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Number of items: 55.

Wang, Wenjing, Liew, Wei Lin, Huang, Shiqi, Chan, Edmund, Li Min Tan, Amelia, Tian, Chi, Tong, Yihan, Zhang, Yuntian, Liu, Fei, Qin, Yixian, Jun Leong Ou, Sean, Sadananthan, Suresh Anand, Velan, Sambasivam Sendhil, Venkataraman, Kavita, Langley, Sarah

, Enrico, Petretto, Hoon, Shawn, Tham, Kwang Wei, Chong, Yap Seng, Lee, Yung Seng, Leow, Melvin Khee-Shing, Sim, Xueling, Khoo, Chin Meng, Tai, E Shyong, Khoo, Eric Yin Hao, Liu, Mei Hui and Liu, Boxiang 2025. Impact of polymorphisms on gene expression and splicing in response to exercise and diet-induced weight loss in human skeletal muscle tissues. Cell Genomics 5 (9) , 100951. 10.1016/j.xgen.2025.100951

Wazny, Vanessa Kristina, Mahadevan, Aparna, Nguyen, Nhi, Wee, Hannah, Vipin, Ashwati, Lam, Tammy, Tay, Kai Yi, See, Jia-Xiang, Gurveen, Sandhu, Leow, Yi Jin, D'Agnostino, Guiseppe, Graf, Martin, Sivakumar, Aravind, Lin, Sichen, Phuc, Nguyen Cao Thien, Chen, James Xiao Yuan, Langley, Sarah R.

, Ang, Lay Teng, Loh, Kyle M., Kandiah, Nagaendran, Augustine, George J. and Cheung, Christine 2025. Chronic cerebral hypoperfusion induces venous dysfunction via EPAS1 regulation in mice. Nature Communications 16 , 6302. 10.1038/s41467-025-61614-3

Lai, Kei Onn, Wong, Jia Hui, Tham, Nevin, Fairley, Lauren, Ratnakar Naik, Roshan, Wang, Yulan, Langley, Sarah R.

and Barron, Anna M. 2025. Age-dependent regulation of hippocampal inflammation by the mitochondrial translocator protein in mice. Aging Cell 24 (6) , e70039. 10.1111/acel.70039

Leu, Costin, Avbersek, Andreja, Stevelink, Remi, Custodio, Helena Martins, Chen, Siwei, Speed, Doug, Bennett, Caitlin A., Jonsson, Lina, Unnsteinsdóttir, Unnur, Jorgensen, Andrea L., Cavalleri, Gianpiero L., Delanty, Norman, Craig, John J., Depondt, Chantal, Johnson, Michael R., Koeleman, Bobby P.C., Hassanin, Emadeldin, Omidvar, Maryam Erfanian, Krause, Roland, Lerche, Holger, Marson, Anthony G., O'Brien, Terence J., Sander, Josemir W., Sills, Graeme J., Striano, Pasquale, Zara, Federico, Stefansson, Hreinn, Stefansson, Kari, May, Patrick, Neale, Benjamin M., Lal, Dennis, Berkovic, Samuel F., Amadori, Elisabetta, Andrade, Danielle M., Annesi, Grazia, Balagura, Ganna, Balestrini, Simona, Barba, Carmen, Barboza, Karen, Baumgartner, Tobias H., Baykan, Betül, Bebek, Nerses, Becker, Felicitas, Bennett, Caitlin A., Berkovic, Samuel F., Beydoun, Ahmad, Bisulli, Francesca, Borggräfe, Ingo, Bosselmann, Christian, Busch, Robyn M., Canafoglia, Laura, Castellotti, Barbara, Chou, I-Jun, Chung, Seo-Kyung, Cotsapas, Chris, Devinsky, Orrin, Dlugos, Dennis J., Doccini, Viola, Doherty, Colin P., Ellis, Colin A., El-Naggar, Hany, Evans, Meghan, Ferraro, Thomas N., Fitzgerald, Mark, Fortunato, Francesco, French, Jacqueline A., Freri, Elena, Gagliardi, Monica, Gambardella, Antonio, Goldman, Alica, Granata, Tiziana, Gupta, Namrata, Haas, Kevin, Hirose, Shinichi, Hoeper, Olivia, Hung, Po-Chen, Johnson, Michael R., Khoueiry-Zgheib, Nathalie, Khoury, Jean, Klein, Karl Martin, Knake, Susanne, Koupparis, Andreas, Kousiappa, Ioanna, Krause, Roland, Kunz, Wolfram S., Kuzniecky, Ruben I., Kwan, Patrick, Labate, Angelo, Lacey, Austin, Lal, Dennis, Lauxmann, Stephan, Lawthom, Charlotte, Lerche, Holger, Leu, Costin, Lewis-Smith, David, Liao, Calwing, Lin, Chih-Hsiang, Lin, Kuang-Lin, Linnankivi, Tarja, Lowenstein, Daniel H., Lui, Colin H.T., Madia, Francesca, Magri, Stefania, Maillard, Louis, Manna, Lorella, Marques, Paula, Mayer, Thomas, McGraw, Christopher M., Meador, Kimford J., Mei, Davide, Minardi, Raffaella, Mostacci, Barbara, Muccioli, Lorenzo, Müller-Schlüter, Karen, Nasreddine, Wassim, Neale, Benjamin M., Neubauer, Bernd A., Papacostas, Savvas S., Parrini, Elena, Pendziwiat, Manuela, Petrovski, Slavé, Pickrell, William O., Powell, Robert H.W., Ragona, Francesca, Rees, Mark I., Rheims, Sylvain, Riva, Antonella, Rosenow, Felix, Ryvlin, Philippe, Sadleir, Lynette G., Salman, Bar??, Salmon, Andrea, Sammarra, Ilaria, Scala, Marcello, Scheffer, Ingrid E., Schubert-Bast, Susanne, Schulze-Bonhage, Andreas, Shiedley, Beth R., Sisodiya, Sanjay M., Sperling, Michael R., Steinhoff, Bernhard J., Stephani, Ulrich, Striano, Pasquale, Strzelczyk, Adam, Surges, Rainer, Suzuki, Toshimitsu, Talarico, Mariagrazia, Taneja, Randip S., Tanteles, George A., Tsai, Meng-Han, Tumiene, Birute, Turkdogan, Dilsad, Valton, Luc, van Baalen, Andreas, Vetro, Annalisa, von Wrede, Randi, Wagner, Ryan G., Weber, Yvonne G., Weckhuysen, Sarah, Widdess-Walsh, Peter, Wiebe, Samuel, Wolking, Stefan, Yamakawa, Kazuhiro, Yap?c?, Zuhal, Zahnert, Felix, Zara, Federico, Zizovic, Milena, Zsurka, Gábor, Ali, Quratulain Zulfiqar, Auce, Pauls, Avbersek, Andreja, Balling, Rudi, Becker, Felicitas, Berghuis, Bianca, Borghei, Mojgansadat, Brodie, Martin J., Campbell, Ellen, Cavalleri, Gianpiero L., Chinthapalli, Krishna, Coppola, Antonietta, Craig, John, Delanty, Norman, Demurtas, Rita, Depondt, Chantal, Francis, Ben, Gambardella, Antonio, Gudmundsson, Lárus J., Heggeli, Kristin, Hengsbach, Christian, Hutton, Jane L., Ingason, Andrés, Johnson, Michael R., Jorgensen, Andrea, Klein, Karl M., Koeleman, Bobby P.C., Krause, Roland, Krenn, Martin, Kunz, Wolfram S., Langley, Sarah R.

