myo-Inositol Monophosphatase: A Challenging Target for Mood Stabilising Drugs

Miller, D. J. and Allemann, Rudolf Konrad ORCID: https://orcid.org/0000-0002-1323-8830 2007. myo-Inositol Monophosphatase: A Challenging Target for Mood Stabilising Drugs. Mini-Reviews in Chemistry 7 (2) , pp. 107-113. 10.2174/138955707779802624

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Abstract

myo-Inositol monophosphatase has long been a target for drug discovery. Recent work has given detailed insight into its mechanism and dynamics plus new activities and some novel series of inhibitors. The goal of a bio-available inhibitor for this enzyme, however, remains a major challenge for medicinal chemistry.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Chemistry Cardiff Catalysis Institute (CCI)
Subjects:	Q Science > QD Chemistry
Uncontrolled Keywords:	diacylglycerol; G-protein coupled receptor; Lithitum; myo-Inositol 1-phosphate; Circular dichroism; Zinc ion
Publisher:	Bentham Science
ISSN:	1389-5575
Last Modified:	18 Oct 2022 13:20
URI:	https://orca.cardiff.ac.uk/id/eprint/13497

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