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Number of items: 46.

O'Mahony, Adam G., Mazzocchi, Martina, Morris, Alex, Morales-Prieto, Noelia, Guinane, Caitriona, Wyatt, Sean L. ORCID: https://orcid.org/0000-0002-0572-234X, Collins, Louise M., Sullivan, Aideen M. and O'Keeffe, Gerard W. 2025. The class-IIa HDAC inhibitor TMP269 promotes BMP-Smad signalling and is neuroprotective in in vitro and in vivo 6-hydroxydopamine models of Parkinson's disease. Neuropharmacology 268 , 110319. 10.1016/j.neuropharm.2025.110319
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Ateaque, Sarah, Merkouris, Spyros, Wyatt, Sean ORCID: https://orcid.org/0000-0002-0572-234X, Allen, Nicholas D. ORCID: https://orcid.org/0000-0003-4009-186X, Xie, Jia, DiStefano, Peter S., Lindsay, Ronald M. and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X 2022. Selective activation and down-regulation of Trk receptors by neurotrophins in human neurons co-expressing TrkB and TrkC. Journal of Neurochemistry 161 (6) , pp. 463-477. 10.1111/jnc.15617
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Mazzocchi, Martina, Goulding, Susan R., Wyatt, Sean L. ORCID: https://orcid.org/0000-0002-0572-234X, Collins, Louise M., Sullivan, Aideen M. and O'Keeffe, Gerard W. 2021. LMK235, a small molecule inhibitor of HDAC4/5, protects dopaminergic neurons against neurotoxin- and α-synuclein-induced degeneration in cellular models of Parkinson's disease. Molecular and Cellular Neuroscience 115 , 103642. 10.1016/j.mcn.2021.103642
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Howard, Laura, Wyatt, Sean ORCID: https://orcid.org/0000-0002-0572-234X and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2021. Neuregulin-4 contributes to the establishment of cutaneous sensory innervation. Developmental Neurobiology 81 (2) , pp. 139-148. 10.1002/dneu.22803
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Goulding, Susan R., Concannon, Ruth M., Morales-Prieto, Noelia, Villalobos-Manriquez, Francisca, Clarke, Gerard, Collins, Louise M., Lévesque, Martin, Wyatt, Sean L. ORCID: https://orcid.org/0000-0002-0572-234X, Sullivan, Aideen M. and O'Keeffe, Gerard W. 2021. Growth differentiation factor 5 exerts neuroprotection in an α-synuclein rat model of Parkinson’s disease. Brain 144 (2) , e14. 10.1093/brain/awaa367
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Anantha, Jayanth, Goulding, Susan R., Wyatt, Sean L. ORCID: https://orcid.org/0000-0002-0572-234X, Concannon, Ruth M., Collins, Louise M., Sullivan, Aideen M. and O'Keeffe, Gerard W. 2020. STRAP and NME1 mediate the neurite growth-promoting effects of the neurotrophic factor GDF5. iScience 23 (9) , 101457. 10.1016/j.isci.2020.101457
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Carriba, Paulina, Wyatt, Sean ORCID: https://orcid.org/0000-0002-0572-234X and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2020. CD40L Reverse signaling influences dendrite spine morphology and expression of PSD-95 and Rho small GTPases. Frontiers in Cell and Developmental Biology 8 , 254. 10.3389/fcell.2020.00254
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O'Keeffe, Gerard W., Sullivan, Aideen M., Hegarty, Shane V., Collins, Louise M., McCarthy, Erin, Wyatt, Sean L. ORCID: https://orcid.org/0000-0002-0572-234X and Alshangiti, Amnah M. 2020. Association of distinct type 1 bone morphogenetic protein receptors with different molecular pathways and survival outcomes in neuroblastoma. Neuronal Signaling 4 (1) , NS20200006. 10.1042/NS20200006
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Calhan, Osman Yipkin, Wyatt, Sean ORCID: https://orcid.org/0000-0002-0572-234X and Davies, Alun Millward ORCID: https://orcid.org/0000-0001-5841-8176 2019. CD40L reverse signaling suppresses prevertebral sympathetic axon growth and tissue innervation. Developmental Neurobiology 79 (11-12) , pp. 949-962. 10.1002/dneu.22735
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Howard, Laura, McWilliams, Thomas G., Wyatt, Sean ORCID: https://orcid.org/0000-0002-0572-234X and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2019. CD40 forward signalling is a physiological regulator of early sensory axon growth. Development 146 (18) , dev176495. 10.1242/dev.176495
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Mazzocchi, Martina, Wyatt, Sean L. ORCID: https://orcid.org/0000-0002-0572-234X, Mercatelli, Daniela, Morari, Michele, Morales-Prieto, Noelia, Collins, Louise M., Sullivan, Aideen M. and O'Keeffe, Gerard W. 2019. Gene co-expression analysis identifies histone deacetylase 5 and 9 expression in midbrain dopamine neurons and as regulators of neurite growth via bone morphogenetic protein signaling. Frontiers in Cell and Developmental Biology 7 , 191. 10.3389/fcell.2019.00191
