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Browse by Current Cardiff authors

Number of items: 21.

Thomas, Bedwyr, Lewis, Lois, Jones, Dyfyr and Ward, Simon ORCID: 2023. Central nervous system targeted protein degraders. Biomolecules 13 (8) , 1164. 10.3390/biom13081164

Davies, Mari, Riseley, Ross, Jones, Dyfyr H. and Waller-Evans, Helen ORCID: 2023. Acid ceramidase inhibition as a mechanism to treat lysosomal disorders. Molecular Genetics and Metabolism 138 (2) , 107069. 10.1016/j.ymgme.2022.107069

Collins, Ross, Lee, Hyunah, Jones, Dyfyr, Elkins, Jonathan M., Gillespie, Jason A., Thomas, Carys, Baldwin, Alex G. ORCID:, Jones, Kimberley, Waters, Loren, Paine, Marie, Atack, John R. ORCID:, Ward, Simon E. ORCID:, Grubisha, Olivera ORCID: and Foley, David W. ORCID: 2022. Comparative analysis of small-molecule limk1/2 inhibitors: chemical synthesis, biochemistry, and cellular activity. Journal of Medicinal Chemistry 10.1021/acs.jmedchem.2c00751

Romartinez-Alonso, Beatriz, Agostini, Maura, Jones, Heulyn, McLellan, Jayde, Sood, Deepali, Tomkinson, Nicholas, Marelli, Federica, Gentile, Ilaria, Visser, W. Edward, Schoenmakers, Erik, Fairall, Louise, Privalsky, Martin, Moran, Carla, Persani, Luca, Chatterjee, Krishna and Schwabe, John 2022. Structure-guided approach to relieving transcriptional repression inResistance to Thyroid Hormone α. Molecular and Cellular Biology 42 (2) , e00363-21. 10.1128/MCB.00363-21

Fromont, Christophe, Atzori, Alessio, Kaur, Divneet, Hashmi, Lubna, Greco, Graziella, Cabanillas, Alejandro, Nguyen, Huy Van, Jones, D. Heulyn, Garzón, Miguel, Varela, Ana, Stevenson, Brett, Iacobini, Greg, Lenoir, Marc, Rajesh, Sundaresan, Box, Clare, Kumar, Jitendra, Grant, Paige, Novitskaia, Vera, Morgan, Juliet, Sorrell, Fiona, Redondo, Clara, Kramer, Andreas, Harris, C. John, Leighton, Brendan, Vickers, Steven, Cheetham, Sharon, Kenyon, Colin, Grabowska, Anna M., Overduin, Michael, Berditchevski, Fedor, Weston, Chris J, Knapp, Stefan, Fischer, Peter M. and Butterworth, Sam 2020. Discovery of highly selective inhibitors of calmodulin-dependent kinases that restore insulin sensitivity in the diet-induced obese in vivo mouse model. Journal of Medicinal Chemistry 63 (13) , pp. 6784-6801. 10.1021/acs.jmedchem.9b01803

Radhi, Ohood A., Davidson, Scott, Scott, Fiona, Zeng, Run X., Jones, D. Heulyn, Tomkinson, Nicholas C. O., Yu, Jun and Chan, Edmond Y. W. 2019. Inhibition of the ULK1 protein complex suppresses Staphylococcus-induced autophagy and cell death. Journal of Biological Chemistry 294 (39) , pp. 14289-14307. 10.1074/jbc.RA119.008923

Pariollaud, Marie, Gibbs, Julie E., Hopwood, Thomas W., Brown, Sheila, Begley, Nicola, Vonslow, Ryan, Poolman, Toryn, Guo, Baoqiang, Saer, Ben, Jones, D. Heulyn, Tellam, James P., Bresciani, Stefano, Tomkinson, Nicholas C.O., Wojno-Picon, Justyna, Cooper, Anthony W.J., Daniels, Dion A., Trump, Ryan P., Grant, Daniel, Zuercher, William, Willson, Timothy M., MacDonald, Andrew S., Bolognese, Brian, Podolin, Patricia L., Sanchez, Yolanda, Loudon, Andrew S.I. and Ray, David W. 2018. Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation. Journal of Clinical Investigation 128 (6) , pp. 2281-2296. 10.1172/JCI93910

Frei, Przemyslaw, Jones, D. Heulyn, Kay, Steven T., McLellan, Jayde A., Johnston, Blair F., Kennedy, Alan R. and Tomkinson, Nicholas C. O. 2018. Regioselective reaction of heterocyclic N-oxides, an acyl chloride, and cyclic thioethers. Journal of Organic Chemistry 83 (3) , pp. 1510-1517. 10.1021/acs.joc.7b02457