, Lerche, Holger, Leu, Costin, Marson, Anthony G., McCormack, Mark, Møller, Rikke S., Morris, Andrew, Muhle, Hiltrud, Nikanorova, Marina, O'Brien, Terence J., Petrovski, Slave, Rau, Sarah, Rener-Primec, Zvonka, Sander, Josemir W., Sargsyan, Narek, Schneider, Reinhard, Sills, Graeme J., Sisodiya, Sanjay M., Speed, Doug, Srivastava, Prashant K., Stefansson, Hreinn, Stefánsson, Kári, Striano, Pasquale, Todaro, Marian, Weber, Yvonne G., Weckhuysen, Sarah, Willis, Joseph, Wolking, Stefan, Zara, Federico, Zimprich, Fritz and Sisodiya, Sanjay M. 2025. Genome-wide association meta-analyses of drug-resistant epilepsy. EBioMedicine 115 , 105675. 10.1016/j.ebiom.2025.105675

Yadav, Manisha, AlQazzaz, Mona A., Ciamponi, Felipe E., Ho, Jolene C., Maron, Maxim I., Sababi, Aiden M., MacLeod, Graham, Ahmadi, Moloud, Bullivant, Garrett, Tano, Vincent, Langley, Sarah R.

, Sánchez-Osuna, María, Sachamitr, Patty, Kushida, Michelle, Bardile, Costanza Ferrari, Pouladi, Mahmoud A., Kurtz, Rebecca, Richards, Laura, Pugh, Trevor, Tyers, Mike, Angers, Stephane, Dirks, Peter B., Bader, Gary D., Truant, Ray, Massirer, Katlin B., Barsyte-Lovejoy, Dalia, Shechter, David, Harding, Rachel J., Arrowsmith, Cheryl H. and Prinos, Panagiotis 2025. PRMT5 promotes full-length HTT expression by repressing multiple proximal intronic polyadenylation sites. Nucleic Acids Research 53 (8) , gkaf347. 10.1093/nar/gkaf347

Zalivina, Irina, Barwari, Temo, Yin, Xiaoke, Langley, Sarah R.

, Barallobre-Barreiro, Javier, Wakimoto, Hiroko, Zampetaki, Anna, Mayr, Manuel, Avkiran, Metin and Eminaga, Seda 2023. Inhibition of miR-199a-3p in a murine hypertrophic cardiomyopathy (HCM) model attenuates fibrotic remodeling. Journal of Molecular and Cellular Cardiology Plus 6 , 100056. 10.1016/j.jmccpl.2023.100056

Utami, Kagistia Hana, Yusof, Nur Amirah Binte Muhammed, Garcia-Miralles, Marta, Skotte, Niels Henning, Nama, Srikanth, Sampath, Prabha, Langley, Sarah R.

and Pouladi, Mahmoud A. 2023. Dysregulated COMT expression in fragile X syndrome. NeuroMolecular Medicine 25 (4) , pp. 644-649. 10.1007/s12017-023-08754-1

Tano, Vincent, Utami, Kagistia Hana, Yusof, Nur Amirah Binte Mohammad, Bégin, Jocelyn, Tan, Willy Wei Li, Pouladi, Mahmoud A. and Langley, Sarah R.

2023. Widespread dysregulation of mRNA splicing implicates RNA processing in the development and progression of Huntington's disease. EBioMedicine 94 , 104720. 10.1016/j.ebiom.2023.104720

Fairley, Lauren H., Lai, Kei Onn, Wong, Jia Hui, Chong, Wei Jing, Vincent, Anselm Salvatore, D'Agostino, Giuseppe, Wu, Xiaoting, Naik, Roshan R., Jayaraman, Anusha, Langley, Sarah R.

