Ng, Bryan, Vowles, Jane, Bertherat, Féodora, Abey, Ajantha, Kilfeather, Peter, Beccano-Kelly, Dayne ORCID: https://orcid.org/0000-0003-3592-8354, Stefana, M. Irina, O'Brien, Darragh P., Bengoa-Vergniory, Nora, Carling, Phillippa J., Todd, John A., Caffrey, Tara M., Connor-Robson, Natalie, Cowley, Sally A. and Wade-Martins, Richard 2024. Tau depletion in human neurons mitigates Aβ-driven toxicity. Molecular Psychiatry 29 , pp. 2009-2020. 10.1038/s41380-024-02463-2 |
Beccano-Kelly, Dayne A. ORCID: https://orcid.org/0000-0003-3592-8354, Cherubini, Marta, Mousba, Yassine, Cramb, Kaitlyn M.L., Giussani, Stefania, Caiazza, Maria Claudia, Rai, Pavandeep, Vingill, Siv, Bengoa-Vergniory, Nora, Ng, Bryan, Corda, Gabriele, Banerjee, Abhirup, Vowles, Jane, Cowley, Sally and Wade-Martins, Richard 2023. Calcium dysregulation combined with mitochondrial failure and electrophysiological maturity converge in Parkinson’s iPSC-dopamine neurons. iScience 26 (7) , 107044. 10.1016/j.isci.2023.107044 |
Burley, Sarah, Beccano-Kelly, Dayne A. ORCID: https://orcid.org/0000-0003-3592-8354, Talbot, Kevin, Llana, Oscar Cordero and Wade-Martins, Richard 2022. Hyperexcitability in young iPSC-derived C9ORF72 mutant motor neurons is associated with increased intracellular calcium release. Scientific Reports 12 (1) , 7378. 10.1038/s41598-022-09751-3 |
Mancini, Andrea, Mazzocchetti, Petra, Sciaccaluga, Miriam, Megaro, Alfredo, Bellingacci, Laura, Beccano-Kelly, Dayne A. ORCID: https://orcid.org/0000-0003-3592-8354, Di Filippo, Massimiliano, Tozzi, Alessandro and Calabresi, Paolo 2020. From synaptic dysfunction to neuroprotective strategies in genetic Parkinson’s disease: lessons from LRRK2. Frontiers in Cellular Neuroscience 14 10.3389/fncel.2020.00158 |
Überbacher, Christa, Obergasteiger, Julia, Volta, Mattia, Venezia, Serena, Müller, Stefan, Pesce, Isabella, Pizzi, Sara, Lamonaca, Giulia, Picard, Anne, Cattelan, Giada, Malpeli, Giorgio, Zoli, Michele, Beccano-Kelly, Dayne ORCID: https://orcid.org/0000-0003-3592-8354, Flynn, Rowan, Wade-Martins, Richard, Pramstaller, Peter P, Hicks, Andrew A, Cowley, Sally A and Corti, Corrado 2019. Application of CRISPR/Cas9 editing and digital droplet PCR in human iPSCs to generate novel knock-in reporter lines to visualize dopaminergic neurons. Stem Cell Research 41 10.1016/j.scr.2019.101656 |
Benkert, Julia, Hess, Simon, Roy, Shoumik, Beccano-Kelly, Dayne A. ORCID: https://orcid.org/0000-0003-3592-8354, Wiederspohn, Nicole, Duda, Johanna, Simons, Carsten, Patil, Komal, Gaifullina, Aisylu, Mannal, Nadja, Dragicevic, Elena, Spaich, Desirée, Müller, Sonja, Nemeth, Julia, Hollmann, Helene, Deuter, Nora, Mousba, Yassine, Kubisch, Christian, Poetschke, Christina, Striessnig, Joerg, Pongs, Olaf, Schneider, Toni, Wade-Martins, Richard, Patel, Sandip, Parlato, Rosanna, Frank, Tobias, Kloppenburg, Peter and Liss, Birgit 2019. Cav2.3 channels contribute to dopaminergic neuron loss in a model of Parkinson’s disease. Nature Communications 10 (1) 10.1038/s41467-019-12834-x |
Volta, M, Cataldi, S, Beccano-Kelly, D ORCID: https://orcid.org/0000-0003-3592-8354, Munsie, L, Tatarnikov, I, Chou, P, Bergeron, S, Mitchell, E, Lim, R, Khinda, J, Lloret, A, Bennett, C F, Paradiso, C, Morari, M, Farrer, M J and Milnerwood, A J 2015. Chronic and acute LRRK2 silencing has no long-term behavioral effects, whereas wild-type and mutant LRRK2 overexpression induce motor and cognitive deficits and altered regulation of dopamine release. Parkinsonism & Related Disorders 21 (10) , pp. 1156-1163. 10.1016/j.parkreldis.2015.07.025 |
Munsie, L N, Milnerwood, A J, Seibler, P, Beccano-Kelly, D A ORCID: https://orcid.org/0000-0003-3592-8354, Tatarnikov, I, Khinda, J, Volta, M, Kadgien, C, Cao, L P, Tapia, L, Klein, C and Farrer, M J 2014. Retromer-dependent neurotransmitter receptor trafficking to synapses is altered by the Parkinson's disease VPS35 mutation p.D620N. Human Molecular Genetics 24 (6) , pp. 1691-1703. 10.1093/hmg/ddu582 |
