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Number of items: 56.

Clarke, Rebekah, Palazzo, Giuseppe, Ruzicka, Jiri, Ferla, Salvatore and Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 2026. Computer-aided drug discovery: historical foundations, practical AI tools, and emerging ethical considerations. Frontiers in Pharmacology 17 , 1866562. 10.3389/fphar.2026.1866562
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Wasson, Samantha Rae, Flude, Ben Matthew, Salerno, Martina, Jung, Kie Hoon, Padalino, Gilda, Ferla, Salvatore, Roche-Dugmore, Dylan Joseph, Bott, Connor W, Brancale, Andrea, Gowen, Brian B. and Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 2026. Computer-aided discovery of small-molecule inhibitors of pathogenic new world arenavirus entry and replication. ACS Infectious Diseases 12 (6) , pp. 2046-2059. 10.1021/acsinfecdis.6c00138
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Palazzo, Giuseppe, Ferla, Salvatore and Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 2025. Computer-aided approaches for human norovirus drug discovery: a comprehensive review. Expert Opinion on Drug Discovery 20 (12) , pp. 1589-1606. 10.1080/17460441.2025.2601118
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Meades, Jessica L., Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868, Staiculescu, Marius C., Swaminath, Gayathri and Fountain, Samuel J. 2025. Structure–activity relationship of the allosteric effects of ivermectin at human P2X4 and GABA A receptors. British Journal of Pharmacology 182 (21) , pp. 5286-5302. 10.1111/bph.70121
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Queirós-Reis, Luís, Kaarbo, Mari, Al-Baldawi, Huda, Alvites, Rui, Maurício, Ana Colette, Brancale, Andrea, Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 and Mesquita, João R. 2025. In silico discovery of a novel antiviral scaffold for SARS-CoV-2 targeting the spike glycoprotein through the fatty acid binding pocket. ACS Omega 10 (23) , pp. 24117-24132. 10.1021/acsomega.4c10519
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Felippe, Igor S. A., Babbage, Thalia L., Shaheen, Rajaa, Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868, Fan, Jui-Lin, Pauza, Audrys, Gold, Olivia, Thakkar, Pratik, Dawes, Matthew, Bates, Melissa L., McBryde, Fiona, Fountain, Samuel J., Fisher, James P. and Paton, Julian F. R. 2025. Vitamin B6 (pyridoxal 5’ phosphate) antagonizes carotid body P2X3 receptors in hypertension. Cardiovascular Research 122 (2) , pp. 285-296. 10.1093/cvr/cvaf195
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Ng, Mei Ying, Song, Zhi Jian, Tan, Choon Hong, Bassetto, Marcella and Hagen, Thilo 2024. Structural investigations on the mitochondrial uncouplers niclosamide and FCCP. FEBS Open Bio 14 (7) , pp. 1057-1071. 10.1002/2211-5463.13817
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Ng, Mei Ying, Song, Zhi Jian, Venkatesan, Gopalakrishnan, Rodriguez-Cuenca, Sergio, West, James A., Yang, Shili, Tan, Choon Hong, Ho, Paul Chi-Lui, Griffin, Julian L., Vidal-Puig, Antonio, Bassetto, Marcella and Hagen, Thilo 2024. Conjugating uncoupler compounds with hydrophobic hydrocarbon chains to achieve adipose tissue selective drug accumulation. Scientific Reports 14 (1) , 4932. 10.1038/s41598-024-54466-2
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Queirós-Reis, Luís, Mesquita, João R., Brancale, Andrea and Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 2023. Exploring the fatty acid binding pocket in the SARS-CoV-2 spike protein - confirmed and potential ligands. Journal of Chemical Information and Modeling 63 (23) , 7282–7298. 10.1021/acs.jcim.3c00803
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Gushchina, Valeriya, Kupper, Nadja, Schwarzkopf, Michael, Frisch, Gitta, Piatek, Karina, Aigner, Cornelia, Michel, Alexandra, Schueffl, Hemma, Iamartino, Luca, Elajnaf, Taha, Manhardt, Teresa, Vlasaty, Andrea, Heffeter, Petra, Bassetto, Marcella, Kállay, Enikö and Schepelmann, Martin 2023. The calcium-sensing receptor modulates the prostaglandin E 2 pathway in intestinal inflammation. Frontiers in Pharmacology 14 , 1151144. 10.3389/fphar.2023.1151144
