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Number of items: 43.

Clark, Branden J., Lelos, Mariah J. ORCID: https://orcid.org/0000-0001-7102-055X and Loring, Jeanne F. 2024. Advancing Parkinson’s disease treatment: cell replacement therapy with neurons derived from pluripotent stem cells. Stem Cells 42 (9) , pp. 781-790. 10.1093/stmcls/sxae042

Hennegan, James, Bryant, Aled, Griffiths, Lauren, Trigano, Matthieu, Bartley, Oliver J. M., Bartlett, Joanna, Minahan, Carys, Abreu de Oliveira, Willy Antoni, Yutuc, Eylan, Ntikas, Sotiros, Bartsocas, Christos, Markouri, Margarita, Antoniadou, Eleni, Laina, Ioanna, Howell, Owain, Li, Meng ORCID: https://orcid.org/0000-0002-4803-4643, Wang, Yuqin, Griffiths, William, Lane, Emma L. ORCID: https://orcid.org/0000-0001-8800-3764, Lelos, Mariah ORCID: https://orcid.org/0000-0001-7102-055X and Theofilopoulos, Spyridon 2024. Inhibition of 7α,26-dihydroxycholesterol biosynthesis promotes midbrain dopaminergic neuron development. iScience 27 (1) , 108670. 10.1016/j.isci.2023.108670
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Lelos, Mariah J. ORCID: https://orcid.org/0000-0001-7102-055X, Murphy, Ellen M., Lindgren, Hanna S., Dunnett, Stephen B. ORCID: https://orcid.org/0000-0003-1826-1578 and Lane, Emma L. ORCID: https://orcid.org/0000-0001-8800-3764 2023. Impaired cognitive and motor function are coincident with l -DOPA-induced dyskinesia in a model of Parkinson’s disease. Scientific Reports 13 , 17697. 10.1038/s41598-023-44869-y
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Indrigo, Marzia, Morella, Ilaria ORCID: https://orcid.org/0000-0001-5691-5400, Orellana, Daniel, d'Isa, Raffaele, Papale, Alessandro ORCID: https://orcid.org/0000-0002-8794-0171, Parra, Riccardo, Gurgone, Antonia, Lecca, Daniela, Cavaccini, Anna, Tigaret, Cezar M. ORCID: https://orcid.org/0000-0001-5848-6697, Cagnotto, Alfredo, Jones, Kimberley, Brooks, Simon ORCID: https://orcid.org/0000-0001-9853-6177, Ratto, Gian Michele, Allen, Nicholas D. ORCID: https://orcid.org/0000-0003-4009-186X, Lelos, Mariah J. ORCID: https://orcid.org/0000-0001-7102-055X, Middei, Silvia, Giustetto, Maurizio, Carta, Anna R., Tonini, Raffaella, Salmona, Mario, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009, Thomas, Kerrie ORCID: https://orcid.org/0000-0003-3355-9583, Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706 and Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139 2023. Nuclear ERK1/2 signaling potentiation enhances neuroprotection and cognition via Importinα1/KPNA2. EMBO Molecular Medicine 15 (11) , e15984. 10.15252/emmm.202215984
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Casella, Chiara, Kelly, B., Murillo Bartolome, Alvaro ORCID: https://orcid.org/0000-0001-5470-9347, Mills-Smith, B., Parker, G. D., Von Ruhland, Chris, Syed, Yasir Ahmed ORCID: https://orcid.org/0000-0001-9495-307X, Dion, Vincent ORCID: https://orcid.org/0000-0003-4953-7637, Rosser, Anne E. ORCID: https://orcid.org/0000-0002-4716-4753, Metzler-Baddeley, Claudia ORCID: https://orcid.org/0000-0002-8646-1144, Jones, Derek K. ORCID: https://orcid.org/0000-0003-4409-8049 and Lelos, Mariah J. ORCID: https://orcid.org/0000-0001-7102-055X 2023. Differences in white matter detected by ex vivo 9.4T MRI are associated with axonal changes in the R6/1 model of Huntington’s Disease. [Online]. BioRXiv: BioRXiv. Available at: https://doi.org/10.1101/2023.10.02.560424
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Clinch, S. P., Busse, M., Griffiths, J., Rosser, A.E. ORCID: https://orcid.org/0000-0002-4716-4753 and Lelos, M.J. ORCID: https://orcid.org/0000-0001-7102-055X 2023. Identification of the neural correlates underlying conflict resolution performance using a rodent analogue of the Stroop tests. Neuroscience 524 , pp. 79-88. 10.1016/j.neuroscience.2023.05.024
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Rees, Daniel, Beynon, Amy L., Lelos, Mariah J. ORCID: https://orcid.org/0000-0001-7102-055X, Smith, Gaynor A. ORCID: https://orcid.org/0000-0003-4332-8383, Roberts, Luke D., Phelps, Lyndsey, Dunnett, Stephen B. ORCID: https://orcid.org/0000-0003-1826-1578, Morgan, Alwena H., Brown, Rowan M., Wells, Timothy ORCID: https://orcid.org/0000-0003-3618-0595 and Davies, Jefrey S. 2023. Acyl-ghrelin attenuates neurochemical and motor deficits in the 6-OHDA model of Parkinson’s Disease. Cellular and Molecular Neurobiology 43 , pp. 2377-2384. 10.1007/s10571-022-01282-9
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Hills, Rachel, Mossman, Jim A., Bratt-Leal, Andres M., Tran, Ha, Williams, Roy M., Stouffer, David G., Sokolova, Irina V., Sanna, Pietro P., Loring, Jeanne F. and Lelos, Mariah J. ORCID: https://orcid.org/0000-0001-7102-055X 2023. Neurite outgrowth and gene expression profile correlate with efficacity of human induced pluripotent stem cell-derived dopamine neuron grafts. Stem Cells and Development 32 (13-14) , pp. 387-397. 10.1089/scd.2023.0043
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Jareno, Patricia Garcia, Bartley, Oliver, Precious, Sophie, Rosser, Anne ORCID: https://orcid.org/0000-0002-4716-4753 and Lelos, Mariah ORCID: https://orcid.org/0000-0001-7102-055X 2022. Challenges in progressing cell therapies to the clinic for Huntington's disease: A review of the progress made with pluripotent stem cell derived medium spiny neurons. Lane, Emma L., Drew, Cheney and Lelos, Mariah J., eds. International Review of Neurobiology: Current Challenges in Cell Therapy for Neurodegenerative Diseases, Vol. 166. Elsevier, pp. 1-48. (10.1016/bs.irn.2022.09.003)

