Phesse, Toby  ORCID: https://orcid.org/0000-0001-9568-4916 and Sansom, Owen J.
2013.
Responding to R-spondin: slit2 potentiates intestinal regeneration.
Cell Stem Cell
13
, pp. 512-514.
10.1016/j.stem.2013.10.006
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Official URL: http://dx.doi.org/10.1016/j.stem.2013.10.006
Abstract
Gastrointestinal toxicity of chemoradiotherapy treatment in late-stage cancer patients limits tolerable doses and effectiveness of treatments. Zhou and colleagues in Nature ( Zhou et al., 2013) suggest that activating Robo/Slit signaling in concert with R-Spondin potentiates Wnt signaling in intestinal stem cells and drives successful intestinal regeneration and recovery.
| Item Type: | Article |
|---|---|
| Date Type: | Publication |
| Status: | Published |
| Schools: | Schools > Biosciences Research Institutes & Centres > European Cancer Stem Cell Research Institute (ECSCRI) |
| Subjects: | Q Science > QH Natural history > QH426 Genetics |
| Publisher: | Elsevier |
| Date of First Compliant Deposit: | 21 June 2016 |
| Last Modified: | 01 Jul 2023 07:42 |
| URI: | https://orca.cardiff.ac.uk/id/eprint/91567 |
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