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Number of items: 109.

Padilha, Ana, Jones, Emma, Cutting, Scott, Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2024. Regulatory T Cells play a role in determining the tumourigenicity of the Intestinal Stem Cell Niche. Gastro Hep Advances 10.1016/j.gastha.2024.09.014
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Hopkins, Georgina, Gomez, Nancy, Tucis, Davis, Bartlett, Laura, Steers, Graham, Burns, Ellie, Brown, Michaela, Harvey-Cowlishaw, Tyler, Santos, Rute, Lauder, Sarah N, Scurr, Martin ORCID: https://orcid.org/0000-0002-4120-0688, Capitani, Lorenzo, Burnell, Stephanie, Rees, Tara, Smart, Kathryn, Somerville, Michelle, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004, Perera, Marianne, Potts, Martin, Metaxaki, Marina, Krishna, Benjamin, Jackson, Hannah, Tighe, Paddy, Onion, David, Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567, Wills, Mark and Fairclough, Lucy 2024. Lower humoral and cellular immunity following asymptomatic SARS-CoV-2 infection compared to symptomatic infection in education (the ACE cohort). Journal of Clinical Immunology 44 (6) , 147. 10.1007/s10875-024-01739-0
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Hulin-Curtis, Sarah, Geary, James, MacLachlan, Bruce, Altmann, Danny, Baillon, Laury, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Greenshields-Watson, Alex, Hesketh, Sophie, Humphreys, Ian ORCID: https://orcid.org/0000-0002-9512-5337, Jones, Ian, Lauder, Sarah, Mason, Georgina, Smart, Kathryn, Scourfield, Oliver, Scott, Jake, Sukhova, Ksenia, Stanton, Richard ORCID: https://orcid.org/0000-0002-6799-1182, Wall, Aaron, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Barclay, Wendy, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2024. A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4+ T cell activation. Cell Reports 43 (6) , 114259. 10.1016/j.celrep.2024.114259
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Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Tournier, Cathy 2023. Immuno-oncology. Essays in Biochemistry 67 (6) , p. 903. 10.1042/EBC20230071
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Chen, Yuan, Mason, Georgina H., Scourfield, D. Oliver, Greenshields-Watson, Alexander, Haigh, Tracey A., Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Long, Heather M., Gallimore, Awen M. ORCID: https://orcid.org/0000-0001-6675-7004, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, MacLachlan, Bruce J. and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2023. Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4+ T cell immunity. Cell Reports 42 (8) , 112827. 10.1016/j.celrep.2023.112827
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Milutinovic, Stefan ORCID: https://orcid.org/0000-0002-3163-3383 and Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 2023. The link between T cell activation and development of functionally useful tumour-associated high endothelial venules. Discovery Immunology 2 (1) , kyad006. 10.1093/discim/kyad006
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Milutinovic, Stefan ORCID: https://orcid.org/0000-0002-3163-3383, Abe, Jun, Jones, Emma, Kelch, Inken, Smart, Kathryn, Lauder, Sarah N., Somerville, Michelle, Ware, Carl, Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567, Stein, Jens V., Bogle, Gib and Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 2022. Three-dimensional imaging reveals immune-driven tumor-associated high endothelial venules as a key correlate of tumor rejection following depletion of regulatory T cells. Cancer Research Communications 2 (12) , pp. 1641-1656. 10.1158/2767-9764.CRC-21-0123
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Lauder, Sarah N., Smart, Kathryn, Bart, Valentina M. T., Pires, Ana, Scott, Jake, Milutinovic, Stefan ORCID: https://orcid.org/0000-0002-3163-3383, Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567, Vanhaesebroeck, Bart and Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 2022. Treg-driven tumour control by PI3Kδ inhibition limits myeloid-derived suppressor cell expansion. British Journal of Cancer 127 , 1595–1602. 10.1038/s41416-022-01917-0
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Scurr, Martin J. ORCID: https://orcid.org/0000-0002-4120-0688, Lippiatt, George, Capitani, Lorenzo, Bentley, Kirsten ORCID: https://orcid.org/0000-0002-6619-2098, Lauder, Sarah N., Smart, Kathryn, Somerville, Michelle S., Rees, Tara, Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004, Hindley, James P. and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2022. Magnitude of venous or capillary blood-derived SARS-CoV-2-specific T cell response determines COVID-19 immunity. Nature Communications 13 , 5422. 10.1038/s41467-022-32985-8
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Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 2022. Tumor-associated high endothelial venules: inroads enabling immune control of cancer progression. Cancer Immunology Research 10 (4) , 371. 10.1158/2326-6066.CIR-22-0112
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Pires, Ana, Burnell, Stephanie and Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 2022. Exploiting ECM remodelling to promote immune-mediated tumour destruction. Current Opinion in Immunology 74 , pp. 32-38. 10.1016/j.coi.2021.09.006
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Scurr, Martin ORCID: https://orcid.org/0000-0002-4120-0688, Zelek, Wioleta, Lippiatt, George, Somerville, Michelle, Burnell, Stephanie, Capitani, Lorenzo, Davies, Kate, Lawton, Helen, Tozer, Thomas, Rees, Tara, Roberts, Kerry, Evans, Mererid, Jackson, Amanda, Young, Charlotte, Fairclough, Lucy, Tighe, Paddy, Wills, Mark, Westwell, Andrew ORCID: https://orcid.org/0000-0002-5166-9236, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2022. Whole blood-based measurement of SARS-CoV-2-specific T cells reveals asymptomatic infection and vaccine immunogenicity in healthy subjects and patients with solid organ cancers. Immunology 165 (2) , pp. 250-259. 10.1111/imm.13433
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Burnell, Stephanie E. A., Capitani, Lorenzo, MacLachlan, Bruce J., Mason, Georgina H., Gallimore, Awen M. ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2021. Seven mysteries of LAG-3: a multi-faceted immune receptor of increasing complexity. Immunotherapy Advances 2 (1) , ltab025. 10.1093/immadv/ltab025
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Teijeira Crespo, Alicia, Burnell, Stephanie, Capitani, Lorenzo, Bayliss, Rebecca ORCID: https://orcid.org/0000-0002-3324-957X, Moses, Elise, Mason, Georgina H., Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Godkin, Andrew J. ORCID: https://orcid.org/0000-0002-1910-7567, Gallimore, Awen M. ORCID: https://orcid.org/0000-0001-6675-7004 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2021. Pouring petrol on the flames: using oncolytic virotherapies to enhance tumour immunogenicity. Immunology 163 (4) , pp. 389-398. 10.1111/imm.13323
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Lauder, Sarah N., Vanhaesebroeck, Bart and Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 2021. Sequential targeting of PI3Kδ and LAG3 as an effective anti-cancer approach. British Journal of Cancer 125 , pp. 467-469. 10.1038/s41416-021-01285-1
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Thomson, Amanda, Costa Bento, Diana F., Scurr, Martin J. ORCID: https://orcid.org/0000-0002-4120-0688, Smart, Kathryn, Somerville, Michelle S., Keita, Åsa V., Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2021. Prognostic significance of interleukin-17A-producing colorectal tumour antigen-specific T cells. British Journal of Cancer 124 , pp. 1552-1555. 10.1038/s41416-021-01283-3
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Milutinovic, Stefan ORCID: https://orcid.org/0000-0002-3163-3383, Abe, Jun, Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567, Stein, Jens V. and Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 2021. The dual role of high endothelial venules in cancer progression versus immunity. Trends in Cancer 7 (3) , pp. 214-225. 10.1016/j.trecan.2020.10.001
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MacLachlan, Bruce J., Mason, Georgina H., Greenshields Watson, Alexander, Triebel, Frederic, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2021. Molecular characterization of HLA class II binding to the LAG-3 T cell co-inhibitory receptor. European Journal of Immunology 51 (2) , pp. 331-341. 10.1002/eji.202048753
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Hanna, Stephanie J., Codd, Amy S., Gea-Mallorqui, Ester, Scourfield, D. Oliver, Richter, Felix C., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Borsa, Mariana, Compeer, Ewoud B., Moon, Owen R., Galloway, Sarah A.E., Dimonte, Sandra, Capitani, Lorenzo, Shepherd, Freya R., Wilson, Joseph D., Uhl, Lion F. K., Ahern, David J., Almuttaqi, Hannah, Alonzi, Dominic S., Alrubayyi, Aljawharah, Alsaleh, Ghada, Bart, Valentina M. T., Batchelor, Vicky, Bayliss, Rebecca, Berthold, Dorothée L., Bezbradica, Jelena S., Bharuchq, Tehmina, Borrmann, Helene, Borsa, Mariana, Borst, Rowie, Brun, Juliane, Burnell, Stephanie, Capitani, Lorenzo, Cavounidis, Athena, Chapman, Lucy, Chauveau, Anne, Cifuentes, Liliana, Codd, Amy Susan, Compeer, Ewoud Bernardus, Coveney, Clarissa, Cross, Amy, Danielli, Sara, Davies, Luke C., Dendrou, Calliope A., Dimonte, Sandra, Peter Durairaj, Ruban Rex, Dustin, Lynn B., Dyer, Arthur, Fielding, Ceri, Fischer, Fabian, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004, Galloway, Sarah, Gammage, Anís, Gea-Mallorquí, Ester, Godkin, Andrew, Hanna, Stephanie J., Heuberger, Cornelia, Hulin-Curtis, Sarah, Issa, Fadi, Jones, Emma, Jones, Ruth, Ladell, Kristin, Lauder, Sarah N., Liddiard, Kate, Ligoxygakis, Petros, Lu, Fangfang, MacLachlan, Bruce, Maleki-Toyserkani, Shayda, Mann, Elizabeth H., Marzeda, Anna M., Matthews, Reginald James, Mazet, Julie M., Milicic, Anita, Mitchell, Emma, Moon, Owen, Nguyen, Van Dien, O'Hanlon, Miriam, Eléonore Pavillet, Clara, Peppa, Dimitra, Pires, Ana, Pring, Eleanor, Quastel, Max, Reed, Sophie, Rehwinkel, Jan, Richmond, Niamh, Richter, Felix Clemens, Robinson, Alice J. B., Rodrigues, Patrícia R. S., Sabberwal, Pragati, Sami, Arvind, Peres, Raphael Sanches, Sattentau, Quentin, Schonfeldova, Barbora, Scourfield, David Oliver, Selvakumar, Tharini A., Shepherd, Freya R., Shorten, Cariad, Simon, Anna Katharina, Smith, Adrian L., Crespo, Alicia Teijeira, Tellier, Michael, Thornton, Emily, Uhl, Lion F. K., van Grinsven, Erinke, Wann, Angus K. T., Williams, Richard, Wilson, Joseph D., Zhou, Dingxi, Zhu, Zihan, Gallimore, Awen M. and Milicic, Anita 2021. T cell phenotypes in COVID-19 - a living review. Oxford Open Immunology 2 (1) 10.1093/oxfimm/iqaa007
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Codd, Amy S., Hanna, Stephanie J., Compeer, Ewoud B., Richter, Felix C., Pring, Eleanor J., Gea-Mallorquí, Ester, Borsa, Mariana, Moon, Owen R., Scourfield, D. Oliver, Gallimore, Awen M. ORCID: https://orcid.org/0000-0001-6675-7004 and Milicic, Anita 2021. Neutrophilia, lymphopenia and myeloid dysfunction: A living review of the quantitative changes to innate and adaptive immune cells which define COVID-19 pathology. Oxford Open Immunology 2 (1) , iqab016. 10.1093/oxfimm/iqab016
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Lauder, S. N., Milutinovic, S. ORCID: https://orcid.org/0000-0002-3163-3383, Pires, A., Smart, K., Godkin, A. ORCID: https://orcid.org/0000-0002-1910-7567 and Gallimore, A. ORCID: https://orcid.org/0000-0001-6675-7004 2021. Using methylcholanthrene-induced fibrosarcomas to study tumor immunology. Methods in Cell Biology, Vol. 163. Elsevier, pp. 59-75. (10.1016/bs.mcb.2020.09.007)