Lelos, Mariah J. ORCID: https://orcid.org/0000-0001-7102-055X 2022. Investigating cell therapies in animal models of Parkinson's and Huntington's disease: current challenges and considerations. Lane, Emma L., Drew, Cheney and Lelos, Mariah J., eds. International Review of Neurobiology, Vol. 166. Elsevier, pp. 158-189. (10.1016/bs.irn.2022.09.005)

Lane, Emma L. ORCID: https://orcid.org/0000-0001-8800-3764 and Lelos, Mariah J. ORCID: https://orcid.org/0000-0001-7102-055X 2022. Defining the unknowns for cell therapies in Parkinson's disease. Disease Models and Mechanisms 15 (10) , dmm049543. 10.1242/dmm.049543
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Sap, Jeroen B. I., Meyer, Claudio F., Ford, Joseph, Straathof, Natan J. W., Dürr, Alexander B., Lelos, Mariah J. ORCID: https://orcid.org/0000-0001-7102-055X, Paisey, Stephen J., Mollner, Tim A., Hell, Sandrine M., Trabanco, Andrés A., Genicot, Christophe, am Ende, Christopher W., Paton, Robert S., Tredwell, Matthew ORCID: https://orcid.org/0000-0002-4184-5611 and Gouverneur, Véronique 2022. [18F]Difluorocarbene for Positron Emission Tomography. Nature 606 , pp. 102-108. 10.1038/s41586-022-04669-2
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Lelos, Mariah J. ORCID: https://orcid.org/0000-0001-7102-055X 2022. Can cell and gene therapies improve cognitive symptoms in Parkinson's disease? Journal of Integrative Neuroscience 21 (3) , 78. 10.31083/j.jin2103078
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Lane, Emma L. ORCID: https://orcid.org/0000-0001-8800-3764, Harrison, David J., Ramos-Varas, Elena, Hills, Rachel, Turner, Sophie and Lelos, Mariah J. ORCID: https://orcid.org/0000-0001-7102-055X 2022. Spontaneous graft-induced dyskinesias are independent of 5-HT neurons and levodopa priming in a model of Parkinson's disease. Movement Disorders 37 (3) , pp. 613-619. 10.1002/mds.28856
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Bartley, Oliver J M, Lelos, Mariah J ORCID: https://orcid.org/0000-0001-7102-055X, Gray, William P ORCID: https://orcid.org/0000-0001-7595-8887 and Rosser, Anne E ORCID: https://orcid.org/0000-0002-4716-4753 2021. Do foetal transplant studies continue to be justified in Huntington's disease? Neuronal Signaling 5 , acerbic. 10.1042/NS20210019
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Lelos, Mariah ORCID: https://orcid.org/0000-0001-7102-055X 2020. Overview of Alzheimer's and Parkinson's diseases and the role of protein aggregation in these neurodegenerative diseases. Salgado, Antonio J., ed. Handbook of Innovations in Central Nervous System Regenerative Medicine, Elsevier, pp. 29-53. (doi.org/10.1016/B978-0-12-818084-6.00002-7)

