Hinchly, Taylor, Bonnet, Dominique and Anjos Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X
2025.
Methodological considerations on how to identify human hematopoietic stem cells.
Experimental Hematology: Journal for Hematology, Stem Cell Biology and Transplantation
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, 104729.
10.1016/j.exphem.2025.104729
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Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X and Bonnet, Dominique
2023.
Human CD34+ hematopoietic stem cell hierarchy: how far are we with its delineation at the most primitive level?
Blood
142
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, pp. 509-518.
10.1182/blood.2022018071
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Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Buettner, Florian, Mian, Syed A., Rhys, Hefin, Perez-Lloret, Jimena, Garcia-Albornoz, Manuel, Rastogi, Namrata, Ariza-McNaughton, Linda and Bonnet, Dominique
2022.
Single cell analyses identify a highly regenerative and homogenous human CD34+ hematopoietic stem cell population.
Nature Communications
13
, 2048.
10.1038/s41467-022-29675-w
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Mian, Syed A., Dos Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X and Bonnet, Dominique
2021.
Advances in human immune system mouse models for studying human hematopoiesis and cancer immunotherapy.
Frontiers in Immunology
11
, 619236.
10.3389/fimmu.2020.619236
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Caye, Aurélie, Rouault-Pierre, Kevin, Strullu, Marion, Lainey, Elodie, Abarrategi, Ander, Fenneteau, Odile, Arfeuille, Chloé, Osman, Jennifer, Cassinat, Bruno, Pereira, Sabrina, Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Currie, Erin, Ariza-McNaughton, Linda, Barlogis, Vincent, Dalle, Jean-Hugues, Baruchel, André, Chomienne, Christine, Cavé, Hélène and Bonnet, Dominique
2020.
Despite mutation acquisition in hematopoietic stem cells, JMML-propagating cells are not always restricted to this compartment.
Leukemia
34
, pp. 1658-1668.
10.1038/s41375-019-0662-y
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Lopez-Millan, Belen, Diaz de la Guardia, Rafael, Roca-Ho, Heleia, Anguita, Eduardo, Islam, Abul B. M. M. K., Romero-Moya, Damia, Prieto, Cristina, Gutierrez-Agüera, Francisco, Bejarano-Garcia, Jose Antonio, Perez-Simon, Jose Antonio, Costales, Paula, Rovira, Montse, Marín, Pedro, Menendez, Silvia, Iglesias, Mar, Fuster, Jose Luis, Urbano-Ispizua, Alvaro, Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Bueno, Clara and Menendez, Pablo
2018.
IMiDs mobilize acute myeloid leukemia blasts to peripheral blood through downregulation of CXCR4 but fail to potentiate AraC/Idarubicin activity in preclinical models of non del5q/5q- AML.
OncoImmunology
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, e1477460.
10.1080/2162402X.2018.1477460
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Helft, Julie, Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, van der Veen, Annemarthe G., Chakravarty, Probir, Bonnet, Dominique and Reis e Sousa, Caetano
2017.
Dendritic cell lineage potential in human early hematopoietic progenitors.
Cell Reports
20
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, pp. 529-537.
10.1016/j.celrep.2017.06.075
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Lampreia, Fabio Pereira, Carmelo, Joana Gonçalves and Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X
2017.
Notch signaling in the regulation of hematopoietic stem cell.
Current Stem Cell Reports
10.1007/s40778-017-0090-8
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Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Loizou, Joanna I., Bradburn, Amy, Kanu, Nnennaya, Purewal, Sukhveer, Da Costa, Clive, Bonnet, Dominique and Behrens, Axel
2016.
Perturbed hematopoiesis in mice lacking ATMIN.
Blood
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, pp. 2017-2021.
10.1182/blood-2015-09-672980
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Griessinger, Emmanuel, Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Vargaftig, Jacques, Taussig, David C., Lassailly, Francois, Prebet, Thomas, Imbert, Veronique, Nebout, Marielle, Vey, Norbert, Chabannon, Christian, Filby, Andrew, Bollet-Quivogne, Frederic, Gribben, John G., Peyron, Jean-Francois and Bonnet, Dominique
2016.
Frequency and dynamics of leukemia-initiating cells during short-term ex vivo culture informs outcomes in acute myeloid leukemia patients.
Cancer Research
76
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, pp. 2082-2086.
