Browse by Current Cardiff authors

Kapustin, Alexander N., Tsakali, Sofia Serena, Whitehead, Meredith, Chennell, George, Wu, Meng-Ying, Molenaar, Chris, Kutikhin, Anton, Chen, Yimeng, Ahmad, Sadia, Bogdanov, Leo, Sinitsky, Maxim, Rubina, Kseniya, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Verweij, Frederik J., Pegtel, Dirk Michiel, Zingaro, Simona, Lobov, Arseniy, Zainullina, Bozhana, Owen, Dylan, Parsons, Maddy, Cheney, Richard E., Warren, Derek T., Humphries, Martin James, Iskratsch, Thomas, Holt, Mark and Shanahan, Catherine M. 2025. Matrix-associated extracellular vesicles modulate human smooth muscle cell adhesion and directionality by presenting collagen VI. eLife 12 , RP90375. 10.7554/elife.90375.3

Elfar, Miran Yousri, Brown, Helen Louise, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 and Stephens, Phil ORCID: https://orcid.org/0000-0002-0840-4996 2025. Antibiotic carry over is a confounding factor for cell-based antimicrobial research applications. Scientific Reports 15 (1) , 28310. 10.1038/s41598-025-14186-7

Durmaz, Esmahan, Esmaeli, Maryam, Lewis, Philip ORCID: https://orcid.org/0000-0002-3353-0708, Cimaglia, Gloria, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 and Mead, Benjamin ORCID: https://orcid.org/0000-0001-5855-0097 2025. R-28 cell-derived extracellular vesicles protect retinal ganglion cells in glaucoma. Neural Regeneration Research 10 , 4103. 10.4103/NRR.NRR-D-24-00709

Zhang, Xiaoyan, Dumčius, Povilas, Mikhaylov, Roman, Qi, Jiangfa, Stringer, Mercedes, Sun, Chao, Nguyen, Van Dien, Zhou, You ORCID: https://orcid.org/0000-0002-1743-1291, Sun, Xianfang ORCID: https://orcid.org/0000-0002-6114-0766, Liang, Dongfang, Liu, Dongge, Yan, Bing, Feng, Xi, Mei, Changjun, Xu, Cong, Feng, Mingqian, Fu, Yongqing, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Zhi, Ruicong, Tian, Liangfei, Dong, Zhiqiang and Yang, Xin ORCID: https://orcid.org/0000-0002-8429-7598 2024. Surface acoustic wave‐enhanced multi‐view acoustofluidic rotation cytometry (MARC) for pre‐cytopathological screening. Advanced Science 11 (39) , 2403574. 10.1002/advs.202403574

Bordanaba-Florit, Guillermo, Royo, Felix, Alboniga, Oihane E., Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Falcon-Perez, Juan Manuel and Webber, Jason ORCID: https://orcid.org/0000-0003-4772-3014 2024. Integration of proteomic and metabolomic analysis reveal distinct metabolic alterations of prostate cancer-associated fibroblasts compared to normal fibroblasts from patient's stroma samples. BBA - Molecular Basis of Disease 1870 (6) , 167229. 10.1016/j.bbadis.2024.167229

Hyland, Mairead, Mennan, Claire, Davies, Rebecca, Wilson, Emma, Tonge, Daniel P., Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 and Kehoe, Oksana 2023. Extracellular vesicles derived from umbilical cord mesenchymal stromal cells show enhanced anti-inflammatory properties via upregulation of miRNAs after pro-inflammatory priming. Stem Cell Reviews and Reports 19 , pp. 2391-2406. 10.1007/s12015-023-10586-2

Dumcius, Povilas, Mikhaylov, Roman, Zhang, Xiaoyan, Bareford, Matthew, Stringer, Mercedes, Errington, Rachel ORCID: https://orcid.org/0000-0002-8016-4376, Sun, Chao, Gonzalez, Esperanza, Krukovski, Tomas, Falcon-Perez, Juan M., Liang, Dongfang, Fu, Yong-Qing, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 and Yang, Xin ORCID: https://orcid.org/0000-0002-8429-7598 2023. Dual-wave acoustofluidic centrifuge for ultrafast concentration of nanoparticles and extracellular vesicles (small 35/2023). Small 19 (35) , 2370274. 10.1002/smll.202370274

Dumcius, Povilas, Mikhaylov, Roman, Zhang, Xiaoyan, Bareford, Matthew, Stringer Martin, Mercedes, Errington, Rachel ORCID: https://orcid.org/0000-0002-8016-4376, Sun, Chao, Gonzalez, Esperanza, Krukovski, Tomaš, Falcon-Perez, Juan M, Liang, Dongfang, Fu, Yong-Qing, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 and Yang, Xin ORCID: https://orcid.org/0000-0002-8429-7598 2023. Dual-Wave Acoustofluidic Centrifuge for Ultrafast Concentration of Nanoparticles and Extracellular Vesicles. Small 19 (35) , 2300390. 10.1002/smll.202300390

Wang, Hanlin, Boardman, Joe, Zhang, Xiaoyan, Sun, Chao, Cai, Meng, Wei, Jun, Dong, Zhiqiang, Feng, Mingqian, Liang, Dongfang, Hu, Sheng, Qian, Yu, Dong, Shuang, Fu, Yongqing, Torun, Hamdi, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Wu, Zhenlin, Xie, Zhihua ORCID: https://orcid.org/0000-0002-5180-8427 and Yang, Xin ORCID: https://orcid.org/0000-0002-8429-7598 2023. An enhanced tilted-angle acoustic tweezer for mechanical phenotyping of cancer cells. Analytica Chimica Acta 1255 , 341120. 10.1016/j.aca.2023.341120

Owen, Jasmine S., Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 and Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843 2022. Cancer-associated fibroblast heterogeneity, activation and function: implications for prostate cancer. Biomolecules 13 (1) , 67. 10.3390/biom13010067

Knight, Rob ORCID: https://orcid.org/0000-0001-9927-6354, Board-Davies, Emma, Brown, Helen, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Davis, Terence ORCID: https://orcid.org/0000-0003-2780-0262, Karatas, Ben, Burston, James, Tabi, Zsuzsanna, Falcon-Perez, Juan M, Paisey, Stephen ORCID: https://orcid.org/0000-0002-2274-3708 and Stephens, Phil ORCID: https://orcid.org/0000-0002-0840-4996 2022. Oral progenitor cell line-derived small extracellular vesicles as a treatment for preferential wound healing outcome. Stem Cells Translational Medicine 11 (8) , pp. 861-875. 10.1093/stcltm/szac037

van Niel, Guillaume, Carter, David R. F., Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Lambert, Daniel W., Raposo, Graça and Vader, Pieter 2022. Challenges and directions in studying cell-cell communication by extracellular vesicles. Nature Reviews Molecular Cell Biology 23 , 369–382. 10.1038/s41580-022-00460-3

Brown, Sarah V., Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 and Waddington, Rachel J. ORCID: https://orcid.org/0000-0001-5878-1434 2022. Identifying the efficacy of extracellular vesicles in osteogenic differentiation: an EV-Lution in regenerative medicine. Frontiers in Dental Medicine 3 , 849724. 10.3389/fdmed.2022.849724

Brown, Helen, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 and Stephens, Phil ORCID: https://orcid.org/0000-0002-0840-4996 2021. The role of bacterial extracellular vesicles in chronic wound infections: current knowledge and future challenges. Wound Repair and Regeneration 29 (6) , pp. 864-880. 10.1111/wrr.12949

