Yang, Bin, Borgeaud, Alicia C., Buřičová, Marcela, Aeschbach, Lorène, Rodríguez-Lima, Oscar, Ruiz Buendía, Gustavo A., Cinesi, Cinzia, Taylor, Alysha S., Baubec, Tuncay and Dion, Vincent
2022.
Expanded CAGCTG repeats resist gene silencing mediated by targeted epigenome editing.
Human Molecular Genetics
31
(3)
, pp. 386-398.
10.1093/hmg/ddab255
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Wheeler, Vanessa and Dion, Vincent
2021.
Modifiers of CAG repeat instability: insights from mammalian models.
Journal of Huntington's Disease
10
(1)
, pp. 123-148.
10.3233/JHD-200426
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Ruiz Buendía, Gustavo A., Leleu, Marion, Marzetta, Flavia, Vanzan, Ludovica, Tan, Jennifer, Ythier, Victor, Randall, Emma L., Marques, Ana C., Baubec, Tuncay, Murr, Rabih, Xenarios, Ioannis and Dion, Vincent
2020.
Three-dimensional chromatin interactions remain stable upon CAG/CTG repeat expansion.
Science Advances
6
(27)
, eaaz4012.
10.1126/sciadv.aaz4012
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Cinesi, Cinzia, Yang, Bin and Dion, Vincent 2019. GFP reporters to monitor instability and expression of expanded CAG/CTG repeats. In: Richard, Guy-Franck ed. Trinucleotide Repeats: Methods and Protocols, Vol. 2056. Methods in Molecular Biology, Humana Press, pp. 255-268. (10.1007/978-1-4939-9784-8_16) |
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Malbec, Rémi, Chami, Bayan, Aeschbach, Lorène, Ruiz Buendía, Gustavo A., Socol, Marius, Joseph, Pierre, Leïchlé, Thierry, Trofimenko, Evgeniya, Bancaud, Aurélien and Dion, Vincent
2019.
µLAS: Sizing of expanded trinucleotide repeats with femtomolar sensitivity in less than 5 minutes.
Scientific Reports
9
(1)
, 23.
10.1038/s41598-018-36632-5
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Yang, Bin, Borgeaud, Alicia, Aeschbach, Lorene and Dion, Vincent
2018.
Uncovering the interplay between epigenome editing efficiency and sequence context using a novel inducible targeting system.
[Online].
bioRxiv.
Available at: https://doi.org/10.1101/368480
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Malbec, R., Chami, B., Ngo, H. H. T., Didelot, A., Garlan, F., Garrigou, S., Taly, V., Aeschbach, Lorene, Trofimenko, Evgeniya, Dion, Vincent, Boutonnet-Rodat, A., Ginot, F. and Bancaud, A. 2018. Direct characterization of circulating DNA in blood plasma using μLAS technology. Presented at: IEEE International Electron Devices Meeting (IEDM 2017), San Francisco, CA, USA, 2-6 December 2017. 2017 IEEE International Electron Devices Meeting (IEDM). IEEE, 26.5.1-26.5.4. 10.1109/IEDM.2017.8268465 |
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Dion, Vincent and Aeschbach, Lorène
2017.
Minimizing carry-over PCR contamination in expanded CAG/CTG repeat instability applications.
Scientific Reports
7
, 18026.
10.1038/s41598-017-18168-2
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Cinesi, Cinzia, Aeschbach, Lorène, Yang, Bin and Dion, Vincent
2016.
Contracting CAG/CTG repeats using the CRISPR-Cas9 nickase.
Nature Communications
7
, 13272.
10.1038/ncomms13272
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Su, Xiaofeng A., Dion, Vincent, Gasser, Susan M. and Freudenreich, Catherine H. 2015. Regulation of recombination at yeast nuclear pores controls repair and triplet repeat stability. Genes {&} Development 29 (10) , 1006--1017. 10.1101/gad.256404.114 |
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Horigome, Chihiro, Dion, Vincent, Seeber, Andrew, Gehlen, Lutz R. and Gasser, Susan M. 2015. Visualizing the Spatiotemporal Dynamics of DNA Damage in Budding Yeast. Stress reponses, Methods in Molecular Biology, New York: Springer New York, 77--96. (10.1007/978-1-4939-2522-3_6) |
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Horigome, Chihiro, Oma, Yukako, Konishi, Tatsunori, Schmid, Roger, Marcomini, Isabella, Hauer, Michael H., Dion, Vincent, Harata, Masahiko and Gasser, Susan M. 2014. SWR1 and INO80 chromatin remodelers contribute to DNA double-strand break perinuclear anchorage site choice. Molecular Cell 55 (4) , 626--639. 10.1016/j.molcel.2014.06.027 |
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Krawczyk, Claudia, Dion, Vincent, Schar, Primo and Fritsch, Olivier
2014.
Reversible Top1 cleavage complexes are stabilized strand-specifically at the ribosomal replication fork barrier and contribute to ribosomal DNA stability.
Nucleic Acids Research
42
(8)
, 4985--4995.
