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Number of items: 12.

Baldwin, Alex G. ORCID: https://orcid.org/0000-0002-7126-5220, Foley, David W. ORCID: https://orcid.org/0000-0001-8449-4754, Collins, Ross, Lee, Hyunah, Jones, D. Heulyn, Wahab, Ben, Waters, Loren, Pedder, Josephine, Paine, Marie, Feng, Gui Jie, Privitera, Lucia, Ashall-Kelly, Alexander, Thomas, Carys, Gillespie, Jason A., Schino, Lauramariú, Belelli, Delia, Rocha, Cecilia, Maussion, Gilles, Krahn, Andrea I., Durcan, Thomas M., Elkins, Jonathan M., Lambert, Jeremy J., Atack, John R. ORCID: https://orcid.org/0000-0002-3410-791X and Ward, Simon E. ORCID: https://orcid.org/0000-0002-8745-8377 2025. Discovery of MDI-114215: A potent and selective LIMK inhibitor to treat fragile X syndrome. Journal of Medicinal Chemistry 68 (1) , pp. 719-752. 10.1021/acs.jmedchem.4c02694
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University College Cardiff Consultants Limited 2022. Heteroaryl compounds useful in the treatment of cognitive disorders. WO2022/234271. [Patent].
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Collins, Ross, Lee, Hyunah, Jones, Dyfyr, Elkins, Jonathan M., Gillespie, Jason A., Thomas, Carys, Baldwin, Alex G. ORCID: https://orcid.org/0000-0002-7126-5220, Jones, Kimberley, Waters, Loren, Paine, Marie, Atack, John R. ORCID: https://orcid.org/0000-0002-3410-791X, Ward, Simon E. ORCID: https://orcid.org/0000-0002-8745-8377, Grubisha, Olivera ORCID: https://orcid.org/0000-0003-1067-1230 and Foley, David W. ORCID: https://orcid.org/0000-0001-8449-4754 2022. Comparative analysis of small-molecule limk1/2 inhibitors: chemical synthesis, biochemistry, and cellular activity. Journal of Medicinal Chemistry 10.1021/acs.jmedchem.2c00751
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University of Manchester 2020. Cyclic diarylboron derivatives as NLRP3 inflammasome inhibitors. US 10570157. [Patent].
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Alnabulsi, Soraya, Hussein, Buthaina, Santina, Elham, Alsalahat, Izzeddin, Kadirvel, Manikandan, Magwaza, Rachael N., Bryce, Richard A., Schwalbe, Carl H., Baldwin, Alex ORCID: https://orcid.org/0000-0002-7126-5220, Russo, Ilaria, Stratford, Ian J. and Freeman, Sally 2018. Evaluation of analogues of furan-amidines as inhibitors of NQO2. Biorganic and Medicinal Chemistry Letters 28 (8) , pp. 1292-1297. 10.1016/j.bmcl.2018.03.025
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Redondo-Castro, Elena, Faust, Dorte, Fox, Simon, Baldwin, Alex G. ORCID: https://orcid.org/0000-0002-7126-5220, Osborne, Simon, Haley, Michael J., Karran, Eric, Nuthall, Hugh, Atkinson, Peter J., Dawson, Lee A., Routledge, Carol, Allan, Stuart M., Freeman, Sally, Brownlees, Janet and Brough, David 2018. Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent responses. Scientific Reports 8 (1) , 5667. 10.1038/s41598-018-24029-3
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Baldwin, Alex ORCID: https://orcid.org/0000-0002-7126-5220, Bevan, Jonathan, Brough, David, Ledder, Ruth and Freeman, Sally 2018. Synthesis and antibacterial activities of enamine derivatives of dehydroacetic acid. Medicinal Chemistry Research 27 (3) , pp. 884-889. 10.1007/s00044-017-2110-8
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Baldwin, Alex ORCID: https://orcid.org/0000-0002-7126-5220, Tapia, Victor S., Swanton, Tessa, White, Claire S., Beswick, James A., Brough, David and Freeman, Sally 2018. Design, synthesis and evaluation of oxazaborine inhibitors of the NLRP3 inflammasome. ChemMedChem 13 (4) , pp. 312-320. 10.1002/cmdc.201700731
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Baldwin, Alex ORCID: https://orcid.org/0000-0002-7126-5220, Rivers-Auty, Jack, Daniels, Michael J.D., White, Claire S., Schwalbe, Carl H., Schilling, Tom, Hammadi, Halah, Jaiyong, Panichakorn, Spencer, Nicholas G., England, Hazel, Luheshi, Nadia M., Kadirvel, Manikandan, Lawrence, Catherine B., Rothwell, Nancy J., Harte, Michael K., Bryce, Richard A., Allan, Stuart M., Eder, Claudia, Freeman, Sally and Brough, David 2017. Boron-based inhibitors of the NLRP3 inflammasome. Cell Chemical Biology 24 (11) , pp. 1321-1335. 10.1016/j.chembiol.2017.08.011
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University of Manchester 2017. Cyclic diarylboron derivatives as NLRP3 inflammasome inhibitors. WO/2017/017469. [Patent].

Daniels, Michael J. D., Rivers-Auty, Jack, Schilling, Tom, Spencer, Nicholas G., Watremez, William, Fasolino, Victoria, Booth, Sophie J., White, Claire S., Baldwin, Alex ORCID: https://orcid.org/0000-0002-7126-5220, Freeman, Sally, Wong, Raymond, Latta, Clare, Yu, Shi, Jackson, Joshua, Fischer, Nicolas, Koziel, Violette, Pillot, Thierry, Bagnall, James, Allan, Stuart M., Paszek, Pawel, Galea, James, Harte, Michael K., Eder, Claudia, Lawrence, Catherine B. and Brough, David 2016. Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models. Nature Communications 7 , 12504. 10.1038/ncomms12504
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Baldwin, Alex ORCID: https://orcid.org/0000-0002-7126-5220, Brough, David and Freeman, Sally 2015. Inhibiting the inflammasome: a chemical perspective. Journal of Medicinal Chemistry 59 (5) , pp. 1691-1710. 10.1021/acs.jmedchem.5b01091

This list was generated on Sun Jan 19 05:36:14 2025 GMT.


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