Mikhaylov, Roman, Stringer Martin, Mercedes, Dumcius, Povilas, Wang, Hanlin, Wu, Fangda, Zhang, Xiaoyan, Alghamdi, Fahad, Akhimien, Victory, Sun, Chao, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Fu, Yong Qing (Richard), Ye, Lin ORCID: https://orcid.org/0000-0002-0303-2409, Dong, Zhiqiang and Yang, Xin ORCID: https://orcid.org/0000-0002-8429-7598 2021. A reconfigurable and portable acoustofluidic system based on flexible printed circuit board for the manipulation of microspheres. Journal of Micromechanics and Microengineering 31 (7) , 074003. 10.1088/1361-6439/ac0515

Erdbrügger, Uta, Blijdorp, Charles J., Bijnsdorp, Irene V., Borràs, Francesc E., Burger, Dylan, Bussolati, Benedetta, Byrd, James Brian, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Dear, James W., Falcón-Pérez, Juan M., Grange, Cristina, Hill, Andrew F., Holthöfer, Harry, Hoorn, Ewout J., Jenster, Guido, Jimenez, Connie R., Junker, Kerstin, Klein, John, Knepper, Mark A., Koritzinsky, Erik H., Luther, James M., Lenassi, Metka, Leivo, Janne, Mertens, Inge, Musante, Luca, Oeyen, Eline, Puhka, Maija, Royen, Martin E., Sánchez, Catherine, Soekmadji, Carolina, Thongboonkerd, Visith, Steijn, Volkert, Verhaegh, Gerald, Webber, Jason P., Witwer, Kenneth, Yuen, Peter S.T., Zheng, Lei, Llorente, Alicia and Martens-Uzunova, Elena S. 2021. Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles. Journal of Extracellular Vesicles 10 (7) , e12093. 10.1002/jev2.12093

Lanning, Ben, Webber, Jason ORCID: https://orcid.org/0000-0003-4772-3014, Uysal-Ongane, Pinar, Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 and Dart, Dafydd Alwyn 2021. Prostate cancer cell extracellular vesicles increase mineralisation of bone osteoblast precursor cells in an in vitro model. Biology 10 (4) , 318. 10.3390/biology10040318

Wu, Fangda, Shen, Ming Hong, Yang, Jian, Wang, Hanlin, Mikhaylov, Roman, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Qin, Xinghua, Sun, Chao, Xie, Zhihua ORCID: https://orcid.org/0000-0002-5180-8427, Cai, Meng, Wei, Jun, Liang, Dongfang, Yuan, Fan, Wu, Zhenlin, Fu, Yongqing, Yang, Zhiyong, Sun, Xianfang ORCID: https://orcid.org/0000-0002-6114-0766, Tian, Liangfei and Yang, Xin 2021. An enhanced tilted-angle acoustofluidic chip for cancer cell manipulation. IEEE Electron Device Letters 42 (4) , pp. 577-580. 10.1109/LED.2021.3062292

Evans, Lauren, Milward, Kate ORCID: https://orcid.org/0000-0003-3019-4443, Attanoos, Richard, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Errington, Rachel ORCID: https://orcid.org/0000-0002-8016-4376 and Tabi, Zsuzsanna 2021. Macrophage plasticity and function in the lung tumour microenvironment revealed in 3D heterotypic spheroid and explant models. Biomedicines 9 (3) , 302. 10.3390/biomedicines9030302

Sun, Chao, Wu, Fangda, Wallis, David J. ORCID: https://orcid.org/0000-0002-0475-7583, Shen, Ming Hong ORCID: https://orcid.org/0000-0002-3891-7231, Yuan, Fan, Yang, Jian ORCID: https://orcid.org/0000-0002-8429-7598, Wu, Jianzhong, Xie, Zhihua ORCID: https://orcid.org/0000-0002-5180-8427, Liang, Dongfang, Wang, Hanlin, Tickle, Rowan, Mikhaylov, Roman, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Zhou, You ORCID: https://orcid.org/0000-0002-1743-1291, Wu, Zhenlin, Fu, Yongqing, Xun, Wenpeng and Yang, Xin ORCID: https://orcid.org/0000-0002-8429-7598 2020. Gallium nitride: a versatile compound semiconductor as novel piezoelectric film for acoustic tweezer in manipulation of cancer cells. IEEE Transactions on Electron Devices 67 (8) , pp. 3355-3361. 10.1109/TED.2020.3002498

Mikhaylov, Roman, Wu, Fangda, Wang, Hanlin, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Sun, Chao, Xie, Zhihua ORCID: https://orcid.org/0000-0002-5180-8427, Liang, Dongfang, Dong, Yinhua, Yuan, Fan, Moschou, Despina, Wu, Zhenlin, Shen, Minghong, Yang, Jian ORCID: https://orcid.org/0000-0002-8429-7598, Fu, Yong Qing, Yang, Zhiyong ORCID: https://orcid.org/0000-0002-8429-7598, Burton, Christian, Errington, Rachel ORCID: https://orcid.org/0000-0002-8016-4376, Wiltshire, Marie and Yang, Xin ORCID: https://orcid.org/0000-0002-8429-7598 2020. Development and characterisation of acoustofluidic devices using detachable electrodes made from PCB. Lab on a Chip 20 (10) , pp. 1807-1814. 10.1039/C9LC01192G

Bliss, Carly M., Parsons, Andrea J., Nachbagauer, Raffael, Hamilton, Jennifer R., Cappuccini, Federica, Ulaszewska, Marta, Webber, Jason P. ORCID: https://orcid.org/0000-0003-4772-3014, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Hill, Adrian V.S. and Coughlan, Lynda 2020. Targeting antigen to the surface of EVs improves the in vivo immunogenicity of human and non-human adenoviral vaccines in mice. Molecular Therapy - Methods and Clinical Development 16 , pp. 108-125. 10.1016/j.omtm.2019.12.003

Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Boilard, Eric, Buzas, Edit I, Cheng, Lesley, Falcón-Perez, Juan Manual, Gardiner, Chris, Gustafson, Dakota, Gualerzi, Alice, Hendrix, An, Hoffman, Andrew, Jones, Jennifer, Lässer, Cecilia, Lawson, Charlotte, Lenassi, Metka, Nazarenko, Irina, O?Driscoll, Lorraine, Pink, Ryan, Siljander, Pia R-M, Soekmadji, Carolina, Wauben, Marca, Welsh, Joshua A, Witwer, Ken, Zheng, Lei and Nieuwland, Rienk 2019. Considerations towards a roadmap for collection, handling and storage of blood extracellular vesicles. Journal of Extracellular Vesicles 8 (1) , 1647027. 10.1080/20013078.2019.1647027

Brook, Amy C., Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Kift-Morgan, Ann, Raby, Anne-Catherine ORCID: https://orcid.org/0000-0002-5354-5835, Shephard, Alex P., Mariotti, Barbara, Cuff, Simone M. ORCID: https://orcid.org/0000-0002-0546-3579, Bazzoni, Flavia, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342 and Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348 2019. Neutrophil-derived miR-223 as local biomarker of bacterial peritonitis. Scientific Reports 9 , 10136. 10.1038/s41598-019-46585-y

Spaull, Robert, McPherson, Bryony, Gialeli, Andriana, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Uney, James, Heep, Axel and Cordero-Llana, Óscar 2019. Exosomes populate the cerebrospinal fluid of preterm infants with post-haemorrhagic hydrocephalus. International Journal of Developmental Neuroscience 73 , pp. 59-65. 10.1016/j.ijdevneu.2019.01.004

