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Number of items: 33.

Badder, Luned, Davies, James ORCID: https://orcid.org/0000-0003-3569-4500, Meniel, Valerie, Maruskova, Mahulena, Salvador, Beatriz, Bayliss, Rebecca ORCID: https://orcid.org/0000-0002-3324-957X, Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Hogan, Catherine ORCID: https://orcid.org/0000-0002-1012-0896 and Parker, Alan ORCID: https://orcid.org/0000-0002-9302-1761 2024. The αvβ6 integrin specific virotherapy, Ad5NULL-A20.FCU1, selectively delivers 2 potent “in-tumour” chemotherapy to Pancreatic Ductal Adenocarcinoma. British Journal of Cancer 131 , pp. 1694-1706. 10.1038/s41416-024-02869-3
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Bliss, Carly M., Hulin-Curtis, Sarah L., Williams, Marta, Marusková, Mahulena, Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Statkute, Evelina, Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Stack, Louise, Kerstetter, Lucas, Kerr-Jones, Lauren E., Milward, Kate, Russell, Gabrielle, George, Sarah J., Badder, Luned M., Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Coughlan, Lynda, Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2024. A pseudotyped adenovirus serotype 5 vector with serotype 49 fiber knob is an effective vector for vaccine and gene therapy applications. Molecular Therapy - Methods and Clinical Development 32 (3) , 101308. 10.1016/j.omtm.2024.101308
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Bates, Emily A., Lovatt, Charlotte, Plein, Alice R., Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2023. Engineering adenoviral vectors with improved GBM selectivity. Viruses 15 (5) , 1086. 10.3390/v15051086
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Bates, Emily A., Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Vánová, Jana, Nestic, Davor, Meniel, Valerie S., Koushyar, Sarah, Cunliffe, Tabitha G., Mundy, Rosie M., Moses, Elise, Uusi-Kerttula, Hanni K., Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Majhen, Dragomira, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Chester, John D. ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2022. Development of a low seroprevalence, αvβ6 integrin selective virotherapy based on human adenovirus type 10. Molecular Therapy - Oncolytics 25 , pp. 43-56. 10.1016/j.omto.2022.03.007
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Teijeira Crespo, Alicia, Burnell, Stephanie, Capitani, Lorenzo, Bayliss, Rebecca ORCID: https://orcid.org/0000-0002-3324-957X, Moses, Elise, Mason, Georgina H., Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Godkin, Andrew J. ORCID: https://orcid.org/0000-0002-1910-7567, Gallimore, Awen M. ORCID: https://orcid.org/0000-0001-6675-7004 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2021. Pouring petrol on the flames: using oncolytic virotherapies to enhance tumour immunogenicity. Immunology 163 (4) , pp. 389-398. 10.1111/imm.13323
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Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Marlow, Gareth ORCID: https://orcid.org/0000-0002-7608-9086, Uusi-Kerttula, Hanni K., Seaton, Gillian, Piggott, Luke, Badder, Luned M., Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Chester, John D. ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2021. Efficient intravenous tumor targeting using the αvβ6 integrin-selective precision virotherapy Ad5NULL-A20. Viruses 13 (5) , 864. 10.3390/v13050864
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Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Bates, Emily A., Moses, Elise, Mundy, Rosie M., Marlow, Gareth ORCID: https://orcid.org/0000-0002-7608-9086, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Bliss, Carly M., Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2021. The fiber knob protein of human adenovirus type 49 mediates highly efficient and promiscuous infection of cancer cell lines using a novel cell entry mechanism. Journal of Virology 95 (4) , e01849-20. 10.1128/JVI.01849-20
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Wongthida, Phonphimon, Schuelke, Matthew R., Driscoll, Christopher B., Kottke, Timothy, Thompson, Jill M, Tonne, Jason, Stone, Cathy, Huff, Amanda L., Wetmore, Cynthia, Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Evgin, Laura and Vile, Richard G. 2020. Ad-CD40L mobilizes CD4 T cells for the treatment of brainstem tumors. Neuro-Oncology 22 (12) , pp. 1757-1770. 10.1093/neuonc/noaa126
