Working with Randy: the diacylglycerol acyltransferase story

Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612 2020. Working with Randy: the diacylglycerol acyltransferase story. Lipids 55 (5) , pp. 419-423. 10.1002/lipd.12267

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Abstract

Vegetable oils are one of the main agricultural commodities. Demand has been increasing steadily over the last five decades and, with finite land available, it is vital that we increase productivity. My laboratory has focused on the regulation of plant lipid metabolism and, as part of this work, we identified diacylglycerol acyltransferase (DGAT) as important at regulating carbon flux during oil accumulation. This led to collaborations with Randy Weselake's research group when we quantified the importance of DGAT in oilseed rape by using flux control analysis. Later, with David Taylor, we showed that over‐expression of DGAT boosted oil accumulation in field‐grown crops by around 8%. These studies led to a multitude of experiments with different oil crops, such as oil palm and soybean, as well as many rewarding collaborations with Randy.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Biosciences
Additional Information:	Published in - Special Issue: Contributions Honoring the Career of Randall J. Weselake: From Plant Lipid to Cancer Lipid Biochemistry
Publisher:	Springer Verlag (Germany)
ISSN:	0024-4201
Date of First Compliant Deposit:	27 July 2020
Date of Acceptance:	17 June 2020
Last Modified:	04 May 2023 10:15
URI:	https://orca.cardiff.ac.uk/id/eprint/133781

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