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Number of items: 62.

Khanum, F., Bowen, Derrick John, Kerr, B. C. and Collins, P. W. 2014. Joint health scores in a haemophilia A cohort from Pakistan with minimal or no access to factor VIII concentrate: correlation with thrombin generation and underlying mutation. Haemophilia -Oxford- 20 (3) , pp. 426-434. 10.1111/hae.12326

Khanum, Fatima, Collins, Peter

, Harris, R.L. and Bowen, Derrick 2014. Characterization of F8 defects in haemophilia A in Pakistan: investigation of correlation between mutation type and the in vitro thrombin generation assay. Haemophilia 20 (2) , pp. 287-293. 10.1111/hae.12272

Burnett, Alan Kenneth, Hills, Robert Kerrin

, Hunter, A. E., Milligan, D., Kell, W. J., Wheatley, K., Yin, J., McMullin, M. F., Dignum, H., Bowen, Derrick John and Russell, Nicholas H. 2013. The addition of gemtuzumab ozogamicin to low-dose Ara-C improves remission rate but does not significantly prolong survival in older patients with acute myeloid leukaemia: results from the LRF AML14 and NCRI AML16 pick-a-winner comparison. Leukemia 27 , pp. 75-81. 10.1038/leu.2012.229

Palmer, Elizabeth, Gray, Lisa C., Stott, Matthew, Bowen, Derrick John and Van Den Berg, Carmen Wilma 2012. Roles of promoter and 3′ untranslated motifs in expression of the human C5a receptor. Molecular Immunology 52 (2) , pp. 88-95. 10.1016/j.molimm.2012.04.012

Davies, James Anthony

, Hathaway, Lee Sarah, Collins, Peter William

and Bowen, Derrick John 2012. von Willebrand factor: demographics of plasma protein level in a large blood donor cohort from South Wales in the United Kingdom [Letter]. Haemophilia 18 (3) , e79-e81. 10.1111/j.1365-2516.2012.02782.x

Harris, Rebecca, Van Den Berg, Carmen Wilma and Bowen, Derrick John 2012. ASGR1 and ASGR2, the genes that encode the asialoglycoprotein receptor (Ashwell receptor), are expressed in peripheral blood monocytes and show interindividual differences in transcript profile. Molecular Biology International 2012 10.1155/2012/283974

Bowen, Derrick John 2010. Sugar targets VWF for the chop (Comment on McGrath et al). Blood 115 (13) , p. 2565. 10.1182/blood-2009-12-256925

Sutherland, Megan S., Cumming, Anthony M., Bowman, Mackenzie, Bolton-Maggs, Paula H. B., Bowen, Derrick John, Collins, Peter William

, Hay, Charles R. M., Will, Andrew M. and Keeney, Stephen 2009. A novel deletion mutation is recurrent in von Willebrand disease types 1 and 3. Blood 114 (5) , pp. 1091-1098. 10.1182/blood-2008-08-173278

De Brasi, C. D. and Bowen, Derrick John 2008. Molecular characteristics of the intron 22 homologs of the coagulation factor VIII gene: an update [Letter]. Journal of Thrombosis and Haemostatis 6 (10) , pp. 1822-1824. 10.1111/j.1538-7836.2008.03094.x

Millar, Carolyn M., Riddell, Anne F., Brown, Simon A., Starke, Richard, Mackie, Ian, Bowen, Derrick John, Jenkins, P. Vincent and Van Mourik, Jan A. 2008. Survival of von Willebrand factor released following DDAVP in a type 1 von Willebrand disease cohort: influence of glycosylation, proteolysis and gene mutations. Thrombosis and Haemostasis 99 (5) , pp. 916-924. 10.1160/TH07-09-0565

Kingston, Jeanne, Bowen, Derrick John, Sweeney, Marion Carol

, Lawless, Susan, Jackson, Helen and Worwood, Mark 2007. Heteroduplex analysis for the three common HFE variants: methodology, reliablity and analysis of over 5000 requests for testing. Journal of Clinical Pathology 60 (11) , pp. 1244-1248. 10.1136/jcp.2006.042010