Lelos, Mariah J. ORCID: https://orcid.org/0000-0001-7102-055X and Dunnett, Stephen B. 2018. Generating excitotoxic lesion models of Huntington’s Disease. Precious, Sophie V., Rosser, Anne E. and Dunnett, Stephen B., eds. Huntington’s Disease, Methods in Molecular Biology, New York, NY, USA: pp. 209-220. (10.1007/978-1-4939-7825-0_11)

Clinch, Susanne P., Busse, Monica, Lelos, Mariah J. ORCID: https://orcid.org/0000-0001-7102-055X and Rosser, Anne E. ORCID: https://orcid.org/0000-0002-4716-4753 2018. Rethinking functional outcome measures: the development of an upper limb test to assess basal ganglia dysfunction. Frontiers in Neuroscience 12 , 366. 10.3389/fnins.2018.00366
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Kirkeby, Agnete, Nolbrant, Sara, Tiklova, Katarina, Heuer, Andreas, Kee, Nigel, Cardoso, Tiago, Rylander Ottosson, Daniella, Lelos, Mariah J. ORCID: https://orcid.org/0000-0001-7102-055X, Rifes, Pedro, Dunnett, Stephen B. ORCID: https://orcid.org/0000-0003-1826-1578, Grealish, Shane, Perlmann, Thomas and Parmar, Malin 2017. Predictive markers guide differentiation to improve graft outcome in clinical translation of hESC-based therapy for Parkinson's disease. Cell Stem Cell 20 (1) , pp. 135-148. 10.1016/j.stem.2016.09.004
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Yhnell, Emma ORCID: https://orcid.org/0000-0003-3960-5181, Lelos, Mariah Jillian ORCID: https://orcid.org/0000-0001-7102-055X, Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 and Brooks, Simon Philip ORCID: https://orcid.org/0000-0001-9853-6177 2016. L30 Cognitive training improves disease symptoms in a mouse model of huntington's disease. Journal of Neurology, Neurosurgery & Psychiatry 87 (Supp 1) , A100-A101. 10.1136/jnnp-2016-314597.285

Yhnell, Emma ORCID: https://orcid.org/0000-0003-3960-5181, Lelos, Mariah Jillian ORCID: https://orcid.org/0000-0001-7102-055X, Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 and Brooks, Simon Philip ORCID: https://orcid.org/0000-0001-9853-6177 2016. Cognitive training modifies disease symptoms in a mouse model of Huntington's disease. Experimental Neurology 282 , pp. 19-26. 10.1016/j.expneurol.2016.05.008
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Harvey, Ann K, Lelos, Mariah Jillian ORCID: https://orcid.org/0000-0001-7102-055X, Greenhill, Claire J., Jones, Ashley, Clinch, Susanne, Newton, Michael, Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578, Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2016. Novel application of behavioral assays allows dissociation of joint pathology from systemic extra-articular alterations induced by inflammatory arthritis. Journal of Rheumatic Diseases and Treatment 2 (2) , 033. 10.23937/2469-5726/1510033
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Lelos, Mariah ORCID: https://orcid.org/0000-0001-7102-055X, Morgan, R. J., Kelly, Claire, Torres, Eduardo Miguel, Rosser, Anne Elizabeth ORCID: https://orcid.org/0000-0002-4716-4753 and Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 2016. Amelioration of non-motor dysfunctions after transplantation of human dopamine neurons in a model of Parkinson's disease. Experimental Neurology 278 , pp. 54-61. 10.1016/j.expneurol.2016.02.003
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Lelos, Mariah Jillian ORCID: https://orcid.org/0000-0001-7102-055X, Roberton, Victoria H., Vinh, Ngoc-Nga, Harrison, Carl, Eriksen, P., Torres, Eduardo, Clinch, Susanne, Rosser, Anne Elizabeth ORCID: https://orcid.org/0000-0002-4716-4753 and Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 2016. Direct comparison of rat- and human-derived ganglionic eminence tissue grafts on motor function. Cell Transplantation 25 , pp. 665-675. 10.3727/096368915X690297
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Lelos, Mariah J. ORCID: https://orcid.org/0000-0001-7102-055X and Good, Mark A. ORCID: https://orcid.org/0000-0002-1824-1203 2014. β-Amyloid pathology alters neural network activation during retrieval of contextual fear memories in a mouse model of Alzheimer's disease. European Journal of Neuroscience 39 (10) , pp. 1690-1703. 10.1111/ejn.12527