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Paramo, Blanca, Wyatt, Sean ORCID: https://orcid.org/0000-0002-0572-234X and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2019. Neuregulin-4 is required for the growth and elaboration of striatal medium spiny neuron dendrites. Journal of Neuropathology and Experimental Neurology 78 (8) , pp. 725-734. 10.1093/jnen/nlz046
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Erice, Clara, Calhan, O. Yipkin, Kisiswa, Lilian, Wyatt, Sean ORCID: https://orcid.org/0000-0002-0572-234X and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2019. Regional differences in the contributions of TNF reverse and forward signaling to the establishment of sympathetic innervation. Developmental Neurobiology 79 (4) , pp. 317-334. 10.1002/dneu.22680
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Howard, Laura, Wosnitzka, Erin, Okakpu, Darian, White, Matthew A., Wyatt, Sean ORCID: https://orcid.org/0000-0002-0572-234X and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2018. TWE-PRIL reverse signaling suppresses sympathetic axon growth and tissue innervation. Development 145 (22) , dev165936. 10.1242/dev.165936
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Paramo, Blanca, Wyatt, Sean ORCID: https://orcid.org/0000-0002-0572-234X and Davies, Alun ORCID: https://orcid.org/0000-0001-5841-8176 2018. An essential role for neuregulin-4 in the growth and elaboration of developing neocortical pyramidal dendrites. Experimental Neurology 302 , pp. 85-92. 10.1016/j.expneurol.2018.01.002
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McWilliams, Thomas G., Howard, Laura, Wyatt, Sean ORCID: https://orcid.org/0000-0002-0572-234X and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2017. TNF superfamily member APRIL enhances midbrain dopaminergic axon growth and contributes to the nigrostriatal projection in vivo. Experimental Neurology 298 , pp. 97-103. 10.1016/j.expneurol.2017.09.007
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Kisiswa, Lilian, Erice Jurecky, Clara, Ferron, Laurent, Wyatt, Sean ORCID: https://orcid.org/0000-0002-0572-234X, Osório, Catarina, Dolphin, Annette C. and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2017. T-type Ca 2+ channels are required for enhanced sympathetic axon growth by TNFα reverse signalling. Open Biology 7 (1) , 160288. 10.1098/rsob.160288
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Hegarty, Shane V., Wyatt, Sean ORCID: https://orcid.org/0000-0002-0572-234X, Howard, Laura, Stappers, Elke, Huylebroeck, Danny, Sullivan, Aideen M. and O'Keeffe, Gerard W. 2017. Zeb2 is a negative regulator of midbrain dopaminergic axon growth and target innervation. Scientific Reports 7 (1) , 8568. 10.1038/s41598-017-08900-3
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Harvey, Ann K, Lelos, Mariah Jillian ORCID: https://orcid.org/0000-0001-7102-055X, Greenhill, Claire J., Jones, Ashley, Clinch, Susanne, Newton, Michael, Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578, Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2016. Novel application of behavioral assays allows dissociation of joint pathology from systemic extra-articular alterations induced by inflammatory arthritis. Journal of Rheumatic Diseases and Treatment 2 (2) , 033. 10.23937/2469-5726/1510033
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O'Keeffe, Gerard, Gutierrez, Humberto, Howard, Laura, Laurie, Christopher W., Osorio, Catarina, Gavalda, Nuria, Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2016. Region-specific role of growth differentiation factor-5 in the establishment of sympathetic innervation. Neural Development 11 , 4. 10.1186/s13064-016-0060-3
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Vizard, Thomas Neill, Newton, Michael, Howard, Laura, Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2015. ERK signaling mediates CaSR-promoted axon growth. Neuroscience Letters 603 , pp. 77-83. 10.1016/j.neulet.2015.07.019
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McWilliams, Thomas G., Howard, Laura, Wyatt, Sean ORCID: https://orcid.org/0000-0002-0572-234X and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2015. Regulation of autocrine signaling in subsets of sympathetic neurons has regional effects on tissue innervation. Cell Reports 10 (9) , pp. 1443-1449. 10.1016/j.celrep.2015.02.016
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Walsh, Sinéad, Gavin, Aisling, Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X, O'Connor, Catriona, Keeshan, Karen, Nolan, Yvonne M., O'Keeffe, Gerard W. and Sullivan, Aideen M. 2015. Knockdown of interleukin-1 receptor 1 is not neuroprotective in the 6-hydroxydopamine striatal lesion rat model of Parkinson's disease. International Journal of Neuroscience 125 (1) , pp. 70-77. 10.3109/00207454.2014.904304

