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The search for antivirals to treat alphavirus infections

Bassetto, Marcella and Brancale, Andrea ORCID: 2021. The search for antivirals to treat alphavirus infections. Annual Reports in Medicinal Chemistry, Vol. 57. Coronaviruses and other Novel Antiviral Targets, Elsevier, pp. 133-151. (10.1016/bs.armc.2021.09.002)

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Alphaviruses are a group of viruses responsible for a variety of emerging and re-emerging human diseases. Although they do not generally cause life-threatening illnesses, they can lead to debilitating and chronic conditions. However, no specific antiviral, nor a vaccine, is available for the treatment of any alphavirus infection. This clearly represents an important unmet medical need, and there is a very active research community trying to respond to this need, by working towards the design and development on novel anti-alphavirus compounds. In this chapter, we will look at the most recent strategies used by the researchers in the field to identify novel, much needed, antivirals.

Item Type: Book Section
Date Type: Publication
Status: Published
Schools: Pharmacy
Publisher: Elsevier
ISBN: 9780323915113
Last Modified: 06 Jan 2024 05:10

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