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Hulin-Curtis, Sarah ORCID: https://orcid.org/0000-0003-0889-964X, Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Nestic, Davor, Bates, Emily A., Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Cunliffe, Tabitha G., Majhen, Dragomira, Chester, John D. ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2020. Identification of folate receptor α (FRα) binding oligopeptides and their evaluation for targeted virotherapy applications. Cancer Gene Therapy 27 , pp. 785-798. 10.1038/s41417-019-0156-0
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Scurr, Martin J. ORCID: https://orcid.org/0000-0002-4120-0688, Greenshields-Watson, Alexander, Campbell, Emma, Somerville, Michelle, Chen, Yuan, Hulin-Curtis, Sarah L. ORCID: https://orcid.org/0000-0003-0889-964X, Burnell, Stephanie E. A., Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Davies, Michael M. ORCID: https://orcid.org/0000-0003-3569-4500, Hargest, Rachel ORCID: https://orcid.org/0000-0001-9830-3832, Phillips, Simon, Christian, Adam D., Ashelford, Kevin E. ORCID: https://orcid.org/0000-0003-3217-2811, Andrews, Robert, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2020. Cancer antigen discovery is enabled by RNA-sequencing of highly purified malignant and non-malignant cells. Clinical Cancer Research 10.1158/1078-0432.CCR-19-3087
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Elasifer, Hana, Wang, Eddie C.Y. ORCID: https://orcid.org/0000-0002-2243-4964, Prod'homme, Virginie ORCID: https://orcid.org/0000-0002-9664-4710, Davies, James ORCID: https://orcid.org/0000-0003-3569-4500, Forbes, Simone, Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Patel, Mihil, Fielding, Ceri A. ORCID: https://orcid.org/0000-0002-5817-3153, Roberts, Dawn, Traherne, James A., Gruber, Nicole, Bugert, Joachim J. ORCID: https://orcid.org/0000-0002-0556-3211, Aicheler, Rebecca J. and Wilkinson, Gavin W. G. 2020. Downregulation of HLA-I by the molluscum contagiosum virus mc080 impacts NK-cell recognition and promotes CD8+ T-cell evasion. Journal of General Virology 101 , pp. 863-872. 10.1099/jgv.0.001417
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Man, Stella, Foster, Julie, Carapuca, Elisabete, Davies, James A ORCID: https://orcid.org/0000-0003-3569-4500, Parker, Alan ORCID: https://orcid.org/0000-0002-9302-1761, Sosabowski, Jane and Hallden, Gunnel 2019. Systemic delivery and SPECT/CT in vivo imaging of 125I-labelled oncolytic adenoviral mutants in models of pancreatic cancer. Scientific Reports 9 , 12840. 10.1038/s41598-019-49150-9
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Baker, Alexander ORCID: https://orcid.org/0000-0001-8232-0531, Mundy, Rosie M., Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Rizkallah, Pierre and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2019. Human adenovirus type 26 uses sialic acid - bearing glycans as a primary cell entry receptor. Science Advances 5 (9) , eaax3567. 10.1126/sciadv.aax3567
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Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Mundy, Rosie, Davies, James ORCID: https://orcid.org/0000-0003-3569-4500, Rizkillah, Pierre T. and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2019. Adenovirus serotype 26 utilises sialic acid bearing glycans as a primary cell entry receptor. [Online]. bioRxiv. Available at: https://doi.org/10.1101/580076
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Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Greenshields-Watson, Alexander, Coughlan, Lynda, Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Uusi-Kerttula, Hanni, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2019. Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions. Nature Communications 10 , 741. 10.1038/s41467-019-08599-y
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Nobre, Luis V., Nightingale, Katie, Ravenhill, Benjamin J., Antrobus, Robin, Soday, Lior, Nichols, Jenna, Davies, James ORCID: https://orcid.org/0000-0003-3569-4500, Seirafian, Sepehr, Wang, Eddie C.Y. ORCID: https://orcid.org/0000-0002-2243-4964, Davison, Andrew J., Wilkinson, Gavin W.G., Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Huttlin, Edward L. and Weekes, Michael P. 2019. Human cytomegalovirus interactome analysis identifies degradation hubs, domain associations and viral protein functions. eLife 8 , e49894. 10.7554/eLife.49894
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Uusi-Kerttula, Hanni, Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Thompson, Jill M., Wongthida, Phonphimon, Evgin, Laura, Shim, Kevin G., Bradshaw, Angela, Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Jones, Rachel, Hanna, Louise, Hudson, Emma, Vile, Richard, Chester, John D. ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2018. Ad5NULL-A20 - a tropism-modified, αvβ6 integrin-selective oncolytic adenovirus for epithelial ovarian cancer therapies. Clinical Cancer Research 24 (17) , pp. 4215-4224. 10.1158/1078-0432.CCR-18-1089
