Macrophage heterogeneity and acute inflammation

Liddiard, Kate ORCID: https://orcid.org/0000-0002-0953-1997, Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Davies, Luke Cynlais, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421 2011. Macrophage heterogeneity and acute inflammation. European Journal of Immunology 41 (9) , pp. 2503-2508. 10.1002/eji.201141743

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Abstract

In this Viewpoint, we concentrate on the aspects of macrophage biology that we believe are fundamental for an appropriate contextual understanding of macrophage function during acute inflammation. These are the different origins of macrophage populations (and the implications of this for the renewal of these populations in the adult); and the impact of specific homeostatic or disease-associated microenvironments upon cellular heterogeneity, activation and effector functions.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Schools > Biosciences Schools > Medicine Research Institutes & Centres > Systems Immunity Research Institute (SIURI)
Subjects:	R Medicine > R Medicine (General)
Uncontrolled Keywords:	Cellular activation ; Homeostasis ; Inflammation ; Macrophages
Publisher:	John Wiley & Sons
ISSN:	0014-2980
Last Modified:	05 Nov 2022 15:11
URI:	https://orca.cardiff.ac.uk/id/eprint/22558

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