Pisanò, Clarissa A., Mercatelli, Daniella, Mazzocchi, Martina, Brugnoli, Alberto, Morella, Ilaria ORCID: https://orcid.org/0000-0001-5691-5400, Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139, Zaveri, Nurulain T., Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706, O'Keeffe, Gerard W., Neubig, Richard R. and Morari, Michele 2023. Regulator of G-Protein Signalling 4 (RGS4) negatively modulates nociceptin/orphanin FQ opioid receptor signalling: Implication for l-Dopa-induced dyskinesia. British Journal of Pharmacology 180 (7) , pp. 927-942. 10.1111/bph.15730 |
Bernardi, Rick E., Olevska, Anastasia, Morella, Ilaria ORCID: https://orcid.org/0000-0001-5691-5400, Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139, Santos, Eugenio, Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706 and Spanagel, Rainer 2019. The inhibition of RasGRF2, but not RasGRF1, alters cocaine reward in mice. Journal of Neuroscience 39 (32) , pp. 6325-6338. 10.1523/JNEUROSCI.1120-18.2019 |
Ruiz De Diego, Irene, Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139, Solis, Oscar, Garcia-Montes, Jose-Ruben, Brea, Jose, Loza, Maria, Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706 and Rosario, Moratalla 2018. Genetic enhancement of Ras-ERK pathway does not aggravate L-DOPA-induced dyskinesia in mice but prevents the decrease induced by lovastatin. Scientific Reports 8 , 15381. 10.1038/s41598-018-33713-3 |
Arcuri, Ludovico, Novello, Salvatore, Frassineti, Martina, Mercatelli, Daniela, Pisano, Clarissa Anna, Morella, Ilaria ORCID: https://orcid.org/0000-0001-5691-5400, Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139, Journigan, Blair V., Meyer, Michael E., Polgar, Willma E., Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706, Zaveri, Nurulain T. and Morari, Michele 2018. Anti-parkinsonian and anti-dyskinetic profiles of two novel potent and selective nociceptin/orphanin FQ receptor agonists. British Journal of Pharmacology 175 (5) , pp. 782-796. 10.1111/bph.14123 |
Papale, Alessandro ORCID: https://orcid.org/0000-0002-8794-0171, d'Isa, Raffaele, Menna, Elisabetta, Cerovic, Milica, Solari, Nicola, Hardingham, Neil, Cambiaghi, Marco, Cursi, Marco, Barbacid, Mariano, Leocani, Letizia, Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139, Matteoli, Michela and Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706 2017. Severe intellectual disability and enhanced gamma-aminobutyric acidergic synaptogenesis in a novel model of rare RASopathies. Biological Psychiatry 81 (3) , pp. 179-192. 10.1016/j.biopsych.2016.06.016 |
Papale, Alessandro ORCID: https://orcid.org/0000-0002-8794-0171, Morella, Ilaria Maria ORCID: https://orcid.org/0000-0001-5691-5400, Indrigo, Marzia Tina, Bernardi, Rick Eugene, Marrone, Livia, Marchisella, Francesca, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Spanagel, Rainer, Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706 and Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139 2016. Impairment of cocaine-mediated behaviours in mice by clinically relevant Ras-ERK inhibitors. eLife 5 , e17111. 10.7554/eLife.17111 |
Bastide, Matthieu F., Meissner, Wassilios G., Picconi, Barbara, Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139, Fernagut, Pierre-Olivier, Feyder, Michael, Francardo, Veronica, Alcacer, Cristina, Ding, Yunmin, Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706, Fisone, Gilberto, Jon Stoessl, A., Bourdenx, Mathieu, Engeln, Michel, Navailles, Sylvia, De Deurwaerdère, Philippe, Ko, Wai Kin D., Simola, Nicola, Morelli, Micaela, Groc, Laurent, Rodriguez, Maria-Cruz, Gurevich, Eugenia V., Quik, Maryka, Morari, Michele, Mellone, Manuela, Gardoni, Fabrizio and Tronci, Elisabetta 2015. Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease. Progress in Neurobiology 132 , pp. 96-168. 10.1016/j.pneurobio.2015.07.002 |