Nolan, Aoife M., Collins, Louise M., Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X, Gutierrez, Humberto and O'Keeffe, Gerard W. 2014. The neurite growth inhibitory effects of soluble TNFα on developing sympathetic neurons are dependent on developmental age. Differentiation 88 (4-5) , pp. 124-130. 10.1016/j.diff.2014.12.006

Hegarty, Shane V., Collins, Louise M., Gavin, Aisling M., Roche, Sarah L., Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X, Sullivan, Aideen M. and O'Keeffe, Gerard W. 2014. Canonical BMP–Smad signalling promotes neurite growth in rat midbrain dopaminergic neurons. NeuroMolecular Medicine 16 (2) , pp. 473-489. 10.1007/s12017-014-8299-5

Collins, Louise M, Gavin, Aisling M, Walsh, Sinead, Sullivan, Aideen M, Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X, O'Keeffe, Gerard W., Nolan, Yvonne M. and Toulouse, André 2014. Expression of endogenous Mkp1 in 6-OHDA rat models of Parkinson's disease. SpringerPlus 3 (1) , 205. 10.1186/2193-1801-3-205
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Osório, Catarina Raquel, Chacon Fernandez, Pedro J., White, Matthew, Kisiswa, Lilian ORCID: https://orcid.org/0000-0002-1800-0645, Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X, Rodríguez-Tébar, Alfredo and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2014. Selective regulation of axonal growth from developing hippocampal neurons by tumor necrosis factor superfamily member APRIL. Molecular and Cellular Neuroscience 59 , pp. 24-36. 10.1016/j.mcn.2014.01.002
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Gavin, Aisling M., Walsh, Sinéad, Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X, O'Keeffe, Gerard W. and Sullivan, Aideen M. 2014. 6-Hydroxydopamine induces distinct alterations in GDF5 and GDNF mRNA expression in the rat nigrostriatal system in vivo. Neuroscience Letters 561 , pp. 176-181. 10.1016/j.neulet.2013.12.046

Osorio, Catarina Raquel, Chacon Fernandez, Pedro, Kisiswa, Lilian ORCID: https://orcid.org/0000-0002-1800-0645, White, Matthew, Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X, Rodriguez-Tebar, A. and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2013. Growth differentiation factor 5 is a key physiological regulator of dendrite growth during development. Development 140 (23) , pp. 4751-4762. 10.1242/dev.101378
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Kisiswa, Lilian ORCID: https://orcid.org/0000-0002-1800-0645, Osório, Catarina Raquel, Erice Jurecky, Clara, Vizard, Thomas Neill, Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2013. TNFα reverse signaling promotes sympathetic axon growth and target innervation. Nature Neuroscience 16 (7) , pp. 865-873. 10.1038/nn.3430

Collins, Louise M., O'Keeffe, Gerard W., Long-Smith, Caitriona M., Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X, Sullivan, Aideen M., Toulouse, Andre and Nolan, Yvonne M. 2013. Mitogen-activated protein kinase phosphatase (MKP)-1 as a neuroprotective agent: promotion of the morphological development of midbrain dopaminergic neurons. Neuromolecular Medicine 15 (2) , pp. 435-446. 10.1007/s12017-013-8230-5

