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Number of items: 21.

Ninkina, Natalia, Millership, Steven J., Peters, Owen M., Connor-Robson, Natalie, Chaprov, Kirill, Kopylov, Arthur T., Montoya, Alex, Kramer, Holger, Withers, Dominic J. and Buchman, Vladimir L. 2021. β-synuclein potentiates synaptic vesicle dopamine uptake and rescues dopaminergic neurons from MPTP-induced death in the absence of other synucleins. Journal of Biological Chemistry 297 (6) , 101375. 10.1016/j.jbc.2021.101375

Threlfell, Sarah, Mohammadi, Amir Saeid, Ryan, Brent J., Connor-Robson, Natalie, Platt, Nicola J., Anand, Rishi, Serres, Florence, Sharp, Trevor, Bengoa-Vergniory, Nora, Wade-Martins, Richard, Ewing, Andrew, Cragg, Stephanie J. and Brimblecombe, Katherine R. 2021. Striatal dopamine transporter function is facilitated by converging biology of α-synuclein and cholesterol. Frontiers in Cellular Neuroscience 15 , 658244. 10.3389/fncel.2021.658244

Roberts, Bradley M., Doig, Natalie M., Brimblecombe, Katherine R., Lopes, Emanuel F., Siddorn, Ruth E., Threlfell, Sarah, Connor-Robson, Natalie, Bengoa-Vergniory, Nora, Pasternack, Nicholas, Wade-Martins, Richard, Magill, Peter J. and Cragg, Stephanie J. 2020. GABA uptake transporters support dopamine release in dorsal striatum with maladaptive downregulation in a parkinsonism model. Nature Communications 11 (1) , 4958. 10.1038/s41467-020-18247-5

Bengoa-Vergniory, Nora, Faggiani, Emilie, Ramos-Gonzalez, Paula, Kirkiz, Ecem, Connor-Robson, Natalie, Brown, Liam V., Siddique, Ibrar, Li, Zizheng, Vingill, Siv, Cioroch, Milena, Cavaliere, Fabio, Threlfell, Sarah, Roberts, Bradley, Schrader, Thomas, Klärner, Frank-Gerrit, Cragg, Stephanie, Dehay, Benjamin, Bitan, Gal, Matute, Carlos, Bezard, Erwan and Wade-Martins, Richard 2020. CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease. Nature Communications 11 (1) , 4885. 10.1038/s41467-020-18689-x

Madureira, Marta, Connor-Robson, Natalie and Wade-Martins, Richard 2020. LRRK2: Autophagy and Lysosomal Activity. Frontiers in Neuroscience 14 , 498. 10.3389/fnins.2020.00498

Simanaviciute, Ugne, Ahmed, Jewel, Brown, Richard E, Connor-Robson, Natalie, Farr, Tracy D., Fertan, Emre, Gambles, Nikki, Garland, Huw, Morton, A. Jennifer, Staiger, Jochen F., Skillings, Elizabeth A., Trueman, Rebecca C., Wade-Martins, Richard, Wood, Nigel I., Wong, Aimee A. and Grant, Robyn A. 2020. Recommendations for measuring whisker movements and locomotion in mice with sensory, motor and cognitive deficits. Journal of Neuroscience Methods 331 , 108532. 10.1016/j.jneumeth.2019.108532

Booth, Heather D.E., Wessely, Frank, Connor-Robson, Natalie, Rinaldi, Federica, Vowles, Jane, Browne, Cathy, Evetts, Samuel G., Hu, Michele T., Cowley, Sally A., Webber, Caleb and Wade-Martins, Richard 2019. RNA sequencing reveals MMP2 and TGFB1 downregulation in LRRK2 G2019S Parkinson's iPSC-derived astrocytes. Neurobiology of Disease 129 , pp. 56-66. 10.1016/j.nbd.2019.05.006

Wallings, Rebecca, Connor-Robson, Natalie and Wade-Martins, Richard 2019. LRRK2 interacts with the vacuolar-type H+-ATPase pump a1 subunit to regulate lysosomal function. Human Molecular Genetics 28 (16) , 2696–2710. 10.1093/hmg/ddz088

Connor-Robson, Natalie, Booth, Heather, Martin, Jeffrey G., Gao, Benbo, Li, Kejie, Doig, Natalie, Vowles, Jane, Browne, Cathy, Klinger, Laura, Juhasz, Peter, Klein, Christine, Cowley, Sally A., Bolam, Paul, Hirst, Warren and Wade-Martins, Richard 2019. An integrated transcriptomics and proteomics analysis reveals functional endocytic dysregulation caused by mutations in LRRK2. Neurobiology of Disease 127 , pp. 512-526. 10.1016/j.nbd.2019.04.005