Pires, Ana, Greenshields Watson, Alexander, Jones, Emma, Smart, Kathryn, Lauder, Sarah N., Somerville, Michelle, Milutinovic, Stefan ORCID: https://orcid.org/0000-0002-3163-3383, Kendrick, Howard, Hindley, James P., French, Rhiannon, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146, Watkins, William John ORCID: https://orcid.org/0000-0003-3262-6588, Andrews, Robert, Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 and Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 2020. Immune remodelling of the extracellular matrix drives loss of cancer stem cells and tumor rejection. Cancer Immunology Research 8 (12) , 1520 - 1531. 10.1158/2326-6066.CIR-20-0070
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Hughes, Ellyn, Lauder, Sarah N., Smart, Kathryn, Bloom, Anja, Scott, Jake, Jones, Emma, Somerville, Michelle, Browne, Molly, Blainey, Andrew, Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567, Ager, Ann ORCID: https://orcid.org/0000-0002-5763-8908 and Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 2020. Primary breast tumours but not lung metastases induce protective anti-tumour immune responses after Treg-depletion. Cancer Immunology, Immunotherapy 69 , 2063 - 2073. 10.1007/s00262-020-02603-x
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Lauder, Sarah Nicol, Smart, Kathryn, Kersemans, Veerle, Allen, Danny, Scott, Jake, Pires, Ana, Milutinovic, Stefan ORCID: https://orcid.org/0000-0002-3163-3383, Somerville, Michelle, Smart, Sean, Kinchesh, Paul, Lopez-Guadamillas, Elena, Hughes, Ellyn, Jones, Emma, Scurr, Martin ORCID: https://orcid.org/0000-0002-4120-0688, Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567, Friedman, Lori S, Vanhaesebroeck, Bart and Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 2020. Enhanced antitumor immunity through sequential targeting of PI3Kδ and LAG3. Journal for ImmunoTherapy of Cancer 8 (2) , e000693. 10.1136/jitc-2020-000693
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Greenshields-Watson, Alexander, Attaf, Meriem, MacLachlan, Bruce J., Whalley, Thomas, Rius, Cristina ORCID: https://orcid.org/0000-0002-1896-1649, Wall, Aaron, Lloyd, Angharad, Hughes, Hywel, Strange, Kathryn E., Mason, Georgina H., Schauenburg, Andrea J., Hulin-Curtis, Sarah L. ORCID: https://orcid.org/0000-0003-0889-964X, Geary, James, Chen, Yuan, Lauder, Sarah N., Smart, Kathryn, Vijaykrishna, Dhanasekaran, Grau, Miguel L., Shugay, Mikhail, Andrews, Robert, Dolton, Garry, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Gallimore, Awen M. ORCID: https://orcid.org/0000-0001-6675-7004, Godkin, Andrew J. ORCID: https://orcid.org/0000-0002-1910-7567, Sewell, Andrew J. ORCID: https://orcid.org/0000-0003-3194-3135 and Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396 2020. CD4 + T cells recognize conserved influenza A epitopes through shared patterns of V-Gene usage and complementary biochemical features. Cell Reports 32 (2) , 107885. 10.1016/j.celrep.2020.107885
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Scurr, Martin J. ORCID: https://orcid.org/0000-0002-4120-0688, Greenshields-Watson, Alexander, Campbell, Emma, Somerville, Michelle, Chen, Yuan, Hulin-Curtis, Sarah L. ORCID: https://orcid.org/0000-0003-0889-964X, Burnell, Stephanie E. A., Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Davies, Michael M. ORCID: https://orcid.org/0000-0003-3569-4500, Hargest, Rachel ORCID: https://orcid.org/0000-0001-9830-3832, Phillips, Simon, Christian, Adam D., Ashelford, Kevin E. ORCID: https://orcid.org/0000-0003-3217-2811, Andrews, Robert, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2020. Cancer antigen discovery is enabled by RNA-sequencing of highly purified malignant and non-malignant cells. Clinical Cancer Research 10.1158/1078-0432.CCR-19-3087
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MacLachlan, Bruce J., Dolton, Garry, Papakyriakou, Athanasios, Greenshields-Watson, Alexander, Mason, Georgina H., Schauenburg, Andrea, Besneux, Matthieu, Szomolay, Barbara ORCID: https://orcid.org/0000-0002-5375-5533, Elliott, Tim, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2019. Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope. Journal of Biological Chemistry 294 (52) , pp. 20246-20258. 10.1074/jbc.RA119.009437
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Appanna, Gautham D, Pembroke, Thomas P I ORCID: https://orcid.org/0000-0002-2600-2034, Miners, Kelly L, Price, David A ORCID: https://orcid.org/0000-0001-9416-2737, Gallimore, Awen M ORCID: https://orcid.org/0000-0001-6675-7004, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938 and Godkin, Andrew J ORCID: https://orcid.org/0000-0002-1910-7567 2019. Rituximab depletion of intrahepatic B cells to control refractory hepatic autoimmune overlap syndrome. QJM: An International Journal of Medicine 112 (10) , pp. 793-795. 10.1093/qjmed/hcz161
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Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004, Quezada, Sergio A. and Roychoudhuri, Rahul 2019. Regulatory T cells in cancer: where are we now? Immunology 157 (3) , pp. 187-189. 10.1111/imm.13088
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Thomson, Amanda, Smart, Kathryn, Somerville, Michelle S., Lauder, Sarah N., Appanna, Gautham, Horwood, James, Lawrence-Sunder, Raj, Srivastava, Brijesh, Durai, Dhamaraj, Scurr, Martin J. ORCID: https://orcid.org/0000-0002-4120-0688, Keita, Asa V., Gallimore, Awen M. ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2019. The Ussing chamber system for measuring intestinal permeability in health and disease. BMC Gastroenterology 19 , 98. 10.1186/s12876-019-1002-4
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Watson, H. Angharad, Durairaj, Ruban R.P., Ohme, Julia, Alatsatianos, Markella, Almutairi, Hanan, Mohammed, Rebar N., Vigar, Miriam, Reed, Sophie G., Paisey, Stephen J. ORCID: https://orcid.org/0000-0002-2274-3708, Marshall, Christopher ORCID: https://orcid.org/0000-0002-2228-883X, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Ager, Ann ORCID: https://orcid.org/0000-0002-5763-8908 2019. L-selectin enhanced T cells improve the efficacy of cancer immunotherapy. Frontiers in Immunology 10 , 1321. 10.3389/fimmu.2019.01321
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Besneux, Matthieu, Greenshields Watson, Alexander, Scurr, Martin ORCID: https://orcid.org/0000-0002-4120-0688, MacLachlan, Bruce J., Christian, Adam, Davies, Michael M., Hargest, Rachel ORCID: https://orcid.org/0000-0001-9830-3832, Phillips, Simon, Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 and Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 2019. The nature of the human T cell response to the cancer antigen 5T4 is determined by the balance of regulatory and inflammatory T cells of the same antigen-specificity: implications for vaccine design. Cancer Immunology, Immunotherapy 68 , pp. 247-256. 10.1007/s00262-018-2266-1