, Ruedl, Christiane and Barron, Anna M. 2023. Mitochondrial control of microglial phagocytosis by the translocator protein and hexokinase 2 in Alzheimer's disease. Proceedings of the National Academy of Sciences 120 (8) , e2209177120. 10.1073/pnas.2209177120

Tham, Nevin and Langley, Sarah R.

2022. Evaluating the robustness of connectivity methods to noise for in silico drug repurposing studies. Frontiers in Systems Biology 2 , 1050730. 10.3389/fsysb.2022.1050730

Ziaei, Amin, Garcia-Miralles, Marta, Radulescu, Carola I., Sidik, Harwin, Silvin, Aymeric, Bae, Han-Gyu, Bonnard, Carine, Yusof, Nur Amirah Binte Mohammad, Ferrari Bardile, Costanza, Tan, Liang Juin, Ng, Alvin Yu Jin, Tohari, Sumanty, Dehghani, Leila, Henry, Lily, Yeo, Xin Yi, Lee, Sejin, Venkatesh, Byrappa, Langley, Sarah R.

, Shaygannejad, Vahid, Reversade, Bruno, Jung, Sangyong, Ginhoux, Florent and Pouladi, Mahmoud A. 2022. Ermin deficiency leads to compromised myelin, inflammatory milieu, and susceptibility to demyelinating insult. Brain Pathology 32 (5) , e13064. 10.1111/bpa.13064

Bao, Xuanwen, Li, Qiong, Chen, Jinzhang, Chen, Diyu, Ye, Chanqi, Dai, Xiaomeng, Wang, Yanfang, Li, Xin, Rong, Xiaoxiang, Cheng, Fei, Jiang, Ming, Zhu, Zheng, Ding, Yongfeng, Sun, Rui, Liu, Chuan, Huang, Lingling, Jin, Yuzhi, Li, Bin, Lu, Juan, Wu, Wei, Guo, Yixuan, Fu, Wenguang, Langley, Sarah Raye

, Tano, Vincent, Fang, Weijia, Guo, Tiannan, Sheng, Jianpeng, Zhao, Peng and Ruan, Jian 2022. Molecular subgroups of intrahepatic cholangiocarcinoma discovered by single-cell RNA sequencing–assisted multiomics analysis. Cancer Immunology Research 10 (7) , 811–828. 10.1158/2326-6066.CIR-21-1101

Chothani, Sonia P., Adami, Eleonora, Widjaja, Anissa A., Langley, Sarah R.

, Viswanathan, Sivakumar, Pua, Chee Jian, Zhihao, Nevin Tham, Harmston, Nathan, D'Agostino, Giuseppe, Whiffin, Nicola, Mao, Wang, Ouyang, John F., Lim, Wei Wen, Lim, Shiqi, Lee, Cheryl Q.E., Grubman, Alexandra, Chen, Joseph, Kovalik, J.P., Tryggvason, Karl, Polo, Jose M., Ho, Lena, Cook, Stuart A., Rackham, Owen J.L. and Schafer, Sebastian 2022. A high-resolution map of human RNA translation. Molecular Cell 82 (15) , pp. 2885-2899. 10.1016/j.molcel.2022.06.023

Basnakova, Adriana, Cheng, Ruey-Kuang, Chia, Joanne Shu Ming, D'Agostino, Giuseppe, Suryadi, Tan, Germaine Jia Hui, Langley, Sarah R.

and Jesuthasan, Suresh 2021. The habenula clock influences response to a stressor. Neurobiology of Stress 15 , 100403. 10.1016/j.ynstr.2021.100403

Trott, Jamie, Alpagu, Yunus, Tan, Ee Kim, Shboul, Mohammad, Dawood, Yousif, Elsy, Michael, Wollmann, Heike, Tano, Vincent, Bonnard, Carine, Eng, Shermaine, Narayanan, Gunaseelan, Junnarkar, Seetanshu, Wearne, Stephen, Strutt, James, Kumar, Aakash, Tomaz, Lucian B., Goy, Pierre-Alexis, Mzoughi, Slim, Jennings, Rachel, Hagoort, Jaco, Eskin, Ascia, Lee, Hane, Nelson, Stanley F., Al-Kazaleh, Fawaz, El-Khateeb, Mohammad, Fathallah, Rajaa, Shah, Harsha, Goeke, Jonathan, Langley, Sarah R.

, Guccione, Ernesto, Hanley, Neil, De Bakker, Bernadette S., Reversade, Bruno and Dunn, N. Ray 2020. Mitchell-Riley syndrome iPSC exhibit reduced pancreatic endoderm differentiation due to an RFX6 mutation. Development 147 (21) 10.1242/dev.194878

Zhang, Jinqiu, Ooi, Jolene, Utama, Kagistia Hana, Langley, Sarah R.

, Akwasi Aning, Obed, Shin Park, Dong, Renner, Magdalena, Ma, Shiming, Cheok, Chit Fang, Knoblich, Juergen A., Ginhoux, Florent, Petretto, Enrico and Pouladi, Mahmoud A. 2019. Expanded huntingtin CAG repeats disrupt the balance between neural progenitor expansion and differentiation in human cerebral organoids. [Online]. bioRXiv. Available at: https://doi.org/10.1101/850586

Laaniste, Liisi, Srivastava, Prashant K., Stylianou, Julianna, Syed, Nelofer, Cases-Cunillera, Silvia, Shkura, Kirill, Zeng, Qingyu, Rackham, Owen J. L., Langley, Sarah R.

