Dry heat and microwave generated steam protocols for the rapid decontamination of respiratory personal protective equipment in response to COVID-19-related shortages

Pascoe, M. J. ORCID: https://orcid.org/0000-0002-7794-8970, Robertson, A. ORCID: https://orcid.org/0000-0001-5345-7846, Crayford, A. ORCID: https://orcid.org/0000-0002-6921-4141, Durand, E. ORCID: https://orcid.org/0000-0001-7498-1129, Steer, J. ORCID: https://orcid.org/0000-0002-3003-4768, Castelli, A., Wesgate, R., Evans, S. L. ORCID: https://orcid.org/0000-0003-3664-2569, Porch, A. ORCID: https://orcid.org/0000-0001-5293-8883 and Maillard, J. -Y. ORCID: https://orcid.org/0000-0002-8617-9288 2020. Dry heat and microwave generated steam protocols for the rapid decontamination of respiratory personal protective equipment in response to COVID-19-related shortages. Journal of Hospital Infection 106 (1) , pp. 10-19. 10.1016/j.jhin.2020.07.008

PDF - Accepted Post-Print Version Available under License Creative Commons Attribution Non-commercial No Derivatives. Download (390kB)

Abstract

Background In the wake of SARS-CoV-2 pandemic and unprecedented global demand, clinicians are struggling to source adequate access to personal protective equipment. Respirators can be in short supply, though are necessary to protect workers from SARS-CoV-2 exposure. Rapid decontamination and reuse of respirators may provide relief for the strained procurement situation. Method In this study, we investigated the suitability of 70oC dry heat and microwave-generated steam (MGS) for reprocessing of FFP2/N95-type respirators, and Type-II surgical face masks. S. aureus was used as surrogate as it is less susceptible than enveloped viruses to chemical and physical processes. Results We observed >4 log10 reductions in the viability of dry S. aureus treated by dry heat for 90 minutes at 70°C and >6 log10 reductions by MGS in 90 seconds. After 3 reprocessing cycles, neither process was found to negatively impact the bacterial or NaCl filtration efficiency of the respirators that were tested. However, MGS was incompatible with Type-II surgical masks tested, as we confirmed that bacterial filtration capacity was completely lost following reprocessing. MGS was observed to be incompatible with some respirator types due to arcing observed around some types of metal nose clips and by loss of adhesion of clips to the mask. Conclusion Considering the advantages and disadvantages of each approach, we propose a reprocessing PPE/face mask workflow for use in medical areas.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Pharmacy Engineering
Publisher:	Elsevier
ISSN:	0195-6701
Date of First Compliant Deposit:	16 July 2020
Date of Acceptance:	6 July 2020
Last Modified:	11 Oct 2024 20:02
URI:	https://orca.cardiff.ac.uk/id/eprint/133533

Citation Data

Cited 39 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item