Murphy, Ellen M., Lelos, Mariah Jillian ORCID: https://orcid.org/0000-0001-7102-055X, O'Neill, Michael J., Lane, Emma Louise ORCID: https://orcid.org/0000-0001-8800-3764 and Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 2013. Long-term restorative effects of bromocriptine on operant responding in the 6-hydroxydopamine-lesioned rat. NeuroReport 24 (18) , pp. 1019-1024. 10.1097/WNR.0000000000000060

Heuer, Andreas ORCID: https://orcid.org/0000-0003-0300-7606, Lelos, Mariah Jillian ORCID: https://orcid.org/0000-0001-7102-055X, Kelly, Claire, Torres, Eduardo Miguel and Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 2013. Dopamine-rich grafts alleviate deficits in contralateral response space induced by extensive dopamine depletion in rats. Experimental Neurology 247 , pp. 485-495. 10.1016/j.expneurol.2013.01.020

Lelos, Mariah Jillian ORCID: https://orcid.org/0000-0001-7102-055X, Lane, Emma ORCID: https://orcid.org/0000-0001-8800-3764 and Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 2013. What helps can also hinder: A dissociation in the acute effect of levodopa treatment on motor and cognitive functions. Movement Disorders 28 (5) , pp. 563-564. 10.1002/mds.25294

Carri, Alessia Delli, Onorati, Marco, Lelos, Mariah Jillian ORCID: https://orcid.org/0000-0001-7102-055X, Castiglioni, Valentina, Faedo, Andrea, Menon, Ramesh, Camnasio, Stefano, Vuono, Romina, Spaiardi, Paolo, Talpo, Francesca, Toselli, Mauro, Martino, Gianvito, Barker, Roger A., Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578, Biella, Gerardo and Cattaneo, Elena 2013. Developmentally coordinated extrinsic signals drive human pluripotent stem cell differentiation toward authentic DARPP-32(+) medium-sized spiny neurons. Development 140 (2) , pp. 301-312. 10.1242/dev.084608

Lelos, Mariah Jillian ORCID: https://orcid.org/0000-0001-7102-055X, Harrison, David John, Rosser, Anne Elizabeth ORCID: https://orcid.org/0000-0002-4716-4753 and Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 2013. The lateral neostriatum is necessary for compensatory ingestive behaviour after intravascular dehydration in female rats. Appetite 71 , pp. 287-294. 10.1016/j.appet.2013.09.003

Trueman, R. C., Klein, A., Lindgren, H. S., Lelos, Mariah Jillian ORCID: https://orcid.org/0000-0001-7102-055X and Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 2013. Repair of the CNS using endogenous and transplanted neural stem cells. Current Topics in Behavioural Neurosciences 15 , pp. 357-398. 10.1007/7854_2012_223

Lelos, Mariah Jillian ORCID: https://orcid.org/0000-0001-7102-055X, Harrison, David John and Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 2012. Intrastriatal excitotoxic lesion or dopamine depletion of the neostriatum differentially impairs response execution in extrapersonal space. European Journal of Neuroscience 36 (10) , pp. 3420-3428. 10.1111/j.1460-9568.2012.08256.x

Lindgren, Hanna S., Lelos, Mariah Jillian ORCID: https://orcid.org/0000-0001-7102-055X and Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 2012. Do alpha-synuclein vector injections provide a better model of Parkinson's disease than the classic 6-hydroxydopamine model? Experimental Neurology 237 (1) , pp. 36-42. 10.1016/j.expneurol.2012.05.022

