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Number of items: 16.

Hole, Paul Spencer, Zabkiewicz, Joanna ORCID: https://orcid.org/0000-0003-0951-3825, Munje, Chinmay, Newton, Zarabeth, Pearn, Lorna, White, Paul Charles ORCID: https://orcid.org/0000-0002-6562-4696, Marquez, Nuria, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Burnett, Alan Kenneth, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2013. Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling. Blood 122 (19) , pp. 3322-3330. 10.1182/blood-2013-04-491944

Morgan, Rhys G., Pearn, Lorna, Liddiard, Kate ORCID: https://orcid.org/0000-0002-0953-1997, Pumford, Sara Louise, Burnett, Alan Kenneth, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2013. γ-Catenin is overexpressed in acute myeloid leukemia and promotes the stabilization and nuclear localization of β-catenin. Leukemia 27 (2) , pp. 336-343. 10.1038/leu.2012.221
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Zabkiewicz, Joanna ORCID: https://orcid.org/0000-0003-0951-3825, Pearn, Lorna, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Morgan, Rhys G., Burnett, Alan Kenneth, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2010. PDK1 overexpression in acute myeloid leukemia; Clinical significance and potential as a therapeutic target [Abstract]. Blood 116 (21) , pp. 892-893.

Morgan, Rhys Gareth, Pearn, Lorna, Liddiard, Kate ORCID: https://orcid.org/0000-0002-0953-1997, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Burnett, Alan Kenneth, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2010. Distinct regulation of beta- and gamma-Catenin throughout hematopoietic development contrasts with their cooperative roles in acute myeloid leukemia [Abstract]. Blood 116 (21) , 1573.

Hole, Paul Spencer, Pearn, Lorna, Tonks, Amanda Jayne ORCID: https://orcid.org/0000-0002-6073-4976, James, Philip Eurig, Burnett, Alan Kenneth, Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2010. Ras-induced reactive oxygen species promote growth factor-independent proliferation in human CD34+ hematopoietic progenitor cells. Blood 115 (6) , pp. 1238-1246. 10.1182/blood-2009-06-222869

Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Pearn, Lorna, Musson, Megan, Gilkes, Amanda F., Mills, Kenneth Ian, Burnett, Alan Kenneth and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2007. Transcriptional dysregulation mediated by RUNX1-RUNX1T1 in normal human progenitor cells and in acute myeloid leukaemia. Leukemia 21 (12) , pp. 2495-2505. 10.1038/sj.leu.2404961

Pearn, Lorna, Fisher, Janet, Burnett, Alan Kenneth and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2007. The role of PKC and PDK1 in monocyte lineage specification by Ras. Blood 109 (10) , pp. 4461-9. 10.1182/blood-2006-09-047217

Omidvar, Nader, Pearn, Lorna, Burnett, Alan Kenneth and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2006. Ral is both necessary and sufficient for the inhibition of myeloid differentiation mediated by Ras. Molecular and cellular biology 26 (10) , pp. 3966-75. 10.1128/MCB.26.10.3966-3975.2006
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Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Pearn, Lorna, Mills, Kenneth Ian, Burnett, Alan Kenneth and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2006. The sensitivity of human cells expressing RUNX1-RUNX1T1 to chemotherapeutic agents. Leukemia 20 (10) , pp. 1883-5. 10.1038/sj.leu.2404364

Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Tonks, Amanda Jayne ORCID: https://orcid.org/0000-0002-6073-4976, Pearn, Lorna, Mohamad, Zulkhairi, Burnett, Alan Kenneth and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2005. Optimized retroviral transduction protocol which preserves the primitive subpopulation of human hematopoietic cells. Biotechnology Progress 21 (3) , pp. 953-958. 10.1021/bp0500314

Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Tonks, Amanda Jayne, Pearn, Lorna, Pearce, Laurence, Hoy, Terence George, Couzens, Stephen, Fisher, Janet, Burnett, Alan Kenneth and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2004. Expression of AML1-ETO in human myelomonocytic cells selectively inhibits granulocytic differentiation and promotes their self-renewal. Leukemia 18 (7) , pp. 1238-1245. 10.1038/sj.leu.2403396

Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Tonks, Amanda Jayne, Pearn, Lorna, Pearce, L., Hoy, T., Couzens, Stephen, Fisher, J., Burnett, Alan Kenneth and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2004. Expression of AML1-ETO in human myelomonocytic cells selectively inhibits granulocytic differentiation and promotes their self-renewal. Leukemia 18 (7) , pp. 1238-1245. 10.1038/sj.leu.2403396

Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Pearn, Lorna, Tonks, Amanda Jayne, Pearce, Laurence, Hoy, Terence George, Phillips, Sarah, Fisher, Janet, Downing, James R., Burnett, Alan Kenneth and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2003. The AML-1 fusion gene promotes extensive self-renewal of human primary erythroid cells. Blood 101 (2) , pp. 624-632. 10.1182/blood-2002-06-1732

Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Pearn, Lorna, Tonks, Amanda Jayne, Pearce, Laurence, Hoy, Terence George, Phillips, Sarah, Fisher, Janet, Downing, James R., Burnett, Alan Kenneth and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2003. The AML1-ETO fusion gene promotes extensive self-renewal of human primary erythroid cells. Blood 101 (2) , pp. 624-632. 10.1182/blood-2002-06-1732

Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724, Pearn, Lorna, Omidvar, Nader, Sweeney, Marion Carol ORCID: https://orcid.org/0000-0003-0713-0855, Fisher, Janet, Phillips, Sarah, Hoy, Terence George and Burnett, Alan Kenneth 2002. Protein kinase C mediates mutant N-Ras-induced developmental abnormalities in normal human erythroid cells. Blood 100 (12) , pp. 4185-92. 10.1182/blood-2002-05-1358

Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724, Pearn, Lorna and Burnett, Alan Kenneth 2000. Mutant RAS promotes amplification of primitive human erythroid cells. Blood 96 (11) , 92A-92A.

This list was generated on Fri Apr 18 08:42:54 2025 BST.


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