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Number of items: 27.

Ng, Bryan, Vowles, Jane, Bertherat, Féodora, Abey, Ajantha, Kilfeather, Peter, Beccano-Kelly, Dayne ORCID: https://orcid.org/0000-0003-3592-8354, Stefana, M. Irina, O'Brien, Darragh P., Bengoa-Vergniory, Nora, Carling, Phillippa J., Todd, John A., Caffrey, Tara M., Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928, Cowley, Sally A. and Wade-Martins, Richard 2024. Tau depletion in human neurons mitigates Aβ-driven toxicity. Molecular Psychiatry 29 , pp. 2009-2020. 10.1038/s41380-024-02463-2
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Brimblecombe, Katherine R., Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928, Bataille, Carole J. R., Roberts, Bradley M., Gracie, Caitlin, O'Connor, Bethan, te Water Naude, Rebecca, Karthik, Gayathri, Russell, Angela J., Wade-Martins, Richard and Cragg, Stephanie J. 2024. Inhibition of striatal dopamine release by the L-type calcium channel inhibitor isradipine co-varies with risk factors for Parkinson's. European Journal of Neuroscience 59 (6) , pp. 1242-1259. 10.1111/ejn.16180
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Kilfeather, Peter, Khoo, Jia Hui, Wagner, Katherina, Liang, Han, Caiazza, Maria Claudia, An, Yanru, Zhang, Xingju, Chen, Xiaoyan, Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928, Shang, Zhouchun and Wade-Martins, Richard 2024. Single-cell spatial transcriptomic and translatomic profiling of dopaminergic neurons in health, aging, and disease. Cell Reports 43 (3) , 113784. 10.1016/j.celrep.2024.113784
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Maninger, Johanna-Katharina, Nowak, Karolina, Goberdhan, Srilakshmi, O'Donoghue, Rachel and Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928 2024. Cell type-specific functions of Alzheimer's disease endocytic risk genes. Philosophical Transactions of the Royal Society B: Biological Sciences 379 (1899) , 20220378. 10.1098/rstb.2022.0378
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Williamson, Matthew G, Madureira, Marta, McGuinness, William, Heon-Roberts, Rachel, Mock, Elliot D, Naidoo, Kalina, Cramb, Kaitlyn M L, Caiazza, Maria-Claudia, Malpartida, Ana B, Lavelle, Martha, Savory, Katrina, Humble, Stewart W, Patterson, Ryan, Davis, John B, Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928, Ryan, Brent J and Wade-Martins, Richard 2023. Mitochondrial dysfunction and mitophagy defects in LRRK2-R1441C Parkinson's disease models. Human Molecular Genetics 32 (18) , pp. 2808-2821. 10.1093/hmg/ddad102
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Maguire, Emily, Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928, Shaw, Bethany, O’Donoghue, Rachel, Stöberl, Nina and Hall-Roberts, Hazel 2022. Assaying microglia functions in vitro. Cells 11 (21) , 3414. 10.3390/cells11213414
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Ninkina, Natalia ORCID: https://orcid.org/0000-0001-8570-5648, Millership, Steven J., Peters, Owen M. ORCID: https://orcid.org/0000-0002-6824-0663, Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928, Chaprov, Kirill, Kopylov, Arthur T., Montoya, Alex, Kramer, Holger, Withers, Dominic J. and Buchman, Vladimir L. ORCID: https://orcid.org/0000-0002-7631-8352 2021. β-synuclein potentiates synaptic vesicle dopamine uptake and rescues dopaminergic neurons from MPTP-induced death in the absence of other synucleins. Journal of Biological Chemistry 297 (6) , 101375. 10.1016/j.jbc.2021.101375
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Threlfell, Sarah, Mohammadi, Amir Saeid, Ryan, Brent J., Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928, Platt, Nicola J., Anand, Rishi, Serres, Florence, Sharp, Trevor, Bengoa-Vergniory, Nora, Wade-Martins, Richard, Ewing, Andrew, Cragg, Stephanie J. and Brimblecombe, Katherine R. 2021. Striatal dopamine transporter function is facilitated by converging biology of α-synuclein and cholesterol. Frontiers in Cellular Neuroscience 15 , 658244. 10.3389/fncel.2021.658244
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Roberts, Bradley M., Doig, Natalie M., Brimblecombe, Katherine R., Lopes, Emanuel F., Siddorn, Ruth E., Threlfell, Sarah, Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928, Bengoa-Vergniory, Nora, Pasternack, Nicholas, Wade-Martins, Richard, Magill, Peter J. and Cragg, Stephanie J. 2020. GABA uptake transporters support dopamine release in dorsal striatum with maladaptive downregulation in a parkinsonism model. Nature Communications 11 (1) , 4958. 10.1038/s41467-020-18247-5
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Bengoa-Vergniory, Nora, Faggiani, Emilie, Ramos-Gonzalez, Paula, Kirkiz, Ecem, Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928, Brown, Liam V., Siddique, Ibrar, Li, Zizheng, Vingill, Siv, Cioroch, Milena, Cavaliere, Fabio, Threlfell, Sarah, Roberts, Bradley, Schrader, Thomas, Klärner, Frank-Gerrit, Cragg, Stephanie, Dehay, Benjamin, Bitan, Gal, Matute, Carlos, Bezard, Erwan and Wade-Martins, Richard 2020. CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease. Nature Communications 11 (1) , 4885. 10.1038/s41467-020-18689-x
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Madureira, Marta, Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928 and Wade-Martins, Richard 2020. LRRK2: Autophagy and Lysosomal Activity. Frontiers in Neuroscience 14 , 498. 10.3389/fnins.2020.00498
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Simanaviciute, Ugne, Ahmed, Jewel, Brown, Richard E, Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928, Farr, Tracy D., Fertan, Emre, Gambles, Nikki, Garland, Huw, Morton, A. Jennifer, Staiger, Jochen F., Skillings, Elizabeth A., Trueman, Rebecca C., Wade-Martins, Richard, Wood, Nigel I., Wong, Aimee A. and Grant, Robyn A. 2020. Recommendations for measuring whisker movements and locomotion in mice with sensory, motor and cognitive deficits. Journal of Neuroscience Methods 331 , 108532. 10.1016/j.jneumeth.2019.108532