, Delahaye-Duriez, Andree, O'Neill, Kevin, Williams, Matthew, Becker, Albert, Roncaroli, Federico, Petretto, Enrico and Johnson, Michael R. 2019. Integrated systems-genetic analyses reveal a network target for delaying glioma progression. Annals of Clinical and Translational Neurology 6 (9) , pp. 1616-1638. 10.1002/acn3.50850

Chothani, Sonia, Schafer, Sebastian, Adami, Eleonora, Viswanathan, S., Widjaja, Anissa A., Langley, Sarah R.

, Tan, Jessie, Wang, Mao, Quaife, Nicholas M., Pua, Chee Jian, D'Agostino, Guiseppe, Shekeran, Shamini Guna, George, Benjamin L., Lim, Stella, Cao, Elaine Yiqun, van Heesch, Sebastiaan, Witte, Franziska, Felkin, Leanne E., Christodoulou, Eleni G., Dong, Jinrui, Blachut, Susanne, Patone, Giannino, Barton, Paul J. R., Hubner, Norbert, Cook, Stuart A. and Rackham, Owen J. L. 2019. Widespread translational control of fibrosis in the human heart by RNA-binding proteins. Circulation 140 (11) , pp. 937-951. 10.1161/CIRCULATIONAHA.119.039596

Bardile, Costanza Ferrari, Garcia-Miralles, Marta, Caron, Nicholas S., Rayan, Nirmala Arul, Langley, Sarah R.

, Harmston, Nathan, Rondelli, Ana Maria, Teo, Roy Tang Yi, Waltl, Sabine, Anderson, Lisa M., Bae, Han-Gyu, Jung, Sangyong, Williams, Anna, Prabhakar, Shyam, Petretto, Enrico, Hayden, Michael R. and Pouladi, Mahmoud A. 2019. Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral abnormalities in Huntington disease. Proceedings of the National Academy of Sciences of the United States of America 116 (19) , pp. 9622-9627. 10.1073/pnas.1818042116

Tan, Amelia Li Min, Langley, Sarah R

, Tan, Chee Fan, Chai, Jin Fang, Khoo, Chin Meng, Leow, Melvin Khee-Shing, Khoo, Eric Yin Hao, Moreno-Moral, Aida, Pravenec, Michal, Rotival, Maxime, Sadananthan, Suresh Anand, Velan, S Sendhil, Venkataraman, Kavita, Chong, Yap Seng, Lee, Yung Seng, Sim, Xueling, Stunkel, Walter, Liu, Mei Hui, Tai, E Shyong and Petretto, Enrico 2019. Ethnicity-specific skeletal muscle transcriptional signatures and their relevance to insulin resistance in Singapore. The Journal of Clinical Endocrinology & Metabolism 104 (2) , pp. 465-486. 10.1210/jc.2018-00309

Ooi, Jolene, Langley, Sarah

, Xu, Xiaohong, Utami, Kagistia H., Sim, Bernice, Huang, Yihui, Harmston, Nathan P., Tay, Yi Lin, Ziaei, Amin, Zeng, Ruizhu, Low, Donovan, Aminkeng, Folefac, Sobata, Radoslaw M., Ginhoux, Florent, Petretto, Enrico and Pouladi, Mahmoud A. 2019. Unbiased profiling of Isogenic Huntington Disease hPSC-Derived CNS and peripheral cells reveals strong cell-type specificity of CAG length effects. Cell Reports 26 (9) , pp. 2494-2508. 10.1016/j.celrep.2019.02.008

Barwari, Temo, Eminaga, Seda, Mayr, Ursula, Lu, Ruifang, Armstrong, Paul C., Chan, Melissa V., Sahraei, Mahnaz, Fernández-Fuertes, Marta, Moreau, Thomas, Barallobre-Barreiro, Javier, Lynch, Marc, Yin, Xiaoke, Schulte, Christian, Baig, Ferheen, Pechlaner, Raimund, Langley, Sarah R.

, Zampetaki, Anna, Santer, Peter, Weger, Martin, Plasenzotti, Roberto, Schosserer, Markus, Grillari, Johannes, Kiechl, Stefan, Willeit, Johann, Shah, Ajay M, Ghevaert, Cedric, Warner, Timothy D., Fernández-Hernando, Carlos, Suárez, Yajaira and Mayr, Manuel 2018. Inhibition of profibrotic microRNA-21 affects platelets and their releasate. JCI Insight 3 (21) , e123335. 10.1172/jci.insight.123335

Chothani, Sonia, Schafer, Sebastian, Adami, Eleonora, Viswnathan, Sivakumar, Widjaja, Anissa A., Langley, Sarah R.

, Tan, Jessie, Pua, Chee Jian, D’Agostino, Giuseppe, Van Heesch, Sebastiaan, Witte, Franziska, Felkin, Leanne E., Christodoulou, Eleni G., Dong, JInrui, Blachut, Susanne, Patone, Giannino, Barton, Paul J. R., Hubner, Norbert, Cook, Stuart A. and Rackham, Owen J. L. 2018. Translational control of cardiac fibrosis. [Online]. bioRXiv. Available at: https://doi.org/10.1101/451666