Green, P., Hill, M. and Bowen, Derrick John 2007. Duplications involving int22h-1 of the factor VIII gene: a cause for concern in genetic testing for hemophilia A? [Letter]. Journal of Thrombosis and Haemostasis 5 (10) , pp. 2155-2156. 10.1111/j.1538-7836.2007.02697.x

Bowen, Derrick John and Bowley, Steven 2007. Improved visualisation of high-molecular-weight von Willebrand factor multimers. Thrombosis and Haemostasis 97 (6) , pp. 1051-1052. 10.1160/TH06-12-0726

Davies, James Anthony

and Bowen, Derrick John 2007. The association between the L1565 variant of von Willebrand factor and susceptibility to proteolysis by ADAMTS13. Haematologica 92 (2) , pp. 240-243. 10.3324/haematol.10633

Davies, James Anthony

, Collins, Peter William

, Hathaway, Lee Sarah and Bowen, Derrick John 2007. von Willebrand factor: evidence for variable clearance in vivo according to Y/C1584 phenotype and ABO blood group. Journal of Thrombosis and Haemostatis 6 (1) , pp. 97-103. 10.1111/j.1538-7836.2007.02809.x

Davies, James Anthony

, Collins, Peter William

, Hathaway, Lee Sarah and Bowen, Derrick John 2006. The effect of von Willebrand factor Y/C1584 on in vivo protein level and function, and interaction with ABO blood group. Blood 109 (7) , pp. 2840-2846. 10.1182/blood-2006-07-035105

Cumming, Anthony, Grundy, Pamela, Keeney, Stephen, Lester, William, Enayat, Said, Guilliatt, Andrea, Bowen, Derrick John, Pasi, John, Keeling, David, Hill, Frank, Bolton-Maggs, Paula H. B., Hay, Charles and Collins, Peter William

2006. An investigation of the von Willebrand factor genotype in UK patients diagnosed to have type 1 von Willebrand disease. Journal of Thrombosis and Haemostasis 96 , pp. 630-641. 10.1160/TH06-07-0383

Bowen, Derrick John and Collins, Peter William

2006. Insights into von Willebrand factor proteolysis: clinical implications [Review]. British Journal of Haematology 133 (5) , pp. 457-467. 10.1111/j.1365-2141.2006.06096.x

Haj, M. A., Murch, N., Bowen, Derrick John, Sati, H. I., Beddal, A., Benton, A. and Collins, Peter William

2006. Cefotaxime as the potential cause of transient acquired von Willebrand syndrome. European Journal of Haematology 76 (5) , pp. 440-443. 10.1111/j.0902-4441.2006.t01-1-EJH2386.x

Bowen, Derrick John, Collins, Peter William

, Lester, Will, Cumming, Anthony M., Keeney, Steven, Grundy, Pamela, Enayat, Saad M., Bolton-Maggs, Paula H. B., Keeling, David M., Khair, Kate, Tait, R. Campbell, Wilde, Jonathon T., Pasi, K. John and Hill, Frank G. H. 2005. The prevalence of the cysteine1584 variant of von Willebrand factor is increased in type 1 von Willebrand disease: co-segregation with increased susceptibility to ADAMTS13 proteolysis but not clinical phenotype. British Journal of Haematology 128 (6) , pp. 830-836. 10.1111/j.1365-2141.2005.05375.x

Belli, Carolina, Bowen, Derrick John, De Brasi, Carlos and Larripa, Irene 2004. A single, multiplex analysis for all relevant activating NRAS gene mutations using heteroduplex generators. British Journal of Haematology 126 (4) , pp. 602-605. 10.1111/j.1365-2141.2004.05079.x

Bowen, Derrick John 2004. Increased susceptibility of von Willebrand factor to proteolysis by ADAMTS13: should the multimer profile be normal or type 2A? [Letter]. Blood -New York- 103 (8) , 3246. 10.1182/blood-2004-01-0376

Carter, Kymberley, Bowen, Derrick John, McCune, Catherine Anne and Worwood, Mark 2004. Response to Langlois et al (LE 01059). British Journal of Haematology 124 (4) , pp. 556-557. 10.1046/j.1365-2141.2003.04798.x

Bowen, Derrick John and Collins, Peter William

2004. An amino acid polymorphism in von Willebrand factor correlates with increased susceptibility to proteolysis by ADAMTS13. Blood 103 (3) , pp. 941-947. 10.1182/blood-2003-05-1505

Bowen, Derrick John 2003. Genome-wide linkage analysis of von Willebrand factor plasma levels implicates the ABO locus as a principal determinant: should we overlook ADAMTS13? Thrombosis and Haemostasis 90 (5) , p. 961.