Booth, Heather D.E., Wessely, Frank, Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928, Rinaldi, Federica, Vowles, Jane, Browne, Cathy, Evetts, Samuel G., Hu, Michele T., Cowley, Sally A., Webber, Caleb ORCID: https://orcid.org/0000-0001-8063-7674 and Wade-Martins, Richard 2019. RNA sequencing reveals MMP2 and TGFB1 downregulation in LRRK2 G2019S Parkinson's iPSC-derived astrocytes. Neurobiology of Disease 129 , pp. 56-66. 10.1016/j.nbd.2019.05.006
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Wallings, Rebecca, Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928 and Wade-Martins, Richard 2019. LRRK2 interacts with the vacuolar-type H+-ATPase pump a1 subunit to regulate lysosomal function. Human Molecular Genetics 28 (16) , 2696–2710. 10.1093/hmg/ddz088
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Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928, Booth, Heather, Martin, Jeffrey G., Gao, Benbo, Li, Kejie, Doig, Natalie, Vowles, Jane, Browne, Cathy, Klinger, Laura, Juhasz, Peter, Klein, Christine, Cowley, Sally A., Bolam, Paul, Hirst, Warren and Wade-Martins, Richard 2019. An integrated transcriptomics and proteomics analysis reveals functional endocytic dysregulation caused by mutations in LRRK2. Neurobiology of Disease 127 , pp. 512-526. 10.1016/j.nbd.2019.04.005
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Vingill, Siv, Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928 and Wade-Martins, Richard 2018. Are rodent models of Parkinson's disease behaving as they should? Behavioural Brain Research 352 , pp. 133-141. 10.1016/j.bbr.2017.10.021

Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928, Peters, Owen ORCID: https://orcid.org/0000-0002-6824-0663, Millership, Steven, Ninkina, Natalia ORCID: https://orcid.org/0000-0001-8570-5648 and Buchman, Vladimir L. ORCID: https://orcid.org/0000-0002-7631-8352 2016. Combinational losses of synucleins reveal their differential requirements for compensating age-dependent alterations in motor behavior and dopamine metabolism. Neurobiology of Aging 46 , pp. 107-112. 10.1016/j.neurobiolaging.2016.06.020
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Telezhkin, Vsevolod, Schnell, Christian, Yarova, Polina L., Yung, Sun, Sanders, Philip, Cope, Emma, Hughes, Alis, Thompson, Belinda A, Geater, Charlene, Hancock, Jane M., Joy, Shona, Badder, Luned, Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928, Comella, Andrea, Straccia, Marco, Bombau, Georgina, Brown, Jon T, Canals, Josep M., Randall, Andrew D., Allen, Nicholas Denby ORCID: https://orcid.org/0000-0003-4009-186X and Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X 2016. Forced cell-cycle exit and modulation of GABAA, CREB and GSK3β signaling promote functional maturation of induced pluripotent stem cell-derived neurons. American Journal of Physiology - Cell Physiology , ajpcell.00166.2015. 10.1152/ajpcell.00166.2015