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Salerno, Martina, Varricchio, Carmine ORCID: https://orcid.org/0000-0002-1673-4768, Bevilacqua, Federica, Jochmans, Dirk, Neyts, Johan, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Ferla, Salvatore and Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 2023. Rational design of novel nucleoside analogues reveals potent antiviral agents for EV71. European Journal of Medicinal Chemistry 246 , 114942. 10.1016/j.ejmech.2022.114942
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Giancotti, Gilda, Nannetti, Giulio ORCID: https://orcid.org/0000-0003-3227-1537, Padalino, Gilda, Landini, Martina, Santos-Ferreira, Nanci, Van Dycke, Jana, Naccarato, Valentina, Patel, Usheer, Silvestri, Romano, Neyts, Johan, Gozalbo-Rovira, Roberto, Rodríguez-Díaz, Jésus, Rocha-Pereira, Joana, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Ferla, Salvatore ORCID: https://orcid.org/0000-0002-5918-9237 and Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 2022. Structural investigations on novel non-nucleoside inhibitors of human norovirus polymerase. Viruses 15 (1) , 74. 10.3390/v15010074
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Picarazzi, Francesca, Zuanon, Marika, Pasqualetto, Gaia, Cammarone, Silvia, Romeo, Isabella, Young, Mark T. ORCID: https://orcid.org/0000-0002-9615-9002, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 and Mori, Mattia 2022. Identification of small molecular chaperones binding p23h mutant opsin through an in silico structure-based approach. Journal of Chemical Information and Modeling 62 (22) , pp. 5794-5805. 10.1021/acs.jcim.2c01040
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Menendez-Gonzalez, Juan Bautista, Strange, Kathryn E., Bassetto, Marcella, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 and Ferla, Salvatore 2022. Ligand-based discovery of a novel GATA2 inhibitor targeting acute myeloid leukemia cells. Frontiers In Drug Discovery 2 , 1013229. 10.3389/fddsv.2022.1013229
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Gill, Martin R., Jarman, Paul J., Hearnden, Vanessa, Fairbanks, Simon D., Bassetto, Marcella, Palmer, John, Ayscough, Kathryn R., Thomas, Jim A. and Smythe, Carl 2022. A ruthenium(II) polypyridyl complex disrupts actin cytoskeleton assembly and blocks cytokinesis. Angewandte chemie-international edition 61 (27) , e202117449. 10.1002/anie.202117449
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Hucke, Friederike I. L., Bestehorn-Willmann, Malena, Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Zanetta, Paola and Bugert, Joachim J. 2022. CHIKV strains Brazil (wt) and Ross (lab-adapted) differ with regard to cell host range and antiviral sensitivity and show CPE in human glioblastoma cell lines U138 and U251. Virus Genes 58 , pp. 188-202. 10.1007/s11262-022-01892-x
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Pasqualetto, Gaia, Pileggi, Elisa, Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Varricchio, Carmine ORCID: https://orcid.org/0000-0002-1673-4768, Rozanowska, Malgorzata ORCID: https://orcid.org/0000-0003-2913-8954, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 2021. Ligand-based rational design, synthesis and evaluation of novel potential chemical chaperones for opsin. European Journal of Medicinal Chemistry 226 , 113841. 10.1016/j.ejmech.2021.113841
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Padalino, Gilda, El-Sakkary, Nelly, Liu, Lawrence J., Liu, Chenxi, Harte, Danielle S.G., Barnes, Rachel E., Sayers, Edward ORCID: https://orcid.org/0000-0002-2621-1119, Forde-Thomas, Josephine, Whiteland, Helen, Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868, Ferla, Salvatore, Johnson, George, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905, Caffrey, Conor R., Chalmers, Iain, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and Hoffmann, Karl F. 2021. Anti-schistosomal activities of quinoxaline-containing compounds: From hit identification to lead optimisation. European Journal of Medicinal Chemistry 226 , 113823. 10.1016/j.ejmech.2021.113823
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Bassetto, Marcella and Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 2021. The search for antivirals to treat alphavirus infections. Annual Reports in Medicinal Chemistry, Vol. 57 Coronaviruses and other Novel Antiviral Targets, Elsevier, pp. 133-151. (10.1016/bs.armc.2021.09.002)