Seed, Robert I., Taurozzi, Alberto J., Wilcock, Daniel J., Nappo, Giovanna, Erb, Holger H. H., Read, Martin L., Gurney, Mark ORCID: https://orcid.org/0000-0003-1119-6638, Archer, Leanne K., Ito, Saburo, Rumsby, Martin G., Petrie, John L., Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Maitland, Norman J. and Collins, Anne T. 2019. The putative tumour suppressor protein Latexin is secreted by prostate luminal cells and is downregulated in malignancy. Scientific Reports 9 (1) , 5120. 10.1038/s41598-019-41379-8

Faruqu, Farid N., Tzu-Wen Wang, Julie, Xu, Lizhou, McNickle, Luke, Ming-Yiu Chong, Eden, Walters, Adam, Gurney, Mark ORCID: https://orcid.org/0000-0003-1119-6638, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Smyth, Lesley A., Hider, Robert, Sosabowski, Jane and Al-Jamal, Khuloud T. 2019. Membrane radiolabelling of exosomes for comparative biodistribution analysis in immunocompetent and immunodeficient mice – a novel and universal approach. Theranostics 9 (6) , pp. 1666-1682. 10.7150/thno.27891

Théry, Clotilde, Witwer, Kenneth W, Aikawa, Elena, Alcaraz, Maria Jose, Anderson, Johnathon D, Andriantsitohaina, Ramaroson, Antoniou, Anna, Arab, Tanina, Archer, Fabienne, Atkin-Smith, Georgia K, Ayre, D Craig, Bach, Jean-Marie, Bachurski, Daniel, Baharvand, Hossein, Balaj, Leonora, Baldacchino, Shawn, Bauer, Natalie N, Baxter, Amy A, Bebawy, Mary, Beckham, Carla, Bedina Zavec, Apolonija, Benmoussa, Abderrahim, Berardi, Anna C, Bergese, Paolo, Bielska, Ewa, Blenkiron, Cherie, Bobis-Wozowicz, Sylwia, Boilard, Eric, Boireau, Wilfrid, Bongiovanni, Antonella, Borràs, Francesc E, Bosch, Steffi, Boulanger, Chantal M, Breakefield, Xandra, Breglio, Andrew M, Brennan, Meadhbh Á, Brigstock, David R, Brisson, Alain, Broekman, Marike LD, Bromberg, Jacqueline F, Bryl-Górecka, Paulina, Buch, Shilpa, Buck, Amy H, Burger, Dylan, Busatto, Sara, Buschmann, Dominik, Bussolati, Benedetta, Buzás, Edit I, Byrd, James Bryan, Camussi, Giovanni, Carter, David RF, Caruso, Sarah, Chamley, Lawrence W, Chang, Yu-Ting, Chaudhuri, Amrita Datta, Chen, Chihchen, Chen, Shuai, Cheng, Lesley, Chin, Andrew R, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Clerici, Stefano P, Cocks, Alex, Cocucci, Emanuele, Coffey, Robert J, Cordeiro-da-Silva, Anabela, Couch, Yvonne, Coumans, Frank AW, Coyle, Beth, Crescitelli, Rossella, Criado, Miria Ferreira, D?Souza-Schorey, Crislyn, Das, Saumya, de Candia, Paola, De Santana, Eliezer F, De Wever, Olivier, del Portillo, Hernando A, Demaret, Tanguy, Deville, Sarah, Devitt, Andrew, Dhondt, Bert, Di Vizio, Dolores, Dieterich, Lothar C, Dolo, Vincenza, Dominguez Rubio, Ana Paula, Dominici, Massimo, Dourado, Mauricio R, Driedonks, Tom AP, Duarte, Filipe V, Duncan, Heather M, Eichenberger, Ramon M, Ekström, Karin, EL Andaloussi, Samir, Elie-Caille, Celine, Erdbrügger, Uta, Falcón-Pérez, Juan M, Fatima, Farah, Fish, Jason E, Flores-Bellver, Miguel, Försönits, András, Frelet-Barrand, Annie, Fricke, Fabia, Fuhrmann, Gregor, Gabrielsson, Susanne, Gámez-Valero, Ana, Gardiner, Chris, Gärtner, Kathrin, Gaudin, Raphael, Gho, Yong Song, Giebel, Bernd, Gilbert, Caroline, Gimona, Mario, Giusti, Ilaria, Goberdhan, Deborah CI, Görgens, André, Gorski, Sharon M, Greening, David W, Gross, Julia Christina, Gualerzi, Alice, Gupta, Gopal N, Gustafson, Dakota, Handberg, Aase, Haraszti, Reka A, Harrison, Paul, Hegyesi, Hargita, Hendrix, An, Hill, Andrew F, Hochberg, Fred H, Hoffmann, Karl F, Holder, Beth, Holthofer, Harry, Hosseinkhani, Baharak, Hu, Guoku, Huang, Yiyao, Huber, Veronica, Hunt, Stuart, Ibrahim, Ahmed Gamal-Eldin, Ikezu, Tsuneya, Inal, Jameel M, Isin, Mustafa, Ivanova, Alena, Jackson, Hannah K, Jacobsen, Soren, Jay, Steven M, Jayachandran, Muthuvel, Jenster, Guido, Jiang, Lanzhou, Johnson, Suzanne M, Jones, Jennifer C, Jong, Ambrose, Jovanovic-Talisman, Tijana, Jung, Stephanie, Kalluri, Raghu, Kano, Shin-ichi, Kaur, Sukhbir, Kawamura, Yumi, Keller, Evan T, Khamari, Delaram, Khomyakova, Elena, Khvorova, Anastasia, Kierulf, Peter, Kim, Kwang Pyo, Kislinger, Thomas, Klingeborn, Mikael, Klinke, David J, Kornek, Miroslaw, Kosanovi?, Maja M, Kovács, Árpád Ferenc, Krämer-Albers, Eva-Maria, Krasemann, Susanne, Krause, Mirja, Kurochkin, Igor V, Kusuma, Gina D, Kuypers, Sören, Laitinen, Saara, Langevin, Scott M, Languino, Lucia R, Lannigan, Joanne, Lässer, Cecilia, Laurent, Louise C, Lavieu, Gregory, Lázaro-Ibáñez, Elisa, Le Lay, Soazig, Lee, Myung-Shin, Lee, Yi Xin Fiona, Lemos, Debora S, Lenassi, Metka, Leszczynska, Aleksandra, Li, Isaac TS, Liao, Ke, Libregts, Sten F, Ligeti, Erzsebet, Lim, Rebecca, Lim, Sai Kiang, Lin?, Aija, Linnemannstöns, Karen, Llorente, Alicia, Lombard, Catherine A, Lorenowicz, Magdalena J, Lörincz, Ákos M, Lötvall, Jan, Lovett, Jason, Lowry, Michelle C, Loyer, Xavier, Lu, Quan, Lukomska, Barbara, Lunavat, Taral R, Maas, Sybren LN, Malhi, Harmeet, Marcilla, Antonio, Mariani, Jacopo, Mariscal, Javier, Martens-Uzunova, Elena S, Martin-Jaular, Lorena, Martinez, M Carmen, Martins, Vilma Regina, Mathieu, Mathilde, Mathivanan, Suresh, Maugeri, Marco, McGinnis, Lynda K, McVey, Mark J, Meckes, David G, Meehan, Katie L, Mertens, Inge, Minciacchi, Valentina R, Möller, Andreas, Møller Jørgensen, Malene, Morales-Kastresana, Aizea, Morhayim, Jess, Mullier, François, Muraca, Maurizio, Musante, Luca, Mussack, Veronika, Muth, Dillon C, Myburgh, Kathryn H, Najrana, Tanbir, Nawaz, Muhammad, Nazarenko, Irina, Nejsum, Peter, Neri, Christian, Neri, Tommaso, Nieuwland, Rienk, Nimrichter, Leonardo, Nolan, John P, Nolte-?t Hoen, Esther NM, Hooten, Nicole Noren, O?Driscoll, Lorraine, O?Grady, Tina, O?Loghlen, Ana, Ochiya, Takahiro, Olivier, Martin, Ortiz, Alberto, Ortiz, Luis A, Osteikoetxea, Xabier, Ostegaard, Ole, Ostrowski, Matias, Park, Jaesung, Pegtel, D. Michiel, Peinado, Hector, Perut, Francesca, Pfaffl, Michael W, Phinney, Donald G, Pieters, Bartijn CH, Pink, Ryan C, Pisetsky, David S, Pogge von Strandmann, Elke, Polakovicova, Iva, Poon, Ivan KH, Powell, Bonita H, Prada, Ilaria, Pulliam, Lynn, Quesenberry, Peter, Radeghieri, Annalisa, Raffai, Robert L, Raimondo, Stefania, Rak, Janusz, Ramirez, Marcel I, Raposo, Graça, Rayyan, Morsi S, Regev-Rudzki, Neta, Ricklefs, Franz L, Robbins, Paul D, Roberts, David D, Rodrigues, Silvia C, Rohde, Eva, Rome, Sophie, Rouschop, Kasper MA, Rughetti, Aurelia, Russell, Ashley E, Saá, Paula, Sahoo, Susmita, Salas-Huenuleo, Edison, Sánchez, Catherine, Saugstad, Julie A, Saul, Meike J, Schiffelers, Raymond M, Schneider, Raphael, Schøyen, Tine Hiorth, Scott, Aaron, Shahaj, Eriomina, Sharma, Shivani, Shatnyeva, Olga, Shekari, Faezeh, Shelke, Ganesh Vilas, Shetty, Ashok K, Shiba, Kiyotaka, Siljander, Pia R-M, Silva, Andreia M, Skowronek, Agata, Snyder, Orman L, Soares, Rodrigo Pedro, Sódar, Barbara W, Soekmadji, Carolina, Sotillo, Javier, Stahl, Philip D, Stoorvogel, Willem, Stott, Shannon L, Strasser, Erwin F, Swift, Simon, Tahara, Hidetoshi, Tewari, Muneesh, Timms, Kate, Tiwari, Swasti, Tixeira, Rochelle, Tkach, Mercedes, Toh, Wei Seong, Tomasini, Richard, Torrecilhas, Ana Claudia, Tosar, Juan Pablo, Toxavidis, Vasilis, Urbanelli, Lorena, Vader, Pieter, van Balkom, Bas WM, van der Grein, Susanne G, Van Deun, Jan, van Herwijnen, Martijn JC, Van Keuren-Jensen, Kendall, van Niel, Guillaume, van Royen, Martin E, van Wijnen, Andre J, Vasconcelos, M Helena, Vechetti, Ivan J, Veit, Tiago D, Vella, Laura J, Velot, Émilie, Verweij, Frederik J, Vestad, Beate, Viñas, Jose L, Visnovitz, Tamás, Vukman, Krisztina V, Wahlgren, Jessica, Watson, Dionysios C, Wauben, Marca HM, Weaver, Alissa, Webber, Jason P ORCID: https://orcid.org/0000-0003-4772-3014, Weber, Viktoria, Wehman, Ann M, Weiss, Daniel J, Welsh, Joshua A, Wendt, Sebastian, Wheelock, Asa M, Wiener, Zoltán, Witte, Leonie, Wolfram, Joy, Xagorari, Angeliki, Xander, Patricia, Xu, Jing, Yan, Xiaomei, Yáñez-Mó, María, Yin, Hang, Yuana, Yuana, Zappulli, Valentina, Zarubova, Jana, ??kas, Vytautas, Zhang, Jian-ye, Zhao, Zezhou, Zheng, Lei, Zheutlin, Alexander R, Zickler, Antje M, Zimmermann, Pascale, Zivkovic, Angela M, Zocco, Davide and Zuba-Surma, Ewa K 2018. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. Journal of Extracellular Vesicles 7 (1) , 1535750. 10.1080/20013078.2018.1535750

Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Buschmann, Dominik, Byrd, J. Brian, Carter, David R. F., Cheng, Lesley, Compton, Carolyn, Daaboul, George, Devitt, Andrew, Falcon-Perez, Juan Manuel, Gardiner, Chris, Gustafson, Dakota, Harrison, Paul, Helmbrecht, Clemens, Hendrix, An, Hill, Andrew, Hoffman, Andrew, Jones, Jennifer C., Kalluri, Raghu, Kang, Ji Yoon, Kirchner, Benedikt, Lässer, Cecilia, Lawson, Charlotte, Lenassi, Metka, Levin, Carina, Llorente, Alicia, Martens-Uzunova, Elena S., Möller, Andreas, Musante, Luca, Ochiya, Takahiro, Pink, Ryan C, Tahara, Hidetoshi, Wauben, Marca H. M., Webber, Jason P. ORCID: https://orcid.org/0000-0003-4772-3014, Welsh, Joshua A., Witwer, Kenneth W., Yin, Hang and Nieuwland, Rienk 2018. Summary of the ISEV workshop on extracellular vesicles as disease biomarkers, held in Birmingham, UK, during December 2017. Journal of Extracellular Vesicles 7 (1) , 1473707. 10.1080/20013078.2018.1473707

Yeung, V., Webber, J. P. ORCID: https://orcid.org/0000-0003-4772-3014, Dunlop, E. A. ORCID: https://orcid.org/0000-0002-9209-7561, Morgan, H., Hutton, J., Gurney, M. ORCID: https://orcid.org/0000-0003-1119-6638, Jones, E., Falcon-Perez, J., Tabi, Z., Errington, R. ORCID: https://orcid.org/0000-0002-8016-4376 and Clayton, A. ORCID: https://orcid.org/0000-0002-3087-9226 2018. Rab35-dependent extracellular nanovesicles are required for induction of tumour supporting stroma. Nanoscale 10 (18) , pp. 8547-8559. 10.1039/C8NR02417K

Slatter, David A., Percy, Charles L., Allen-Redpath, Keith, Gajsiewicz, Joshua M., Brooks, Nick J., Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Tyrrell, Victoria J., Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Lauder, Sarah N., Watson, Andrew, Dul, Maria ORCID: https://orcid.org/0000-0002-0192-2280, Garcia-Diaz, Yoel, Aldrovandi, Maceler, Heurich, Meike, Hall, Judith ORCID: https://orcid.org/0000-0002-6770-7372, Morrissey, James H., Lacroix-Desmazes, Sebastien, Delignat, Sandrine, Jenkins, P. Vincent, Collins, Peter W. ORCID: https://orcid.org/0000-0002-6410-1324 and O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 2018. Enzymatically oxidized phospholipids restore thrombin generation in coagulation factor deficiencies. JCI Insight 3 (6) , e98459. 10.1172/jci.insight.98459