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Jones, Emma, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Ager, Ann ORCID: https://orcid.org/0000-0002-5763-8908 2018. Defining high endothelial venules and tertiary lymphoid structures in cancer. Tertiary Lymphoid Structures. Methods in Molecular Biology, Vol. 1845. Methods in Molecular Biology, Humana Press, pp. 99-118. (10.1007/978-1-4939-8709-2_7)
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May, Stephanie, Owen, Heather, Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916, Greenow, Kristy R., Jones, Gareth-Rhys, Blackwood, Adam, Cook, Peter C., Towers, Christopher, Gallimore, Awen M. ORCID: https://orcid.org/0000-0001-6675-7004, Williams, Geraint T., Sturzl, Michael, Britzen-Laurent, Nathalie, Sansom, Owen J., MacDonald, Andrew S., Bird, Adrian P., Clarke, Alan R. and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2018. Mbd2 enables tumourigenesis within the intestine while preventing tumour-promoting inflammation. Journal of Pathology 245 (3) , pp. 270-282. 10.1002/path.5074
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Hill, David, Yu, Liang, Gao, Hugh, Balic, Jesse J., West, Alison, Oshima, Hiroko, McLeod, Louise, Oshima, Masanobu, Gallimore, Awen M. ORCID: https://orcid.org/0000-0001-6675-7004, D'Costa, Kimberley, Bhathal, Prithi S., Sievert, William, Ferrero, Richard L., Jenkins, Brendan J. and Jones, Gareth W. 2018. Hyperactive gp130/STAT3-driven gastric tumourigenesis promotes submucosal tertiary lymphoid structure development. International Journal of Cancer 143 (1) , pp. 167-178. 10.1002/ijc.31298
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Hughes, Ellyn, Scurr, Martin ORCID: https://orcid.org/0000-0002-4120-0688, Campbell, Emma, Jones, Emma, Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 and Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 2018. T‐cell modulation by cyclophosphamide for tumour therapy. Immunology 154 (1) , pp. 62-68. 10.1111/imm.12913
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Miles, John J., Tan, Mai Ping, Dolton, Garry, Edwards, Emily S. J. ORCID: https://orcid.org/0000-0002-0240-4370, Galloway, Sarah A. E., Laugel, Bruno, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Makinde, Julia, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Matthews, Katherine K., Watkins, Thomas S., Tungatt, Katie, Wong, Yide, Lee, Han Siean, Clark, Richard J., Pentier, Johanne M., Attaf, Meriem, Lissina, Anya, Ager, Ann ORCID: https://orcid.org/0000-0002-5763-8908, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Gras, Stephanie, Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522, Burrows, Scott R., Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2018. Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry. Journal of Clinical Investigation 128 (4) , pp. 1569-1580. 10.1172/JCI91512
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Colbeck, Emily Jayne, Ager, Ann, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Jones, Gareth Wyn 2017. Tertiary lymphoid structures in cancer: drivers of antitumor immunity, immunosuppression, or bystander sentinels in disease? Frontiers in Immunology 8 , 1830. 10.3389/fimmu.2017.01830
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Colbeck, Emily J., Jones, Emma, Hindley, James P., Smart, Kathryn, Schulz, Ralph, Browne, Molly, Cutting, Scott, Williams, Anwen ORCID: https://orcid.org/0000-0001-6118-020X, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567, Ware, Carl F., Ager, Ann and Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 2017. Treg depletion licenses T cell-driven HEV neogenesis and promotes tumor destruction. Cancer Immunology Research 5 (11) , pp. 1005-1015. 10.1158/2326-6066.CIR-17-0131
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Scurr, Martin ORCID: https://orcid.org/0000-0002-4120-0688, Pembroke, Tom ORCID: https://orcid.org/0000-0002-2600-2034, Bloom, Anja, Roberts, David, Thomson, Amanda, Smart, Kathryn, Bridgeman, Hayley, Adams, Richard ORCID: https://orcid.org/0000-0003-3915-7243, Brewster, Alison, Jones, Robert ORCID: https://orcid.org/0000-0003-3576-9496, Gwynne, Sarah, Blount, Daniel, Harrop, Richard, Wright, Melissa ORCID: https://orcid.org/0000-0002-1011-4795, Hills, Robert ORCID: https://orcid.org/0000-0003-0166-0062, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2017. Effect of modified vaccinia Ankara–5T4 and low-dose cyclophosphamide on antitumor immunity in metastatic colorectal cancer: A randomized clinical trial. JAMA Oncology 3 (10) , e172579. 10.1001/jamaoncol.2017.2579
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Scurr, Martin J ORCID: https://orcid.org/0000-0002-4120-0688, Pembroke, Tom, Bloom, Anja, Roberts, David J, Thomson, Amanda, Smart, Kathryn, Bridgeman, Hayley, Adams, Richard A ORCID: https://orcid.org/0000-0003-3915-7243, Brewster, Alison E, Jones, Robert ORCID: https://orcid.org/0000-0003-3576-9496, Gwynne, Sarah, Blount, Daniel, Harrop, Richard, Hills, Robert ORCID: https://orcid.org/0000-0003-0166-0062, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2017. Low-dose cyclophosphamide induces anti-tumor T-cell responses which associate with survival in metastatic colorectal cancer. Clinical Cancer Research , clincanres.0895.2017. 10.1158/1078-0432.CCR-17-0895
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Chen, Hung-Chang, Joalland, Noémie, Bridgeman, John S, Alchami, Fouad S, Jarry, Ulrich, Khan, Mohd Wajid A, Piggott, Luke, Shanneik, Yasmin, Li, Jianqiang, Herold, Marco J, Herrmann, Thomas, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Gallimore, Awen M. ORCID: https://orcid.org/0000-0001-6675-7004, Clarkson, Richard W. ORCID: https://orcid.org/0000-0001-7389-8673, Scotet, Emmanuel, Moser, Bernhard ORCID: https://orcid.org/0000-0002-4354-4572 and Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348 2017. Synergistic targeting of breast cancer stem-like cells by human γδ T cells and CD8+ T cells. Immunology and Cell Biology 95 (7) , pp. 620-629. 10.1038/icb.2017.21
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Scurr, Martin ORCID: https://orcid.org/0000-0002-4120-0688, Pembroke, Tom, Adams, Richard ORCID: https://orcid.org/0000-0003-3915-7243, Blount, Daniel, Brewster, Alison, Gwynne, Sarah, Harrop, Richard, Jones, Robert ORCID: https://orcid.org/0000-0003-3576-9496, Hills, Robert ORCID: https://orcid.org/0000-0003-0166-0062, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2017. MVA-5T4 immunotherapy and low-dose cyclophosphamide for advanced colorectal cancer (TaCTiCC): An open-label, randomized phase I/II trial. Journal of Clinical Oncology 35 (7) , p. 154. 10.1200/JCO.2017.35.7_suppl.154
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Hughes, E., Bloom, A., Paisey, Stephen James ORCID: https://orcid.org/0000-0002-2274-3708, Smart, K., Ager, A. and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2016. Treating metastatic disease through manipulation of regulatory T cells. European Journal of Immunology 46 , p. 578. 10.1002/eji.201670200

