Corvin, A., Craddock, Nicholas John  ORCID: https://orcid.org/0000-0003-2171-0610 and Sullivan, P. F.
2010.
Genome-wide association studies: a primer.
Psychological Medicine
40
(7)
, pp. 1063-1077.
10.1017/S0033291709991723
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Abstract
There have been nearly 400 genome-wide association studies (GWAS) published since 2005. The GWAS approach has been exceptionally successful in identifying common genetic variants that predispose to a variety of complex human diseases and biochemical and anthropometric traits. Although this approach is relatively new, there are many excellent reviews of different aspects of the GWAS method. Here, we provide a primer, an annotated overview of the GWAS method with particular reference to psychiatric genetics. We dissect the GWAS methodology into its components and provide a brief description with citations and links to reviews that cover the topic in detail.
| Item Type: | Article |
|---|---|
| Date Type: | Publication |
| Status: | Published |
| Schools: | Schools > Psychology Schools > Medicine Research Institutes & Centres > MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG) |
| Subjects: | R Medicine > R Medicine (General) |
| Uncontrolled Keywords: | Genome-wide association study; psychiatric genetics; review |
| Additional Information: | Pdf uploaded in accordance with publisher's policy at http://www.sherpa.ac.uk/romeo/issn/0033-2917/ (accessed 25/02/2014). |
| Publisher: | Cambridge University Press |
| ISSN: | 0033-2917 |
| Date of First Compliant Deposit: | 30 March 2016 |
| Last Modified: | 11 May 2023 17:19 |
| URI: | https://orca.cardiff.ac.uk/id/eprint/29780 |
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