Queirós-Reis, Luís, Gomes da Silva, Priscilla, Gonçalves, José, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Bassetto, Marcella and Mesquita, João R. 2021. SARS-CoV-2 virus-host interaction: currently available structures and implications of variant emergence on infectivity and immune response. International Journal of Molecular Sciences 22 (19) , 10836. 10.3390/ijms221910836
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Schepelmann, Martin, Kupper, Nadja, Sladczyk, Marta, Mansfield, Bethan, Manhardt, Teresa, Piatek, Karina, Iamartino, Luca, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Kariuki, Benson M. ORCID: https://orcid.org/0000-0002-8658-3897, Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 and Kallay, Enikö 2021. Stereo-specific modulation of the extracellular calcium-sensing receptor in colon cancer cells. International Journal of Molecular Sciences 22 (18) , 10124. 10.3390/ijms221810124
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Ferla, Salvatore ORCID: https://orcid.org/0000-0002-5918-9237, Varricchio, Carmine ORCID: https://orcid.org/0000-0002-1673-4768, Knight, William, Ho, Pui Kei, Saporito, Fabiana, Tropea, Beatrice, Fagan, Giulio, Flude, Ben Matthew, Bevilacqua, Federica, Santos-Ferreira, Nanci, Van Dycke, Jana, Neyts, Johan, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Rocha-Pereira, Joana and Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 2021. Structure-activity relationship studies on novel antiviral agents for norovirus infections. Microorganisms 9 (9) , 1795. 10.3390/microorganisms9091795
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Flude, Ben M., Nannetti, Giulio ORCID: https://orcid.org/0000-0003-3227-1537, Mitchell, Paige, Compton, Nina, Richards, Chloe, Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Ferla, Salvatore ORCID: https://orcid.org/0000-0002-5918-9237 and Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 2021. Targeting the complement serine protease MASP-2 as a therapeutic strategy for coronavirus infections. Viruses 13 (2) , 312. 10.3390/v13020312
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ter Horst, Sebastiaan, Fernandez-Garcia, Yaiza, Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868, Günther, Stephan, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Neyts, Johan and Rocha-Pereira, Joana 2020. Enhanced efficacy of endonuclease inhibitor baloxavir acid against orthobunyaviruses when used in combination with ribavirin. Journal of Antimicrobial Chemotherapy 75 (11) , pp. 3189-3193. 10.1093/jac/dkaa337
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Fernández-García, Yaiza, Horst, Sebastiaan ter, Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Neyts, Johan, Rogolino, Dominga, Sechi, Mario, Carcelli, Mauro, Günther, Stephan and Rocha-Pereira, Joana 2020. Diketo acids inhibit the cap-snatching endonuclease of several Bunyavirales. Antiviral Research 183 , 104947. 10.1016/j.antiviral.2020.104947
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Thames, Joy E., Waters, Charles D., Valle, Coralie, Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868, Aouadi, Wahiba, Martin, Baptiste, Selisko, Barbara, Falat, Arissa, Coutard, Bruno, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Canard, Bruno, Decroly, Etienne and Seley-Radtke, Katherine L. 2020. Synthesis and biological evaluation of novel flexible nucleoside analogues that inhibit flavivirus replication in vitro. Bioorganic and Medicinal Chemistry 28 (22) , 115713. 10.1016/j.bmc.2020.115713
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Bauer, Lisa, Manganaro, Roberto, Zonsics, Birgit, Hurdiss, Daniel L., Zwaagstra, Marleen, Donselaar, Tim, Welter, Naemi G. E., van Kleef, Regina G. D. M., Lopez, Moira Lorenzo, Bevilacqua, Federica, Raman, Thamidur, Ferla, Salvatore ORCID: https://orcid.org/0000-0002-5918-9237, Bassetto, Marcella, Neyts, Johan, Strating, Jeroen R. P. M., Westerink, Remco H. S., Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and van Kuppeveld, Frank J. M. 2020. Rational design of highly potent broad-spectrum enterovirus inhibitors targeting the nonstructural protein 2C. PLOS Biology 18 (11) , e3000904. 10.1371/journal.pbio.3000904