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Hulin-Curtis, Sarah ORCID: https://orcid.org/0000-0003-0889-964X, Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Jones, Rachel, Hudson, Emma, Hanna, Louise, Chester, John D. ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2018. Histone deacetylase inhibitor trichostatin A sensitises cisplatin-resistant ovarian cancer cells to oncolytic adenovirus. Oncotarget 9 (41) , pp. 26328-26341. 10.18632/oncotarget.25242
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Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964, Pjechova, Marina, Nightingale, Katie, Vlachava, Virginia-Maria ORCID: https://orcid.org/0000-0003-4233-7739, Patel, Mihil, Ruckova, Eva, Forbes, Simone K., Nobre, Luis, Antrobus, Robin, Roberts, Dawn, Fielding, Ceri A. ORCID: https://orcid.org/0000-0002-5817-3153, Seirafian, Sepehr, Davies, James ORCID: https://orcid.org/0000-0003-3569-4500, Murrell, Isa, Lau, Betty, Wilkie, Gavin S., Suarez, Nicolas M., Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Vojtesek, Borivoj, Davison, Andrew, Lehner, Paul J., Weekes, Michael P., Wilkinson, Gavin W. G. ORCID: https://orcid.org/0000-0002-5623-0126 and Tomasec, Peter 2018. Suppression of costimulation by human cytomegalovirus promotes evasion of cellular immune defenses. Proceedings of the National Academy of Sciences 115 (19) , pp. 4998-5003. 10.1073/pnas.1720950115
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Man, Y. K. Stella, Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Coughlan, Lynda, Pantelidou, Constantia, Blázquez-Moreno, Alfonso, Marshall, John F., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 and Halldén, Gunnel 2018. The novel oncolytic adenoviral mutant Ad5-3Δ-A20T retargeted to αvβ6 integrins efficiently eliminates pancreatic cancer cells. Molecular Cancer Therapeutics 17 (2) , pp. 575-587. 10.1158/1535-7163.MCT-17-0671
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Uusi-Kerttula, Hanni, Davies, James ORCID: https://orcid.org/0000-0003-3569-4500, Curtis, Sarah ORCID: https://orcid.org/0000-0003-0889-964X, Chester, John ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan ORCID: https://orcid.org/0000-0002-9302-1761 2016. Pseudotyped αvβ6 integrin-targeted adenovirus vectors for ovarian cancer therapies. Oncotarget 7 (19) , pp. 27926-27937. 10.18632/oncotarget.8545
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Uusi-Kerttula, Hanni, Hulin-Curtis, Sarah ORCID: https://orcid.org/0000-0003-0889-964X, Davies, James Anthony ORCID: https://orcid.org/0000-0003-3569-4500 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2015. Oncolytic adenovirus: strategies and insights for vector design and immuno-oncolytic applications. Viruses 7 (11) , pp. 6009-6042. 10.3390/v7112923
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Uusi-Kerttula, Hanni, Legut, Mateusz, Davies, James Anthony ORCID: https://orcid.org/0000-0003-3569-4500, Jones, Rachel, Hudson, Emma, Hanna, Louise, Stanton, Richard James ORCID: https://orcid.org/0000-0002-6799-1182, Chester, John D. ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2015. Incorporation of peptides targeting EGFR and FGFR1 into the adenoviral fibre knob domain, and their evaluation as targeted cancer therapies. Human Gene Therapy 26 (5) , pp. 320-329. 10.1089/hum.2015.015
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Seirafian, Sepher, Prod'homme, Virginie ORCID: https://orcid.org/0000-0002-9664-4710, Sugrue, Daniel, Davies, James ORCID: https://orcid.org/0000-0003-3569-4500, Fielding, Ceri ORCID: https://orcid.org/0000-0002-5817-3153, Tomasec, Peter and Wilkinson, Gavin W. G. ORCID: https://orcid.org/0000-0002-5623-0126 2014. Human cytomegalovirus suppresses Fas expression and function. Journal of General Virology 95 (4) , pp. 933-939. 10.1099/vir.0.058313-0
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Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Seirafian, Sepher, Davies, James Anthony ORCID: https://orcid.org/0000-0003-3569-4500, Cuff, Simone ORCID: https://orcid.org/0000-0002-0546-3579, Aicheler, Rebecca, Sugrue, Daniel M., Davison, A., Stanton, Richard James ORCID: https://orcid.org/0000-0002-6799-1182, Wilkinson, Gavin William Grahame ORCID: https://orcid.org/0000-0002-5623-0126 and Tomasec, Peter 2012. A novel human cytomegalovirus gene function targets the natural killer cell activating ligand MICA for lysosomal degradation [Abstract]. Immunology 137 (S1) , p. 154. 10.1111/imm.12001