Jones, D. Heulyn, Kay, Steven T., McLellan, Jayde A., Kennedy, Alan R. and Tomkinson, Nicholas C. O. 2017. Regioselective three-component reaction of pyridine N-oxides, acyl chlorides, and cyclic ethers. Organic Letters 19 (13) , pp. 3512-3515. 10.1021/acs.orglett.7b01481

Jones, D. Heylyn, Tellam, James, Bresciani, Stefano, Wojno-Picon, Justyna, Cooper, Anthony and Tomkinson, Nicholas 2016. Preparation of symmetrical and nonsymmetrical fluorene ­sulfonamide scaffolds. SYNLETT 28 (05) , pp. 577-582. 10.1055/s-0036-1588916

Saleh, Basil A., Smith, Keith, Elliott, Mark Christopher ORCID:, Jones, Dyfyr Heulyn, Kariuki, Benson M. ORCID: and El Hiti, Gamal A. 2016. Reactions of organoboranes with carbanions bearing three potential leaving groups: unusual processes, products and mechanisms. Tetrahedron 72 (44) , pp. 6914-6928. 10.1016/j.tet.2016.09.005

Dragan, Andrei, Jones, D. Heulyn, Kennedy, Alan R. and Tomkinson, Nicholas C. O. 2016. Stereoselective synthesis of alkylidene phthalides. Organic Letters 18 (13) , pp. 3086-3089. 10.1021/acs.orglett.6b01203

Jones, D. Heulyn, Bresciani, Stefano, Tellam, James P., Wojno, Justyna, Cooper, Anthony W. J., Kennedy, Alan R. and Tomkinson, Nicholas C. O. 2016. Synthesis of dibenzylamino-1-methylcyclohexanol and dibenzylamino-1-trifluoromethylcyclohexanol isomers. Organic and Biomolecular Chemistry 14 (1) , pp. 172-182. 10.1039/C5OB01924A

Jones, Dyfyr Heulen, Smith, Keith, Elliott, Mark Christopher ORCID: and El-Hiti, Gamal A. 2015. Factors affecting reactions of trialkylcyanoborates with imidoyl chlorides/trifluoroacetic anhydride. Tetrahedron 71 (36) , pp. 6285-6289. 10.1016/j.tet.2015.06.038

El-Hiti, Gamal A., Smith, Keith, Hegazy, Amany S., Jones, D. Heulyn and Kariuki, Benson ORCID: 2014. 2-Ethyl-3-[(R)-2-phenylbutanamido]quinazolin-4(3H)-one monohydrate. Acta Crystallographica Section E - Structure Reports Online 70 (4) , o467. 10.1107/S1600536814005996

Elliott, Mark Christopher ORCID: and Jones, Dyfyr Heulyn 2014. [4 + 2] Cycloaddition as the key step. Muller, T. J. J., ed. Multicomponent Reactions 2. Reactions Involving an a,b-Unsaturated Carbonyl Compound as Electrophilic Component, Cycloadditions, and Boron-, Silicon-, Free-Radical-, and Metal-Mediated Reactions, Düsseldorf: Thieme, pp. 243-286.

El-Hiti, Gamal A., Smith, Keith, Elliott, Mark Christopher ORCID:, Jones, Dyfyr Heulyn and Kariuki, Benson ORCID: 2013. (E)-2-(1,1-Dicyclohexyl-3-phenylallyl)-5,5-dimethyl-1,3,2-dioxaborinane. Acta Crystallographica Section E - Structure Reports Online 69 (9) , o1403. 10.1107/S1600536813021739

El-Hiti, Gamal A., Smith, Keith, Jones, Dyfyr Heulyn, Masmali, Ali and Kariuki, Benson M. ORCID: 2013. (Z)-N-(2,6-Diisopropylphenyl)-4-nitrobenzimidoyl chloride. Acta Crystallographica Section E 69 (9) , o1384. 10.1107/S1600536813020862

Jones, Dyfyr Heulyn 2013. Approaches to quaternary carbon centres using organoboron chemistry. PhD Thesis, Cardiff University.
Item availability restricted.

Elliott, Mark Christopher ORCID:, Smith, Keith, Jones, Dyfyr Heulyn, Hussain, Aja and Saleh, Basil A. 2013. Factors affecting migration of tertiary alkyl groups in reactions of alkylboronic esters with bromomethyllithium. The Journal of Organic Chemistry 78 (7) , pp. 3057-3064. 10.1021/jo4000459

Smith, Keith, Elliott, Mark Christopher ORCID: and Jones, Dyfyr Heulyn 2013. 3-Chloro-1-lithiopropene - a functional organolithium reagent - and its reactions with alkylboronates to give 3-Alkylprop-1-en-3-ols. Journal of Organic Chemistry 78 (18) , pp. 9526-9531. 10.1021/jo4018028

This list was generated on Wed May 29 05:07:55 2024 BST.