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Pasqualetto, Gaia, Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Varricchio, Carmine ORCID: https://orcid.org/0000-0002-1673-4768, Pileggi, Elisa, Khogali, Caroline, Morgan, Siân R., Boostrom, Ian, Rozanowska, Malgorzata ORCID: https://orcid.org/0000-0003-2913-8954, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Ferla, Salvatore ORCID: https://orcid.org/0000-0002-5918-9237 and Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 2020. Computational studies towards the identification of novel rhodopsin-binding compounds as chemical chaperones for misfolded opsins. Molecules 25 (21) , 4904. 10.3390/molecules25214904
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Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868, Cima, Cecilia M., Basso, Mattia, Salerno, Martina, Schwarze, Frank, Friese, Daniela, Bugert, Joachim J. and Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 2020. Novel nucleoside analogues as affective antiviral agents for Zika virus infections. Molecules 25 (20) , 4813. 10.3390/molecules25204813
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Bugert, J. J., Hucke, F., Zanetta, P., Bassetto, Marcella and Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 2020. Antivirals in medical biodefense. Virus Genes 56 (2) , pp. 150-167. 10.1007/s11262-020-01737-5

Ferla, Salvatore ORCID: https://orcid.org/0000-0002-5918-9237, Manganaro, Roberto, Benato, Sara, Paulissen, Jasmine, Neyts, Johan, Jochmans, Dirk, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 2020. Rational modifications, synthesis and biological evaluation of new potential antivirals for RSV designed to target the M2-1 protein. Bioorganic and Medicinal Chemistry 28 (8) , 115401. 10.1016/j.bmc.2020.115401
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Elajnaf, Taha, Iamartino, Luca, Mesteri, Ildiko, Mueller, Christian, Bassetto, Marcella, Manhardt, Teresa, Baumgartner-Parzer, Sabina, Kallay, Enikoe and Schepelmann, Martin 2019. Nutritional and pharmacological targeting of the calcium-sensing receptor influences chemically induced colitis in mice. Nutrients 11 (12) , 3072. 10.3390/nu11123072
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Giancotti, Gilda, Rigo, Ilaria, Pasqualetto, Gaia, Young, Mark T. ORCID: https://orcid.org/0000-0002-9615-9002, Neyts, Johan, Rocha-Pereira, Joana, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Ferla, Salvatore ORCID: https://orcid.org/0000-0002-5918-9237 and Bassetto, Marcella 2019. A new antiviral scaffold for human norovirus identified with computer-aided approaches on the viral polymerase. Scientific Reports 9 (1) , 18413. 10.1038/s41598-019-54903-7
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Pertusati, Fabrizio ORCID: https://orcid.org/0000-0003-4532-9101, Ferla, Salvatore ORCID: https://orcid.org/0000-0002-5918-9237, Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Kandil, Sahar ORCID: https://orcid.org/0000-0003-1806-9623, Westwell, Andrew D. ORCID: https://orcid.org/0000-0002-5166-9236 and McGuigan, Christopher 2019. A new series of bicalutamide, enzalutamide and enobosarm derivatives carrying pentafluorosulfanyl (SF5) and pentafluoroethyl (C2F5) substituents: Improved antiproliferative agents against prostate cancer. European Journal of Medicinal Chemistry 180 , pp. 1-14. 10.1016/j.ejmech.2019.07.001
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Pasqualetto, Gaia, Pileggi, Elisa, Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Heard, Charles ORCID: https://orcid.org/0000-0001-9703-9777, Young, Mark Thomas ORCID: https://orcid.org/0000-0002-9615-9002, Rozanowska, Malgorzata B. ORCID: https://orcid.org/0000-0003-2913-8954, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 2019. Novel small-molecule chaperones to overcome opsin misfolding, mistrafficking and aggregation in retinal blinding diseases [Abstract]. Investigative Ophthalmology & Visual Science 60 (9)

Pileggi, Elisa, Pasqualetto, Gaia, Rozanowska, Malgorzata ORCID: https://orcid.org/0000-0003-2913-8954, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 2019. Development of novel treatments against inherited blinding diseases Retinitis pigmentosa and Leber's congenital amaurosis [Abstract]. Abstracts of Papers of the American Chemical Society 257 , 318.

