Genomic assemblies of members of Burkholderia and related genera as a resource for natural product discovery

Mullins, Alex J. ORCID: https://orcid.org/0000-0001-5804-9008, Jones, Cerith ORCID: https://orcid.org/0000-0001-6275-0235, Bull, Matthew, Webster, Gordon ORCID: https://orcid.org/0000-0002-9530-7835, Parkhill, Julian, Connor, Thomas R. ORCID: https://orcid.org/0000-0003-2394-6504, Murray, James A. H. ORCID: https://orcid.org/0000-0002-2282-3839, Challis, Gregory L. and Mahenthiralingam, Eshwar ORCID: https://orcid.org/0000-0001-9014-3790 2020. Genomic assemblies of members of Burkholderia and related genera as a resource for natural product discovery. Microbiology Resource Announcements 9 , e00485-20. 10.1128/MRA.00485-20

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Abstract

The genomes of 450 members of Burkholderiaceae, isolated from clinical and environmental sources, were sequenced and assembled as a resource for genome mining. Genomic analysis of the collection has enabled the identification of multiple metabolites and their biosynthetic gene clusters, including the antibiotics gladiolin, icosalide A, enacyloxin, and cepacin A.

Item Type:	Article
Date Type:	Published Online
Status:	Published
Schools:	Biosciences
Publisher:	American Society for Microbiology
Funders:	BBSRC, MRC
Date of First Compliant Deposit:	6 October 2020
Date of Acceptance:	21 September 2020
Last Modified:	15 Nov 2024 22:24
URI:	https://orca.cardiff.ac.uk/id/eprint/135323

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