Colbeck, Emily, Hindley, James P., Smart, Kathryn, Jones, Emma, Bloom, Anja, Bridgeman, Hayley, McPherson, Rhoanne C., Turner, Darryl G., Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, O'Connor, Richard A., Anderton, Stephen M., Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2015. Eliminating roles for T-bet and IL-2 but revealing superior activation and proliferation as mechanisms underpinning dominance of regulatory T cells in tumors. Oncotarget 6 (28) , pp. 24649-24659. 10.18632/oncotarget.5584
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Pembroke, Tom, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 2015. Tracking the kinetics of intrahepatic immune responses by repeated fine needle aspiration of the liver. Journal of Immunological Methods 424 , pp. 131-135. 10.1016/j.jim.2015.04.011
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Ondondo, Beatrice, Colbeck, Emily, Jones, Emma, Smart, Kathryn, Lauder, Sarah Nicol, Hindley, James Philip, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Moser, Bernhard ORCID: https://orcid.org/0000-0002-4354-4572, Ager, Ann ORCID: https://orcid.org/0000-0002-5763-8908 and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2015. A distinct chemokine axis does not account for enrichment of Foxp3+ CD4+T cells in carcinogen-induced fibrosarcomas. Immunology 145 (1) , pp. 94-104. 10.1111/imm.12430
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Scurr, Martin J. ORCID: https://orcid.org/0000-0002-4120-0688, Brown, Clare M., Costa Bento, Diana F., Betts, Gareth J., Rees, Brian I., Hills, Robert K. ORCID: https://orcid.org/0000-0003-0166-0062, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2015. Assessing the prognostic value of preoperative carcinoembryonic antigen-specific T-cell responses in colorectal cancer. JNCI: Journal of the National Cancer Institute 107 (4) , djv001. 10.1093/jnci/djv001
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Costa Bento, Diana Filipa, Jones, Emma, Junaid, Syed, Tull, Justyna, Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Ager, Ann and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2015. High endothelial venules are rare in colorectal cancers but accumulate in extra-tumoral areas with disease progression. OncoImmunology 4 (3) , pp. 653-660. 10.4161/2162402X.2014.974374
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Ford, Catriona A., Petrova, Sofia, Pound, John D., Voss, Jorine J.L.P., Melville, Lynsey, Paterson, Margaret, Farnworth, Sarah L., Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Cuff, Simone, Wheadon, Helen, Dobbin, Edwina, Ogden, Carol Anne, Dumitriu, Ingrid E., Dunbar, Donald R., Murray, Paul G., Ruckerl, Dominik, Allen, Judith E., Hume, David A., van Rooijen, Nico, Goodlad, John R., Freeman, Tom C. and Gregory, Christopher D. 2015. Oncogenic properties of apoptotic tumor cells in aggressive B cell lymphoma. Current Biology 25 (5) , pp. 577-588. 10.1016/j.cub.2014.12.059
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Stack, Gabrielle, Jones, Emma, Marsden, Morgan, Stacey, Maria A., Snelgrove, Robert J., Lacaze, Paul, Jacques, Laura C., Cuff, Simone ORCID: https://orcid.org/0000-0002-0546-3579, Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Gallimore, Awen M. ORCID: https://orcid.org/0000-0001-6675-7004, Hussell, Tracy, Wilkinson, Gavin W. G. ORCID: https://orcid.org/0000-0002-5623-0126, Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228, Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421 and Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337 2015. CD200 receptor restriction of myeloid cell responses antagonizes antiviral immunity and facilitates cytomegalovirus persistence within mucosal tissue. PLoS Pathogens 11 (2) , e1004641. 10.1371/journal.ppat.1004641
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Ondondo, Beatrice, Jones, Emma, Hindley, James, Cutting, Scott, Smart, Kathryn, Bridgeman, Hayley, Matthews, Katherine K., Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Jackson, David G., Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Ager, Ann ORCID: https://orcid.org/0000-0002-5763-8908 and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2014. Progression of carcinogen-induced fibrosarcomas is associated with the accumulation of naïve CD4+ T cellsviablood vessels and lymphatics. International Journal of Cancer 134 (9) , pp. 2156-2167. 10.1002/ijc.28556
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Stacey, Maria A., Marsden, Morgan, Pham N., Tu Anh, Clare, Simon, Dolton, Garry, Stack, Gabrielle, Jones, Emma, Klenerman, Paul, Gallimore, Awen M. ORCID: https://orcid.org/0000-0001-6675-7004, Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421, Snelgrove, Robert J., Lawley, Trevor D., Dougan, Gordon, Benedict, Chris A., Jones, Simon A., Wilkinson, Gavin W. G. ORCID: https://orcid.org/0000-0002-5623-0126 and Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337 2014. Neutrophils recruited by IL-22 in peripheral tissues function as TRAIL-dependent antiviral effectors against MCMV. Cell Host and Microbe 15 (4) , pp. 471-483. 10.1016/j.chom.2014.03.003
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Scurr, Martin ORCID: https://orcid.org/0000-0002-4120-0688, Bloom, Anja, Pembroke, Thomas ORCID: https://orcid.org/0000-0002-2600-2034, Srinivasan, R., Brown, Clare, Smart, Kathryn, Bridgeman, H., Davies, Michael, Hargest, Rachel ORCID: https://orcid.org/0000-0001-9830-3832, Phillips, Simon, Christian, Adam, Hockey, T., Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2013. Escalating regulation of 5T4-specific IFN- + CD4+ T cells distinguishes colorectal cancer patients from healthy controls and provides a target for in vivo therapy. Cancer Immunology Research 1 (6) , 416. 10.1158/2326-6066.CIR-13-0035

