Kourti, Malamati, Westwell, Andrew ORCID: https://orcid.org/0000-0002-5166-9236, Jiang, Wen ORCID: https://orcid.org/0000-0002-3283-1111 and Cai, Jun 2019. Repurposing old carbon monoxide-releasing molecules towards the anti-angiogenic therapy of triple-negative breast cancer. Oncotarget 10 (10) , pp. 1132-1148. 10.18632/oncotarget.26638 |
Yang, W, Cai, Jun, Zhang, Huiming, Wang, Guyan and Jiang, W ORCID: https://orcid.org/0000-0002-3283-1111 2018. Effects of lidocaine and ropivacaine on gastric cancer cells through down-regulation of ERK1/2 phosphorylation in vitro. Anticancer Research 38 (12) , pp. 6729-6735. 10.21873/anticanres.13042 |
Harries, Rhiannon L., Owen, Sioned, Ruge, Fiona, Morgan, Meleri, Li, Jun, Zhang, Zhangtao, Harding, Keith G., Torkington, Jared, Jiang, Wen G. ORCID: https://orcid.org/0000-0002-3283-1111 and Cai, Jun 2018. Impact of pigment epithelium-derived factor on colorectal cancer in vitro and in vivo. Oncotarget 9 (27) , pp. 19192-19202. 10.18632/oncotarget.24953 |
Cai, Shuo, Cai, Jun, Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 and Ye, Lin ORCID: https://orcid.org/0000-0002-0303-2409 2017. Kidins220 and tumour development: Insights into a complexity of cross-talk among signalling pathways (Review). International Journal of Molecular Medicine 40 (4) , pp. 965-971. 10.3892/ijmm.2017.3093 |
Lopes-Bastos, Bruno, Jin, Liang, Ruge, Fiona, Owen, Sioned, Sanders, Andrew J. ORCID: https://orcid.org/0000-0002-7997-5286, Cogle, Christopher, Chester, John D. ORCID: https://orcid.org/0000-0002-7830-3840, Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 and Cai, Jun 2017. Association of breast carcinoma growth with a non-canonical axis of IFNγ/IDO1/TSP1. Oncotarget 10.18632/oncotarget.18781 |
Yang, Wenjing, Cai, Jun, Zabkiewicz, Catherine, Zhang, Huimin, Ruge, Fiona and Jiang, Wen ORCID: https://orcid.org/0000-0002-3283-1111 2017. The effects of anesthetics on recurrence and metastasis of cancer, and clinical implications. World Journal of Oncology 8 (3) , pp. 63-70. 10.14740/wjon1031e |
Kourti, Malamati, Jiang, Wen ORCID: https://orcid.org/0000-0002-3283-1111 and Cai, Jun 2017. Aspects of carbon monoxide in form of CO-releasing molecules used in cancer treatment: More light on the way. Oxidative Medicine and Cellular Longevity 2017 , 9326454. 10.1155/2017/9326454 |
Cai, Jun 2016. Editorial foreword special issue: "Angiogenesis-convergent or divergent, that is the question: Research toward targeted strategies in oncology". Cancer Letters 380 (2) , pp. 523-524. 10.1016/j.canlet.2016.03.039 |
Jia, S. and Cai, Jun 2016. Update on biomarkers in development of anti-angiogenic drugs in gastric cancer. Anticancer Research 36 (3) , pp. 1111-1118. |
Lopes-Bastos, Bruno Miguel, Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 and Cai, Jun 2016. Tumour-endothelial cell communications: important and indispensable mediators of tumour angiogenesis. Anticancer Research 36 (3) , pp. 1119-1126. |
