Dart, D. Alwyn, Bevan, Charlotte L., Uysal-Onganer, Pinar and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2024. Analysis of androgen receptor expression and activity in the mouse brain. Scientific Reports 14 (1) , 11115. 10.1038/s41598-024-61733-9 |
Lanning, Ben, Webber, Jason ORCID: https://orcid.org/0000-0003-4772-3014, Uysal-Ongane, Pinar, Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 and Dart, Dafydd Alwyn 2021. Prostate cancer cell extracellular vesicles increase mineralisation of bone osteoblast precursor cells in an in vitro model. Biology 10 (4) , 318. 10.3390/biology10040318 |
Dart, D A, Ashelford, K ORCID: https://orcid.org/0000-0003-3217-2811 and Jiang, W G ORCID: https://orcid.org/0000-0002-3283-1111 2020. AR mRNA Stability is increased with AR-antagonist resistance via 3' UTR variants. Endocrine Connections 9 (1) , pp. 9-19. 10.1530/EC-19-0340 |
Kandil, Sahar ORCID: https://orcid.org/0000-0003-1806-9623, Lee, Kok Yung, Davies, Laurie, Rizzo, Sebastiano A., Dart, D. Alwyn and Westwell, Andrew D. ORCID: https://orcid.org/0000-0002-5166-9236 2019. Discovery of deshydroxy bicalutamide derivatives as androgen receptor antagonists. European Journal of Medicinal Chemistry 167 , pp. 49-60. 10.1016/j.ejmech.2019.01.054 |
Dart, D 2019. Wnt-11 Expression promotes invasiveness and correlates with survival in human pancreatic ductal adeno carcinoma. Genes 10 , p. 921. 10.3390/genes10110921 |
Dart, D. Alwyn, Kandil, Sahar ORCID: https://orcid.org/0000-0003-1806-9623, Tommasini-Ghelfi, Serena, Almeida, Gilberto Serrano de, Bevan, Charlotte L., Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 and Westwell, Andrew D. ORCID: https://orcid.org/0000-0002-5166-9236 2018. Novel trifluoromethylated enobosarm analogues with potent antiandrogenic activity in vitro and tissue selectivity in vivo. Molecular Cancer Therapeutics 17 (9) , pp. 1846-1858. 10.1158/1535-7163.MCT-18-0037 |
Xie, Meng, Dart, Alwyn, Guo, Ting, Xing, Xiao-Fang, Cheng, Xiao-Jing, Du, Hong, Jiang, Wen G. ORCID: https://orcid.org/0000-0002-3283-1111, Wen, Xian-Zi and Ji, Jia-Fu 2018. MicroRNA-1 acts as a tumor suppressor microRNA by inhibiting angiogenesis-related growth factors in human gastric cancer. Gastric Cancer 21 (1) , pp. 41-54. 10.1007/s10120-017-0721-x |
Dart, Alwyn Dafydd, Uysal-Onganer, Pinar and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2017. Prostate-specific PTen deletion in mice activates inflammatory microRNA expression pathways in the epithelium early in hyperplasia development. Oncogenesis 6 (12) , 400. 10.1038/s41389-017-0007-5 |
Hu, T., Su, F., Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 and Dart, Dafydd Alwyn 2017. Overexpression of activin receptor-like kinase 7 in breast cancer cells is associated with decreased cell growth and adhesion. Anticancer Research 37 , pp. 3441-3451. 10.21873/anticanres.11712 |
Koushyar, Sarah, Economides, G, Zaat, Sharlene, Jiang, Wen ORCID: https://orcid.org/0000-0002-3283-1111, Bevan, Charlotte L. and Dart, Alwyn 2017. The prohibitin-repressive interaction with E2F1, is rapidly inhibited by androgen signalling in prostate cancer cells. Oncogenesis 6 , e3333. 10.1038/oncsis.2017.32 |