Sloan, Max, Alegre-Abarrategui, Javier, Potgieter, Dawid, Kaufmann, Anna-Kristin, Exley, Richard, Deltheil, Thierry, Threlfell, Sarah, Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928, Brimblecombe, Katherine, Wallings, Rebecca, Cioroch, Milena, Bannerman, David M., Bolam, J. Paul, Magill, Peter J., Cragg, Stephanie J., Dodson, Paul D. and Wade-Martins, Richard 2016. LRRK2 BAC transgenic rats develop progressive, L-DOPA-responsive motor impairment, and deficits in dopamine circuit function. Human Molecular Genetics 25 (5) , pp. 951-963. 10.1093/hmg/ddv628
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Ninkina, Natalia ORCID: https://orcid.org/0000-0001-8570-5648, Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928, Ustyugov, Alexey A., Tarasova, Tatiana, Shelkovnikova, Tatyana ORCID: https://orcid.org/0000-0003-1367-5309 and Buchman, Vladimir L. ORCID: https://orcid.org/0000-0002-7631-8352 2015. A novel resource for studying function and dysfunction of α-synuclein: mouse lines for modulation of endogenous Snca gene expression. Scientific Reports 5 , 16615. 10.1038/srep16615
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Cooper-Knock, Johnathan, Higginbottom, Adrian, Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928, Bayatti, Nadhim, Bury, Joanna J., Kirby, Janine, Ninkina, Natalia ORCID: https://orcid.org/0000-0001-8570-5648, Buchman, Vladimir L. ORCID: https://orcid.org/0000-0002-7631-8352 and Shaw, Pamela J. 2013. C9ORF72 transcription in a frontotemporal dementia case with two expanded alleles. Neurology 81 (19) , pp. 1719-1721. 10.1212/01.wnl.0000435295.41974.2e

Shelkovnikova, Tatyana ORCID: https://orcid.org/0000-0003-1367-5309, Robinson, Hannah, Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928 and Buchman, Vladimir L. ORCID: https://orcid.org/0000-0002-7631-8352 2013. Recruitment into stress granules prevents irreversible aggregation of FUS protein mislocalized to the cytoplasm. Cell Cycle 12 (19) , pp. 3194-3202. 10.4161/cc.26241

Shelkovnikova, Tatyana ORCID: https://orcid.org/0000-0003-1367-5309, Peters, Owen Morgan ORCID: https://orcid.org/0000-0002-6824-0663, Deykin, Alexey V., Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928, Robinson, Hannah, Ustyugov, Aleksey ORCID: https://orcid.org/0000-0003-1977-4797, Bachurin, Sergey O., Ermolkevich, Tatyana G., Goldman, Igor L., Sadchikova, Elena R., Kovrazhkina, Elena A., Skvortsova, Veronica I., Ling, Shuo-Chien, Da Cruz, Sandrine, Parone, Philippe A., Buchman, Vladimir L. ORCID: https://orcid.org/0000-0002-7631-8352 and Ninkina, Natalia ORCID: https://orcid.org/0000-0001-8570-5648 2013. Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic mice. Journal of Biological Chemistry 288 (35) , pp. 25266-25274. 10.1074/jbc.M113.492017

Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928 2013. Synucleins in the midbrain dopaminergic system: the role in health and disease. PhD Thesis, Cardiff University.
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Peters, Owen Morgan ORCID: https://orcid.org/0000-0002-6824-0663, Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928, Sokolov, V. B., Aksinenko, A. Y., Kukharsky, M. S., Bachurin, S. O., Ninkina, Natalia ORCID: https://orcid.org/0000-0001-8570-5648 and Buchman, Vladimir L. ORCID: https://orcid.org/0000-0002-7631-8352 2013. Chronic administration of dimebon ameliorates pathology in Tau P301S transgenic mice. Journal of Alzheimer's Disease 33 (4) , pp. 1041-1049. 10.3233/JAD-2012-121732

Ninkina, Natalia ORCID: https://orcid.org/0000-0001-8570-5648, Peters, Owen Morgan ORCID: https://orcid.org/0000-0002-6824-0663, Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928, Lytkina, Olga, Sharfeddin, Essam and Buchman, Vladimir L. ORCID: https://orcid.org/0000-0002-7631-8352 2012. Contrasting effects of α-Synuclein and γ-Synuclein on the phenotype of cysteine string protein α (CSPα) null mutant mice suggest distinct function of these proteins in neuronal synapses. Journal of Biological Chemistry 287 (53) , pp. 44471-44477. 10.1074/jbc.M112.422402

Anwar, Shabana, Peters, Owen Morgan ORCID: https://orcid.org/0000-0002-6824-0663, Millership, Steven, Ninkina, Natalia ORCID: https://orcid.org/0000-0001-8570-5648, Doig, N., Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928, Threlfell, Sarah, Kooner, Gurdeep, Deacon, R., Bannerman, D., Bolam, J., Chandra, S., Cragg, Sarah, Wade- Martins, Richard and Buchman, Vladimir L. ORCID: https://orcid.org/0000-0002-7631-8352 2011. Functional alterations to the nigrostriatal system in mice lacking all three members of the synuclein family. Journal of Neuroscience 31 (20) , pp. 7264-7274. 10.1523/JNEUROSCI.6194-10.2011
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This list was generated on Tue Oct 28 11:34:31 2025 GMT.


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