Gao, Xiang, Li, Lin, Wang, Xiao, Wen, Xian, Ji, Ke, Ye, Lin ORCID: https://orcid.org/0000-0002-0303-2409, Cai, Jun, Jiang, Wen ORCID: https://orcid.org/0000-0002-3283-1111 and Ji, Jia 2015. Inhibition of sphingosine-1-phosphate phosphatase 1 promotes cancer cells migration in gastric cancer: clinical implications. Oncology Reports 34 (4) , pp. 1977-1987. 10.3892/or.2015.4162 |
Harries, Rhian, Cai, Jun, Li, J., Owen, S., Harding, Keith Gordon, Torkington, Jared and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2015. PTH-329 Expression of pigment epithelium-derived factor in colorectal cancer [Abstract]. Gut 64 (S1) , A554. 10.1136/gutjnl-2015-309861.1215 |
Chen, Zhijuan, Ruan, Qing, Han, Song, Xi, Lei, Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Jiang, Huabei, Ostrov, David A. and Cai, Jun 2014. Discovery of structure-based small molecular inhibitor of alpha B-crystallin against basal-like/triple-negative breast cancer development in vitro and in vivo. Breast Cancer Research and Treatment 145 (1) , pp. 45-59. 10.1007/s10549-014-2940-8 |
Ruan, Qing, Xi, Lei, Boye, Sanford L., Han, Song, Chen, Zhi J., Hauswirth, William W., Lewin, Alfed S., Boulton, Michael E., Law, Brian K., Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Jiang, Huabei and Cai, Jun 2013. Development of an anti-angiogenic therapeutic model combining scAAV2-delivered siRNAs and noninvasive photoacoustic imaging of tumor vasculature development. Cancer Letters 332 (1) , pp. 120-129. 10.1016/j.canlet.2012.11.016 |
Liu, Li, Qi, Xiaoping, Chen, Zhijuan, Shaw, Lynn, Cai, Jun, Smith, Layton H., Grant, Maria B. and Boulton, Michael E. 2013. Targeting the IRE1α/XBP1 and ATF6 arms of the unfolded protein response enhances VEGF blockade to prevent retinal and choroidal neovascularization. American Journal of Pathology 182 (4) , pp. 1412-1424. 10.1016/j.ajpath.2012.12.020 |
Cai, Jun, Ruan, Qing, Chen, Zhi J. and Han, Song 2012. Connection of pericyte–angiopoietin-Tie-2 system in diabetic retinopathy: friend or foe? Future Medicinal Chemistry 4 (17) , pp. 2163-2176. 10.4155/fmc.12.170 |
Cai, Jun, Qi, Xiaoping, Kociok, Norbert, Skosyrski, Sergej, Emilio, Alonso, Ruan, Qing, Han, Song, Liu, Li, Chen, Zhijuan, Bowes Rickman, Catherine, Golde, Todd, Grant, Maria B., Saftig, Paul, Serneels, Lutgarde, de Strooper, Bart, Joussen, Antonia M. and Boulton, Michael Edwin 2012. ?-Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment. EMBO Molecular Medicine 4 (9) , pp. 980-991. 10.1002/emmm.201101084 |
Qi, Xiaoping, Cai, Jun, Ruan, Qing, Liu, Li, Boye, Sanford L., Chen, Zhijuan, Hauswirth, William W., Ryals, Renee C., Shaw, Lynn, Caballero, Sergio, Grant, Maria B. and Boulton, Michael Edwin 2012. y-secretase inhibition of murine choroidal neovascularization is associated with reduction of superoxide and proinflammatory cytokines. Investigative Ophthalmology & Visual Science 53 (2) , pp. 574-585. 10.1167/iovs.11-8728 |
Tjwa, Marc, Jarajapu, Yagna P. R., Cai, Jun, Yan, Yuanqing, Li Calzi, Sergio, Kielczewski, Jennifer L., Hu, Ping, Shaw, Lynn C., Firth, Sue M., Chan-Ling, Tailoi, Boulton, Michael, Baxter, Robert C. and Grant, Maria B. 2012. Protection of blood retinal barrier and systemic vasculature by insulin-like growth factor binding protein-3. PLoS ONE 7 (7) , e39398. 10.1371/journal.pone.0039398 |
