OP-07 Retinal and cortical vascular function across the menstrual cycle

Wright, Melissa E. ORCID: https://orcid.org/0000-0002-2744-4504, Crofts, Andrew, Davies, Saajan, Chandler, Hannah, Driver, Ian ORCID: https://orcid.org/0000-0001-6815-0134, Germuska, Michael ORCID: https://orcid.org/0000-0003-0580-4350, Giarratano, Ylenia, Bernabeu, Miguel O., Terry, Louise, Steventon, Jessica J. and Murphy, Kevin ORCID: https://orcid.org/0000-0002-6516-313X 2024. OP-07 Retinal and cortical vascular function across the menstrual cycle. Presented at: Women in Vision UK Winter Meeting 2023, Cambridge, UK, 12 December 2023. BMJ Open Ophthalmology. , vol.9 10.1136/bmjoo-2024-WVUK.7

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Abstract

Introduction Oestrogen has a protective effect against neurodegenerative conditions, including glaucoma and dementia. Animal models suggest that oestrogen has a vasodilatory effect, which is a possible mechanism for this. However, the full influence of oestrogen on specific cerebrovascular functions is unclear. Aims This study aims to investigate the influence of hormonal fluctuations across a healthy menstrual cycle on measures of retinal and cortical vascular functioning. Methods 27 menstruating participants (age mean[SD]=22.94[3.52] years) completed a testing session during the early-follicular, late-follicular, and mid-luteal phase of their menstrual cycle. Bloods were taken to measure circulating hormones.

Item Type:	Conference or Workshop Item (Paper)
Date Type:	Publication
Status:	Published
Schools:	Physics and Astronomy Medicine Psychology Cardiff University Brain Research Imaging Centre (CUBRIC)
Funders:	Wellcome Trust
Date of First Compliant Deposit:	12 June 2024
Last Modified:	04 Jul 2024 15:29
URI:	https://orca.cardiff.ac.uk/id/eprint/169049

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