Belder, Nevin, Charyyeva, Sulgun, Abaci Oruc, Edibe Ece, Kawalya, Hakiimu, Sahar, Namood-e, Omidvar, Nader, Savas, Berna, Ensari, Arzu and Ozdag, Hilal
2025.
Transformative insights from transcriptome analysis of colorectal cancer patient tissues: identification of four key prognostic genes.
PeerJ – the Journal of Life & Environmental Sciences
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10.7717/peerj.19852
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Dolton, Garry, Thomas, Hannah, Tan, Li Rong, Rius Rafael, Cristina ORCID: https://orcid.org/0000-0002-1896-1649, Doetsch, Stephanie, Ionescu, Giulia-Andreea, Cardo, Lucia F., Crowther, Michael D., Behiry, Enas, Morin, Théo, Caillaud, Marine E., Srai, Devinder, Parolini, Lucia, Hasan, Md Samiul, Fuller, Anna, Topley, Katie, Wall, Aaron, Hopkins, Jade R., Omidvar, Nader, Alvares, Caroline ORCID: https://orcid.org/0000-0003-4391-9802, Zabkiewicz, Joanna ORCID: https://orcid.org/0000-0003-0951-3825, Frater, John, Szomolay, Barbara ORCID: https://orcid.org/0000-0002-5375-5533 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135
2025.
MHC-related protein 1-restricted recognition of cancer via a semi-invariant TCR-α chain.
The Journal of Clinical Investigation
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Dolton, Garry, Bulek, Anna, Wall, Aaron, Thomas, Hannah, Hopkins, Jade R, Rius, Cristina, Galloway, Sarah A.E., Whalley, Thomas, Tan, Li Rong, Morin, Theo, Omidvar, Nader, Fuller, Anna, Topley, Katie, Hasan, Samiul, Jain, Shika, D’Souza, Nirupa, Hodges-Hoyland, Tom, Spiller, Owen B. ORCID: https://orcid.org/0000-0002-9117-6911, Kronenberg-Versteeg, Deborah, Szomolay, Barbara ORCID: https://orcid.org/0000-0002-5375-5533, van den Berg, Hugo A., Jones, Lucy C. ORCID: https://orcid.org/0000-0002-3872-4376, Peakman, Mark, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135
2024.
HLA A*24:02-restricted T-cell receptors cross recognise bacterial and preproinsulin peptides in type 1 diabetes.
Journal of Clinical Investigation
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10.1172/JCI164535
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Hajeyah, Ali A., Protty, Majd B., Paul, Divyani, Costa, Daniela ORCID: https://orcid.org/0000-0001-8821-5898, Omidvar, Nader, Morgan, Bethan, Iwasaki, Yugo, McGill, Beth, Jenkins, P. Vincent, Yousef, Zaheer, Allen-Redpath, Keith, Soyama, Shin, Choudhury, Anirban, Mitra, Rito, Yaqoob, Parveen, Morrissey, James H., Collins, Peter W. ORCID: https://orcid.org/0000-0002-6410-1324 and O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460
2024.
Phosphatidylthreonine is a procoagulant lipid detected in human blood and elevated in coronary artery disease.
Journal of Lipid Research
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10.1016/j.jlr.2023.100484
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Gorombei, Petra, Guidez, Fabien, Ganesan, Saravanan, Chiquet, Mathieu, Pellagatti, Andrea, Goursaud, Laure, Tekin, Nilgun, Beurlet, Stephanie, Patel, Satyananda, Guerenne, Laura, Le Pogam, Carole, Setterblad, Niclas, de la Grange, Pierre, LeBoeuf, Christophe, Janin, Anne, Noguera, Maria-Elena, Sarda-Mantel, Laure, Merlet, Pascale, Boultwood, Jacqueline, Konopleva, Marina, Andreeff, Michael, West, Robert, Pla, Marika, Adès, Lionel, Fenaux, Pierre, Krief, Patricia, Chomienne, Christine, Omidvar, Nader and Padua, Rose Ann
2021.
BCL-2 Inhibitor ABT-737 effectively targets leukemia-initiating cells with differential regulation of relevant genes leading to extended survival in a NRAS/BCL-2 mouse model of high risk-myelodysplastic syndrome.
International Journal of Molecular Sciences
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10.3390/ijms221910658
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Zabkiewicz, Joanna ORCID: https://orcid.org/0000-0003-0951-3825, Lazenby, Michelle, Edwards, Gareth, Bygrave, Ceri A., Omidvar, Nader, Zhuang, Lihui, Knapper, Steve ORCID: https://orcid.org/0000-0002-6405-4441, Guy, Carol, Hills, Robert K. ORCID: https://orcid.org/0000-0003-0166-0062, Burnett, Alan K. and Alvares, Caroline L. ORCID: https://orcid.org/0000-0003-4391-9802
2020.
Combination of a mitogen‐activated protein kinase inhibitor with the tyrosine kinase inhibitor pacritinib combats cell adhesion‐based residual disease and prevents re‐expansion of FLT3 ‐ITD acute myeloid leukaemia.