Bido, Simone, Solari, Nicola, Indrigo, Marzia, D'Antoni, Angela, Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706, Morari, Michele and Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139 2015. Differential involvement of Ras-GRF1 and Ras-GRF2 in L-DOPA-induced dyskinesia. Annals of Clinical and Translational Neurology 2 (6) , pp. 662-678. 10.1002/acn3.202 |
Cerovic, Milica, Bagetta, Vincenza, Pendolino, Valentina, Ghiglieri, Veronica, Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139, Morella, Ilaria ORCID: https://orcid.org/0000-0001-5691-5400, Hardingham, Neil, Heuer, Andreas ORCID: https://orcid.org/0000-0003-0300-7606, Papale, Alessandro ORCID: https://orcid.org/0000-0002-8794-0171, Marchisella, Francesca, Giampà, Carmela, Calabresi, Paolo, Picconi, Barbara and Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706 2015. Derangement of Ras-guanine nucleotide-releasing Factor 1 (Ras-GRF1) and extracellular signal-regulated kinase (ERK) dependent striatal plasticity in L-DOPA-induced dyskinesia. Biological Psychiatry 77 (2) , pp. 106-115. 10.1016/j.biopsych.2014.04.002 |
D'Isa, Raffaele, Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706 and Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139 2014. Behavioral methods for the study of the Ras-ERK pathway in memory formation and consolidation: passive avoidance and novel object recognition tests. Trabalzini, Lorenza and Retta, Saverio Francesco, eds. Ras Signaling: Methods and Protocols, Vol. 1120. Methods in Molecular Biology, Humana Press, pp. 131-156. (10.1007/978-1-62703-791-4_9) |
Marti, Matteo, Rodi, Donata, Li, Qin, Guerrini, Remo, Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139, Morella, Ilaria, Tozzi, Alessandro, Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706, Calabresi, Paolo, Simonato, Michele, Bezard, Erwan and Morari, Michele 2012. Nociceptin/orphanin FQ receptor agonists attenuate L-DOPA-induced dyskinesias. Journal of Neuroscience 32 (46) , pp. 16106-16119. 10.1523/JNEUROSCI.6408-11.2012 |
Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139 and Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706 2011. Ras-ERK signaling in behavior: old questions and new perspectives. Frontiers in Behavioral Neuroscience 5 (79) , pp. 1-6. 10.3389/fnbeh.2011.00079 |
d’Isa, Raffaele, Clapcote, Steven, Voikar, Vootele, Wolfer, David, Giese, Karl Peter, Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706 and Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139 2011. Mice lacking Ras-GRF1 show contextual fear conditioning but not spatial memory impairments: convergent evidence from two independently generated mouse mutant lines. Frontiers in Behavioral Neuroscience 5 (78) , pp. 1-11. |
Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139, Bezard, E., D'Antoni, A., Francardo, V., Indrigo, M., Qin, L., Dovero, S., Cerovic, Milica, Cenci, M. A. and Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706 2010. Inhibition of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) signaling in the striatum reverts motor symptoms associated with L-dopa-induced dyskinesia. Proceedings of the National Academy of Sciences 107 (50) , pp. 21824-21829. 10.1073/pnas.1012071107 |
Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139, D'Antoni, A., Orban, P. C., Valjent, E., Putignano, E., Vara, H., Pizzorusso, T., Giustetto, M., Yoon, B., Soloway, P., Maldonado, R., Caboche, J. and Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706 2009. Ras-Guanine Nucleotide-Releasing Factor 1 (Ras-GRF1) controls activation of Extracellular Signal-Regulated Kinase (ERK) signaling in the striatum and long-term behavioral responses to cocaine. Biological Psychiatry 66 (8) , pp. 758-768. 10.1016/j.biopsych.2009.03.014 |
Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139, Pittenger, Christopher and Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706 2009. Inhibition of CREB activity in the dorsal portion of the striatum potentiates behavioral responses to drugs of abuse. Frontiers in Behavioral Neuroscience 3 , 29. 10.3389/neuro.08.029.2009 |