Brown, Simon A., Eldridge, Adam, Collins, Peter William

and Bowen, Derrick John 2003. Increased clearance of von Willebrand factor antigen post-DDAVP in Type 1 von Willebrand disease: is it a potential pathogenic process? Journal Of Thrombosis And Haemostasis 1 (8) , pp. 1714-1717. 10.1046/j.1538-7836.2003.00359.x

Carter, Kymberley, Bowen, Derrick John, McCune, Catherine Anne and Worwood, Mark 2003. Haptoglobin type neither influences iron accumulation in normal subjects nor predicts clinical presentation in HFE C282Y haemochromatosis: phenotype and genotype analysis. British Journal of Haematology 122 (2) , pp. 326-332. 10.1046/j.1365-2141.2003.04436.x

Bowen, Derrick John 2003. An influence of ABO blood group on the rate of proteolysis of von Willebrand factor by ADAMTS13. Journal of Thrombosis and Haemostasis 1 (1) , pp. 33-40. 10.1046/j.1538-7836.2003.00007.x

Bowen, Derrick John and Keeney, Stephen 2003. Unleashing the long-distance PCR for detection of the intron 22 inversion of the factor VIII gene in severe haemophilia A [Letter]. Thrombosis and Haemostasis 89 (1) , pp. 201-202.

Bowen, Derrick John 2003. An influence of ABO blood group on the rate of proteolysis of von Willebrand factor by ADAMTS13. Journal of Thrombosis and Haemostatis 1 (1) , pp. 33-40. 10.1046/j.1538-7836.2003.00007.x

Rogers, Sarah A., Bowen, Derrick John, Ling, Min, Thomson, Peter, Wang, Zhiqing and Lim, Seah H. 2002. Identification and characterization of a novel gene encoding a SEREX antigen in chronic myeloid leukaemia. British Journal of Haematology 119 (1) , pp. 112-114. 10.1046/j.1365-2141.2002.03775.x

Brown, Simon A., Collins, Peter William

and Bowen, Derrick John 2002. Heterogeneous detection of A-antigen on von Willebrand factor derived from platelets, endothelial cells and plasma. Thrombosis and Haemostasis 87 (6) , pp. 990-996.

Brown, Simon A., Bowen, Derrick John, Hallett, Maurice Bartlett

, Giddings, John Charles and Collins, Peter William

2002. Factor VIIa induced release of von Willebrand factor from human umbilical vein endothelial cells by a tyrosine kinase dependent pathway. Journal of Thrombosis and Haemostasis 87 , pp. 1057-1061.

Bowen, Derrick John 2002. Haemophilia A and haemophilia B: molecular insights [Review. Corrected version]. Molecular Pathology 55 (2) , pp. 127-144. 10.1136/mp.55.2.127

Bowen, Derrick John 2002. Haemophilia A and haemophilia B: molecular insights [review]. Molecular Pathology 55 (1) , pp. 1-18. 10.1136/mp.55.1.1

De Brasi, C. D., Bowen, Derrick John, Collins, Peter William

and Larripa, I. B. 2002. The CpG island in intron 22 of the factor VIII gene is predominantly methylated on the X chromosome of human males. Journal of Human Genetics 47 (5) , pp. 239-242. 10.1007/s100380200032

De Brasi, C. D., Bowen, Derrick John, Collins, Peter William

and Larripa, I. B. 2002. The CpG island in intron 22 of the factor VIII gene is predominantly methylated on the X chromosome of human males. Journal of Human Genetics 47 (5) , pp. 239-242.