Owen, Sioned, Zhao, Huishan, Dart, Alwyn, Wang, Yamei, Ruge, Fiona, Gao, Yong, Wei, Cong, Wu, Yiling and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2016. Heat shock protein 27 is a potential indicator for response to YangZheng XiaoJi and chemotherapy agents in cancer cells. International Journal of Oncology 49 , pp. 1839-1847. 10.3892/ijo.2016.3685 |
Xie, Meng, Dart, Dafydd Alwyn, Owen, Sioned, Wen, Xianzi, Ji, Jiafu and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2016. Insights into roles of the miR-1, -133 and -206 family in gastric cancer (Review). Oncology Reports 36 (3) , pp. 1191-1198. 10.3892/or.2016.4908 |
Dart, Dafydd Alwyn and Bevan, Charlotte L. 2016. In vivo imaging of nuclear receptor transcriptional activity. McEwan, Iain J., ed. The Nuclear Receptor Superfamily, Vol. 1443. Methods in Molecular Biology, New York, NY: Humana Press, pp. 203-217. (10.1007/978-1-4939-3724-0_13) |
Koushyar, Sarah, Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 and Dart, Dafydd Alwyn 2015. Unveiling the potential of prohibitin in cancer. Cancer Letters 369 (2) , pp. 316-322. 10.1016/j.canlet.2015.09.012 |
Owen, S., Martin, Tracey Amanda ORCID: https://orcid.org/0000-0003-2690-4908, Dart, Dafydd Alwyn, Ablin, R. J., Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869 and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2015. The prostate Transglutaminase, TGase-4, is potentially linked to the junctional proteins at tight junctions of prostate tissues and prostate cancer cells [Abstract]. European Journal of Cancer 51 (S3) , S481. 10.1016/S0959-8049(15)30048-4 |
Owen, S., Dart, Dafydd Alwyn, Cui, Yuxin, Ablin, R., Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869 and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2015. Potential interactions between Interleukin-20 and Transglutaminase 4 might affect prostate cancer cell function [Abstract]. European Journal of Cancer 51 (S3) , S26-S27. 10.1016/S0959-8049(16)30088-0 |
Brooke, Greg N., Gamble, Simon C., Hough, Michael A., Begum, Shajna, Dart, Dafydd Alwyn, Odontiadis, Michael, Powell, Sue M., Fioretti, Flavia M., Bryan, Rosie A., Waxman, Jonathan, Wait, Robin and Bevan, Charlotte L. 2015. Antiandrogens act as selective androgen receptor modulators at the proteome level in prostate cancer cells. Molecular & Cellular Proteomics 14 (5) , pp. 1201-1216. 10.1074/mcp.M113.036764 |
Fletcher, Claire E., Dart, Dafydd and Bevan, Charlotte L. 2014. Interplay between steroid signalling and microRNAs: implications for hormone-dependent cancers. Endocrine-Related Cancer 21 (5) , R409-R429. 10.1530/ERC-14-0208 |
Dart, Dafydd Alwyn, Waxman, Jonathan, Aboagye, Eric O. and Bevan, Charlotte L. 2013. Visualising androgen receptor activity in male and female mice. PLoS ONE 8 (8) , e71694. 10.1371/journal.pone.0071694 |
Sita-Lumsden, A., Dart, Dafydd Alwyn, Waxman, J. and Bevan, C. L. 2013. Circulating microRNAs as potential new biomarkers for prostate cancer. British Journal of Cancer 108 (10) , pp. 1925-1930. 10.1038/bjc.2013.192 |
Sita-Lumsden, Ailsa, Fletcher, Claire E., Dart, Dafydd Alwyn, Brooke, Greg N., Waxman, Jonathan and Bevan, Charlotte L. 2013. Circulating nucleic acids as biomarkers of prostate cancer. Biomarkers in Medicine 7 (6) , pp. 867-877. 10.2217/bmm.13.104 |