Howard, Laura, Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X, Nagappan, Guhan and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2013. ProNGF promotes neurite growth from a subset of NGF-dependent neurons by a p75(NTR)-dependent mechanism. Development 140 (10) , pp. 2108-2117. 10.1242/dev.085266
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Gutierrez, Humberto ORCID: https://orcid.org/0000-0002-5021-8636, Kisiswa, Lilian ORCID: https://orcid.org/0000-0002-1800-0645, O'Keeffe, Gerard W., Smithen, Matthew J., Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2013. Regulation of neurite growth by tumour necrosis superfamily member RANKL. Open Biology 3 (1) , 120150. 10.1098/rsob.120150
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Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X, Spori, Bodo, Vizard, Thomas Neill and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2011. Selective regulation of nerve growth factor expression in developing cutaneous tissue by early sensory innervation. Neural Development 6 , 18. 10.1186/1749-8104-6-18
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Franklin, Sarah Louise, Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 and Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X 2009. Macrophage stimulating protein is a neurotrophic factor for a sub-population of adult nociceptive sensory neurons. Molecular and Cellular Neuroscience 41 (2) , pp. 175-185. 10.1016/j.mcn.2009.02.009

Andres, R., Herraez-Baranda, Luis Antonio, Thompson, J., Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2008. Regulation of sympathetic neuron differentiation by endogenous nerve growth factor and neurotrophin-3. Neuroscience Letters 431 (3) , pp. 241-246. 10.1016/j.neulet.2007.11.045

Andres, R., Herraez-Baranda, Luis Antonio, Thompson, J., Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X and Davies, Alun M ORCID: https://orcid.org/0000-0001-5841-8176 2008. Regulation of developing sympathetic neuron phenotype by endogenous NGF and NT3. Neuroscience Letters 431 (3) , pp. 241-246. 10.1016/j.neulet.2007.11.045

Hefti, F. F., Rosenthal, A., Walicke, P. A., Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X, Vergara, G., Shelton, S. and Davies, Alun M ORCID: https://orcid.org/0000-0001-5841-8176 2006. Novel class of pain drugs based on antagonism of NGF. Trends in Pharmacological Sciences 27 (2) , pp. 85-91. 10.1016/j.tips.2005.12.001

Forgie, Alison, Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X, Correll, Pamela H. and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2003. Macrophage stimulating protein is a target-derived neurotrophic factor for developing sensory and sympathetic neurons. Development 130 (5) , pp. 995-1002. 10.1242/dev.00329

Cowen, T., Woodhoo, A., Sullivan, C. D., Jolly, R., Crutcher, K. A., Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X, Michael, G. J., Orike, N., Gatzinsky, K. and Thrasivoulou, C. 2003. Reduced age-related plasticity of neurotrophin receptor expression in selected sympathetic neurons of the rat. Aging Cell 2 (1) , pp. 59-70. 10.1046/j.1474-9728.2003.00035.x

Andres, Rosa, Forgie, Alison, Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X, Chen, Qi, de Sauvage, Frederic J. and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2001. Multiple effects of artemin on sympathetic neurone generation, survival and growth. Development 128 (19) , pp. 3685-3695.

Middleton, Gayle, Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X, Ninkina, Natalia ORCID: https://orcid.org/0000-0001-8570-5648 and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2001. Reciprocal developmental changes in the roles of Bcl-w and Bcl-x(L) in regulating sensory neuron survival. Development 128 (3) , pp. 447-457.

Alonzi, Tonino, Middleton, Gayle, Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X, Buchman, Vladimir L. ORCID: https://orcid.org/0000-0002-7631-8352, Ulrich, A. K. Betz, Muller, Werner, Musiani, Piero, Poli, Valeria and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2001. Role of STAT3 and PI 3-Kinase/Akt in mediating the survival actions of cytokines on sensory neurons. Molecular and Cellular Neuroscience 18 (3) , pp. 270-282. 10.1006/mcne.2001.1018

Middleton, Gayle, Hamanoue, Makoto, Enokido, Yasushi, Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X, Pennica, Diane, Jaffray, Ellis, Hay, Ronald T. and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2000. Cytokine-induced nuclear factor kappa B activation promotes the survival of developing neurons. Journal of cell biology 148 (2) , pp. 325-332. 10.1083/jcb.148.2.325

Middleton, Gayle, Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X, Cox, Andrew, Korsmeyer, Stanley and Davies, Alun ORCID: https://orcid.org/0000-0001-5841-8176 2000. Differences in Bcl-2- and Bax-independent function in regulating apoptosis in sensory neuron populations. European Journal of Neuroscience 12 (3) , pp. 819-827. 10.1046/j.1460-9568.2000.00966.x

Forgie, Alison, Kuehnel, Florian, Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2000. In vivo survival requirement of a subset of nodose ganglion neurons for nerve growth factor. European Journal of Neuroscience 12 (2) , pp. 670-676. 10.1046/j.1460-9568.2000.00951.x

This list was generated on Sat Nov 1 12:04:46 2025 GMT.


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