Bowen, Derrick John, MacLean, Rhona M., Pellard, Sarah and Collins, Peter William

2001. High concentrations of coagulation factor VIII and thrombosis: Is the factor VIII-binding domain of von Willebrand factor implicated? British Journal of Haematology 113 (3) , pp. 655-657. 10.1046/j.1365-2141.2001.02830.x

Bowen, Derrick John, De Brasi, C. D., Larripa, I. B. and Collins, Peter William

2000. A new polymorphism in the human factor VIII gene: implications for linkage analysis in haemophilia A and for the evolution of int22h sequences. British Journal of Haematology 111 (2) , pp. 544-548. 10.1111/j.1365-2141.2000.02373.x

Bowen, Derrick John 2000. An effective route for the isolation of human genetic loci exemplified using the BglI restriction fragment length polymorphism of the factor VIII gene. Thrombosis and Haemostasis 83 (3) , pp. 512-513.

De Brasi, C. D., Bowen, Derrick John, Collins, Peter William

and Larripa, I. B. 1999. Specific analysis of the intron 22 XbaI polymorphism of the human factor VIII gene using long-distance PCR. British Journal of Haematology 107 (3) , pp. 566-568. 10.1046/j.1365-2141.1999.01731.x

MacLean, R. M., Feeney, G. P., Bowley, S. J., Bowen, Derrick John, Worwood, Mark and Collins, Peter William

1999. Factor V Leiden and the common haemochromatosis mutation HFE C282Y: is there an association in familial venous thromboembolic disease? British Journal of Haematology 107 (1) , pp. 210-212. 10.1046/j.1365-2141.1999.01663.x

Howarth, A. and Bowen, Derrick John 1998. Linkage analysis in haemophilia A: simultaneous genotyping of two polymorphisms of the human factor VIII gene using induced heteroduplex formation. Haemophilia 4 (6) , pp. 812-819. 10.1046/j.1365-2516.1998.00202.x

Clark, Z. E., Bowen, Derrick John, Whatley, Sharon D., Bellamy, M. F., Collins, Peter William

and McDowell, Ian Frederick 1998. Genotyping method for methylenetetrahydrofolate reductase (C677T thermolabile variant) using heteroduplex technology [Technical Brief]. Clinical Chemistry 44 (11) , pp. 2360-2362.

Bowen, Derrick John, Standen, G. R., Mazurier, C., Gaucher, C., Cumming, A., Keeney, S. and Bidwell, J. 1998. Type 2N von Willebrand Disease: Rapid Genetic Diagnosis of G2811A (R854Q), C2696T (R816W), T2701A (H817Q) and G2823T (C858F) – Detection of a Novel Candidate Type 2N Mutation: C2810T (R854W). Thrombosis and Haemostasis 80 (1) , pp. 32-36.

Culpan, D., Goodeve, A., Bowen, Derrick John, Standen, G. and Bidwell, J. 1998. Rapid genotypic diagnosis of type 2A von Willebrand's disease by heteroduplex analysis. Clinical and Laboratory Haematology 20 (3) , pp. 177-178. 10.1046/j.1365-2257.1998.00111.x

Bowen, Derrick John, Bowley, S., John, M. and Collins, Peter William

1998. Factor V Leiden (G1691A), the Prothrombin 3’-Untranslated Region Variant (G20210A) and Thermolabile Methylenetetra-hydrofolate Reductase (C677T): A Single Genetic Test Genotypes all Three Loci – Determination of Frequencies in the S. Wales Population. Thrombosis and Haemostasis 79 (5) , pp. 949-954.

Jackson, H. A., Bowen, Derrick John and Worwood, Mark 1997. Rapid genetic screening for haemochromatosis using heteroduplex technology. British Journal of Haematology 98 (4) , pp. 856-859. 10.1046/j.1365-2141.1997.3193136.x

Bowen, Derrick John and Standen, G.R. 1997. Genetic detection of factor V Leiden: the question of specificity [Letter]. British Journal of Haematology 97 (3) , pp. 691-692.

Bowen, Derrick John, Standen, G. R., Granville, S., Bowley, S., Wood, N. A. and Bidwell, J. 1997. Genetic diagnosis of factor V Leiden using heteroduplex technology. Thrombosis and Haemostasis 77 (1) , pp. 119-122.