May, Patrick, Girard, Simon, Harrer, Merle, Bobbili, Dheeraj R, Schubert, Julian, Wolking, Stefan, Becker, Felicitas, Lachance-Touchette, Pamela, Meloche, Caroline, Gravel, Micheline, Niturad, Cristina E, Knaus, Julia, De Kovel, Carolien, Toliat, Mohamad, Polvi, Anne, Iacomino, Michele, Guerrero-López, Rosa, Baulac, Stéphanie, Marini, Carla, Thiele, Holger, Altmüller, Janine, Jabbari, Kamel, Ruppert, Ann-Kathrin, Jurkowski, Wiktor, Lal, Dennis, Rusconi, Raffaella, Cestèle, Sandrine, Terragni, Benedetta, Coombs, Ian D, Reid, Christopher A, Striano, Pasquale, Caglayan, Hande, Siren, Auli, Everett, Kate, Møller, Rikke S, Hjalgrim, Helle, Muhle, Hiltrud, Helbig, Ingo, Kunz, Wolfram S, Weber, Yvonne G, Weckhuysen, Sarah, De Jonghe, Peter, Sisodiya, Sanjay M, Nabbout, Rima, Franceschetti, Silvana, Coppola, Antonietta, Vari, Maria S, Trenité, Dorothée Kasteleijn-Nolst, Baykan, Betul, Ozbek, Ugur, Bebek, Nerses, Klein, Karl M, Rosenow, Felix, Nguyen, Dang K, Dubeau, François, Carmant, Lionel, Lortie, Anne, Desbiens, Richard, Clément, Jean-François, Cieuta-Walti, Cécile, Sills, Graeme J, Auce, Pauls, Francis, Ben, Johnson, Michael R, Marson, Anthony G, Berghuis, Bianca, Sander, Josemir W, Avbersek, Andreja, McCormack, Mark, Cavalleri, Gianpiero L, Delanty, Norman, Depondt, Chantal, Krenn, Martin, Zimprich, Fritz, Peter, Sarah, Nikanorova, Marina, Kraaij, Robert, van Rooij, Jeroen, Balling, Rudi, Ikram, M Arfan, Uitterlinden, André G, Avanzini, Giuliano, Schorge, Stephanie, Petrou, Steven, Mantegazza, Massimo, Sander, Thomas, LeGuern, Eric, Serratosa, Jose M, Koeleman, Bobby P C, Palotie, Aarno, Lehesjoki, Anna-Elina, Nothnagel, Michael, Nürnberg, Peter, Maljevic, Snezana, Zara, Federico, Cossette, Patrick, Krause, Roland, Lerche, Holger, Ferlazzo, Edoardo, di Bonaventura, Carlo, La Neve, Angela, Tinuper, Paolo, Bisulli, Francesca, Vignoli, Aglaia, Capovilla, Giuseppe, Crichiutti, Giovanni, Gambardella, Antonio, Belcastro, Vincenzo, Bianchi, Amedeo, Yalçın, Destina, Dizdarer, Gulsen, Arslan, Kezban, Yapıcı, Zuhal, Kuşcu, Demet, Leu, Costin, Heggeli, Kristin, Willis, Joseph, Langley, Sarah R

, Jorgensen, Andrea, Srivastava, Prashant, Rau, Sarah, Hengsbach, Christian and Sonsma, Anja C.M. 2018. Rare coding variants in genes encoding GABAA receptors in genetic generalised epilepsies: an exome-based case-control study. The Lancet. Neurology 17 (8) , pp. 699-708. 10.1016/s1474-4422(18)30215-1

McCormack, Mark, Gui, Hongsheng, Ingason, Andrés, Speed, Doug, Wright, Galen E.B., Zhang, Eunice J., Secolin, Rodrigo, Yasuda, Clarissa, Kwok, Maxwell, Wolking, Stefan, Becker, Felicitas, Rau, Sarah, Avbersek, Andreja, Heggeli, Kristin, Leu, Costin, Depondt, Chantal, Sills, Graeme J., Marson, Anthony G., Auce, Pauls, Brodie, Martin J., Francis, Ben, Johnson, Michael R., Koeleman, Bobby P.C., Striano, Pasquale, Coppola, Antonietta, Zara, Federico, Kunz, Wolfram S., Sander, Josemir W., Lerche, Holger, Klein, Karl Martin, Weckhuysen, Sarah, Krenn, Martin, Gudmundsson, Lárus J., Stefánsson, Kári, Krause, Roland, Shear, Neil, Ross, Colin J.D, Delanty, Norman, Pirmohamed, Munir, Carleton, Bruce C., Cendes, Fernando, Lopes-Cendes, Iscia, Liao, Wei-ping, O'Brien, Terence J., Sisodiya, Sanjay M., Cherny, Stacey, Kwan, Patrick, Baum, Larry, Cavalleri, Gianpiero L., EpiPGX Consortium, EPIGEN Consortium, Canadian Pharmacogenomics Network for Drug Safety, International League Against Epilepsy Consortium on Complex Epil and Langley, Sarah R.

2018. Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients. Neurology 90 (4) , e332-e341. 10.1212/WNL.0000000000004853

Berghuis, Bianca, van der Palen, Job, de Haan, Gerrit-Jan, Lindhout, Dick, Koeleman, Bobby P. C., Sander, Josemir W., The EpiPGX Consortium and Langley, Sarah R.

2017. Carbamazepine- and oxcarbazepine-induced hyponatremia in people with epilepsy. Epilepsia 58 (7) , pp. 1227-1233. 10.1111/epi.13777

Langley, Sarah R.

