Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Homology Modelling of Human E1 Ubiquitin Activating Enzyme

Brahemi, Ghali, Burger, A. M., Westwell, Andrew ORCID: and Brancale, Andrea ORCID: 2010. Homology Modelling of Human E1 Ubiquitin Activating Enzyme. Letters in Drug Design & Discovery 7 (1) , pp. 57-62. 10.2174/157018010789869316

[thumbnail of Westwell2010.pdf]
Download (9MB) | Preview


Human E1 is a key player in protein ubiquitination, however the E1 structure is not available. In this paper, we describe the derivation of a human E1 structure using molecular modelling based on the crystal structure of S. cerevisiae E1 and M. Musculus E1. Key interactions between our E1 model and ubiquitin are also discussed.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Pharmacy
Subjects: R Medicine > RS Pharmacy and materia medica
Uncontrolled Keywords: ubiquitination, human E1, ubiquitin activating enzyme, homology modelling
Publisher: PubMed Central
ISSN: 1570-1808
Last Modified: 05 Jan 2024 05:54

Citation Data

Cited 5 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item


Downloads per month over past year

View more statistics