Bassetto, Marcella, Van Dycke, Jana, Neyts, Johan, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and Rocha-Pereira, Joana 2019. Targeting the viral polymerase of diarrhea-causing viruses as a strategy to develop a single broad-spectrum antiviral therapy. Viruses 11 (2) , 173. 10.3390/v11020173
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Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 and Slusarczyk, Magdalena ORCID: https://orcid.org/0000-0002-4707-7190 2019. Therapeutic use of fluorinated nucleosides – progress in patents. Pharmaceutical Patent Analyst 7 (6) , p. 277. 10.4155/ppa-2018-0028
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Giancotti, Gilda, Cancellieri, Michela, Balboni, Andrea, Giustiniano, Mariateresa, Novellino, Ettore, Delang, Leen, Neyts, Johan, Leyssen, Pieter, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 2018. Rational modifications on a benzylidene-acrylohydrazide antiviral scaffold, synthesis and evaluation of bioactivity against Chikungunya virus. European Journal of Medicinal Chemistry 149 , pp. 56-68. 10.1016/j.ejmech.2018.02.054
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Ferla, Salvatore ORCID: https://orcid.org/0000-0002-5918-9237, Netzler, Natalie E., Ferla, Sebastiano ORCID: https://orcid.org/0000-0002-5918-9237, Veronese, Sofia, Tuipulotu, Daniel Enosi, Guccione, Salvatore, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, White, Peter A. and Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 2018. In silico screening for human norovirus antivirals reveals a novel non-nucleoside inhibitor of the viral polymerase. Scientific Reports 8 (4129) , 4129. 10.1038/s41598-018-22303-y
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Tardugno, Roberta, Giancotti, Gilda, De Burghgraeve, Tine, Delang, Leen, Neyts, Johan, Leyssen, Pieter, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 2018. Design, synthesis and evaluation against Chikungunya virus of novel small-molecule antiviral agents. Bioorganic and Medicinal Chemistry 26 (4) , pp. 869-874. 10.1016/j.bmc.2018.01.002
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Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868, Ferla, Salvatore ORCID: https://orcid.org/0000-0002-5918-9237, Giancotti, Gilda, Pertusati, Fabrizio ORCID: https://orcid.org/0000-0003-4532-9101, Westwell, Andrew D. ORCID: https://orcid.org/0000-0002-5166-9236, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and McGuigan, Christopher 2017. Rational design and synthesis of novel phenylsulfonyl-benzamides as anti-prostate cancer agents. MedChemComm 8 (7) , pp. 1414-1420. 10.1039/C7MD00164A
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Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Shailubhai, Kunwar, Ferla, Salvatore ORCID: https://orcid.org/0000-0002-5918-9237, Ricci, Antonio, Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 and Jacob, Gary S. 2017. Therapeutically targeting guanylate cyclase-C: computational modeling of plecanatide, a uroguanylin analog. Pharmacology Research & Perspectives 5 (2) , e00295. 10.1002/prp2.295
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Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868, Leyssen, Pieter, Neyts, Johan, Yerukhimovich, Mark M., Frick, David N. and Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 2017. Shape-based virtual screening, synthesis and evaluation of novel pyrrolone derivatives as antiviral agents against HCV. Bioorganic & Medicinal Chemistry Letters 27 (4) , pp. 936-940. 10.1016/j.bmcl.2016.12.087
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Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868, Leyssen, Pieter, Neyts, Johan, Yerukhimovich, Mark M., Frick, David N., Courtney-Smith, Matthew and Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 2017. In silico identification, design and synthesis of novel piperazine-based antiviral agents targeting the hepatitis C virus helicase. European Journal of Medicinal Chemistry 125 , pp. 1115-1131. 10.1016/j.ejmech.2016.10.043
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Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868, Massarotti, Alberto, Coluccia, Antonio and Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 2016. Structural biology in antiviral drug discovery. Current Opinion in Pharmacology 30 , pp. 116-130. 10.1016/j.coph.2016.08.014