Beccano-Kelly, D A ORCID: https://orcid.org/0000-0003-3592-8354, Volta, M, Munsie, L N, Paschall, S A, Tatarnikov, I, Co, K, Chou, P, Cao, L P, Bergeron, S, Mitchell, E, Han, H, Melrose, H L, Tapia, L, Raymond, L A, Farrer, M J and Milnerwood, A J 2014. LRRK2 overexpression alters glutamatergic presynaptic plasticity, striatal dopamine tone, postsynaptic signal transduction, motor activity and memory. Human Molecular Genetics 24 (5) , pp. 1336-1349. 10.1093/hmg/ddu543 |
Beccano-Kelly, D A ORCID: https://orcid.org/0000-0003-3592-8354, Kuhlmann, N, Tatarnikov, I, Volta, M, Munsie, L N, Chou, P, Cao, L P, Han, H, Tapia, L, Farrer, M J and Milnerwood, A J 2014. Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice. Frontiers in Cellular Neuroscience 10.3389/fncel.2014.00301 |
Vilarino-Guell, C, Rajput, A, Milnerwood, A J, Shah, B, Szu-Tu, C, Trinh, J, Yu, I, Encarnacion, M, Munsie, L N, Tapia, L, Gustavsson, E K, Chou, P, Tatarnikov, I, Evans, D M, Pishotta, F T, Volta, M, Beccano-Kelly, D ORCID: https://orcid.org/0000-0003-3592-8354, Thompson, C, Lin, M K, Sherman, H E, Han, H J, Guenther, B L, Wasserman, W W, Bernard, V, Ross, C J, Appel-Cresswell, S, Stoessl, A J, Robinson, C A, Dickson, D W, Ross, O A, Wszolek, Z K, Aasly, J O, Wu, R M, Hentati, F, Gibson, R A, McPherson, P S, Girard, M, Rajput, M, Rajput, A H and Farrer, M J 2014. DNAJC13 mutations in Parkinson disease. Human Molecular Genetics 23 (7) , pp. 1794-1801. 10.1093/hmg/ddt570 |
Brigidi, G S, Sun, Y, Beccano-Kelly, D ORCID: https://orcid.org/0000-0003-3592-8354, Pitman, K, Mobasser, M, Borgland, S L, Milnerwood, A J and Bamji, S X 2014. Palmitoylation of δ-catenin by DHHC5 mediates activity-induced synapse plasticity. Nature Neuroscience 17 (4) , pp. 522-532. 10.1038/nn.3657 |
Walker, Matthew D., Volta, Mattia, Cataldi, Stefano, Dinelle, Katherine, Beccano-Kelly, Dayne A. ORCID: https://orcid.org/0000-0003-3592-8354, Munsie, Lise, Kornelsen, Rick, Mah, Chenoa, Chou, Patrick, Co, Kimberley, Khinda, Jaskaran, Mroczek, Marta, Bergeron, Sabrina, Yu, Katrina, Cao, Li Ping, Funk, Nataljar, Ott, Thomas, Galter, Dagmar, Riess, Olaf, Biskup, Saskia, Milnerwood, Austen J., Stoessl, A. Jon, Farrer, Matthew J. and Sossi, Vesna 2014. Behavioral deficits and striatal DA signaling in LRRK2 p.G2019S transgenic rats: a multimodal investigation including PET neuroimaging. Journal of Parkinson{'}s disease 4 (3) , pp. 483-498. 10.3233/JPD-140344 |
Doherty, Gayle H., Beccano-Kelly, Dayne ORCID: https://orcid.org/0000-0003-3592-8354, Yan, Shi Du, Gunn-Moore, Frank J. and Harvey, Jenni 2012. Leptin prevents hippocampal synaptic disruption and neuronal cell death induced by amyloid β. Neurobiology of Aging 34 (1) , pp. 226-237. 10.1016/j.neurobiolaging.2012.08.003 |
Beccano-Kelly, Dayne ORCID: https://orcid.org/0000-0003-3592-8354 and Harvey, Jenni 2012. Leptin: a novel therapeutic target in Alzheimer's disease? International Journal of Alzheimer’s Disease 2012 , 594137. 10.1155/2012/594137 |
Milligan, Carol J., Li, Jing, Sukumar, Piruthivi, Majeed, Yasser, Dallas, Mark L., English, Anne, Emery, Paul, Porter, Karen E., Smith, Andrew M., McFadzean, Ian, Beccano-Kelly, Dayne ORCID: https://orcid.org/0000-0003-3592-8354, Bahnasi, Yahya, Cheong, Alex, Naylor, Jacqueline, Zeng, Fanning, Liu, Xing, Gamper, Nikita, Jiang, Lin-Hua, Pearson, Hugh A., Peers, Chris, Robertson, Brian and Beech, David J. 2009. Robotic multiwell planar patch-clamp for native and primary mammalian cells. Nature Protocols 4 , pp. 244-255. 10.1038/nprot.2008.230 |
Josephs, Keith A., Katsuse, Omi, Beccano-Kelly, Dayne A. ORCID: https://orcid.org/0000-0003-3592-8354, Lin, Wen-Lang, Uitti, Ryan J., Fujino, Yasuhiro, Boeve, Bradley F., Hutton, Michael L., Baker, Matthew C. and Dickson, Dennis W. 2006. Atypical progressive supranuclear palsy with corticospinal tract degeneration. Journal of Neuropathology and Experimental Neurology 65 (4) , pp. 396-405. 10.1097/01.jnen.0000218446.38158.61 |