Carter, David Raul Francisco, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Devitt, Andrew, Hunt, Stuart and Lambert, Daniel W 2018. Extracellular vesicles in the tumour microenvironment. Philosophical Transactions B: Biological Sciences 373 (1737) , 20160475. 10.1098/rstb.2016.0475

Martinez, Vanesa G., O'Neill, Sadhbh, Salimu, Josephine, Breslin, Susan, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Crown, John and O'Driscoll, Lorraine 2017. Resistance to HER2-targeted anti-cancer drugs is associated with immune evasion in cancer cells and their derived extracellular vesicles. OncoImmunology 6 (12) , e1362530. 10.1080/2162402X.2017.1362530

Griffiths, Steven, Cormier, Michelle, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 and Doucette, Alan 2017. Differential proteome analysis of extracellular vesicles from breast cancer cell lines by chaperone affinity enrichment. Proteomes 5 (4) , 25. 10.3390/proteomes5040025

Roberts-Dalton, H. D. ORCID: https://orcid.org/0000-0003-4331-6067, Cocks, A., Falcon-Perez, J. M., Sayers, E. J. ORCID: https://orcid.org/0000-0002-2621-1119, Webber, J. P. ORCID: https://orcid.org/0000-0003-4772-3014, Watson, P. ORCID: https://orcid.org/0000-0003-0250-7852, Clayton, A. ORCID: https://orcid.org/0000-0002-3087-9226 and Jones, A. T. ORCID: https://orcid.org/0000-0003-2781-8905 2017. Fluorescence labelling of extracellular vesicles using a novel thiol-based strategy for quantitative analysis of cellular delivery and intracellular traffic. Nanoscale 9 (36) , pp. 13693-13706. 10.1039/C7NR04128D

Welton, Joanne L., Loveless, Samantha ORCID: https://orcid.org/0000-0002-5124-4115, Stone, Timothy, Von Ruhland, Christopher, Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909 and Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 2017. Cerebrospinal fluid extracellular vesicle enrichment for protein biomarker discovery in neurological disease; multiple sclerosis. Journal of Extracellular Vesicles 6 (1) , 1369805. 10.1080/20013078.2017.1369805

Pathan, M., Keerthikumar, S., Chisanga, D., Alessandro, R., Ang, C.-S., Askenase, P., Batagov, A. O., Benito-Martin, A., Camussi, G., Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Collino, F., Di Vizio, D., Falcon-Perez, J. M., Fonseca, P., Fonseka, P., Fontana, S., Gho, Y. S., Hendrix, A., Nolte-'t Hoen, E., Iraci, N., Kastaniegaard, K., Kislinger, T., Kowal, J., Kurochkin, I. V., Leonardi, T., Liang, Y., Llorente, A., Lunavat, T. R., Maji, S., Monteleone, F., Overbye, A., Panaretakis, T., Patel, T., Peinado, H., Pluchino, S., Principe, S., Ronquist, G., Royo, F., Sahoo, S., Spinelli, C., Stensballe, A., Thery, C., Van Herwijnen, M. J., Wauben, M., Welton, J., Zhao, K. and Mathivanan, S. 2017. A novel community driven software for functional enrichment analysis of extracellular vesicles data. Journal of Extracellular Vesicles 6 , 1321455. 10.1080/20013078.2017.1321455

Salimu, Josephine, Webber, Jason ORCID: https://orcid.org/0000-0003-4772-3014, Gurney, Mark ORCID: https://orcid.org/0000-0003-1119-6638, Al-Taei, Saly, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 and Tabi, Zsuzsanna 2017. Dominant immunosuppression of dendritic cell function by prostate-cancer-derived exosomes. Journal of Extracellular Vesicles 6 (1) , 1368823. 10.1080/20013078.2017.1368823

Al-Taei, Saly, Salimu, Josephine, Spary, Lisa Kate, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Lester, Jason F. and Tabi, Zsuzsanna 2016. Prostaglandin E2-mediated adenosinergic effects on CD14+ cells: self-amplifying immunosuppression in cancer. OncoImmunology 6 (2) , pp. 312-318. 10.1080/2162402X.2016.1268308

Welton, Joanne Louise, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Gurney, Mark ORCID: https://orcid.org/0000-0003-1119-6638, Webber, Jason Paul ORCID: https://orcid.org/0000-0003-4772-3014, Spary, Lisa Kate, Gil Carton, David, Falcón-Pérez, Juan Manuel, Walton, Sean Peter, Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869, Tabi, Zsuzsanna and Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 2016. Proteomics analysis of vesicles isolated from plasma and urine of prostate cancer patients using a multiplex, aptamer-based protein array. Journal of Extracellular Vesicles 5 , 31209. 10.3402/jev.v5.31209

Emanueli, Costanza, Shearn, Andrew I. U., Laftah, Abas, Fiorentino, Francesca, Reeves, Barnaby C., Beltrami, Cristina, Mumford, Andrew, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Gurney, Mark ORCID: https://orcid.org/0000-0003-1119-6638, Shantikumar, Saran and Angelini, Gianni D. 2016. Coronary artery-bypass-graft surgery increases the plasma concentration of exosomes carrying a cargo of cardiac microRNAs: an example of exosome trafficking out of the human heart with potential for cardiac biomarker discovery. PLoS ONE 11 (4) , e0154274. 10.1371/journal.pone.0154274

Webber, Jason P. ORCID: https://orcid.org/0000-0003-4772-3014, Spary, Lisa Kate, Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869, Tabi, Zsuzsanna, Brewis, Ian Andrew and Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 2016. Prostate stromal cell proteomics analysis discriminates normal from tumour reactive stromal phenotypes. Oncotarget 7 , pp. 20124-20139. 10.18632/oncotarget.7716

Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Lawson, Charlotte, Gardiner, Chris, Harrison, Paul and Carter, David 2016. The 2nd United Kingdom Extracellular Vesicle Forum Meeting Abstracts. Journal of Extracellular Vesicles 5 (1) , 30924. 10.3402/jev.v5.30924

Connolly, Katherine D., Guschina, Irina A., Yeung, Vincent, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Shazli Draman, Mohd, Von Ruhland, Christopher, Ludgate, Marian Elizabeth, James, Philip E. and Rees, Dafydd Aled ORCID: https://orcid.org/0000-0002-1165-9092 2015. Characterisation of adipocyte-derived extracellular vesicles released pre- and post-adipogenesis. Journal of Extracellular Vesicles 4 (s1) , 29159. 10.3402/jev.v4.29159

Beltrami, Cristina, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Newbury, Lucy, Corish, Peter, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2015. Stabilization of urinary microRNAs by association with exosomes and argonaute 2 protein. Non-Coding RNA 1 (2) , pp. 151-166. 10.3390/ncrna1020151

Salimu, Josephine, Spary, Lisa K., Al-Taei, Saly, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Mason, Malcolm D. ORCID: https://orcid.org/0000-0003-1505-2869, Staffurth, John ORCID: https://orcid.org/0000-0002-7834-3172 and Tabi, Zsuzsanna 2015. Cross-Presentation of the Oncofetal Tumor Antigen 5T4 from Irradiated Prostate Cancer Cells—A Key Role for Heat-Shock Protein 70 and Receptor CD91. Cancer Immunology Research 3 (6) , pp. 678-688. 10.1158/2326-6066.CIR-14-0079

