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Number of items: 38.

Aston, Alys N. and Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637 2025. Interruptions impact clinical features of repeat expansion diseases, but how are they gained and lost? Trends in Genetics 10.1016/j.tig.2025.07.005
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Larin, Meghan, Gidney, Florence, Aeschbach, Lorene, Heraty, Laura, Randall, Emma, Heuchan, Aeverie, Buncova, Marcela, Berard, Melvin and Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637 2024. Cas9 nickase-mediated contractions of CAG/CTG repeats are transcription-dependent and replication-independent. NAR Molecular Medicine 1 (4) , ugae013. 10.1093/narmme/ugae013
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Murillo, Alvaro, Alpaugh, Melanie, Larin, Meghan, Randall, Emma L, Heraty, Laura, Durairaj, Ruban Rex, Aston, Alys N, Taylor, Alysha S, Monteys, Alex Mas, Stöberl, Nina, Heuchan, Aeverie ER, Aeschlimann, Pascale, Bhattacharyya, Soumyasree, Allen, Nicholas D ORCID: https://orcid.org/0000-0003-4009-186X, Puymirat, Jack, Davidson, Beverly L, Cicchetti, Francesca, Lelos, Mariah J ORCID: https://orcid.org/0000-0001-7102-055X and Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637 2024. I001 Cas9 nickase-mediated contraction of CAG repeats in Huntington’s disease. Journal of Neurology, Neurosurgery and Psychiatry 95 (Suppl) , A141-A142. 10.1136/jnnp-2024-EHDN.283

Mangin, Antoine, Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637 and Menzies, Georgina ORCID: https://orcid.org/0000-0002-6600-6507 2024. Developing small Cas9 hybrids using molecular modeling. Scientific Reports 14 (1) , 17233. 10.1038/s41598-024-68107-1
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Casella, Chiara, Kelly, B., Murillo Bartolome, Alvaro ORCID: https://orcid.org/0000-0001-5470-9347, Mills-Smith, B., Parker, G. D., Von Ruhland, Chris, Syed, Yasir Ahmed ORCID: https://orcid.org/0000-0001-9495-307X, Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637, Rosser, Anne E. ORCID: https://orcid.org/0000-0002-4716-4753, Metzler-Baddeley, Claudia ORCID: https://orcid.org/0000-0002-8646-1144, Jones, Derek K. ORCID: https://orcid.org/0000-0003-4409-8049 and Lelos, Mariah J. ORCID: https://orcid.org/0000-0001-7102-055X 2023. Differences in white matter detected by ex vivo 9.4T MRI are associated with axonal changes in the R6/1 model of Huntington’s Disease. [Online]. BioRXiv: BioRXiv. Available at: https://doi.org/10.1101/2023.10.02.560424
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Taylor, Alysha S., Barros, Dinis, Gobet, Nastassia, Schuepbach, Thierry, McAllister, Branduff, Aeschbach, Lorene, Randall, Emma L., Trofimenko, Evgeniya, Heuchan, Eleanor R., Barszcz, Paula, Ciosi, Marc, Morgan, Joanne, Hafford-Tear, Nathaniel J., Davidson, Alice E., Massey, Thomas H. ORCID: https://orcid.org/0000-0002-9804-2131, Monckton, Darren G., Jones, Lesley ORCID: https://orcid.org/0000-0002-3007-4612, network, REGISTRY Investigators of the European Huntington's disease, Xenarios, Ioannis and Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637 2022. Repeat Detector: versatile sizing of expanded tandem repeats and identification of interrupted alleles from targeted DNA sequencing. NAR Genomics and Bioinformatics 4 (4) , lqac089. 10.1093/nargab/lqac089
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Murillo, Alvaro, Larin, Meghan, Randall, Emma L, Taylor, Alysha, Lelos, Mariah ORCID: https://orcid.org/0000-0001-7102-055X and Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637 2022. I05 CRISPR-Cas9 nickase-mediated gene editing to treat Huntington’s disease. Journal of Neurology, Neurosurgery and Psychiatry 93 (Suppl) , A86. 10.1136/jnnp-2022-ehdn.231