Dart, Dafydd Alwyn, Brooke, G. N., Sita-Lumsden, A., Waxman, J. and Bevan, C. L. 2012. Reducing prohibitin increases histone acetylation, and promotes androgen independence in prostate tumours by increasing androgen receptor activation by adrenal androgens. Oncogene 31 (43) , pp. 4588-4598. 10.1038/onc.2011.591 |
Fletcher, Claire E., Dart, Dafydd Alwyn, Sita-Lumsden, Ailsa, Cheng, Helen, Rennie, Paul S. and Bevan, Charlotte L. 2012. Androgen-regulated processing of the oncomir MiR-27a, which targets Prohibitin in prostate cancer. Human Molecular Genetics 21 (14) , pp. 3112-3127. 10.1093/hmg/dds139 |
Brooke, Greg N., Culley, Rachel L., Dart, Dafydd Alwyn, Mann, David J., Gaughan, Luke, McCracken, Stuart R., Robson, Craig N., Spencer-Dene, Bradley, Gamble, Simon C., Powell, Sue M., Wait, Robin, Waxman, Jonathan, Walker, Marjorie M. and Bevan, Charlotte L. 2011. FUS/TLS is a novel mediator of androgen-dependent cell-cycle progression and prostate cancer growth. Cancer Research 71 (3) , pp. 914-924. 10.1158/0008-5472.CAN-10-0874 |
Dart, Dafydd Alwyn, Fletcher, C. L. and Bevan, C. 2010. Inhibiting androgen receptor activity in prostate cancer by cofactor manipulation [Abstract]. EJC Supplements 8 (5) , pp. 32-33. |
Dart, Dafydd Alwyn, Spencer-Dene, B., Gamble, S. C., Waxman, J. and Bevan, C. L. 2009. Manipulating prohibitin levels provides evidence for an in vivo role in androgen regulation of prostate tumours. Endocrine-Related Cancer 16 (4) , pp. 1157-1169. 10.1677/ERC-09-0028 |
Gamble, S. C., Chotai, D., Odontiadis, M., Dart, Dafydd Alwyn, Brooke, G. N., Powell, S. M., Reebye, V., Varela-Carver, A., Kawano, Y., Waxman, J. and Bevan, C. L. 2007. Prohibitin, a protein downregulated by androgens, represses androgen receptor activity. Oncogene 26 (12) , pp. 1757-1768. 10.1038/sj.onc.1209967 |
Powell, S. M., Brooke, G. N., Whitaker, H. C., Reebye, V., Gamble, S. C., Chotai, D., Dart, Dafydd Alwyn, Belandia, B. and Bevan, C. L. 2006. Mechanisms of androgen receptor repression in prostate cancer. Biochemical Society Transactions 34 (6) , pp. 1124-1127. 10.1042/BST0341124 |
Adams, K. E., Medhurst, A. L., Dart, Dafydd Alwyn and Lakin, N. D. 2006. Recruitment of ATR to sites of ionising radiation-induced DNA damage requires ATM and components of the MRN protein complex. Oncogene 25 (28) , pp. 3894-3904. 10.1038/sj.onc.1209426 |
Dart, Dafydd Alwyn, Adams, K. E., Akerman, I. and Lakin, N. D. 2004. Recruitment of the cell cycle checkpoint kinase ATR to chromatin during S-phase. Journal of Biological Chemistry 279 (16) , pp. 16433-16440. 10.1074/jbc.M314212200 |
Dart, Dafydd Alwyn, Picksley, Steven M., Cooper, Patricia A., Double, John A. and Bibby, Michael C. 2004. The role of p53 in the chemotherapeutic responses to cisplatin, doxorubicin and 5-fluorouracil treatment. International Journal of Oncology 24 (1) , pp. 115-125. |
Picksley, S. M., Dart, Dafydd Alwyn, Mansoor, M.S. and Loadman, P.M. 2001. Current advances in the inhibition of the auto-regulatory interaction between the p53 tumour suppressor protein and MDM2 protein. Expert Opinion on Therapeutic Patents 11 (12) , pp. 1825-1835. |