10.1158/0008-5472.CAN-15-2063
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Foster, Katie, Lassailly, François, Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Currie, Erin, Rouault-Pierre, Kevin and Bonnet, Dominique
2015.
Different motile behaviors of human hematopoietic stem versus progenitor cells at the osteoblastic niche.
Stem Cell Reports
5
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, pp. 690-701.
10.1016/j.stemcr.2015.09.003
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Miraki-Moud, Farideh, Ghazaly, Essam, Ariza-McNaughton, Linda, Hodby, Katharine A., Clear, Andrew, Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Liapis, Konstantinos, Grantham, Marianne, Sohrabi, Fareeda, Cavenagh, Jamie, Bomalaski, John S., Gribben, John G., Szlosarek, Peter W., Bonnet, Dominique and Taussig, David C.
2015.
Arginine deprivation using pegylated arginine deiminase has activity against primary acute myeloid leukemia cells in vivo.
Blood
125
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, pp. 4060-4068.
10.1182/blood-2014-10-608133
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Costello, Patrick, Sargent, Mathew, Maurice, Diane, Esnault, Cyril, Foster, Katie, Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X and Treisman, Richard
2015.
MRTF-SRF signaling is required for seeding of HSC/Ps in bone marrow during development.
Blood
125
(8)
, pp. 1244-1255.
10.1182/blood-2014-08-595603
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Niavarani, Ahmadreza, Currie, Erin, Reyal, Yasmin, Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Horswell, Stuart, Griessinger, Emmanuel, Luis Sardina, Jose and Bonnet, Dominique
2015.
APOBEC3A is implicated in a novel class of G-to-A mRNA editing in WT1 transcripts.
PLoS ONE
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, e0120089.
10.1371/journal.pone.0120089
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Pizzitola, I., Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Rouault-Pierre, K., Lassailly, F., Tettamanti, S., Spinelli, O., Biondi, A., Biagi, E. and Bonnet, D.
2014.
Chimeric antigen receptors against CD33/CD123 antigens efficiently target primary acute myeloid leukemia cells in vivo.
Leukemia
28
, pp. 1596-1605.
10.1038/leu.2014.62
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Griessinger, E., Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Pizzitola, I., Rouault-Pierre, K., Vargaftig, J., Taussig, D., Gribben, J., Lassailly, F. and Bonnet, Dominique
2014.
A niche-like culture system allowing the maintenance of primary human acute myeloid leukemia-initiating cells: A new tool to decipher their chemoresistance and self-renewal mechanisms.
Stem Cells Translational Medicine
3
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, pp. 520-529.
10.5966/sctm.2013-0166
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Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X and Bonnet, Dominique
2014.
Forgotten gems.
Cell Cycle
13
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, pp. 503-504.
10.4161/cc.27788
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Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Currie, Erin, Palmer, Hector G., Foster, Katie E., Taussig, David C. and Bonnet, Dominique
2013.
CD34− cells at the apex of the human hematopoietic stem cell hierarchy have distinctive cellular and molecular signatures.
Cell Stem Cell
13
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, pp. 161-174.
10.1016/j.stem.2013.05.025
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Miraki-Moud, F., Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Hodby, K. A., Griessinger, E., Rosignoli, G., Lillington, D., Jia, L., Davies, J. K., Cavenagh, J., Smith, M., Oakervee, H., Agrawal, S., Gribben, J. G., Bonnet, Dominique and Taussig, D. C.
2013.
Acute myeloid leukemia does not deplete normal hematopoietic stem cells but induces cytopenias by impeding their differentiation.
Proceedings of the National Academy of Sciences of the United States of America
110
(33)
, pp. 13576-13581.
10.1073/pnas.1301891110
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Jaganathan, Bithiah, Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Kumar, Atul and Bonnet, Dominique
2013.
Active RHOA favors retention of human hematopoietic stem/progenitor cells in their niche.
Journal of Biomedical Science
20
(1)
, 66.
10.1186/1423-0127-20-66
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Rouault-Pierre, Kevin, Lopez-Onieva, Lourdes, Foster, Katie, Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Lamrissi-Garcia, Isabelle, Serrano-Sanchez, Martin, Mitter, Richard, Ivanovic, Zoran, de Verneuil, Hubert, Gribben, John, Taussig, David, Rezvani, Hamid Reza, Mazurier, Frédéric and Bonnet, Dominique
2013.