Aslam, S., Bowen, Derrick John, Mandalaki, T., Gialeraki, R. and Standen, G. R. 1996. Factor XIIIA subunit deficiency due to a homozygous 13-base pair deletion in exon 3 of the A subunit gene. American Journal of Hematology 53 (2) , pp. 77-80. 10.1002/(SICI)1096-8652(199610)53:2<77::AID-AJH4>3.0.CO;2-0

Bowen, Derrick John and Hampton, K. K. 1996. Analysis of the BglI restriction fragment length polymorphism in the human factor VIII gene using “virtual PCR”– a novel approach employing the polymerase chain reaction in the absence of sequence information for the locus. Human Genetics 98 (2) , pp. 219-222. 10.1007/s004390050195

Evans, Bronwen Alice James

, Bowen, Derrick John, Smith, P. J., Clayton, P. E. and Gregory, John Welbourn

1996. A new point mutation in the luteinising hormone receptor gene in familial and sporadic male limited precocious puberty: genotype does not always correlate with phenotype. Journal of Medical Genetics 33 (2) , pp. 143-147. 10.1136/jmg.33.2.143

Wood, Nicola Ruth, Standen, G. R., Bowen, Derrick John, Cumming, A., Lush, Christy, Lee, R. and Bidwell, J. 1996. UHG-based mutation screening in type 2B von Willebrand's disease: detection of a candidate mutation Ser547Phe. Thrombosis and Haemostasis 75 (2) , pp. 363-367.

Bowen, Derrick John, Raha-Chowdhury, R. and Worwood, Mark 1996. A new highly polymorphic marker in the 5' untranslated region of HLA-F shows strong allelic association with haemochromatosis. Human Genetics 97 (2) , pp. 228-231. 10.1007/BF02265271

Raha-Chowdhury, Ruma, Bowen, Derrick John, Stone, Caroline, Pointon, Jennifer J., Terwilliger, Joseph D., Shearman, Jeremy D., Robson, Kathryn J. H., Bomford, Adrian and Worwood, Mark 1995. New polymorphic microsatellite markers place the haemochromatosis gene telomeric to D6S105. Human Molecular Genetics 4 (10) , pp. 1869-1874. 10.1093/hmg/4.10.1869

Aslam, Shazia, Poon, Man-Chiu, Yee, Vivien C., Bowen, Derrick John and Standen, Graham R. 1995. Factor XIIIA calgary: a candidate missense mutation (Leu667Pro) in the beta barrel 2 domain of the factor XIIIA subunit. British Journal of Haematology 91 (2) , pp. 452-457. 10.1111/j.1365-2141.1995.tb05321.x

Raha-Chowdhury, R., Bowen, Derrick John, Burnett, Alan Kenneth and Worwood, Mark 1995. Allelic associations and homozygosity at loci from HLA-B to D6S299 in genetic haemochromatosis. Journal of Medical Genetics 32 (6) , pp. 446-452. 10.1136/jmg.32.6.446

Figueiredo, M. S., Bowen, Derrick John, Silva, W. A. and Zago, M. A. 1994. Factor IX gene haplotypes in Brazilian Blacks and characterization of unusual Ddel alleles. British Journal of Haematology 87 (4) , pp. 789-796. 10.1111/j.1365-2141.1994.tb06739.x

Worwood, Mark, Raha-Chowdhury, Ruma, Dorak, M. Tevfik, Darke, C., Bowen, Derrick John and Burnett, Alan Kenneth 1994. Alleles at D6S265 and D6S105 define a haemochromatosis-specific genotype. British Journal of Haematology 86 (4) , pp. 863-866. 10.1111/j.1365-2141.1994.tb04843.x

Standen, G. R. and Bowen, Derrick John 1993. Factor XIII ABristol 1: detection of a nonsense mutation (Arg171→+stop codon) in factor XIII A subunit deficiency. British Journal of Haematology 85 (4) , pp. 769-772. 10.1111/j.1365-2141.1993.tb03221.x

Bowen, Derrick John, Thomas, P., Webb, C. E., Bignell, P., Peake, I. R. and Bloom, A. L. 1991. Facile and rapid analysis of three DNA polymorphisms within the human factor IX gene using the polymerase chain reaction. British Journal of Haematology 77 (4) , pp. 559-560. 10.1111/j.1365-2141.1991.tb08626.x

This list was generated on Sat Jun 7 08:14:19 2025 BST.