Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2025.
The physiopathology of brain-derived neurotrophic factor.
Physiological Reviews
105
(4)
, pp. 2073-2140.
10.1152/physrev.00038.2024
|
|
|
Akutsu, Fumie, Sugino, Shiro, Watanabe, Mitsuo, Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X and Kojima, Masaaki
2025.
A highly sensitive enzyme‑linked immunosorbent assay allows accurate measurements of brain‑derived neurotrophic factor levels in human saliva.
F1000Research
14
, 161.
10.12688/f1000research.160304.2
|
|
|
Ateaque, Sarah, Merkouris, Spyros and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2023.
Neurotrophin signalling in the human nervous system.
Frontiers in Molecular Neuroscience
16
, 1225373.
10.3389/fnmol.2023.1225373
|
|
|
Want, Andrew, Nan, Xinsheng ORCID: https://orcid.org/0000-0002-0865-7934, Kokkali, Eirini, Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X and Morgan, James E ORCID: https://orcid.org/0000-0002-8920-1065
2023.
Brain-derived neurotrophic factor released from blood platelets prevents dendritic atrophy of lesioned adult central nervous system neurons.
Brain Communications
5
(2)
, pp. 1-14.
10.1093/braincomms/fcad046
|
|
|
Ateaque, Sarah, Merkouris, Spyros, Wyatt, Sean ORCID: https://orcid.org/0000-0002-0572-234X, Allen, Nicholas D. ORCID: https://orcid.org/0000-0003-4009-186X, Xie, Jia, DiStefano, Peter S., Lindsay, Ronald M. and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2022.
Selective activation and down-regulation of Trk receptors by neurotrophins in human neurons co-expressing TrkB and TrkC.
Journal of Neurochemistry
161
(6)
, pp. 463-477.
10.1111/jnc.15617
|
|
|
Ateaque, Sarah and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2021.
A new molecular target for antidepressants.
Cell Research
31
, pp. 489-490.
10.1038/s41422-021-00500-1
|
|
Dingsdale, Hayley ORCID: https://orcid.org/0000-0002-2919-8722, Nan, Xinsheng ORCID: https://orcid.org/0000-0002-0865-7934, Garay, Samantha M., Mueller, Annett, Sumption, Lorna A. ORCID: https://orcid.org/0000-0002-2259-9128, Chacon Fernandez, Pedro, Martinez Garay, Isabel ORCID: https://orcid.org/0000-0001-6849-7496, Ghevaert, Cedric, Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X and John, Rosalind M. ORCID: https://orcid.org/0000-0002-3827-7617
2021.
The placenta protects the fetal circulation from anxiety-driven elevations in maternal serum levels of brain-derived neurotrophic factor.
Translational Psychiatry
11
(1)
, 62.
10.1038/s41398-020-01176-8
|
|
|
Naegelin, Yvonne, Kuhle, Jens, Schädelin, Sabine, Datta, Alexandre N., Magon, Stefano, Amann, Michael, Barro, Christian, Ramelli, Gian Paolo, Heesom, Kate, Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X, Weber, Peter and Kappos, Ludwig
2021.
Fingolimod in children with Rett syndrome: the FINGORETT study.
Orphanet Journal of Rare Diseases
16
(1)
, 19.
10.1186/s13023-020-01655-7
|
|
|
Naegelin, Yvonne, Saeuberli, Katharina, Schaedelin, Sabine, Dingsdale, Hayley ORCID: https://orcid.org/0000-0002-2919-8722, Magon, Stefano, Baranzini, Sergio, Amann, Michael, Parmar, Katrin, Tsagkas, Charidimos, Calabrese, Pasquale, Penner, Iris Katharina, Kappos, Ludwig and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2020.
Levels of brain-derived neurotrophic factor in patients with multiple sclerosis.
Annals of Clinical and Translational Neurology
7
(11)
, pp. 2251-2261.
10.1002/acn3.51215
|
|
|
Wosnitzka, Erin, Nan, Xinsheng ORCID: https://orcid.org/0000-0002-0865-7934, Nan, Jeff, Chacón-Fernández, Pedro, Kussmaul, Lothar, Schuler, Michael, Hengerer, Bastian and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2020.
A new mouse line reporting the translation of brain-derived neurotrophic factor using green fluorescent protein.
eNeuro
7
(1)
, ENEURO.0462-19.2019.