, Willeit, Karin, Didangelos, Athanasios, Matic, Ljubica Perisic, Skroblin, Philipp, Barallobre-Barreiro, Javier, Lengquist, Mariette, Rungger, Gregor, Kapustin, Alexander, Kedenko, Ludmilla, Molenaar, Chris, Lu, Ruifang, Barwari, Temo, Suna, Gonca, Yin, Xiaoke, Iglseder, Bernhard, Paulweber, Bernhard, Willeit, Peter, Shalhoub, Joseph, Pasterkamp, Gerard, Davies, Alun H., Monaco, Claudia, Hedin, Ulf, Shanahan, Catherine M., Willeit, Johann, Kiechl, Stefan and Mayr, Manuel 2017. Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques. Journal of Clinical Investigation 127 (4) , 1546–1560. 10.1172/JCI86924

Rackham, Owen J L, Langley, Sarah R

, Oates, Thomas, Vradi, Eleni, Harmston, Nathan, Srivastava, Prashant K., Behmoaras, Jacques, Dellaportas, Petros, Bottolo, Leonardo and Petretto, Enrico 2017. A Bayesian approach for analysis of whole-genome Bisulfite sequencing data identifies disease-associated changes in DNA Methylation. Genetics 205 (4) , 1443–1458. 10.1534/genetics.116.195008

Kumar Srivastava, Prashant, Bagnati, Marta, Delahaye-Duriez, Andree, Ko, Jeong-Hun, Rotival, Maxime, Langley, Sarah R.

, Shkura, Kirill, Mazzuferi, Manuela, Danis, Bénédicte, van Eyll, Jonathan, Foerch, Patrik, Behmoaras, Jacques, Kaminski, Rafal M., Petretto, Enrico and Johnson, Michael R. 2017. Genome-wide analysis of differential RNA editing in epilepsy. Genome Research 27 (3) , pp. 440-450. 10.1101/gr.210740.116

Rackham, Owen J. L., Langley, Sarah R.

, Oates, Thomas, Vradi, Eleni, Harmston, Nathan, Srivastava, Prashant K., Behmoaras, Jacques, Dellaportas, Petros, Bottolo, Leonardo and Petretto, Enrico 2017. A Bayesian approach for analysis of whole-genome bisulphite sequencing data identifies disease-associated changes in DNA methylation. [Online]. BioRXiv. Available at: https://doi.org/10.1101/041715

Delahaye-Duriez, Andree, Srivastava, Prashant, Shkura, Kirill, Langley, Sarah R.

, Laaniste, Liisi, Moreno-Moral, Aida, Danis, Bénédicte, Mazzuferi, Manuela, Foerch, Patrik, Gazina, Elena V., Richards, Kay, Petrou, Steven, Kaminski, Rafal M., Petretto, Enrico and Johnson, Michael R. 2016. Rare and common epilepsies converge on a shared gene regulatory network providing opportunities for novel antiepileptic drug discovery. Genome Biology 17 , 245. 10.1186/s13059-016-1097-7

Gomes, Renata S.M., Skroblin, Philipp, Munster, Alex B., Tomlins, Hannah, Langley, Sarah R.

, Zampetaki, Anna, Yin, Xiaoke, Wardle, Fiona C. and Mayr, Manuel 2016. "Young at heart": regenerative potential linked to immature cardiac phenotypes. Journal of Molecular and Cellular Cardiology 92 , pp. 105-108. 10.1016/j.yjmcc.2016.01.026

Johnson, Michael R, Shkura, Kirill, Langley, Sarah R

, Delahaye-Duriez, Andree, Srivastava, Prashant, Hill, W David, Rackham, Owen J L, Davies, Gail, Harris, Sarah E, Moreno-Moral, Aida, Rotival, Maxime, Speed, Doug, Petrovski, Slavé, Katz, Anaïs, Hayward, Caroline, Porteous, David J, Smith, Blair H, Padmanabhan, Sandosh, Hocking, Lynne J, Starr, John M, Liewald, David C, Visconti, Alessia, Falchi, Mario, Bottolo, Leonardo, Rossetti, Tiziana, Danis, Bénédicte, Mazzuferi, Manuela, Foerch, Patrik, Grote, Alexander, Helmstaedter, Christoph, Becker, Albert J, Kaminski, Rafal M, Deary, Ian J and Petretto, Enrico 2016. Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease. Nature Neuroscience 19 , pp. 223-232. 10.1038/nn.4205

Kaudewitz, Dorothee, Skroblin, Philipp, Bender, Lukas H., Barwari, Temo, Willeit, Peter, Pechlaner, Raimund, Sunderland, Nicholas P., Willeit, Karin, Morton, Allison C., Armstrong, Paul C., Chan, Melissa V., Lu, Ruifang, Yin, Xiaoke, Gracio, Filipe, Dudek, Katarzyna, Langley, Sarah R.

, Zampetaki, Anna, de Rinaldis, Emanuele, Ye, Shu, Warner, Timothy D., Saxena, Alka, Kiechl, Stefan, Storey, Robert F. and Mayr, Manuel 2016. Association of MicroRNAs and YRNAs with platelet function. Circulation Research 118 (3) , pp. 420-432. 10.1161/CIRCRESAHA.114.305663

Zampetaki, Anna, Willeit, Peter, Burr, Simon, Yin, Xiaoke, Langley, Sarah R.

, Kiechl, Stefan, Klein, Ronald, Rossing, Peter, Chaturvedi, Nishi and Mayr, Manuel 2016. Angiogenic microRNAs Linked to Incidence and Progression of Diabetic Retinopathy in Type 1 Diabetes. Diabetes 65 (1) , pp. 216-227. 10.2337/db15-0389

Langley, Sarah R.

and Mayr, Manuel 2015. Comparative analysis of statistical methods used for detecting differential expression in label-free mass spectrometry proteomics. Journal of Proteomics 129 , pp. 83-92. 10.1016/j.jprot.2015.07.012

Roncon, Paolo, Soukupovà, Marie, Binaschi, Anna, Falcicchia, Chiara, Zucchini, Silvia, Ferracin, Manuela, Langley, Sarah R.