Webber, Jason P. ORCID: https://orcid.org/0000-0003-4772-3014, Yeung, Vincent and Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 2015. Extracellular vesicles as modulators of the cancer microenvironment. Seminars in Cell and Developmental Biology 40 , pp. 27-34. 10.1016/j.semcdb.2015.01.013

Welton, Joanne Louise, Webber, Jason P. ORCID: https://orcid.org/0000-0003-4772-3014, Botos, Laur-Alexandru, Jones, Michael and Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 2015. Ready-made chromatography columns for extracellular vesicle isolation from plasma. Journal of Extracellular Vesicles 4 , 27269. 10.3402/jev.v4.27269

Kim, D.-K., Lee, J., Kim, S. R., Choi, D.-S., Yoon, Y. J., Kim, J. H., Go, G., Nhung, D., Hong, K., Jang, S. C., Kim, S.-H., Park, K.-S., Kim, O. Y., Park, H. T., Seo, J. H., Aikawa, E., Baj-Krzyworzeka, M., van Balkom, B. W. M., Belting, M., Blanc, L., Bond, V., Bongiovanni, A., Borras, F. E., Buee, L., Buzas, E. I., Cheng, L., Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Cocucci, E., Dela Cruz, C. S., Desiderio, D. M., Di Vizio, D., Ekstrom, K., Falcon-Perez, J. M., Gardiner, C., Giebel, B., Greening, D. W., Gross, J. C., Gupta, D., Hendrix, A., Hill, A. F., Hill, M. M., Nolte-'t Hoen, E., Hwang, D. W., Inal, J., Jagannadham, M. V., Jayachandran, M., Jee, Y.-K., Jorgensen, M., Kim, K. P., Kim, Y.-K., Kislinger, T., Lasser, C., Lee, D. S., Lee, H., van Leeuwen, J., Lener, T., Liu, M.-L., Lotvall, J., Marcilla, A., Mathivanan, S., Moller, A., Morhayim, J., Mullier, F., Nazarenko, I., Nieuwland, R., Nunes, D. N., Pang, K., Park, J., Patel, T., Pocsfalvi, G., del Portillo, H., Putz, U., Ramirez, M. I., Rodrigues, M. L., Roh, T.-Y., Royo, F., Sahoo, S., Schiffelers, R., Sharma, S., Siljander, P., Simpson, R. J., Soekmadji, C., Stahl, P., Stensballe, A., St pie, E., Tahara, H., Trummer, A., Valadi, H., Vella, L. J., Wai, S. N., Witwer, K., Yanez-Mo, M., Youn, H., Zeidler, R. and Gho, Y. S. 2015. EVpedia: a community web portal for extracellular vesicles research. Bioinformatics 31 (6) , pp. 933-939. 10.1093/bioinformatics/btu741

Chowdhury, Ridwana, Webber, Jason P. ORCID: https://orcid.org/0000-0003-4772-3014, Gurney, Mark ORCID: https://orcid.org/0000-0003-1119-6638, Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869, Tabi, Zsuzsanna and Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 2015. Cancer exosomes trigger mesenchymal stem cell differentiation into pro-angiogenic and pro-invasive myofibroblasts. Oncotarget 6 (2) , pp. 715-731. 10.18632/oncotarget.2711

Webber, J. P. ORCID: https://orcid.org/0000-0003-4772-3014, Spary, L. K., Sanders, A. J. ORCID: https://orcid.org/0000-0002-7997-5286, Chowdhury, R., Jiang, W. G. ORCID: https://orcid.org/0000-0002-3283-1111, Steadman, R. ORCID: https://orcid.org/0000-0002-1303-2496, Wymant, J., Jones, A. T. ORCID: https://orcid.org/0000-0003-2781-8905, Kynaston, H. ORCID: https://orcid.org/0000-0003-1902-9930, Mason, M. D. ORCID: https://orcid.org/0000-0003-1505-2869, Tabi, Z. and Clayton, A. ORCID: https://orcid.org/0000-0002-3087-9226 2015. Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes. Oncogene 34 (3) , pp. 290-302. 10.1038/onc.2013.560

Willis, G. R., Connolly, K. ORCID: https://orcid.org/0000-0003-1074-1710, Ladell, K. ORCID: https://orcid.org/0000-0002-9856-2938, Davies, T. S., Guschina, I. A., Ramji, D. ORCID: https://orcid.org/0000-0002-6419-5578, Miners, K., Price, D. A. ORCID: https://orcid.org/0000-0001-9416-2737, Clayton, A. ORCID: https://orcid.org/0000-0002-3087-9226, James, P. E. and Rees, D. A. ORCID: https://orcid.org/0000-0002-1165-9092 2014. Young women with polycystic ovary syndrome have raised levels of circulating annexin V-positive platelet microparticles. Human Reproduction 29 (12) , pp. 2756-2763. 10.1093/humrep/deu281

Galluzzi, L., Vacchelli, E., Bravo-San Pedro, J. M., Buqué, A., Senovilla, L., Baracco, E. E., Bloy, N., Castoldi, F., Abastado, J. P., Agostinis, P., Aranda, F., Apte, R. N., Ayyoub, M., Beckhove, P., Blay, J. Y., Bracci, L., Caignard, A., Castelli, C., Cavallo, F., Celis, E., Cerundolo, F., Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Colombo, M. P., Coussens, L., Dhodapkar, M. V., Eggermont, A. M., Fearon, D. T., Fridman, W. H., Fučíková, J., Gabrilovich, D., Galon, J., Garg, A., Ghiringhelli, F., Giaccone, G., Gilboa, E., Gnjatic, S., Hoos, A., Hosmalin, A., Jäger, D., Kalinski, P., Kärre, K., Kepp, O., Kiessling, R., Kirkwood, J. M., Klein, E., Knuth, A., Lewis, C. E., Liblau, R., Lotze, M. T., Lugli, E., Mach, J. P., Mattei, F., Mavilio, D., Melero, I., Melief, C. J., Mittendorf, E. A., Moretta, L., Odunsi, A., Okada, H., Palucka, A. K., Peter, M. E., Pienta, K. J., Porgador, A., Prendergast, G. C., Rabinovich, G. A., Restifo, N. P., Rizvi, N., Sautès-Fridman, C., Schreiber, H., Seliger, B., Shiku, H., Silva-Santos, B., Smyth, M. J., Speiser, D. E., Spisek, R., Srivastava, P. K., Talmadge, J. E., Tartour, E., Van Der Burg, S. E., Van Den Eynde, B. J., Vile, R., Wagner, H, Webster, J. S., Whiteside, T. L., Wolchok, J. D., Zitvogel, L., Zou, W. and Kroemer, G. 2014. Classification of current anticancer immunotherapies. Oncotargets and Therapy 5 (24) , pp. 12472-12508. 10.18632/oncotarget.2998

Spary, Lisa Kate, Salimu, Josephine, Webber, Jason P. ORCID: https://orcid.org/0000-0003-4772-3014, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Mason, Malcolm david ORCID: https://orcid.org/0000-0003-1505-2869 and Tabi, Zsuzsanna 2014. Tumor stroma-derived factors skew monocyte to dendritic cell differentiation toward a suppressive CD14+PD-L1+phenotype in prostate cancer. OncoImmunology 3 (9) , e955331. 10.4161/21624011.2014.955331