Givogri, M. I., Bottai, D., Zhu, H. L., Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139, Lamorte, G., Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706, Vescovi, A., Wrabetz, L. and Bongarzone, E. 2008. Multipotential Neural Precursors Transplanted into the Metachromatic Leukodystrophy Brain Fail to Generate Oligodendrocytes but Contribute to Limit Brain Dysfunction. Developmental Neuroscience 30 , pp. 340-357. 10.1159/000150127 |
Capotondo, A., Cesani, M., Pepe, S., Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139, Gregori, S., Tononi, L., Venneri, M.A., Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706, Quattrini, A., Ballabio, A., Cosma, M. P., Naldini, L. and Biffi, A. 2007. Safety of Arylsulfatase A overexpression for gene therapy of metachromatic leukodystrophy. Human Gene Therapy 18 (9) , pp. 821-836. 10.1089/hum.2007.048 |
Ferguson, Susan M., Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139, Yang, Pengwei, Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706 and Robinson, Terry E. 2006. Knockout of ERK1 enhances cocaine-evoked immediate early gene expression and behavioral plasticity. Neuropsychopharmacology , pp. 2660-2668. 10.1038/sj.npp.1301014 |
Biffi, Alessandra, Capotondo, Alessia, Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139, del Carro, Ubaldo, Marchesini, Sergio, Azuma, Hisaya, Malaguti, Maria Chiara, Amadio, Stefano, Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706, Grompe, Markus, Bordignon, Claudio, Quattrini, Angelo and Naldini, Luigi 2006. Gene therapy of metachromatic leukodystrophy reverses neurological damage and deficits in mice. The Journal of Clinical Investigation 116 (11) , pp. 3070-3082. 10.1172/JCI28873 |
Pittenger, Christopher, Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139, Mazzocchi-Jones, David Martin, Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578, Kandel, Eric R. and Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706 2006. Impaired bidirectional synaptic plasticity and procedural memory formation in striatum-specific cAMP response element-binding protein-deficient mice. Journal of Neuroscience 26 (10) , pp. 2808-2813. 10.1523/JNEUROSCI.5406-05.2006 |
Givogri, M. I., Galbiati, F., Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139, Amadio, S., Perani, L., Superchi, D., Morana, P., Del Carro, U., Marchesini, S., Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706, Wrabetz, L. and Bongarzone, E. 2006. Oligodendroglial progenitor cell therapy limits central neurological deficits in mice with metachromatic leukodystrophy. Journal of Neuroscience 26 (12) , pp. 3109-3199. 10.1523/JNEUROSCI.4366-05.2006 |
Croci, C., Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139, Superchi, D., Perani, L., Martellosio, A., Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706, Consalez, G. and Bongarzone, E. R. 2006. Cerebellar neurons and glial cells are transducible by lentiviral vectors without decrease of cerebellar functions. Developmental Neuroscience 28 (3) , pp. 216-222. 10.1159/000091919 |
Mazzuccchelli, Cristina, Vantaggiato, Chiara, Ciamei, Alessandro, Fasano, Stefania ORCID: https://orcid.org/0000-0002-3696-7139, Pakhotin, Pavel, Krezel, Wojciech, Welzl, Hans, Wolfer, David P., Pages, Gilles, Valverde, Olga, Marowsky, Anne, Porrazzo, Annamaria, Orban, Paul C., Maldonado, Rafael, Ehrengruber, Markus U.Anne, Cestari, Vincenzo, Lipp, Hans-Peter, Chapman, Paul Frederick James, Pouyssegur, Jacques and Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706 2002. Knockout of ERK1 MAP Kinase enhances synaptic plasticity in the striatum and facilitates striatal-mediated learning and memory. Neuron , pp. 807-820. 10.1016/S0896-6273(02)00716-X |
Fasano, Stephania ORCID: https://orcid.org/0000-0002-3696-7139 and Brambilla, Riccardo ORCID: https://orcid.org/0000-0003-3569-5706 2002. Cellular mechanisms of striatum-dependent behavioral plasticity and drug addiction. Current Molecular Medicine 2 (7) , pp. 649-665. 10.2174/1566524023362005 |