British Journal of Haematology
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10.1111/bjh.16665
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Robinson, Andrew J., Hopkins, Goitseone L., Rastogi, Namrata, Hodges, Marie, Doyle, Michelle, Davies, Sara, Hole, Paul S., Omidvar, Nader, Darley, Richard L. ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976
2020.
Reactive oxygen species drive proliferation in acute myeloid leukemia via the glycolytic regulator PFKFB3.
Cancer Research
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10.1158/0008-5472.CAN-19-1920
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| Carr, Robert, Ozdag, Hilal, Tekin, Nilgun, Morris, Timothy, Conget, Paulette, Bruna, Flavia, Timar, Botond, Gagyi, Eva, Basak, Ranjan, Naik, Omkar, Auewarakul, Chirayu, Srithana, Narongrit, Dimamay, Mark Pierre, Natividad, Filipinas, Chung, June-Key, Belder, Nevin, Kuzu, Isinsu, Omidvar, Nader, Paez, Diana and Padua, Rose Ann 2017. The effect of biological heterogeneity on R-CHOP treatment outcome in diffuse large B-cell lymphoma across five international regions. Leukemia and Lymphoma 58 (5) , pp. 1178-1183. 10.1080/10428194.2016.1231308 |
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Tekin, Nilgun, Omidvar, Nader, Morris, Tim Peter, Conget, Paulette, Bruna, Flavia, Timar, Botond, Gagyi, Eva, Basak, Ranjan, Naik, Omkar, Auewarakul, Chirayu, Sritana, Narongrit, Levy, Debora, Cerci, Juliano, Bydlowski, Sergio Paulo, Pereira, Juliana, Dimamay, Mark Pierre, Natividad, Filipinas, hung, June-Key, Belder, Nevin, Kuzu, Isinsu, Paez, Diana, Dondi, Maurizio, Carr, Robert, Ozdag, Hilal and Padua, Rose Ann
2016.
Protocol for qRT-PCR analysis from formalin fixed paraffin embedded tissue sections from diffuse large b-cell lymphoma: validation of the six-gene predictor score.
Oncotarget
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10.18632/oncotarget.13066
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| Keeshan, K., Vieugue, P., Chaudhury, S., Rishi, L., Gaillard, C., Liang, L., Garcia, E., Nakamura, T., Omidvar, Nader and Kogan, S. C. 2016. Co-operative leukemogenesis in acute myeloid leukemia and acute promyelocytic leukemia reveals C/EBP as a common target of TRIB1 and PML/RARA. Haematologica 101 (10) , pp. 1228-1036. 10.3324/haematol.2015.138503 |
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| Guerenne, Laura, Beurlet, Stéphanie, Said, Mohamed, Gorombei, Petra, Le Pogam, Carole, Guidez, Fabien, de la Grange, Pierre, Omidvar, Nader, Vanneaux, Valérie, Mills, Ken, Mufti, Ghulam J, Sarda-Mantel, Laure, Noguera, Maria Elena, Pla, Marika, Fenaux, Pierre, Padua, Rose Ann, Chomienne, Christine and Krief, Patricia 2016. GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathways. Journal of Hematology & Oncology 9 (5) , PMC4728810. 10.1186/s13045-016-0235-8 |
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| Pogam, Carole Le, Patell, Satyananda, Gorombei, Petra, Guerenne, Laura, Krief, Patricia, Omidvar, Nader, Tekin, Nilgun, Bernasconi, Elena, Sicre, Flore, Schlageter, Marie-Helene, Chopin, Martine, Noguera, Maria-Elena, West, Robert, Abu, Ansu, Mathews, Vikram, Pla, Marika, Fenaux, Pierre, Chomienne, Christine and Padua, Rose Ann 2015. DNA-mediated adjuvant immunotherapy extends survival in two different mouse models of myeloid malignancies. Oncotarget 6 (32) , pp. 32494-32508. 10.18632/oncotarget.5572 |
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Piggott, Luke, Omidvar, Nader, Martí Pérez, Salvador, French, Rhiannon, Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348 and Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673
2015.
Erratum to: Suppression of apoptosis inhibitor c-FLIP selectively eliminates breast cancer stem cell activity in response to the anti-cancer agent, TRAIL.
Breast Cancer Research
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10.1186/s13058-015-0597-9
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| Le Pogam, Carole, Krief, Patricia, Beurlet, Stephanie, Soulié, Annie, Balitrand, Nicole, Cassinat, Bruno, Cavé, Helene, Kosmider, Olivier, Setterblad, Niclas, Leboeuf, Christophe, Sarda-Mantel, Laure, Hervatin, Florence, Merlet, Pascal, Noguera, Maria-Elena, Janin, Anne, Pla, Marika, Fontenay, Michaela, Adès, Lionel, Fenaux, Pierre, Chomienne, Christine, Padua, Rose Ann and Omidvar, Nader 2013. Localization of the NRAS:BCL-2 complex determines anti-apoptotic features associated with progressive disease in myelodysplastic syndromes. Leukemia Research 37 (3) , pp. 312-319. 10.1016/j.leukres.2012.10.018 |
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| Omidvar, Nader, Maunakea, M. L., Jones, L., Sevcikova, S., Yin, B., Himmel, K. L., Tennant, T. R., Le Beau, M. M., Largaespada, D. A. and Kogan, S. C. 2013. PML-RAR co-operates with Sox4 in acute myeloid leukemia development in mice. Haematologica 98 (3) , pp. 424-427. 10.3324/haematol.2011.057067 |
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Piggott, Luke, Omidvar, Nader, Marti-Perez, Salvador, Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348 and Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673
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Suppression of apoptosis inhibitor c-FLIP selectively eliminates breast cancer stem cell activity in response to the anti-cancer agent, TRAIL.