10.1523/ENEURO.0462-19.2019
|
|
|
Merkouris, Spyros, Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X, Binley, Kate E., Allen, Nicholas D. ORCID: https://orcid.org/0000-0003-4009-186X, Stepanov, Alexey V., Wu, Nicholas C., Grande, Geramie, Lin, Chih-Wei, Li, Meng ORCID: https://orcid.org/0000-0002-4803-4643, Nan, Xinsheng ORCID: https://orcid.org/0000-0002-0865-7934, Chacon-Fernandez, Pedro, DiStefano, Peter S., Lindsay, Ronald M., Lerner, Richard A. and Xie, Jia
2018.
Fully human agonist antibodies to TrkB using autocrine cell-based selection from a combinatorial antibody library.
Proceedings of the National Academy of Sciences
115
(30)
, E7023-E7032.
10.1073/pnas.1806660115
|
|
|
Naegelin, Yvonne, Dingsdale, Hayley ORCID: https://orcid.org/0000-0002-2919-8722, Saeuberli, Katharina, Schädelin, Sabine, Kappos, Ludwig and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2018.
Measuring and validating the levels of brain-derived neurotrophic factor in human serum.
eNeuro
5
(2)
, e0419-17.2018.
10.1523/ENEURO.0419-17.2018
|
|
|
Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X and Cassels, Laura ORCID: https://orcid.org/0000-0002-1214-7179
2017.
Scaling pain threshold with microRNAs.
Science
356
(6343)
, pp. 1124-1125.
10.1126/science.aan6784
|
|
|
Binley, Kate E., Ng, Wai S., Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X, Song, Bing ORCID: https://orcid.org/0000-0001-9356-2333 and Morgan, James E. ORCID: https://orcid.org/0000-0002-8920-1065
2016.
Brain-derived neurotrophic factor prevents dendritic retraction of adult mouse retinal ganglion cells.
European Journal of Neuroscience
44
(3)
, pp. 2028-2039.
10.1111/ejn.13295
|
|
|
Chacon-Fernandez, Pedro, Sauberli, Katharina, Colzani, Maria, Moreau, Thomas, Ghevaert, Cedric and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2016.
Brain-derived neurotrophic factor in megakaryocytes.
Journal of Biological Chemistry
291
(19)
, pp. 9872-9881.
10.1074/jbc.M116.720029
|
|
|
Sirko, Swetlana, Irmler, Martin, Gascón, Sergio, Bek, Sarah, Schneider, Sarah, Dimou, Leda, Obermann, Jara, De Souza Paiva, Daisylea, Poirier, Francoise, Beckers, Johannes, Hauck, Stefanie M., Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X and Götz, Magdalena
2015.
Astrocyte reactivity after brain injury-: The role of galectins 1 and 3.
Glia
63
(12)
, pp. 2340-2361.
10.1002/glia.22898
|
|
|
Dekkers, Martijn p. J., Nikoletopoulou, Vassiliki and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2013.
Death of developing neurons: New insights and implications for connectivity.
Journal of Cell Biology
203
(3)
, pp. 385-393.
10.1083/jcb.201306136
|
|
|
Dekkers, M. P. J. and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2013.
Programmed cell death in neuronal development.
Science
340
(6128)
, pp. 39-41.
10.1126/science.1236152
|
|
Yazdani, Morteza, Deogracias, Rubén, Guy, Jacky, Poot, Raymond A., Bird, Adrian and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2012.
Disease modeling using embryonic stem cells: MeCP2 regulates nuclear size and RNA synthesis in neurons.
Stem Cells
30
(10)
, pp. 2128-2139.
10.1002/stem.1180
|
|
Deogracias, Rubén, Yazdani, Morteza, Dekkers, Martijn P. J., Guy, Jacky, Ionescu, Mihai Constantin S., Vogt, Kaspar E. and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2012.
Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome.
Proceedings of the National Academy of Sciences of the United States of America
109
(35)
, pp. 14230-14235.
10.1073/pnas.1206093109
|
|
Tiwari, Vijay K., Burger, Lukas, Nikoletopoulou, Vassiliki, Deogracias, Ruben, Thakurela, Sudhir, Wirbelauer, Christiane, Kaut, Johannes, Terranova, Remi, Hoerner, Leslie, Mielke, Christian, Boege, Fritz, Murr, Rabih, Peters, Antoine H. F. M., Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X and Schubeler, Dirk
2012.
