Tumor-associated high endothelial venules: inroads enabling immune control of cancer progression

Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 2022. Tumor-associated high endothelial venules: inroads enabling immune control of cancer progression. Cancer Immunology Research 10 (4) , 371. 10.1158/2326-6066.CIR-22-0112

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Abstract

Infiltration of lymphocytes into solid tumors represents a significant bottleneck to successful control of tumor growth. The nature of tumor blood vessels is an important factor governing both quantitative and qualitative features of the immune infiltrate. In this issue, Sawada and colleagues identify a genetic signature for blood vessels, most notably high endothelial venules, which are associated with tertiary lymphoid structures and improved clinical outcome.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Publisher:	American Association for Cancer Research
ISSN:	2326-6066
Date of First Compliant Deposit:	26 July 2022
Date of Acceptance:	14 February 2022
Last Modified:	14 Nov 2024 23:00
URI:	https://orca.cardiff.ac.uk/id/eprint/151472

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