Lauder, Sarah Nicol, Jones, Emma, Smart, Kathryn, Bloom, Anja Constanze, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Hindley, James P., Ondondo, Beatrice, Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2013. Interleukin-6 limits influenza-induced inflammation and protects against fatal lung pathology. European Journal of Immunology 43 (10) , pp. 2613-2625. 10.1002/eji.201243018
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Scurr, Martin John ORCID: https://orcid.org/0000-0002-4120-0688, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Besneux, Matthieu, Christian, Adam, Hockey, T., Smart, Kathryn, Bridgeman, Hayley, Hargest, Rachel ORCID: https://orcid.org/0000-0001-9830-3832, Phillips, S., Davies, M., Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 2013. Highly prevalent colorectal cancer-infiltrating LAP+ Foxp3- T cells exhibit more potent immunosuppressive activity than Foxp3+ regulatory T cells. Mucosal Immunology n/a 10.1038/mi.2013.62
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Ondondo, Beatrice, Jones, Emma, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2013. Home sweet home: The tumor microenvironment as a haven for regulatory T cells. Frontiers in Immunology 4 , 197. 10.3389/fimmu.2013.00197
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Pembroke, T. ORCID: https://orcid.org/0000-0002-2600-2034, Gallimore, A. ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, A. ORCID: https://orcid.org/0000-0002-1910-7567 2013. Flow cytometry makes all the difference. Journal of Hepatology 59 (4) , pp. 909-910. 10.1016/j.jhep.2013.05.047