Gonzalez, Pedro, Thampi, Prajitha, Rao, Haripriya Vittal, Mitter, Sayak K., Cai, Jun, Mao, Haoyu, Li, Hong, Seo, Soojung, Qi, Xiaoping, Lewin, Alfred S., Romano, Carl and Boulton, Michael 2012. The 5HT1a receptor agonist 8-Oh DPAT induces protection from lipofuscin accumulation and oxidative stress in the retinal pigment epithelium. PLoS ONE 7 (4) , e34468. 10.1371/journal.pone.0034468 |
Mitter, Sayak K., Rao, Haripriya Vittal, Qi, Xiaoping, Cai, Jun, Sugrue, Andrew, Dunn, William A., Grant, Maria B. and Boulton, Michael 2012. Autophagy in the retina: a potential role in age-related macular degeneration. Advances in Experimental Medicine and Biology 723 , pp. 83-90. 10.1007/978-1-4614-0631-0_12 |
Kielczewski, Jennifer L., Calzi, Sergio Li, Shaw, Lynn C., Cai, Jun, Qi, Xiaoping, Ruan, Qing, Wu, Lin, Liu, Li, Hu, Ping, Chan-Ling, Tailoi, Mames, Robert N., Firth, Sue, Baxter, Robert C., Turowski, Patric, Busik, Julia V., Boulton, Michael and Grant, Maria B. 2011. Free insulin-like growth factor binding protein-3 (IGFBP-3) reduces retinal vascular permeability in association with a reduction of acid sphingomyelinase (ASMase). Investigative Ophthalmology & Visual Science 52 (11) , pp. 8278-8286. 10.1167/iovs.11-8167 |
Gaetano, Carlo, Cai, Jun, Wu, Lin, Qi, Xiaoping, Li Calzi, Sergio, Caballero, Sergio, Shaw, Lynn, Ruan, Qing, Grant, Maria B. and Boulton, Michael E. 2011. PEDF regulates vascular permeability by a γ-secretase-mediated pathway. PLoS ONE 6 (6) , e21164. 10.1371/journal.pone.0021164 |
Cai, Jun 2011. In pursuit of new anti-angiogenic therapies for cancer treatment. Frontiers in Bioscience 16 (1) , pp. 803-814. 10.2741/3721 |
Ruan, Q., Han, S., Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Boulton, M. E., Chen, Z. J., Law, B. K. and Cai, Jun 2011. B-Crystallin, an effector of unfolded protein response, confers anti-VEGF resistance to breast cancer via maintenance of intracrine VEGF in endothelial cells [RETRACTED]. Molecular Cancer Research 9 (12) , pp. 1632-1643. 10.1158/1541-7786.MCR-11-0327 |
Cai, Jun, Chen, Z., Ruan, Q., Han, S., Liu, L., Qi, X., Boye, S. L., Hauswirth, W. W., Grant, M. B. and Boulton, Michael Edwin 2011. γ-secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1. Journal of Biological Chemistry 286 (49) , pp. 42514-42523. 10.1074/jbc.M111.296590 |
Kielczewski, J. L., Jarajapu, Y. P. R., McFarland, E. L., Cai, Jun, Afzal, A., Li Calzi, S., Chang, K. H., Lydic, T., Shaw, L. C., Busik, J., Hughes, J., Cardounel, A. J., Wilson, K., Lyons, T. J., Boulton, Michael, Mames, R. N., Chan-Ling, T. and Grant, M. B. 2009. Insulin-like growth factor binding protein-3 mediates vascular repair by enhancing nitric oxide generation. Circulation Research 105 (9) , pp. 897-905. 10.1161/CIRCRESAHA.109.199059 |
Boulton, Michael, Cai, Jun and Grant, Maria B. 2008. γ-Secretase: a multifaceted regulator of angiogenesis. Journal of Cellular and Molecular Medicine 12 (3) , pp. 781-795. 10.1111/j.1582-4934.2008.00274.x |
