| Li, Zeyang, Pollard, Stuart, Smith, Gemma, Deshmukh, Subodh and Ding, Ziyun
      2024.
      
      Biomechanical analysis of combi-hole locking compression plate during fracture healing: A numerical study of screw configuration.
      Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine
      238
      
        (3)
      
      , pp. 313-323.
      
      10.1177/09544119241229157   | 
| ![li-et-al-2024-biomechanical-analysis-of-combi-hole-locking-compression-plate-during-fracture-healing-a-numerical-study.pdf [thumbnail of li-et-al-2024-biomechanical-analysis-of-combi-hole-locking-compression-plate-during-fracture-healing-a-numerical-study.pdf]](https://orca.cardiff.ac.uk/style/images/fileicons/application_pdf.png) | PDF
 - Published Version Available under License Creative Commons Attribution Non-commercial. Download (4MB) | 
Abstract
Locking compression plates (LCPs) have become a widely used option for treating femur bone fractures. However, the optimal screw configuration with combi-holes remains a subject of debate. The study aims to create a time-dependent finite element (FE) model to assess the impacts of different screw configurations on LCP fixation stiffness and healing efficiency across four healing stages during a complete fracture healing process. To simulate the healing process, we integrated a time-dependent callus formation mechanism into a FE model of the LCP with combi-holes. Three screw configuration parameters, namely working length, screw number, and screw position, were investigated. Increasing the working length negatively affected axial stiffness and healing efficiency (p < 0.001), while screw number or position had no significant impact (p > 0.01). The time-dependent model displayed a moderate correlation with the conventional time-independent model for axial stiffness and healing efficiency (ρ ≥ 0.733, p ≤ 0.025). The highest healing efficiency (95.2%) was observed in screw configuration C125 during the 4–8-week period. The results provide insights into managing fractures using LCPs with combi-holes over an extended duration. Under axial compressive loading conditions, the use of the C125 screw configuration can enhance callus formation during the 4–12-week period for transverse fractures. When employing the C12345 configuration, it becomes crucial to avoid overconstraint during the 4–8-week period.
| Item Type: | Article | 
|---|---|
| Date Type: | Publication | 
| Status: | Published | 
| Schools: | Schools > Engineering | 
| Publisher: | SAGE Publications | 
| ISSN: | 0954-4119 | 
| Date of First Compliant Deposit: | 5 March 2024 | 
| Last Modified: | 29 Apr 2024 13:40 | 
| URI: | https://orca.cardiff.ac.uk/id/eprint/166844 | 
Actions (repository staff only)
|  | Edit Item | 

 
							

 Altmetric
 Altmetric Altmetric
 Altmetric