Davies, James Anthony ORCID: https://orcid.org/0000-0003-3569-4500, Hathaway, Lee Sarah, Collins, Peter William ORCID: https://orcid.org/0000-0002-6410-1324 and Bowen, Derrick John 2012. von Willebrand factor: demographics of plasma protein level in a large blood donor cohort from South Wales in the United Kingdom [Letter]. Haemophilia 18 (3) , e79-e81. 10.1111/j.1365-2516.2012.02782.x

Raby, Anne-Catherine ORCID: https://orcid.org/0000-0002-5354-5835, Holst, Benjamin, Davies, James Anthony ORCID: https://orcid.org/0000-0003-3569-4500, Colmont, Chantal Sophie, Laumonnier, Yves, Coles, Barbara, Shah, Sanjoy, Hall, Judith Elizabeth ORCID: https://orcid.org/0000-0002-6770-7372, Topley, Nicholas, Köhl, Jörg, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Labeta, Mario Oscar ORCID: https://orcid.org/0000-0001-5750-6983 2011. TLR activation enhances C5a-induced pro-inflammatory responses by negatively modulating the second C5a receptor, C5L2. European Journal of Immunology 41 (9) , pp. 2741-2752. 10.1002/eji.201041350
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Stanton, Richard James ORCID: https://orcid.org/0000-0002-6799-1182, Baluchova, Katarina, Dargan, Derrick J., Cunningham, Charles, Sheehy, Orla, Seirafian, Sepher, McSharry, Brian P., Neale, Margaret Lynne, Davies, James Anthony ORCID: https://orcid.org/0000-0003-3569-4500, Tomasec, Peter, Davison, Andrew J. and Wilkinson, Gavin William Grahame ORCID: https://orcid.org/0000-0002-5623-0126 2010. Reconstruction of the complete human cytomegalovirus genome in a BAC reveals RL13 to be a potent inhibitor of replication. Journal of Clinical Investigation 120 (9) , pp. 3191-3208. 10.1172/JCI42955
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Prod'homme, Virginie ORCID: https://orcid.org/0000-0002-9664-4710, Sugrue, Daniel M., Stanton, Richard James ORCID: https://orcid.org/0000-0002-6799-1182, Nomoto, A., Davies, James Anthony ORCID: https://orcid.org/0000-0003-3569-4500, Rickards, Carole R., Cochrane, Daniel, Moore, Melanie, Wilkinson, Gavin William Grahame ORCID: https://orcid.org/0000-0002-5623-0126 and Tomasec, Peter 2010. Human cytomegalovirus UL141 promotes efficient downregulation of the natural killer cell activating ligand CD112. Journal of General Virology 91 (8) , pp. 2034-2039. 10.1099/vir.0.021931-0

Raby, Anne-Catherine ORCID: https://orcid.org/0000-0002-5354-5835, Le Bouder, Emmanuel, Colmont, Chantal Sophie, Davies, James Anthony ORCID: https://orcid.org/0000-0003-3569-4500, Richards, Peter, Coles, Barbara, George, Christopher H., Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Topley, Nicholas and Labeta, Mario Oscar ORCID: https://orcid.org/0000-0001-5750-6983 2009. Soluble TLR2 reduces inflammation without compromising bacterial clearance by disrupting TLR2 triggering. The Journal of Immunology 183 (1) , pp. 506-517. 10.4049/jimmunol.0802909

Davies, James Anthony ORCID: https://orcid.org/0000-0003-3569-4500 and Bowen, Derrick John 2007. The association between the L1565 variant of von Willebrand factor and susceptibility to proteolysis by ADAMTS13. Haematologica 92 (2) , pp. 240-243. 10.3324/haematol.10633

Davies, James Anthony ORCID: https://orcid.org/0000-0003-3569-4500, Collins, Peter William ORCID: https://orcid.org/0000-0002-6410-1324, Hathaway, Lee Sarah and Bowen, Derrick John 2007. von Willebrand factor: evidence for variable clearance in vivo according to Y/C1584 phenotype and ABO blood group. Journal of Thrombosis and Haemostatis 6 (1) , pp. 97-103. 10.1111/j.1538-7836.2007.02809.x

Davies, James Anthony ORCID: https://orcid.org/0000-0003-3569-4500, Collins, Peter William ORCID: https://orcid.org/0000-0002-6410-1324, Hathaway, Lee Sarah and Bowen, Derrick John 2006. The effect of von Willebrand factor Y/C1584 on in vivo protein level and function, and interaction with ABO blood group. Blood 109 (7) , pp. 2840-2846. 10.1182/blood-2006-07-035105

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