HIF-2α protects human hematopoietic stem/progenitors and acute myeloid leukemic cells from apoptosis induced by endoplasmic reticulum stress.
Cell Stem Cell
13
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, pp. 549-563.
10.1016/j.stem.2013.08.011
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Kallinikou, Konstantina, Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Blundell, Michael P., Ings, Stuart J., Watts, Michael J., Thrasher, Adrian J., Linch, David C., Bonnet, Dominique and Yong, Kwee L.
2012.
Engraftment defect of cytokine-cultured adult human mobilized CD34+ cells is related to reduced adhesion to bone marrow niche elements.
British Journal of Haematology
158
(6)
, pp. 778-787.
10.1111/j.1365-2141.2012.09219.x
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Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X and Bonnet, Dominique
2011.
Prospective identification and isolation of murine bone marrow derived multipotent mesenchymal progenitor cells.
Best Practice & Research Clinical Haematology
24
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, pp. 13-24.
10.1016/j.beha.2010.11.003
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Vargaftig, J., Taussig, D. C., Griessinger, E., Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Lister, T. A., Cavenagh, J., Oakervee, H., Gribben, J. and Bonnet, Dominique
2011.
Frequency of leukemic initiating cells does not depend on the xenotransplantation model used.
Leukemia
26
(4)
, pp. 858-860.
10.1038/leu.2011.250
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Poulin, L. F., Salio, M., Griessinger, E., Anjos-Afonso, F. ORCID: https://orcid.org/0000-0003-4392-488X, Craciun, L., Chen, J. -L., Keller, A. M., Joffre, O., Zelenay, S., Nye, E., Le Moine, A., Faure, F., Donckier, V., Sancho, D., Cerundolo, V., Bonnet, D. and Reis e Sousa, C.
2010.
Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8 + dendritic cells.
Journal of Experimental Medicine
207
(6)
, pp. 1261-1271.
10.1084/jem.20092618
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Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X and Bonnet, Dominique
2008.
Isolation, culture, and differentiation potential of mouse marrow stromal cells.
Current Protocols in Stem Cell Biology
10.1002/9780470151808.sc02b03s7
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Pálmer, Héctor G., Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Carmeliet, Geert, Takeda, Hikaru and Watt, Fiona M.
2008.
The vitamin D receptor is a Wnt effector that controls hair follicle differentiation and specifies tumor type in adult epidermis.
PLoS ONE
3
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, e1483.
10.1371/journal.pone.0001483
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Taussig, D. C., Miraki-Moud, F., Anjos-Afonso, F. ORCID: https://orcid.org/0000-0003-4392-488X, Pearce, D. J., Allen, K., Ridler, C., Lillington, D., Oakervee, H., Cavenagh, J., Agrawal, S. G., Lister, T. A., Gribben, J. G. and Bonnet, D.
2008.
Anti-CD38 antibody-mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells.
Blood -New York-
112
(3)
, pp. 568-575.
10.1182/blood-2007-10-118331
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Pearce, Daniel J., Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Ridler, Christopher M., Eddaoudi, Ayad and Bonnet, Dominique
2007.
Age-dependent increase in side population distribution within hematopoiesis: implications for our understanding of the mechanism of aging.
Stem Cells
25
(7)
, p. 1852.
10.1634/stemcells.2006-0405erratum
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Pearce, Daniel J., Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Ridler, Christopher M., Eddaoudi, Ayad and Bonnet, Dominique
2007.
Age-dependent increase in side population distribution within hematopoiesis: Implications for our understanding of the mechanism of aging.
Stem Cells
25
(4)
, pp. 828-835.
10.1634/stemcells.2006-0405
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Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X and Bonnet, Dominique
2007.
Flexible and dynamic organization of bone marrow stromal compartment.
British Journal of Haematology
139
(3)
, pp. 373-384.
10.1111/j.1365-2141.2007.06827.x
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Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X and Bonnet, Dominique
2006.
Nonhematopoietic/endothelial SSEA-1+ cells define the most primitive progenitors in the adult murine bone marrow mesenchymal compartment.
Blood
109
(3)
, pp. 1298-1306.
10.1182/blood-2006-06-030551
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Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Siapati, Elena K. and Bonnet, Dominique
2004.
In vivo contribution of murine mesenchymal stem cells into multiple cell-types under minimal damage conditions.
Journal of Cell Science
117
(23)
, pp. 5655-5664.
10.1242/jcs.01488
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