Breast Cancer Research
13
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, R88.
10.1186/bcr2945
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Kreuzaler, Peter A., Staniszewska, Anna D., Li, Wenjing, Omidvar, Nader, Kedjouar, Blandine, Turkson, James, Poli, Valeria, Flavell, Richard A., Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 and Watson, Christine J.
2011.
Stat3 controls lysosomal-mediated cell death in vivo.
Nature Cell Biology
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10.1038/ncb2171
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Tiffen, P., Omidvar, Nader, Marquez, Nuria, Croston, D., Watson, C. and Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673
2008.
A dual role for Oncostatin M signalling in the differentiation and death of mammary epithelial cells in vivo.
Molecular Endocrinology
22
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10.1210/me.2008-0097
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| Rassool, Feyruz V., Gaymes, Terry J., Omidvar, Nader, Brady, Nichola, Beurlet, Stephanie, Pla, Marika, Reboul, Murielle, Lea, Nicholas, Chomienne, Christine, Thomas, Nicholas S. B., Mufti, Ghulam J. and Padua, Rose Anne 2007. Reactive Oxygen Species, DNA Damage, and Error-Prone Repair: A Model for Genomic Instability with Progression in Myeloid Leukemia? Cancer Research 67 (18) , pp. 8762-8771. 10.1158/0008-5472.CAN-06-4807 |
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| Omidvar, Nader, Kogan, S., Beurlet, S., le Pogam, C., Janin, A., West, Robert R., Noguera, M.-E., Reboul, M., Soulie, A., Leboeuf, C., Setterblad, N., Felsher, D., Lagasse, E., Mohamedali, A., Thomas, N. S. B., Fenaux, P., Fontenay, M., Pla, M., Mufti, G. J., Weissman, I., Chomienne, C. and Padua, R. A. 2007. BCL-2 and Mutant NRAS Interact Physically and Functionally in a Mouse Model of Progressive Myelodysplasia. Cancer Research 67 (24) , pp. 11657-11667. 10.1158/0008-5472.CAN-07-0196 |
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Omidvar, Nader, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Longhi, Maria P., Smith, Richard A. G. and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676
2006.
Expression of glycosylphosphatidylinositol-anchored CD59 on target cells enhances human NK cell-mediated cytotoxicity.
The Journal of Immunology
176
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, pp. 2915-2923.
10.4049/jimmunol.176.5.2915
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Omidvar, Nader, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Longhi, M. Paula, Smith, Richard A. G. and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676
2006.
Expression of glycosylphosphatidylinositol-anchored CD59 on target cells enhances human NK cell-mediated cytotoxicity.
Journal of immunology
176
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, pp. 2915-2923.
|
|
Omidvar, Nader, Pearn, Lorna, Burnett, Alan Kenneth and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724
2006.
Ral is both necessary and sufficient for the inhibition of myeloid differentiation mediated by Ras.
Molecular and cellular biology
26
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, pp. 3966-75.
10.1128/MCB.26.10.3966-3975.2006
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Longhi, M. Paula, Baalasubramanian, Sivasankar, Omidvar, Nader, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004
2005.
Cutting edge: murine CD59a modulates antiviral CD4+ T cell activity in a complement-independent manner.
Journal of Immunology
175
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, pp. 7098-7102.
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Baalasubramanian, Sivasankar, Harris, Claire Louise, Donev, Rossen Mintchev, Mizuno, Masashi, Omidvar, Nader, Song, Wen-Chao and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676
2004.
CD59a is the primary regulator of membrane attack complex assembly in the mouse.
Journal of Immunology
173
, pp. 3684-3692.
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Sivasankar, B., Mizuno, Masashi, Donev, Rossen Mintchev, Omidvar, Nader, Harris, Claire Louise, Song, W. C. and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676
2004.
CD59b is expressed at low level on mouse erythrocytes and has a negligible protective role in the presence of CD59a.
Molecular Immunology
41
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, pp. 307-308.
10.1016/j.molimm.2004.03.002
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Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724, Pearn, Lorna, Omidvar, Nader, Sweeney, Marion Carol ORCID: https://orcid.org/0000-0003-0713-0855, Fisher, Janet, Phillips, Sarah, Hoy, Terence George and Burnett, Alan Kenneth
2002.
Protein kinase C mediates mutant N-Ras-induced developmental abnormalities in normal human erythroid cells.
Blood
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10.1182/blood-2002-05-1358
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