Pembroke, Thomas ORCID: https://orcid.org/0000-0002-2600-2034, Christian, Adam, Jones, Emma, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 2013. The paradox of NKp46+ natural killer cells: drivers of severe hepatitis C virus-induced pathology but in-vivo resistance to interferon treatment. Gut n/a 10.1136/gutjnl-2013-304472
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Pembroke, Thomas, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2013. Rapid innate control of antigen abrogates adaptive immunity. Immunology 138 (4) , pp. 293-297. 10.1111/imm.12048

Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 2013. Epithelial barriers, microbiota, and colorectal cancer. New England Journal of Medicine 368 (3) , pp. 282-284. 10.1056/NEJMcibr1212341

Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Marsden, Morgan, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, McLaren, James Edward ORCID: https://orcid.org/0000-0002-7021-5934, Smart, Kathryn, Hindley, James Philip, Bridgeman, Hayley, van den Berg, Hugo A., Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Ager, Ann ORCID: https://orcid.org/0000-0002-5763-8908, Wooldridge, Linda, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2012. Avidity of influenza-specific memory CD8+T-cell populations decays over time compromising antiviral immunity. European Journal of Immunology 42 (12) , pp. 3235-3242. 10.1002/eji.201242575

Hindley, James Phillip, Jones, Emma, Smart, Kathryn, Bridgeman, Hayley, Lauder, Sarah Nicol, Ondondo, Beatrice Omusiro, Cutting, Scott, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Wynn, Katherine Kay, Withers, David, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Ager, Ann ORCID: https://orcid.org/0000-0002-5763-8908, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2012. T-cell trafficking facilitated by high endothelial venules is required for tumor control after regulatory T cell depletion. Cancer Research 72 (21) , pp. 5473-5482. 10.1158/0008-5472.CAN-12-1912

Scurr, Martin John ORCID: https://orcid.org/0000-0002-4120-0688, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 2012. T cell subsets and colorectal cancer: discerning the good from the bad. Cellular Immunology 279 (1) , pp. 21-24. 10.1016/j.cellimm.2012.08.004

Pembroke, Thomas ORCID: https://orcid.org/0000-0002-2600-2034, Rees, Ian W., Gallagher, Kathleen, Jones, Emma, Mizen, Paul Edward, Navruzov, Timur, Freedman, Andrew Robert, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 2012. Rapid early innate control of hepatitis C virus during IFN-α treatment compromises adaptive CD4+T-cell immunity. European Journal of Immunology 42 (9) , pp. 2383-2394. 10.1002/eji.201142072

Twohig, Jason Peter, Marsden, Morgan, Cuff, Simone ORCID: https://orcid.org/0000-0002-0546-3579, Ferdinand, John R., Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Perks, William Victor, Al-Shamkhani, Aymen, Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337 and Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 2012. The death receptor 3/TL1A pathway is essential for efficient development of antiviral CD4+ and CD8+ T-cell immunity. The FASEB Journal 26 (8) , pp. 3575-3586. 10.1096/fj.11-200618

Kempshall, Emma, Thebault, Simon, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Harris, Claire Louise and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2012. Complement-induced protection: an explanation for the limitations of cell-based tumour immunotherapies. Immunology and Cell Biology 90 (9) , pp. 869-871. 10.1038/icb.2012.30

Pembroke, Thomas ORCID: https://orcid.org/0000-0002-2600-2034, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 2012. PMO-174 Intrahepatic natural killer cell phenotyping and functional analysis by fine needle aspiration in chronic HCV infection. Gut 61 (S2) , A144-A145. 10.1136/gutjnl-2012-302514b.174

Scurr, Martin John ORCID: https://orcid.org/0000-0002-4120-0688, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 2012. PMO-088 A large proportion of colorectal tumour-infiltrating CD4+ T cells are suppressive irrespective of FOXP3 expression. Gut 61 (S2) , A109. 10.1136/gutjnl-2012-302514b.88

Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Gallagher, Kathleen, Lemercier, Brigitte, Holland, Christopher J., Junaid, Sayed, Hindley, James Phillip, Wynn, Katherine Kay, Gostick, Emma, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Gougeon, Marie-Lise and Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 2012. Modification of the carboxy-terminal flanking region of a universal influenza epitope alters CD4+ T-cell repertoire selection. Nature Communications 3 , 665. 10.1038/ncomms1665