Target genes of Topoisomerase IIβ regulate neuronal survival and are defined by their chromatin state.
Proceedings of the National Academy of Sciences of the United States of America
109
(16)
, E934-E943.
10.1073/pnas.1119798109
|
|
Dieni, Sandra, Matsumoto, Tomoya, Dekkers, Martijn, Rauskolb, Stefanie, Ionescu, Mihai S., Deogracias, Ruben, Gundelfinger, Eckart D., Kojima, Masami, Nestel, Sigrun, Frotscher, Michael and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2012.
BDNF and its pro-peptide are stored in presynaptic dense core vesicles in brain neurons.
Journal of Cell Biology
196
(6)
, pp. 775-788.
10.1083/jcb.201201038
|
|
|
Bischoff, V., Deogracias, R., Poirier, F. and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2012.
Seizure-induced neuronal death is suppressed in the absence of the endogenous lectin galectin-1.
Journal of Neuroscience
32
(44)
, pp. 15590-15600.
10.1523/JNEUROSCI.4983-11.2012
|
|
|
Bischoff, Vincent, Nikoletopoulou, Vassiliki and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2011.
Sauver ou tuer.
Médecine Sciences M/S
27
(2)
, pp. 119-121.
10.1051/medsci/2011272119
|
|
Nikoletopoulou, Vassiliki, Lickert, Heiko, Frade, José Maria, Rencurel, Chantal, Giallonardo, Patrizia, Zhang, Lixin, Bibel, Miriam and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2010.
Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not.
Nature
467
(7311)
, pp. 59-63.
10.1038/nature09336
|
|
Rauskolb, S., Zagrebelsky, M., Dreznjak, A., Deogracias, R., Matsumoto, T., Wiese, S., Erne, B., Sendtner, M., Schaeren-Wiemers, N., Korte, M. and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2010.
Global deprivation of brain-derived neurotrophic factor in the CNS reveals an area-specific requirement for dendritic growth.
Journal of Neuroscience
30
(5)
, pp. 1739-1749.
10.1523/JNEUROSCI.5100-09.2010
|
|
|
Pasutto, Francesca, Matsumoto, Tomoya, Mardin, Christian Y., Sticht, Heinrich, Brandstätter, Johann H., Michels-Rautenstrauss, Karin, Weisschuh, Nicole, Gramer, Eugen, Ramdas, Wishal D., van Koolwijk, Leonieke M.E., Klaver, Caroline C.W., Vingerling, Johannes R., Weber, Bernhard H.F., Kruse, Friedrich E., Rautenstrauss, Bernd, Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X and Reis, André
2009.
Heterozygous NTF4 mutations impairing neurotrophin-4 signaling in patients with primary open-angle glaucoma.
American Journal of Human Genetics
85
(4)
, pp. 447-456.
10.1016/j.ajhg.2009.08.016
|
|
Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2009.
Caution urged in trial of stem cells to treat spinal-cord injury [Letter].
Nature
458
(7234)
, p. 29.
10.1038/458029a
|
|
Schrenk-Siemens, Katrin, Perez-Alcala, Siro, Richter, Jens, Lacroix, Emmanuel, Rahuel, Joseph, Korte, Martin, Müller, Ulrike, Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X and Bibel, Miriam
2008.
Embryonic stem cell-derived neurons as a cellular system to study gene function: lack of amyloid precursor proteins APP and APLP2 leads to defective synaptic transmission.
Stem Cells
26
(8)
, pp. 2153-2163.
10.1634/stemcells.2008-0010
|
|
Matsumoto, Tomoya, Rauskolb, Stefanie, Polack, Martin, Klose, Johannes, Kolbeck, Roland, Korte, Martin and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2008.
Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF.
Nature Neuroscience
11
(2)
, pp. 131-133.
10.1038/nn2038
|
|
Nicholson, J. R., Peter, J. -C., Lecourt, A. -C., Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X and Hofbauer, Karl G.
2007.
Melanocortin-4 receptor activation stimulates hypothalamic brain-derived neurotrophic factor release to regulate food intake, body temperature and cardiovascular function.
Journal of Neuroendocrinology
19
(12)
, pp. 974-982.
10.1111/j.1365-2826.2007.01610.x
|
|
Affolter, Markus and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2007.
Self-renewal in the fly kidney.
Developmental Cell
13
(3)
, pp. 321-322.