10.1093/nar/gku148
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Seeber, Andrew, Dion, Vincent and Gasser, Susan M. 2014. Remodelers move chromatin in response to DNA damage. Cell Cycle 13 (6) , 877--878. 10.4161/cc.28200 |
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Dion, Vincent 2014. Tissue specificity in DNA repair: lessons from trinucleotide repeat instability. Trends in Genetics 30 (6) , 220--229. 10.1016/j.tig.2014.04.005 |
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Seeber, Andrew, Dion, Vincent and Gasser, Susan M. 2013. Checkpoint kinases and the INO80 nucleosome remodeling complex enhance global chromatin mobility in response to DNA damage. Genes {&} Development 27 (18) , 1999--2008. 10.1101/gad.222992.113 |
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Dion, Vincent and Gasser, Susan~M. 2013. Chromatin Movement in the Maintenance of Genome Stability. Cell 152 (6) , 1355--1364. 10.1016/j.cell.2013.02.010 |
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Dion, Vincent, Kalck, Véronique, Seeber, Andrew, Schleker, Thomas and Gasser, Susan M 2013. Cohesin and the nucleolus constrain the mobility of spontaneous repair foci. {EMBO} reports 14 (11) , 984--991. 10.1038/embor.2013.142 |
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Dion, Vincent, Kalck, Véronique, Horigome, Chihiro, Towbin, Benjamin D. and Gasser, Susan M. 2012. Increased mobility of double-strand breaks requires Mec1, Rad9 and the homologous recombination machinery. Nature Cell Biology 14 (5) , 502--509. 10.1038/ncb2465 |
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Neumann, Frank R., Dion, Vincent, Gehlen, Lutz R., Tsai-Pflugfelder, Monika, Schmid, Roger, Taddei, Angela and Gasser, Susan M. 2012. Targeted INO80 enhances subnuclear chromatin movement and ectopic homologous recombination. Genes {&} Development 26 (4) , 369--383. 10.1101/gad.176156.111 |
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Gehlen, Lutz R., Gasser, Susan M. and Dion, Vincent 2011. How Broken DNA Finds Its Template for Repair: A Computational Approach. Progress of Theoretical Physics Supplement 191 , 20--29. 10.1143/ptps.191.20 |
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Hubert, Leroy, Lin, Yunfu, Dion, Vincent and Wilson, John H. 2011. Topoisomerase 1 and Single-Strand Break Repair Modulate Transcription-Induced CAG Repeat Contraction in Human Cells. Molecular and Cellular Biology 31 (15) , 3105--3112. 10.1128/mcb.05158-11 |
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Hubert, L., Lin, Y., Dion, V. and Wilson, J. H. 2011. Xpa deficiency reduces CAG trinucleotide repeat instability in neuronal tissues in a mouse model of SCA1. Human Molecular Genetics 20 (24) , 4822--4830. 10.1093/hmg/ddr421 |
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Dion, Vincent, Shimada, Kenji and Gasser, Susan M 2010. Actin-related proteins in the nucleus: life beyond chromatin remodelers. Current Opinion in Cell Biology 22 (3) , 383--391. 10.1016/j.ceb.2010.02.006 |
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Dion, Vincent and Wilson, John H. 2009. Instability and chromatin structure of expanded trinucleotide repeats. Trends in Genetics 25 (7) , 288--297. 10.1016/j.tig.2009.04.007 |
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Bystricky, K., Attikum, H. Van, Montiel, M.-D., Dion, V., Gehlen, L. and Gasser, S. M. 2008. Regulation of Nuclear Positioning and Dynamics of the Silent Mating Type Loci by the Yeast Ku70/Ku80 Complex. Molecular and Cellular Biology 29 (3) , 835--848. 10.1128/mcb.01009-08 |
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Dion, V., Lin, Y., Hubert, L., Waterland, R. A. and Wilson, J. H. 2008. Dnmt1 deficiency promotes CAG repeat expansion in the mouse germline. Human Molecular Genetics 17 (9) , 1306--1317. 10.1093/hmg/ddn019 |
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Dion, Vincent, Lin, Yunfu, Price, Brandee A., Fyffe, Sharyl L., Seluanov, Andrei, Gorbunova, Vera and Wilson, John H. 2008. Genome-wide demethylation promotes triplet repeat instability independently of homologous recombination. {DNA} Repair 7 (2) , 313--320. 10.1016/j.dnarep.2007.11.002 |
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Lin, Yunfu, Dion, Vincent and Wilson, John H. 2006. Transcription and triplet repeat instability. Genetic instabilities and neurological diseases, Elsevier, p. 691. (10.1016/b978-012369462-1/50045-4) |
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Lin, Yunfu, Dion, Vincent and Wilson, John H. 2006. Transcription promotes contraction of CAG repeat tracts in human cells. Nature Structural {&} Molecular Biology 13 (2) , 179--180. 10.1038/nsmb1042 |
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Gorbunova, V., Seluanov, A., Dion, V., Sandor, Z., Meservy, J. L. and Wilson, J. H. 2003. Selectable System for Monitoring the Instability of CTG/CAG Triplet Repeats in Mammalian Cells. Molecular and Cellular Biology 23 (13) , 4485--4493. 10.1128/mcb.23.13.4485-4493.2003 |
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