, Petretto, Enrico, Johnson, Michael R., Marucci, Gianluca, Michelucci, Roberto, Rubboli, Guido and Simonato, Michele 2015. MicroRNA profiles in hippocampal granule cells and plasma of rats with pilocarpine-induced epilepsy--comparison with human epileptic samples. Scientific Reports 5 , 14143. 10.1038/srep14143

Johnson, Michael R., Behmoaras, Jacques, Bottolo, Leonardo, Krishnan, Michelle L., Pernhorst, Katharina, Santoscoy, Paola L. Meza, Rossetti, Tiziana, Speed, Doug, Srivastava, Prashant K., Chadeau-Hyam, Marc, Hajji, Nabil, Dabrowska, Aleksandra, Rotival, Maxime, Razzaghi, Banafsheh, Kovac, Stjepana, Wanisch, Klaus, Grillo, Federico W., Slaviero, Anna, Langley, Sarah R.

, Shkura, Kirill, Roncon, Paolo, De, Tisham, Mattheisen, Manuel, Niehusmann, Pitt, O’Brien, Terence J., Petrovski, Slave, von Lehe, Marec, Hoffmann, Per, Eriksson, Johan, Coffey, Alison J., Cichon, Sven, Walker, Matthew, Simonato, Michele, Danis, Bénédicte, Mazzuferi, Manuela, Foerch, Patrik, Schoch, Susanne, De Paola, Vincenzo, Kaminski, Rafal M., Cunliffe, Vincent T., Becker, Albert J. and Petretto, Enrico 2015. Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus. Nature Communications 6 , 6031. 10.1038/ncomms7031

Johnson, Michelle D., Mueller, Michael, Adamowicz-Brice, Martyna, Collins, Melissa J., Gellert, Pascal, Maratou, Klio, Srivastava, Prashant K., Rotival, Maxime, Butt, Shahena, Game, Laurence, Atanur, Santosh S., Silver, Nicholas, Norsworthy, Penny J., Langley, Sarah R.

, Petretto, Enrico, Pravenec, Michal and Aitman, Timothy J. 2014. Genetic analysis of the cardiac methylome at single nucleotide resolution in a model of human cardiovascular disease. Plos Genetics 10 (12) , e1004813. 10.1371/journal.pgen.1004813

Cuello, Friederike, Shankar-Hari, Manu, Mayr, Ursula, Yin, Xiaoke, Marshall, Melanie, Suna, Gonca, Willeit, Peter, Langley, Sarah R.

, Jayawardhana, Tamani, Zeller, Tanja, Terblanche, Marius, Shah, Ajay M. and Mayr, Manuel 2014. Redox state of pentraxin 3 as a novel biomarker for resolution of inflammation and survival in sepsis. Molecular & cellular proteomics : MCP 13 (10) , pp. 2545-2557. 10.1074/mcp.M114.039446

Zampetaki, Anna, Attia, Rizwan, Mayr, Ursula, Gomes, Renata S.M., Phinikaridou, Alkystis, Yin, Xiaoke, Langley, Sarah R.

, Willeit, Peter, Lu, Ruifang, Fanshawe, Bruce, Fava, Marika, Barallobre-Barreiro, Javier, Molenaar, Chris, So, Po-Wah, Abbas, Abeera, Jahangiri, Marjan, Waltham, Matthew, Botnar, Rene, Smith, Alberto and Mayr, Manuel 2014. Role of miR-195 in aortic aneurysmal disease. Circulation Research 115 (10) , pp. 857-866. 10.1161/circresaha.115.304361

Goedeke, Leigh, Salerno, Alessandro, Ramírez, Cristina M, Guo, Liang, Allen, Ryan M, Yin, Xiaoke, Langley, Sarah R

, Esau, Christine, Wanschel, Amarylis, Fisher, Edward A, Suarez, Yajaira, Baldán, Angel, Mayr, Manuel and Fernández-Hernando, Carlos 2014. Long-term therapeutic silencing of miR-33 increases circulating triglyceride levels and hepatic lipid accumulation in mice. EMBO Molecular Medicine 6 (9) , pp. 1133-1141. 10.15252/emmm.201404046

Stegemann, Christin, Pechlaner, Raimund, Willeit, Peter, Langley, Sarah R.

, Mangino, Massimo, Mayr, Ursula, Menni, Cristina, Moayyeri, Alireza, Santer, Peter, Rungger, Gregor, Spector, Tim D., Willeit, Johann, Kiechl, Stefan and Mayr, Manuel 2014. Lipidomics profiling and risk of cardiovascular disease in the prospective population-based Bruneck study. Circulation Research 129 (18) , pp. 1821-1831. 10.1161/circulationaha.113.002500

Beyer, Christian, Zampetaki, Anna, Lin, Neng-Yu, Kleyer, Arnd, Perricone, Carlo, Iagnocco, Annamaria, Distler, Alfiya, Langley, Sarah R.

, Gelse, Kolja, Sesselmann, Stefan, Lorenzini, Rolando, Niemeier, Andreas, Swoboda, Bernd, Distler, Jörg H. W., Santer, Peter, Egger, Georg, Willeit, Johann, Mayr, Manuel, Schett, Georg and Kiechl, Stefan 2014. Signature of circulating microRNAs in osteoarthritis. Annals of the Rheumatic Diseases 74 (3) 10.1136/annrheumdis-2013-204698

Abonnenc, Mélanie, Nabeebaccus, Adam A., Mayr, Ursula, Barallobre-Barreiro, Javier, Dong, Xuebin, Cuello, Friederike, Sur, Sumon, Drozdov, Ignat, Langley, Sarah R.