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Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868, Ferla, Salvatore ORCID: https://orcid.org/0000-0002-5918-9237, Pertusati, Fabrizio ORCID: https://orcid.org/0000-0003-4532-9101, Kandil, Sahar ORCID: https://orcid.org/0000-0003-1806-9623, Westwell, Andrew ORCID: https://orcid.org/0000-0002-5166-9236, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X 2016. Design and synthesis of novel bicalutamide and enzalutamide derivatives as antiproliferative agents for the treatment of prostate cancer. European Journal of Medicinal Chemistry 118 , pp. 230-243. 10.1016/j.ejmech.2016.04.052
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Ferla, Salvatore ORCID: https://orcid.org/0000-0002-5918-9237, Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868, Pertusati, Fabrizio ORCID: https://orcid.org/0000-0003-4532-9101, Kandil, Sahar ORCID: https://orcid.org/0000-0003-1806-9623, Westwell, Andrew D. ORCID: https://orcid.org/0000-0002-5166-9236, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X 2016. Rational design and synthesis of novel anti-prostate cancer agents bearing a 3,5-bis-trifluoromethylphenyl moiety. Bioorganic and Medicinal Chemistry Letters 26 (15) , pp. 3636-3640. 10.1016/j.bmcl.2016.06.001
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Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868, Leyssen, Pieter, Neyts, Johan, Yerukhimovich, Mark M., Frick, David N. and Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 2016. Computer-aided identification, synthesis and evaluation of substituted thienopyrimidines as novel inhibitors of HCV replication. European Journal of Medicinal Chemistry 10.1016/j.ejmech.2016.07.035
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Cancellieri, Michela, Bassetto, Marcella, Widjaja, Ivy, van Kuppeveld, Frank, de Haan, Cornelis A.M. and Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 2015. In silico structure-based design and synthesis of novel anti-RSV compounds. Antiviral Research 122 , pp. 46-50. 10.1016/j.antiviral.2015.08.003
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Wang, Xiaozhao, Liu, Li, Huang, Longchuan, Herbst-Robinson, Katie, Cornec, Anne-Sophie, James, Michael J., Sugiyama, Shimpei, Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Trojanowski, John Q., Lee, Virginia M.-Y., Smith, Amos B., Brunden, Kurt R. and Ballatore, Carlo 2014. Potent, long-acting cyclopentane-1,3-Dione Thromboxane (A2)-receptor antagonists. ACS Medicinal Chemistry Letters 5 (9) , pp. 1015-1020. 10.1021/ml5002085
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Romagnoli, Romeo, Baraldi, Pier Giovanni, Lopez-Cara, Carlota, Preti, Delia, Aghazadeh Tabrizi, Mojgan, Balzarini, Jan, Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Fu, Xian-Hua, Gao, Yang, Li, Jun, Zhang, Su-Zhan, Hamel, Ernest, Bortolozzi, Roberta, Basso, Giuseppe and Viola, Giampietro 2013. Concise synthesis and biological evaluation of 2-aroyl-5-amino benzo[b]thiophene derivatives as a novel class of potent antimitotic agents. Journal of Medicinal Chemistry 56 (22) , pp. 9296-9309. 10.1021/jm4013938

Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868, De Burghgraeve, Tine, Delang, Leen, Massarotti, Alberto, Coluccia, Antonio, Zonta, Nicola, Gatti, Valerio, Colombano, Giampiero, Sorba, Giovanni, Silvestri, Romano, Tron, Gian Cesare, Neyts, Johan, Leyssen, Pieter and Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 2013. Computer-aided identification, design and synthesis of a novel series of compounds with selective antiviral activity against chikungunya virus. Antiviral Research 98 (1) , pp. 12-18. 10.1016/j.antiviral.2013.01.002

Romagnoli, Romeo, Baraldi, Pier Giovanni, Kimatrai Salvador, Maria, Preti, Delia, Aghazadeh Tabrizi, Mojgan, Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Hamel, Ernest, Castagliuolo, Ignazio, Bortolozzi, Roberta, Basso, Giuseppe and Viola, Giampietro 2013. Synthesis and biological evaluation of 2-(alkoxycarbonyl)-3-anilinobenzo[b]thiophenes and thieno[2,3-b]pyridines as new potent anticancer agents. Journal of Medicinal Chemistry 56 (6) , pp. 2606-2618. 10.1021/jm400043d

Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 2013. Computer-aided design, synthesis and evaluation of potential anti-HCV agents. PhD Thesis, Cardiff University.
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Romagnoli, Romeo, Baraldi, Pier Giovanni, Salvador, Maria Kimatrai, Camacho, M. Encarnacion, Preti, Delia, Tabrizi, Mojgan Aghazadeh, Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Hamel, Ernest, Bortolozzi, Roberta, Basso, Giuseppe and Viola, Giampietro 2012. Synthesis and biological evaluation of 2-substituted-4-(3′,4′,5′-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents. Bioorganic & Medicinal Chemistry 20 (24) , pp. 7083-7094. 10.1016/j.bmc.2012.10.001

This list was generated on Wed Sep 16 03:15:55 2026 BST.


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