10.1016/j.devcel.2007.08.002
|
|
Plachta, Nicolas, Annaheim, Christine, Bissière, Stephanie, Lin, Shuo, Rüegg, Markus, Hoving, Sjouke, Müller, Dieter, Poirier, Françoise, Bibel, Miriam and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2007.
Identification of a lectin causing the degeneration of neuronal processes using engineered embryonic stem cells.
Nature Neuroscience
10
(6)
, pp. 712-719.
10.1038/nn1897
|
|
Bibel, Miriam, Richter, Jens, Lacroix, Emmanuel and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2007.
Generation of a defined and uniform population of CNS progenitors and neurons from mouse embryonic stem cells.
Nature Protocols
2
(5)
, pp. 1034-1043.
10.1038/nprot.2007.147
|
|
Zagrebelsky, M., Holz, A., Dechant, G., Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X, Bonhoeffer, T. and Korte, M.
2005.
The p75 neurotrophin receptor negatively modulates dendrite complexity and spine density in hippocampal neurons.
Journal of Neuroscience
25
(43)
, pp. 9989-9999.
10.1523/JNEUROSCI.2492-05.2005
|
|
Rosch, H., Schweigreiter, R., Bonhoeffer, T., Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X and Korte, M.
2005.
The neurotrophin receptor p75NTR modulates long-term depression and regulates the expression of AMPA receptor subunits in the hippocampus.
Proceedings of the National Academy of Sciences of the United States of America
102
(20)
, pp. 7362-7367.
10.1073/pnas.0502460102
|
|
Götz, Magdalena and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2005.
Radial glial cells: defined and major intermediates between embryonic stem cells and CNS neurons.
Neuron
46
(3)
, pp. 369-372.
10.1016/j.neuron.2005.04.012
|
|
Plachta, Nicholas, Bibel, Miriam, Tucker, Kerry Lee and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2004.
Developmental potential of defined neural progenitors derived from mouse embryonic stem cells.
Development
131
(21)
, pp. 5449-5456.
10.1242/dev.01420
|
|
Bibel, Miriam, Richter, Jens, Schrenk, Katrin, Tucker, Kerry Lee, Staiger, Volker, Korte, Martin, Goetz, Magdalena and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2004.
Differentiation of mouse embryonic stem cells into a defined neuronal lineage.
Nature Neuroscience
7
(9)
, pp. 1003-1009.
10.1038/nn1301
|
|
Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2004.
Death of injured neurons caused by the precursor of nerve growth factor.
Proceedings of the National Academy of Sciences of the United States of America
101
(16)
, pp. 5703-5704.
10.1073/pnas.0401374101
|
|
Andorfer, Cathy, Kress, Yvonne, Espinoza, Marisol, De Silva, Rohan, Tucker, Kerry L., Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X, Duff, Karen and Davies, Peter
2003.
Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms.
Journal of Neurochemistry
86
(3)
, pp. 582-590.
10.1046/j.1471-4159.2003.01879.x
|
|
Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2002.
Neurobiology: Neurotrophin channels excitement.
Nature
419
(6908)
, pp. 683-684.
10.1038/419683a
|
|
Heins, Nico, Malatesta, Paolo, Cecconi, Francesco, Nakafuku, Masato, Tucker, Kerry Lee, Hack, Michael A., Chapouton, Prisca, Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X and Götz, Magdalena
2002.
Glial cells generate neurons: the role of the transcription factor Pax6.
Nature Neuroscience
5
(4)
, pp. 308-315.
10.1038/nn828
|
|
Wernig, Marius, Tucker, Kerry Lee, Gornik, Volker, Schneiders, Angelika, Buschwald, Rachel, Wiestler, Otmar D., Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X and Bristle, Oliver
2002.
Tau EGFP embryonic stem cells: an efficient tool for neuronal lineage selection and transplantation.
Journal of Neuroscience Research
69
(6)
, pp. 918-924.
10.1002/jnr.10395
|
|
Dechant, Georg and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X
2002.
The neurotrophin receptor p75NTR: novel functions and implications for diseases of the nervous system.
Nature Neuroscience
5
(11)
, pp. 1131-1136.
10.1038/nn1102-1131
|
|
Benzel, Isabel, Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X and Casademunt, Elisabeth
2001.
Strain-specific complementation between NRIF1 and NRIF2, two zinc finger proteins sharing structural and biochemical properties.
Gene
281
(1-2)
, pp. 19-30.
10.1016/S0378-1119(01)00730-2
|
|



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