, Lu, Ruifang, Stathopoulou, Konstantina, Didangelos, Athanasios, Yin, Xiaoke, Zimmermann, Wolfram-Hubertus, Shah, Ajay M., Zampetaki, Anna and Mayr, Manuel 2013. Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c. Circulation Research 113 (10) , pp. 1138-1147. 10.1161/circresaha.113.302400

Langley, Sarah R.

, Bottolo, Leonardo, Kunes, Jaroslav, Zicha, Josef, Zidek, Vaclav, Hubner, Norbert, Cook, Stuart A., Pravenec, Michal, Aitman, Timothy J. and Petretto, Enrico 2013. Systems-level approaches reveal conservation of trans-regulated genes in the rat and genetic determinants of blood pressure in humans. Cardiovascular Research 97 (4) , pp. 653-665. 10.1093/cvr/cvs329

Langley, Sarah R.

, Dwyer, Joseph, Drozdov, Ignat, Yin, Xiaoke and Mayr, Manuel 2013. Proteomics: from single molecules to biological pathways. Cardiovascular Research 97 (4) , pp. 612-622. 10.1093/cvr/cvs346

Yin, Xiaoke, Dwyer, Joseph, Langley, Sarah R.

, Mayr, Ursula, Xing, Qiuru, Drozdov, Ignat, Nabeebaccus, Adam, Shah, Ajay M., Madhu, Basetti, Griffiths, John, Edwards, Lindsay M. and Mayr, Manuel 2013. Effects of perhexiline-induced fuel switch on the cardiac proteome and metabolome. Journal of Molecular and Cellular Cardiology 55 , pp. 27-30. 10.1016/j.yjmcc.2012.12.014

Stegemann, Christin, Didangelos, Athanasios, Barallobre-Barreiro, Javier, Langley, Sarah R.

, Mandal, Kaushik, Jahangiri, Marjan and Mayr, Manuel 2013. Proteomic identification of matrix metalloproteinase substrates in the human vasculature. Circulation. Cardiovascular genetics 6 (1) , pp. 106-117. 10.1161/circgenetics.112.964452

Willeit, Peter, Zampetaki, Anna, Dudek, Katarzyna, Kaudewitz, Dorothee, King, Alice, Kirkby, Nicholas S., Crosby-Nwaobi, Roxanne, Prokopi, Marianna, Drozdov, Ignat, Langley, Sarah R.

, Sivaprasad, Sobha, Markus, Hugh S., Mitchell, Jane A., Warner, Timothy D., Kiechl, Stefan and Mayr, Manuel 2013. Circulating microRNAs as novel biomarkers for platelet activation. Circulation Research 112 (4) , pp. 595-600. 10.1161/circresaha.111.300539

Lin, Bevan, Huntley, Derek, AbuAli, Ghada, Langley, Sarah R.

, Sindelar, George, Petretto, Enrico, Butcher, Sarah and Grimm, Stefan 2011. Determining signalling nodes for apoptosis by a genetic high-throughput screen. Plos One 6 (9) , e25023. 10.1371/journal.pone.0025023

Bottolo, Leonardo, Chadeau-Hyam, Marc, Hastie, David I., Langley, Sarah R.

, Petretto, Enrico, Tiret, Laurence, Tregouet, David and Richardson, Sylvia 2011. ESS++: a C++ objected-oriented algorithm for Bayesian stochastic search model exploration. Bioinformatics 27 (4) , pp. 587-588. 10.1093/bioinformatics/btq684

Heinig, Matthias, Petretto, Enrico, Wallace, Chris, Bottolo, Leonardo, Rotival, Maxime, Lu, Han, Li, Yoyo, Sarwar, Rizwan, Langley, Sarah R.

, Bauerfeind, Anja, Hummel, Oliver, Lee, Young-Ae, Paskas, Svetlana, Rintisch, Carola, Saar, Kathrin, Cooper, Jason, Buchan, Rachel, Gray, Elizabeth E., Cyster, Jason G., Erdmann, Jeanette, Hengstenberg, Christian, Maouche, Seraya, Ouwehand, Willem H., Rice, Catherine M., Samani, Nilesh J., Schunkert, Heribert, Goodall, Alison H., Schulz, Herbert, Roider, Helge G., Vingron, Martin, Blankenberg, Stefan, Münzel, Thomas, Zeller, Tanja, Szymczak, Silke, Ziegler, Andreas, Tiret, Laurence, Smyth, Deborah J., Pravenec, Michal, Aitman, Timothy J., Cambien, Francois, Clayton, David, Todd, John A., Hubner, Norbert and Cook, Stuart A. 2010. A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk. Nature 467 , pp. 460-464. 10.1038/nature09386

Petretto, Enrico, Bottolo, Leonardo, Langley, Sarah R.

, Heinig, Matthias, McDermott-Roe, Chris, Sarwar, Rizwan, Pravenec, Michal, Hubner, Norbert, Aitman, Timothy J., Cook, Stuart A. and Richardson, Sylvia 2010. New insights into the genetic control of gene expression using a Bayesian multi-tissue approach. PLoS Computational Biology 10.1371/journal.pcbi.1000737

Stylianou, Ioannis M., Langley, Sarah R.

, Walsh, Kenneth, Chen, Yuan, Revenu, Céline and Paigen, Beverly 2008. Differences in DBA/1J and DBA/2J reveal lipid QTL genes. Journal of Lipid Research 49 (11) , pp. 2402-2413. 10.1194/jlr.M800244-JLR200

This list was generated on Sat Nov 8 12:30:13 2025 GMT.