Pertusati, Fabrizio ORCID: https://orcid.org/0000-0003-4532-9101, Nutz, Eva, Kariuki, Benson ORCID: https://orcid.org/0000-0002-8658-3897 and Coogan, Michael P.
2017.
Synthesis and substrate-controlled reactions of 2,2′-unsaturated biquinazolinones.
Tetrahedron
73
(1)
, pp. 55-63.
10.1016/j.tet.2016.11.060
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Official URL: http://dx.doi.org/10.1016/j.tet.2016.11.060
Abstract
A series of BiQuinazolinones bearing either double or triple bonds in their lateral chains have been synthesized. These compounds were then subjected to substrate-controlled reactions such as Diels-Alder, epoxidation and Pauson-Khand reactions. The stereoselective outcome observed in these transformations is very promising for the future application of BiQuinazolinones as chiral auxiliaries.
| Item Type: | Article |
|---|---|
| Date Type: | Publication |
| Status: | Published |
| Schools: | Schools > Pharmacy |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RS Pharmacy and materia medica |
| Uncontrolled Keywords: | BiQuinazolinone; Atropisomers; Diastereoselectivity; Chiral induction |
| Publisher: | Elsevier |
| ISSN: | 0040-4020 |
| Date of First Compliant Deposit: | 23 January 2017 |
| Date of Acceptance: | 21 November 2016 |
| Last Modified: | 18 Nov 2024 05:15 |
| URI: | https://orca.cardiff.ac.uk/id/eprint/97657 |
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