Spary, Lisa Kate, Al-Taei, Saly, Salimu, Josephine, Cook, Alexander, Ager, Ann, Watson, Heulwen Angharad, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Staffurth, John Nicholas ORCID: https://orcid.org/0000-0002-7834-3172, Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869 and Tabi, Zsuzsanna 2014. Enhancement of T cell responses as a result of synergy between lower doses of radiation and T cell stimulation. The Journal of Immunology 192 (7) , pp. 3101-3110. 10.4049/jimmunol.1302736

Webber, Jason ORCID: https://orcid.org/0000-0003-4772-3014, Stone, Timothy C., Katilius, Evaldas, Smith, Breanna C., Gordon, Bridget, Mason, Malcolm D. ORCID: https://orcid.org/0000-0003-1505-2869, Tabi, Zsuzsanna, Brewis, Ian A. and Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 2014. Proteomics analysis of cancer exosomes using a novel modified aptamer-based array (SOMAscanTM) platform. Molecular and Cellular Proteomics 13 (4) , pp. 1050-1064. 10.1074/mcp.M113.032136

Brennan, Samuel E., Nham, Tran, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, McGowan, Eileen M., Cozzi, Paul J. and Martiniello-Wilks, Rosetta 2013. Prostate cancer exosomes offering novel circulating biomarkers for early cancer diagnosis and prognosis [Abstract]. The Journal of Gene Medicine 15 (8-9) , pp. 331-332. 10.1002/jgm.2740

Midgley, Adam Christopher, Rogers, Mathew James, Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 2013. Transforming growth factor-β1 (TGF-β1)-stimulated fibroblast to myofibroblast differentiation Is mediated by hyaluronan (HA)-facilitated epidermal growth factor receptor (EGFR) and CD44 co-localization in lipid rafts. Journal of Biological Chemistry 288 (21) , pp. 14824-14838. 10.1074/jbc.M113.451336

Webber, Jason P. ORCID: https://orcid.org/0000-0003-4772-3014 and Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 2013. How pure are your vesicles? Journal of Extracellular Vesicles 2 , 19861. 10.3402/jev.v2i0.19861

Kalra, Hina, Simpson, Richard J., Ji, Hong, Aikawa, Elena, Altevogt, Peter, Askenase, Philip, Bond, Vincent C., Borràs, Francesc E., Breakefield, Xandra, Budnik, Vivian, Buzas, Edit, Camussi, Giovanni, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Cocucci, Emanuele, Falcon-Perez, Juan M., Gabrielsson, Susanne, Gho, Yong Song, Gupta, Dwijendra, Harsha, H. C., Hendrix, An, Hill, Andrew F., Inal, Jameel M., Jenster, Guido, Krämer-Albers, Eva-Maria, Lim, Sai Kiang, Llorente, Alicia, Lötvall, Jan, Marcilla, Antonio, Mincheva-Nilsson, Lucia, Nazarenko, Irina, Nieuwland, Rienk, Nolte-'t Hoen, Esther N. M., Pandey, Akhilesh, Patel, Tushar, Piper, Melissa G., Pluchino, Stefano, Prasad, T. S. Keshava, Rajendran, Lawrence, Raposo, Graca, Record, Michel, Reid, Gavin E., Sánchez-Madrid, Francisco, Schiffelers, Raymond M., Siljander, Pia, Stensballe, Allan, Stoorvogel, Willem, Taylor, Douglas, Thery, Clotilde, Valadi, Hadi, van Balkom, Bas W. M., Vázquez, Jesús, Vidal, Michel, Wauben, Marca H. M., Yáñez-Mó, María, Zoeller, Margot and Mathivanan, Suresh 2012. Vesiclepedia: A compendium for extracellular vesicles with continuous community annotation. PLoS Biology 10 (12) , e1001450. 10.1371/journal.pbio.1001450

Shah, Kunal M., Webber, Jason P. ORCID: https://orcid.org/0000-0003-4772-3014, Carzaniga, Raffaella, Taylor, Deborah M., Fusi, Luca, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Brosens, Jan J., Hartshorne, Geraldine and Christian, Mark 2012. Induction of microRNA resistance and secretion in differentiating human endometrial stromal cells [Letter]. Journal of Molecular Cell Biology 5 (1) , pp. 67-70. 10.1093/jmcb/mjs058

Beltrami, Cristina, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2012. Analysis of urinary microRNAs in chronic kidney disease. Biochemical Society Transactions 40 (4) , pp. 875-879. 10.1042/BST20120090

Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 2012. Cancer cells use exosomes as tools to manipulate immunity and the microenvironment. OncoImmunology 1 (1) , pp. 78-80. 10.4161/onci.1.1.17826

Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Al-Taei, Saly, Webber, Jason P. ORCID: https://orcid.org/0000-0003-4772-3014, Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869 and Tabi, Zsuzsanna 2011. Cancer exosomes express CD39 and CD73, which suppress T cells through adenosine production. The Journal of Immunology 187 (2) , pp. 676-683. 10.4049/jimmunol.1003884

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Tabi, Zsuzsanna, Spary, Lisa Kate, Coleman, Sharon Louise, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869 and Staffurth, John Nicholas ORCID: https://orcid.org/0000-0002-7834-3172 2010. Resistance of CD45RA- T cells to apoptosis and functional impairment, and activation of tumor-antigen specific T cells during radiation therapy of prostate cancer. The Journal of Immunology 185 (2) , pp. 1330-1339. 10.4049/jimmunol.1000488

Welton, Joanne L., Khanna, Sanjay, Giles, Peter James ORCID: https://orcid.org/0000-0003-3143-6854, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Brewis, Ian Andrew, Staffurth, John Nicholas ORCID: https://orcid.org/0000-0002-7834-3172, Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869 and Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 2010. Proteomics analysis of bladder cancer exosomes. Molecular & Cellular Proteomics 9 (6) , pp. 1324-1338. 10.1074/mcp.M000063-MCP201

Mitchell, Philip J., Welton, Joanne L., Staffurth, John Nicholas ORCID: https://orcid.org/0000-0002-7834-3172, Court, Jacquelyn, Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869, Tabi, Zsuzsanna and Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 2009. Can urinary exosomes act as treatment response markers in prostate cancer? Journal Of Translational Medicine 7 (4) , n/a. 10.1186/1479-5876-7-4

Navabi, Hossein, Jasani, Bharat, Reece, Ann, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Tabi, Zsuzsanna, Donninger, C., Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869 and Adams, Malcolm 2009. A clinical grade poly I:C-analogue (Ampligen®) promotes optimal DC maturation and Th1-type T cell responses of healthy donors and cancer patients in vitro. Vaccine 27 (1) , pp. 107-115. 10.1016/j.vaccine.2008.10.024

Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 and Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869 2009. Exosomes in tumour immunity. Current Oncology -Toronto- 16 (3) , pp. 46-49.

Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Mitchell, John Paul, Court, Jacquelyn, Linnane, Seamus, Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869 and Tabi, Zsuzsanna 2008. Human tumor-derived exosomes down-modulate NKG2D expression. Journal of Immunology 180 (11) , pp. 7249-7258.