Yang, Bin, Borgeaud, Alicia C., Buřičová, Marcela, Aeschbach, Lorène, Rodríguez-Lima, Oscar, Ruiz Buendía, Gustavo A., Cinesi, Cinzia, Taylor, Alysha S., Baubec, Tuncay and Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637 2022. Expanded CAGCTG repeats resist gene silencing mediated by targeted epigenome editing. Human Molecular Genetics 31 (3) , pp. 386-398. 10.1093/hmg/ddab255
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Wheeler, Vanessa and Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637 2021. Modifiers of CAG repeat instability: insights from mammalian models. Journal of Huntington's Disease 10 (1) , pp. 123-148. 10.3233/JHD-200426
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Ruiz Buendía, Gustavo A., Leleu, Marion, Marzetta, Flavia, Vanzan, Ludovica, Tan, Jennifer, Ythier, Victor, Randall, Emma L., Marques, Ana C., Baubec, Tuncay, Murr, Rabih, Xenarios, Ioannis and Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637 2020. Three-dimensional chromatin interactions remain stable upon CAG/CTG repeat expansion. Science Advances 6 (27) , eaaz4012. 10.1126/sciadv.aaz4012
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Cinesi, Cinzia, Yang, Bin and Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637 2019. GFP reporters to monitor instability and expression of expanded CAG/CTG repeats. Richard, Guy-Franck, ed. Trinucleotide Repeats: Methods and Protocols, Vol. 2056. Methods in Molecular Biology, Humana Press, pp. 255-268. (10.1007/978-1-4939-9784-8_16)

Malbec, Rémi, Chami, Bayan, Aeschbach, Lorène, Ruiz Buendía, Gustavo A., Socol, Marius, Joseph, Pierre, Leïchlé, Thierry, Trofimenko, Evgeniya, Bancaud, Aurélien and Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637 2019. µLAS: Sizing of expanded trinucleotide repeats with femtomolar sensitivity in less than 5 minutes. Scientific Reports 9 (1) , 23. 10.1038/s41598-018-36632-5
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Yang, Bin, Borgeaud, Alicia, Aeschbach, Lorene and Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637 2018. Uncovering the interplay between epigenome editing efficiency and sequence context using a novel inducible targeting system. [Online]. bioRxiv. Available at: https://doi.org/10.1101/368480
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Malbec, R., Chami, B., Ngo, H. H. T., Didelot, A., Garlan, F., Garrigou, S., Taly, V., Aeschbach, Lorene, Trofimenko, Evgeniya, Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637, Boutonnet-Rodat, A., Ginot, F. and Bancaud, A. 2018. Direct characterization of circulating DNA in blood plasma using μLAS technology. Presented at: IEEE International Electron Devices Meeting (IEDM 2017), San Francisco, CA, USA, 2-6 December 2017. 2017 IEEE International Electron Devices Meeting (IEDM). IEEE, 26.5.1-26.5.4. 10.1109/IEDM.2017.8268465
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Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637 and Aeschbach, Lorène 2017. Minimizing carry-over PCR contamination in expanded CAG/CTG repeat instability applications. Scientific Reports 7 , 18026. 10.1038/s41598-017-18168-2
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Cinesi, Cinzia, Aeschbach, Lorène, Yang, Bin and Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637 2016. Contracting CAG/CTG repeats using the CRISPR-Cas9 nickase. Nature Communications 7 , 13272. 10.1038/ncomms13272
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Su, Xiaofeng A., Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637, Gasser, Susan M. and Freudenreich, Catherine H. 2015. Regulation of recombination at yeast nuclear pores controls repair and triplet repeat stability. Genes {&} Development 29 (10) , 1006--1017. 10.1101/gad.256404.114

Horigome, Chihiro, Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637, Seeber, Andrew, Gehlen, Lutz R. and Gasser, Susan M. 2015. Visualizing the Spatiotemporal Dynamics of DNA Damage in Budding Yeast. Stress reponses, Methods in Molecular Biology, New York: Springer New York, 77--96. (10.1007/978-1-4939-2522-3_6)

Horigome, Chihiro, Oma, Yukako, Konishi, Tatsunori, Schmid, Roger, Marcomini, Isabella, Hauer, Michael H., Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637, Harata, Masahiko and Gasser, Susan M. 2014. SWR1 and INO80 chromatin remodelers contribute to DNA double-strand break perinuclear anchorage site choice. Molecular Cell 55 (4) , 626--639. 10.1016/j.molcel.2014.06.027

Krawczyk, Claudia, Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637, Schar, Primo and Fritsch, Olivier 2014. Reversible Top1 cleavage complexes are stabilized strand-specifically at the ribosomal replication fork barrier and contribute to ribosomal DNA stability. Nucleic Acids Research 42 (8) , 4985--4995. 10.1093/nar/gku148
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Seeber, Andrew, Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637 and Gasser, Susan M. 2014. Remodelers move chromatin in response to DNA damage. Cell Cycle 13 (6) , 877--878. 10.4161/cc.28200

Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637 2014. Tissue specificity in DNA repair: lessons from trinucleotide repeat instability. Trends in Genetics 30 (6) , 220--229. 10.1016/j.tig.2014.04.005

Seeber, Andrew, Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637 and Gasser, Susan M. 2013. Checkpoint kinases and the INO80 nucleosome remodeling complex enhance global chromatin mobility in response to DNA damage. Genes {&} Development 27 (18) , 1999--2008. 10.1101/gad.222992.113

Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637 and Gasser, Susan~M. 2013. Chromatin Movement in the Maintenance of Genome Stability. Cell 152 (6) , 1355--1364. 10.1016/j.cell.2013.02.010

Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637, Kalck, Véronique, Seeber, Andrew, Schleker, Thomas and Gasser, Susan M 2013. Cohesin and the nucleolus constrain the mobility of spontaneous repair foci. {EMBO} reports 14 (11) , 984--991. 10.1038/embor.2013.142

Neumann, Frank R., Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637, Gehlen, Lutz R., Tsai-Pflugfelder, Monika, Schmid, Roger, Taddei, Angela and Gasser, Susan M. 2012. Targeted INO80 enhances subnuclear chromatin movement and ectopic homologous recombination. Genes {&} Development 26 (4) , 369--383. 10.1101/gad.176156.111

Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637, Kalck, Véronique, Horigome, Chihiro, Towbin, Benjamin D. and Gasser, Susan M. 2012. Increased mobility of double-strand breaks requires Mec1, Rad9 and the homologous recombination machinery. Nature Cell Biology 14 (5) , 502--509. 10.1038/ncb2465

Gehlen, Lutz R., Gasser, Susan M. and Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637 2011. How Broken DNA Finds Its Template for Repair: A Computational Approach. Progress of Theoretical Physics Supplement 191 , 20--29. 10.1143/ptps.191.20

Hubert, Leroy, Lin, Yunfu, Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637 and Wilson, John H. 2011. Topoisomerase 1 and Single-Strand Break Repair Modulate Transcription-Induced CAG Repeat Contraction in Human Cells. Molecular and Cellular Biology 31 (15) , 3105--3112. 10.1128/mcb.05158-11

Hubert, L., Lin, Y., Dion, V. ORCID: https://orcid.org/0000-0003-4953-7637 and Wilson, J. H. 2011. Xpa deficiency reduces CAG trinucleotide repeat instability in neuronal tissues in a mouse model of SCA1. Human Molecular Genetics 20 (24) , 4822--4830. 10.1093/hmg/ddr421

Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637, Shimada, Kenji and Gasser, Susan M 2010. Actin-related proteins in the nucleus: life beyond chromatin remodelers. Current Opinion in Cell Biology 22 (3) , 383--391. 10.1016/j.ceb.2010.02.006

Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637 and Wilson, John H. 2009. Instability and chromatin structure of expanded trinucleotide repeats. Trends in Genetics 25 (7) , 288--297. 10.1016/j.tig.2009.04.007

Dion, V. ORCID: https://orcid.org/0000-0003-4953-7637, Lin, Y., Hubert, L., Waterland, R. A. and Wilson, J. H. 2008. Dnmt1 deficiency promotes CAG repeat expansion in the mouse germline. Human Molecular Genetics 17 (9) , 1306--1317. 10.1093/hmg/ddn019

Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637, Lin, Yunfu, Price, Brandee A., Fyffe, Sharyl L., Seluanov, Andrei, Gorbunova, Vera and Wilson, John H. 2008. Genome-wide demethylation promotes triplet repeat instability independently of homologous recombination. {DNA} Repair 7 (2) , 313--320. 10.1016/j.dnarep.2007.11.002

Bystricky, K., Attikum, H. Van, Montiel, M.-D., Dion, V. ORCID: https://orcid.org/0000-0003-4953-7637, Gehlen, L. and Gasser, S. M. 2008. Regulation of Nuclear Positioning and Dynamics of the Silent Mating Type Loci by the Yeast Ku70/Ku80 Complex. Molecular and Cellular Biology 29 (3) , 835--848. 10.1128/mcb.01009-08

Lin, Yunfu, Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637 and Wilson, John H. 2006. Transcription promotes contraction of CAG repeat tracts in human cells. Nature Structural {&} Molecular Biology 13 (2) , 179--180. 10.1038/nsmb1042

Lin, Yunfu, Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637 and Wilson, John H. 2006. Transcription and triplet repeat instability. Genetic instabilities and neurological diseases, Elsevier, p. 691. (10.1016/b978-012369462-1/50045-4)

Gorbunova, V., Seluanov, A., Dion, V. ORCID: https://orcid.org/0000-0003-4953-7637, Sandor, Z., Meservy, J. L. and Wilson, J. H. 2003. Selectable System for Monitoring the Instability of CTG/CAG Triplet Repeats in Mammalian Cells. Molecular and Cellular Biology 23 (13) , 4485--4493. 10.1128/mcb.23.13.4485-4493.2003

This list was generated on Thu Oct 23 15:20:19 2025 BST.


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