Betts, Gareth James, Jones, Emma, Junaid, Syed, El-Shanawany, Tariq, Scurr, Martin John ORCID: https://orcid.org/0000-0002-4120-0688, Mizen, Paul Edward, Kumar, Mayur, Jones, Sion, Rees, Brian Idris, Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 2012. Suppression of tumour-specific CD4+ T cells by regulatory T cells is associated with progression of human colorectal cancer. Gut 61 (8) , pp. 1163-1171. 10.1136/gutjnl-2011-300970

Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Ekeruche, Julia, Miles, John James, Edwards, Emily ORCID: https://orcid.org/0000-0002-0240-4370, Dolton, Garry Michael, Williams, Tamsin, Schauenburg, Andrea J. A., Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Lauder, Sarah Nicol, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Burrows, Scott R., Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 and Wooldridge, Linda 2011. Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining. The Journal of Immunology 187 (2) , pp. 654-663. 10.4049/jimmunol.1003941

Lauder, Sarah Nicol, Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421, Clark, Stephen Robert ORCID: https://orcid.org/0000-0001-5907-9671, Evans, Rhys Lloyd, Hindley, James Phillip, Smart, Kathryn, Leach, Heather, Kidd, Emma Jane ORCID: https://orcid.org/0000-0001-5507-1170, Broadley, Kenneth John ORCID: https://orcid.org/0000-0002-3339-2050, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Wise, Matthew Peter, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2011. Paracetamol reduces influenza-induced immunopathology in a mouse model of infection without compromising virus clearance or the generation of protective immunity. Thorax 66 (5) , pp. 368-374. 10.1136/thx.2010.150318

Hindley, James Philip, Ferreira, Cristina, Jones, Emma, Lauder, Sarah Nicol, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Wynn, Katherine, Betts, Gareth James, Singh, Yogesh, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Dyson, Julian and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2011. Analysis of the T-cell receptor repertoires of tumor-infiltrating conventional and regulatory T cells reveals no evidence for conversion in carcinogen-induced tumors. Cancer Research 71 (3) , pp. 736-746. 10.1158/0008-5472.CAN-10-1797

Ruge, Fiona, Glavini, Aikaterini, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Richards, Hannah E., Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Philpott, Michael P. and Porter, Rebecca ORCID: https://orcid.org/0000-0001-6748-0916 2011. Delineating immune-mediated mechanisms underlying hair follicle destruction in the mouse mutant defolliculated. Journal of Investigative Dermatology 131 (3) , pp. 572-579. 10.1038/jid.2010.379

Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2011. Setting the threshold for extra-thymic differentiation of Foxp3+ Tregs: TGF-β-dependent and T-cell autonomous. European Journal of Immunology 41 (5) , pp. 1218-1220. 10.1002/eji.201141576

Lauder, Sarah Nicol, Smart, Kathryn, Ondondo, B., Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2010. A critical role for interleukin-6 in limiting influenza-induced pathology and generating heterosubtypic immunity [Abstract]. Immunology 131 (S1) , p. 186. 10.1111/j.1365-2567.2010.03390.x

Cuff, Simone ORCID: https://orcid.org/0000-0002-0546-3579, Dolton, Garry Michael, Matthews, Reginald James and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2010. Antigen specificity determines the pro- or antitumoral nature of CD8+ T cells. The Journal of Immunology 184 (2) , pp. 607-614. 10.4049/jimmunol.0804089

Richards, Hannah Catharine, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Jones, Emma, Hindley, James Phillip, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Simon, Anna Katharina and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2010. Novel role of regulatory T cells in limiting early neutrophil responses in skin. Immunology 131 (4) , pp. 583-592. 10.1111/j.1365-2567.2010.03333.x

Gallagher, Kathleen M. E., Lauder, Sarah Nicol, Rees, Ian W., Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 2009. Type I interferon (IFNα) acts directly on human memory CD4+ T cells altering their response to antigen. The Journal of Immunology 183 (5) , pp. 2915-2920. 10.4049/jimmunol.0801607

Baalasubramanian, Sivasankar, Longhi, M. Paula, Gallagher, Kathleen M. E., Betts, Gareth J., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2009. CD59 blockade enhances antigen-specific CD4+ T cell responses in humans: a new target for cancer immunotherapy? The Journal of Immunology 182 (9) , pp. 5203-5207. 10.4049/jimmunol.0804243

Jones, Gareth Wyn, Stumhofer, J. S., Newton, Zarabeth, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Ernst, M., Topley, Nicholas, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Hunter, Catherine, Jenkins, Brian J., Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2008. TL1A/TNFSF15 promotes a STAT1-mediated suppression of IL-17-secreting T-helper cells [Abstract]. Immunology 125 (s1) , p. 62. 10.1111/j.1365-2567.2008.02974.x

Morton, Jonathan, Coles, Barbara, Wright, Kate Louise, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Morrow, Jason D., Terry, Erin S., Anning, Peter, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Dioszeghy, Vincent, Kuhn, Hartmut, Chaitidis, Pavlos, Hobbs, Adrian J., Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2008. Circulating neutrophils maintain physiological blood pressure by suppressing bacteria and IFN -dependent iNOS expression in the vasculature of healthy mice. Blood 111 (10) , pp. 5187-5194. 10.1182/blood-2007-10-117283

Longhi, Maria Paula, Wright, Kate Louise, Lauder, Sarah Nicol, Nowell, Mari Ann, Jones, Gareth Wyn, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2008. Interleukin-6 is crucial for recall of influenza-specific memory cd4+ t cells. PLoS Pathogens 4 (2) , e1000006. 10.1371/journal.ppat.1000006
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Richards, Hannah Catharine, Longhi, Maria Paula, Wright, Kate Louise, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 and Ager, Ann 2008. CD62L (L-Selectin) down-regulation does not affect memory T cell distribution but failure to shed compromises anti-viral immunity. Journal of Immunology 180 (1) , pp. 198-206.

Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 and Simon, A. K. 2008. Positive and negative influences of regulatory T cells on tumour immunity. Oncogene 27 (45) , pp. 5886-5893. 10.1038/onc.2008.269

Boulter, Jonathan M., Schmitz, Nicole, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Bachmann, Martin F. and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2007. Potent T cell agonism mediated by a very rapid TCR/pMHC interaction. European Journal of Immunology 37 (3) , pp. 798-806. 10.1002/eji.200636743

Simon, Anna Katharina, Jones, Emma, Richards, Hannah, Wright, Kate Louise, Betts, Gareth James, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Screaton, Gavin and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2007. Regulatory T cells inhibit Fas ligand induced innate and adaptive tumour immunity. European Journal of Immunology 37 (3) , pp. 758-767. 10.1002/eji.200636593

Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 2007. Regulatory T cells and tumour immunity - observations in mice and men. Immunology 123 (2) , pp. 157-163. 10.1111/j.1365-2567.2007.02748.x

Betts, G., Twohig, Jason Peter, Van den Broek, M., Sierro, S., Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2007. The impact of regulatory T cells on carcinogen-induced sarcogenesis. British Journal of Cancer 96 (12) , pp. 1849-1854. 10.1038/sj.bjc.6603824

Betts, Gareth James, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2007. Reply: forkhead box P3-positive regulatory T cells in immune surveillance and cancer. British Journal of Cancer 97 , pp. 1017-1018. 10.1038/sj.bjc.6603940

Wise, Matthew Peter, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 2006. T-Cell costimulation [Letter]. New England Journal of Medicine 355 (24) , pp. 2594-2595. 10.1056/NEJMc062767

Betts, Gareth James, Clarke, Sarah Louise, Richards, Hannah E., Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2006. Regulating the immune response to tumours. Advanced Drug Delivery Reviews 58 (8) , pp. 948-961. 10.1016/j.addr.2006.05.006

Longhi, M. Paula, Baalasubramanian, Sivasankar, Omidvar, Nader, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2005. Cutting edge: murine CD59a modulates antiviral CD4+ T cell activity in a complement-independent manner. Journal of Immunology 175 (11) , pp. 7098-7102.

Richards, H. E., Simon, A. K., Jones, E., Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Screaton, G. R. and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2005. Inhibition of innate immune responses to tumours by CD4+CD25+ regulatory T cells [Abstract]. Immunology 116 (s1) , p. 36. 10.1111/j.1365-2567.2005.02287.x

Clarke, S. L., Betts, G. J., Wright, K. L., El-Shanawany, Tariq, Plant, A., Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 2005. Analysis of CD4(+)CD25(hi) cells in peripheral blood and lymph nodes of patients with colorectal cancer. Immunology 116 (1) , p. 37. 10.1111/j.1365-2567.2005.02287.x

Jones, Emma, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Dahm-Vicker, Michaela, Cerundolo, Vincenzo, Klenerman, Paul and Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 2003. The influence of macrophage inflammatory protein-1alpha on protective immunity mediated by antiviral cytotoxic T cells. Immunology 109 (1) , pp. 68-75. 10.1046/j.1365-2567.2003.01636.x

Simon, Anna Katharina, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Jones, Emma, Sawitzki, Birgit, Cerundolo, Vincenzo and Screaton, Gavin R. 2002. Fas ligand breaks tolerance to self-antigens and induces tumor immunity mediated by antibodies. Cancer Cell 2 (4) , pp. 315-322. 10.1016/S1535-6108(02)00151-4

Golgher, Denise, Jones, Emma, Powrie, Fiona, Elliot, Tim and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2002. CD25+ regulatory cells uncover immune responses to shared tumour rejection antigens. European Journal of Immunology 32 (11) , pp. 3267-3275. 10.1002/1521-4141(200211)32:11<3267::AID-IMMU3267>3.0.CO;2-1

Bachmann, M. F., Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Linkert, S., Cerundolo, V., Lanzavecchia, A., Kopf, M. and Viola, A. 1999. Developmental regulation of Lck targeting to the CD8 coreceptor controls signaling in naive and memory T cells. Journal of Experimental Medicine 189 (10) , pp. 1521-1530.

Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Hombach, Joachim, Dumrese, Tilman, Rammensee, Hans-Georg, Zinkernagel, Rolf M. and Hengartner, Hans 1998. A protective cytotoxic T cell response to a subdominant epitope is influenced by the stability of the MHC class I/peptide complex and the overall spectrum of viral peptides generated within infected cells. European Journal of Immunology 28 (10) , pp. 3301-3311.

Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Hengartner, H. and Zinkernagel, R. 1998. Hierarchies of antigen-specific cytotoxic T-cell responses. Immunological Reviews 164 , pp. 29-36. 10.1111/j.1600-065X.1998.tb01205.x

Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Schwarz, K., van den Broek, M., Hengartner, H. and Groettrup, M. 1998. The proteasome inhibitor lactacystin prevents the generation of an endoplasmic reticulum leader-derived T cell epitope. Molecular Immunology 35 (10) , pp. 581-591.

Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Dumrese, T., Hengartner, H., Zinkernagel, R. M. and Rammensee, H. G. 1998. Protective immunity does not correlate with the hierarchy of virus-specific cytotoxic T cell responses to naturally processed peptides. Journal of Experimental Medicine 187 (10) , pp. 1647-1657.

Gotch, F., Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 and McMichael, A. 1996. Cytotoxic T cells--protection from disease progression--protection from infection. Immunology Letters 51 (1-2) , pp. 125-128. 10.1016/0165-2478(96)02566-7

Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Cranage, M., Cook, N., Almond, N., Bootman, J., Rud, E., Silvera, P., Dennis, M., Corcoran, T. and Stott, J. 1995. Early suppression of SIV replication by CD8+ nef-specific cytotoxic T cells in vaccinated macaques. Natural Medicines 1 (11) , pp. 1167-1173.

Boyson, J. E,, McAdam, S. N., Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Golos, T. G., Liu, X., Gotch, F. M., Hughes, A. L. and Watkins, D. I. 1995. The MHC E locus in macaques is polymorphic and is conserved between macaques and humans. Immunogenetics 41 (2-3) , pp. 59-68. 10.1007/BF00182314

Rowland-Jones, S., Sutton, J., Ariyoshi, K., Dong, T., Gotch, F., McAdam, S., Whitby, D., Sabally, S., Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 and Corrah, T. 1995. HIV-specific cytotoxic T-cells in HIV-exposed but uninfected Gambian women. Natural Medicines 1 (1) , pp. 59-64.

Gotch, F., McAdam, S. N., Allsopp, C. E., Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Elvin, J., Kieny, M. P., Hill, A. V., McMichael, A. J. and Whittle, H. C. 1993. Cytotoxic T cells in HIV2 seropositive Gambians. Identification of a virus-specific MHC-restricted peptide epitope. The Journal of Immunology 151 (6) , pp. 3361-3369.

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