Lelos, Mariah Jillian ORCID: https://orcid.org/0000-0001-7102-055X and Good, Mark Andrew ORCID: https://orcid.org/0000-0002-1824-1203 2012. c-Fos expression reveals aberrant neural network activity during cued fear conditioning in APPswe transgenic mice. Neurobiology of Learning and Memory 98 (1) , pp. 1-11. 10.1016/j.nlm.2012.03.001

Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578, Heuer, Andreas ORCID: https://orcid.org/0000-0003-0300-7606, Lelos, Mariah Jillian ORCID: https://orcid.org/0000-0001-7102-055X, Brooks, Simon Philip ORCID: https://orcid.org/0000-0001-9853-6177 and Rosser, Anne Elizabeth ORCID: https://orcid.org/0000-0002-4716-4753 2012. Bilateral striatal lesions disrupt performance in an operant delayed reinforcement task in rats. Brain Research Bulletin 88 (2-3) , pp. 251-260. 10.1016/j.brainresbull.2011.04.002

Heuer, Andreas ORCID: https://orcid.org/0000-0003-0300-7606, Smith, Gaynor A. ORCID: https://orcid.org/0000-0003-4332-8383, Lelos, Mariah Jillian ORCID: https://orcid.org/0000-0001-7102-055X, Lane, Emma Louise ORCID: https://orcid.org/0000-0001-8800-3764 and Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 2012. Unilateral nigrostriatal 6-hydroxydopamine lesions in mice I: Motor impairments identify extent of dopamine depletion at three different lesion sites. Behavioural Brain Research 228 (1) , pp. 30-43. 10.1016/j.bbr.2011.11.027

Lelos, Mariah Jillian ORCID: https://orcid.org/0000-0001-7102-055X, Dowd, Eilís and Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 2012. Nigral grafts in animal models of Parkinson's disease. Is recovery beyond motor function possible? Progress in Brain Research, Vol. 200. Elsevier, pp. 113-142. (10.1016/B978-0-444-59575-1.00006-5)

Lelos, Mariah Jillian ORCID: https://orcid.org/0000-0001-7102-055X, Harrison, David John and Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 2011. Impaired sensitivity to Pavlovian stimulus-outcome learning after excitotoxic lesion of the ventrolateral neostriatum. Behavioural Brain Research 225 (2) , pp. 522-528. 10.1016/j.bbr.2011.08.017

Thomas, Rhian Sara, Lelos, Mariah Jillian ORCID: https://orcid.org/0000-0001-7102-055X, Good, Mark Andrew ORCID: https://orcid.org/0000-0002-1824-1203 and Kidd, Emma Jane ORCID: https://orcid.org/0000-0001-5507-1170 2011. Clathrin-mediated endocytic proteins are upregulated in the cortex of the Tg2576 mouse model of Alzheimer's disease-like amyloid pathology. Biochemical and Biophysical Research Communications 415 (4) , pp. 656-661. 10.1016/j.bbrc.2011.10.131

Lelos, Mariah Jillian ORCID: https://orcid.org/0000-0001-7102-055X, Thomas, Rhian Sara, Kidd, Emma Jane ORCID: https://orcid.org/0000-0001-5507-1170 and Good, Mark Andrew ORCID: https://orcid.org/0000-0002-1824-1203 2011. Outcome-specific satiety reveals a deficit in context-outcome, but not stimulus-or action-outcome, associations in aged Tg2576 mice. Behavioral Neuroscience 125 (3) , pp. 412-425. 10.1037/a0023415

Lelos, Mariah Jillian ORCID: https://orcid.org/0000-0001-7102-055X and Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 2011. Aberrant dopamine transmission and cognitive dysfunction in animal models of Parkinson's disease. Journal of Parkinson's Disease 1 (2) , pp. 151-165.

Lelos, Mariah Jillian ORCID: https://orcid.org/0000-0001-7102-055X 2010. Influence of beta-amyloid pathology on emotional learning and memory in the APPswe model of Alzheimer's disease. PhD Thesis, Cardiff University.
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Dunnett, Stephen B. ORCID: https://orcid.org/0000-0003-1826-1578 and Lelos, Mariah ORCID: https://orcid.org/0000-0001-7102-055X 2010. Behavioural analysis of motor and non-motor symptoms in rodent models of Parkinson’s disease. Progress in Brain Research, Vol. 184. Elsevier, pp. 35-51. (10.1016/S0079-6123(10)84003-8)

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