Mitchell, John Paul, Court, Jacqueline, Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869, Tabi, Zsuzsanna and Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 2008. Increased exosome production from tumour cell cultures using the Integra CELLine Culture System. Journal of Immunological Methods 335 (1-2) , pp. 98-105. 10.1016/j.jim.2008.03.001

Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869, Mitchell, John Paul and Tabi, Zsuzsanna 2007. Human tumour-derived exosomes selectively impair lymphocyte responses to Interleukin-2. Cancer Research 67 , pp. 7458-7466. 10.1158/0008-5472.CAN-06-3456

Théry, Clotilde, Amigorena, Sebastian, Raposo, Graça and Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 2006. Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Current Protocols in Cell Biology , Unit 322. 10.1002/0471143030.cb0322s30

Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Turkes, Atilla, Mason, M. D. ORCID: https://orcid.org/0000-0003-1505-2869 and Tabi, Zsuzsanna 2005. Induction of heat shock proteins in B-cell exosomes. Journal of Cell Science 118 (16) , pp. 3631-3638. 10.1242/jcs.02494

Coleman, Sharon Louise, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869, Jasani, Bharat, Adams, Malcolm and Tabi, Zsuzsanna 2005. Recovery of CD8+ T-cell function during systemic chemotherapy in advanced ovarian cancer. Cancer Research 65 (15) , pp. 7000-7006. 10.1158/0008-5472.CAN-04-3792

Coleman, Sharon Louise, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869, Jasani, Bharat, Adams, Malcolm and Tabi, Zsuzsanna 2005. Recovery of CD8+ T-cell function during systemic chemotherapy in advanced ovarian cancer. Cancer Research 65 (15) , pp. 7000-6. 10.1158/0008-5472.CAN-04-3792

Adams, M., Navabi, H., Croston, D., Coleman, Sharon Louise, Tabi, Zsuzsanna, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Jasani, Bharat and Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869 2005. The rationale for combined chemo/immunotherapy using a Toll-like receptor 3 (TLR3) agonist and tumour-derived exosomes in advanced ovarian cancer. Vaccine 23 (17-18) , pp. 2374-2378. 10.1016/j.vaccine.2005.01.014

Navabi, H., Croston, D., Hobot, Jan, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Zitvogel, L., Jasani, Bharat, Bailey-Wood, R., Wilson, Keith, Tabi, Zsuzsanna, Mason, Malcolm ORCID: https://orcid.org/0000-0003-1505-2869 and Adams, M. 2005. Preparation of human ovarian cancer ascites-derived exosomes for a clinical trial. Blood Cells, Molecules, and Diseases 35 (2) , pp. 149-152. 10.1016/j.bcmd.2005.06.008

Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 and Tabi, Zsuzsanna 2005. Exosomes and the MICA-NKG2D system in cancer. Blood Cells, Molecules, and Diseases 34 (3) , pp. 206-213. 10.1016/j.bcmd.2005.03.003

Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Turkes, Atilla, Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496, Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869 and Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X 2004. Adhesion and signaling by B cell-derived exosomes: the role of integrins. The FASEB Journal 18 , pp. 977-979. 10.1096/fj.03-1094fje

Thomas, Gareth John, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Thomas, Janet, Davies, Malcolm and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 2003. Structural and functional changes in heparan sulfate proteoglycan expression associated with the myofibroblastic phenotype. America Journal of Pathology 162 (3) , pp. 977-989.

Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Harris, Claire Louise, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869 2003. Antigen-presenting cell exosomes are protected from complement-mediated lysis by expression of CD55 and CD59. European Journal of Immunology 33 (2) , pp. 522-31. 10.1002/immu.200310028

Blaber, Robert, Stylianou, Eleni, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 2003. Selective regulation of ICAM-1 and RANTES gene expression after ICAM-1 ligation on human renal fibroblasts. Journal of the American Society of Nephrology 14 (1) , pp. 116-127. 10.1097/01.ASN.0000040595.35207.62

Savage, Philip, Cowburn, Pam, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Man, Stephen Tzekwung ORCID: https://orcid.org/0000-0001-9103-1686, Lawson, Thomas, Ogg, Graham, Lemoine, Nick, McMichael, Andrew and Epenetos, Agamemnon 2002. Anti-viral cytotoxic T cells inhibit the growth of cancer cells with antibody targeted hla class I/peptide complexes in scid mice. International Journal of Cancer 98 (4) , pp. 561-566. 10.1002/ijc.10219

Savage, Philip, Cowburn, Pam, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Man, Stephen Tzekwung ORCID: https://orcid.org/0000-0001-9103-1686, McMichael, Andrew, Lemoine, Nick, Epenetos, Agamemnon and Ogg, Graham 2002. Induction of viral and tumour specific CTL responses using antibody targeted HLA class I peptide complexes. British Journal of Cancer 86 (8) , pp. 1336-1342. 10.1038/sj.bjc.6600223

Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Thomas, Janet, Thomas, Gareth J., Davies, Malcolm and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 2001. Cell surface heparan sulfate proteoglycans control the response of renal interstitial fibroblasts to fibroblast growth factor-2. Kidney International 59 (6) , pp. 2084-2094. 10.1046/j.1523-1755.2001.00723.x

Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Court, Jacquelyn, Navabi, Hossein, Adams, Malcolm, Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869, Hobot, Jan Adam, Newman, Geoff R. and Jasani, Bharat 2001. Analysis of antigen presenting cell derived exosomes, based on immuno-magnetic isolation and flow cytometry. Journal of Immunological Methods 247 (1-2) , pp. 163-174. 10.1016/S0022-1759(00)00321-5

Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 1999. ICAM-1 interactions in the renal interstitium: a novel activator of fibroblasts during nephritis. Histology and Histopathology 14 (3) , pp. 861-870.

Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Thomas, Janet, Thomas, Gareth, Davies, Malcolm and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 1999. Fibroblasts from the cortical interstitium express cell surface heparan sulphate proteoglycans [Abstract]. Kidney International 55 (6) , p. 2588. 10.1046/j.1523-1755.2002.t01-1-00456.x

Evans, R. E., Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Martin, J., Williams, J. D., Davies, M. and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 1999. Neutrophil binding stimulates the synthesis, release and activation of MMP 3 and MMP 2 from endothelial cells in vitro [Abstract]. Kidney International 55 (5) , p. 2105. 10.1046/j.1523-1755.1999.00404.x

Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Evans, Rachel A., Pettit, Elizabeth, Hallett, Maurice, Williams, John David and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 1998. Cellular activation through the ligation of intercellular adhesion molecule-1. Journal of Cell Science 111 (4) , pp. 443-453.

Evans, R. A., Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Martin, J., Williams, J. D., Davies, M. and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 1997. Neutrophil binding stimulates the synthesis, release and activation of MMP 2 from endothelial cells in vitro. Journal of the American Society of Nephrology 8 , A2390-A2390.

Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Williams, J. D. and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 1997. The ligation of ICAM-1 on renal cortical fibroblasts initiates the de novo expression of ICAM-1 and VCAM-1. Journal of the American Society of Nephrology 8 , A2385-A2385.

Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Williams, J. D. and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 1997. Ligation of ICAM-1 on the surface of renal cortical fibroblasts stimulates de novo expression of ICAM-1 and VCAM-1 [Abstract]. Kidney International 52 (1) , pp. 262-263. 10.1038/ki.1997.329

Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 and Williams, John David 1997. Cells isolated from the human cortical interstitium resemble myofibroblasts and bind neutrophils in an ICAM-1--dependent manner. Journal of the American Society of Nephrology 8 (4) , pp. 604-615.

Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Pettit, J., Hallett, B. and Williams, J. D. 1996. Leukocytes trigger an influx of calcium in renal interstitial fibroblasts through ligation ICAM-1. Journal of the American Society of Nephrology 7 (9) , A2594-A2594.

Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 and Williams, J. D. 1995. Human renal cortical fibroblasts (RCF) bind leukocytes in-vitro through a CD18-dependent and VLA(4)-dependent interaction. Journal of the American Society of Nephrology 6 (3) , p. 894.