Cai, Jun, Kehoe, Oksana, Smith, Gill M., Hykin, Philip and Boulton, Michael E. 2008. The angiopoietin/Tie-2 system regulates pericyte survival and recruitment in diabetic retinopathy. Investigative Ophthalmology & Visual Science 49 (5) , pp. 2163-2171. 10.1167/iovs.07-1206 |
Boulton, Michael, Cai, Jun, Grant, Maria B. and Zhang, Yadan 2008. Gamma-secretase regulates VEGFR-1 signalling in vascular endothelium and RPE. Advances in Experimental Medicine and Biology 613 , pp. 313-319. 10.1007/978-0-387-74904-4_36 |
Zhao, B., Ma, A., Cai, Jun and Boulton, Michael 2006. VEGF-A regulates the expression of VEGF-C in human retinal pigment epithelial cells. British Journal of Ophthalmology 90 (8) , pp. 1052-1059. 10.1136/bjo.2006.091215 |
Cai, Jun, Jiang, Wen G., Ahmed, Asif and Boulton, Michael Edwin 2006. Vascular endothelial growth factor-induced endothelial cell proliferation is regulated by interaction between VEGFR-2, SH-PTP1 and eNOS. Microvascular Research 71 (1) , pp. 20-31. 10.1016/j.mvr.2005.10.004 |
Zhao, B., Smith, G., Cai, Jun, Ma, A. and Boulton, M. 2006. Vascular endothelial growth factor C promotes survival of retinal vascular endothelial cells via vascular endothelial growth factor receptor-2. British Journal of Ophthalmology 91 (4) , pp. 538-545. 10.1136/bjo.2006.101543 |
Zhao, B., Cai, Jun and Boulton, Michael 2004. Expression of placenta growth factor is regulated by both VEGF and hyperglycaemia via VEGFR-2. Microvascular Research 68 (3) , pp. 239-246. 10.1016/j.mvr.2004.07.004 |
Cai, Jun and Boulton, M. 2002. The pathogenesis of diabetic retinopathy: old concepts and new questions. Eye 16 (3) , pp. 242-260. 10.1038/sj.eye.6700133 |
Cai, Jun, Jiang, Wen ORCID: https://orcid.org/0000-0002-3283-1111 and Mansel, Robert ORCID: https://orcid.org/0000-0002-8051-0726 1999. Phosphorylation and disorganization of vascular-endothelial cadherin in interaction between breast cancer and vascular endothelial cells. International Journal of Molecular Medicine 4 (2) , pp. 191-195. 10.3892/ijmm.4.2.191 |
Cai, Jun, Jiang, Wen ORCID: https://orcid.org/0000-0002-3283-1111 and Mansel, Robert ORCID: https://orcid.org/0000-0002-8051-0726 1999. Inhibition of the expression of VE-cadherin/catenin complex by gamma linolenic acid in human vascular endothelial cells, and its impact on angiogenesis. Biochemical and Biophysical Research Communications 258 (1) , pp. 113-118. 10.1006/bbrc.1999.0596 |
Cai, Jun, Jiang, Wen ORCID: https://orcid.org/0000-0002-3283-1111 and Mansel, Robert ORCID: https://orcid.org/0000-0002-8051-0726 1999. Inhibition of angiogenic factor- and tumour-induced angiogenesis by gamma linolenic acid. Prostaglandins Leukotrienes & Essential Fatty Acids 60 (1) , pp. 21-29. 10.1054/plef.1998.0004 |
Cai, Jun, Jiang, Wen ORCID: https://orcid.org/0000-0002-3283-1111 and Mansel, Robert ORCID: https://orcid.org/0000-0002-8051-0726 1998. Gap junctional communication and the tyrosine phosphorylation of connexin 43 in interaction between breast cancer and endothelial cells. International Journal of Molecular Medicine 1 (1) , pp. 273-278. 10.3892/ijmm.1.1.273 |