and Flores, O. 1996. Inhibition of the association of RNA polymerase II with the preinitiation complex by a viral transcriptional repressor. Proceedings of the National Academy of Sciences 93 (6) , pp. 2570-2575. 10.1073/pnas.93.6.2570 |
McLane, K. E., Burton, D. R. and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 1995. Transplantation of a 17-amino acid alpha-helical DNA-binding domain into an antibody molecule confers sequence-dependent DNA recognition. Proceedings of the National Academy of Sciences of the United States of America 92 (11) , pp. 5214-5218. 10.1073/pnas.92.11.5214 |
Barbas, Shana M., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Barbas, Carlos F. and Burton, Dennis R. 1994. Recognition of DNA by synthetic antibodies. Journal of the American Chemical Society 116 (5) , pp. 2161-2162. 10.1021/ja00084a073 |
Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228 and Nelson, J. A. 1992. Interactions between cytomegalovirus immediate-early proteins and the long terminal repeat of human immunodeficiency virus. Reviews in Medical Virology 3 (1) , pp. 47-55. 10.1002/rmv.1980030107 |
Ghazal, P. ORCID: https://orcid.org/0000-0003-0035-2228, DeMattei, C., Giulietti, E., Kliewer, S. A., Umesono, K. and Evans, R. M. 1992. Retinoic acid receptors initiate induction of the cytomegalovirus enhancer in embryonal cells. Proceedings of the National Academy of Sciences 89 (16) , pp. 7630-7634. 10.1073/pnas.89.16.7630 |
Baracchini, Edgardo, Glezer, Emilia, Fish, Kenneth, Stenberg, Richard M., Nelson, Jay A. and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 1992. An isoform variant of the cytomegalovirus immediate-early auto repressor functions as a transcriptional activator. Virology 188 (2) , pp. 518-529. 10.1016/0042-6822(92)90506-K |
Nelson, Jay A., Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 and Wiley, Clayton A. 1990. Role of opportunistic viral infections in AIDS. AIDS 4 (1) , pp. 1-10. 10.1097/00002030-199001000-00001 |
Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Lubon, Henryk, Reynolds-Kohler, Catherine, Hennighausen, Lothar and Nelson, Jay A. 1990. Interactions between cellular regulatory proteins and a unique sequence region in the human cytomegalovirus major immediate-early promoter. Virology 174 (1) , pp. 18-25. 10.1016/0042-6822(90)90049-W |
Al-Shawi, Raya, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Clark, A. John and Bishop, John O. 1989. Intraspecific evolution of a gene family coding for urinary proteins. Journal of Molecular Evolution 29 (4) , pp. 302-313. 10.1007/BF02103618 |
Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Lubon, H., Fleckenstein, B. and Hennighausen, L. 1987. Binding of transcription factors and creation of a large nucleoprotein complex on the human cytomegalovirus enhancer. Proceedings of the National Academy of Sciences 84 (11) , pp. 3658-3662. 10.1073/pnas.84.11.3658 |