System Dynamics modeling of Chlamydia infection for screening intervention planning and cost-benefit estimation

Evenden, Dave, Harper, Paul Robert ORCID: https://orcid.org/0000-0001-7894-4907, Brailsford, Sally C. and Harindra, Veerakathy 2005. System Dynamics modeling of Chlamydia infection for screening intervention planning and cost-benefit estimation. IMA Journal of Management Mathematics 16 (3) , pp. 265-279. 10.1093/imaman/dpi022

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Abstract

Genital Chlamydia trachomatis infection is the most common sexually transmitted infection in the UK. It constitutes a major public health problem given that the majority of infections are asymptomatic which can lead to serious long-term medical consequences if not treated. This paper describes a System Dynamics model for capturing Chlamydia infection dynamics within a population, incorporating the behaviour of different risk groups, and provides a cost-benefit study for screening using data collected from the Department of Health opportunistic Chlamydia screening programme in Portsmouth. Furthermore, we demonstrate that high-risk groups are key in determining the overall infection dynamics of the system, and quantify screening rates required to manage infection prevalence within the wider population.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Schools > Mathematics
Subjects:	Q Science > QA Mathematics
Publisher:	Oxford University Press
ISSN:	1471-678X
Last Modified:	31 Oct 2022 09:21
URI:	https://orca.cardiff.ac.uk/id/eprint/80678

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