Vingill, Siv, Connor-Robson, Natalie and Wade-Martins, Richard 2018. Are rodent models of Parkinson's disease behaving as they should? Behavioural Brain Research 352 , pp. 133-141. 10.1016/j.bbr.2017.10.021

Connor-Robson, Natalie, Peters, Owen, Millership, Steven, Ninkina, Natalia and Buchman, Vladimir L. 2016. Combinational losses of synucleins reveal their differential requirements for compensating age-dependent alterations in motor behavior and dopamine metabolism. Neurobiology of Aging 46 , pp. 107-112. 10.1016/j.neurobiolaging.2016.06.020

Telezhkin, Vsevolod, Schnell, Christian, Yarova, Polina L., Yung, Sun, Sanders, Philip, Cope, Emma, Hughes, Alis, Thompson, Belinda A, Geater, Charlene, Hancock, Jane M., Joy, Shona, Badder, Luned, Connor-Robson, Natalie, Comella, Andrea, Straccia, Marco, Bombau, Georgina, Brown, Jon T, Canals, Josep M., Randall, Andrew D., Allen, Nicholas Denby and Kemp, Paul J. 2016. Forced cell-cycle exit and modulation of GABAA, CREB and GSK3β signaling promote functional maturation of induced pluripotent stem cell-derived neurons. American Journal of Physiology - Cell Physiology , ajpcell.00166.2015. 10.1152/ajpcell.00166.2015

Sloan, Max, Alegre-Abarrategui, Javier, Potgieter, Dawid, Kaufmann, Anna-Kristin, Exley, Richard, Deltheil, Thierry, Threlfell, Sarah, Connor-Robson, Natalie, Brimblecombe, Katherine, Wallings, Rebecca, Cioroch, Milena, Bannerman, David M., Bolam, J. Paul, Magill, Peter J., Cragg, Stephanie J., Dodson, Paul D. and Wade-Martins, Richard 2016. LRRK2 BAC transgenic rats develop progressive, L-DOPA-responsive motor impairment, and deficits in dopamine circuit function. Human Molecular Genetics 25 (5) , pp. 951-963. 10.1093/hmg/ddv628

Ninkina, Natalia, Connor-Robson, Natalie, Ustyugov, Alexey A., Tarasova, Tatiana, Shelkovnikova, Tatyana and Buchman, Vladimir L. 2015. A novel resource for studying function and dysfunction of α-synuclein: mouse lines for modulation of endogenous Snca gene expression. Scientific Reports 5 , 16615. 10.1038/srep16615

Cooper-Knock, Johnathan, Higginbottom, Adrian, Connor-Robson, Natalie, Bayatti, Nadhim, Bury, Joanna J., Kirby, Janine, Ninkina, Natalia, Buchman, Vladimir L. and Shaw, Pamela J. 2013. C9ORF72 transcription in a frontotemporal dementia case with two expanded alleles. Neurology 81 (19) , pp. 1719-1721. 10.1212/01.wnl.0000435295.41974.2e

Shelkovnikova, Tatyana, Robinson, Hannah, Connor-Robson, Natalie and Buchman, Vladimir L. 2013. Recruitment into stress granules prevents irreversible aggregation of FUS protein mislocalized to the cytoplasm. Cell Cycle 12 (19) , pp. 3194-3202. 10.4161/cc.26241

Shelkovnikova, Tatyana, Peters, Owen Morgan, Deykin, Alexey V., Connor-Robson, Natalie, Robinson, Hannah, Ustyugov, Aleksey, Bachurin, Sergey O., Ermolkevich, Tatyana G., Goldman, Igor L., Sadchikova, Elena R., Kovrazhkina, Elena A., Skvortsova, Veronica I., Ling, Shuo-Chien, Da Cruz, Sandrine, Parone, Philippe A., Buchman, Vladimir L. and Ninkina, Natalia 2013. Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic mice. Journal of Biological Chemistry 288 (35) , pp. 25266-25274. 10.1074/jbc.M113.492017

Peters, Owen Morgan, Connor-Robson, Natalie, Sokolov, V. B., Aksinenko, A. Y., Kukharsky, M. S., Bachurin, S. O., Ninkina, Natalia and Buchman, Vladimir L. 2013. Chronic administration of dimebon ameliorates pathology in Tau P301S transgenic mice. Journal of Alzheimer's Disease 33 (4) , pp. 1041-1049. 10.3233/JAD-2012-121732

Connor-Robson, Natalie 2013. Synucleins in the midbrain dopaminergic system: the role in health and disease. PhD Thesis, Cardiff University.
Item availability restricted.

Ninkina, Natalia, Peters, Owen Morgan, Connor-Robson, Natalie, Lytkina, Olga, Sharfeddin, Essam and Buchman, Vladimir L. 2012. Contrasting effects of α-Synuclein and γ-Synuclein on the phenotype of cysteine string protein α (CSPα) null mutant mice suggest distinct function of these proteins in neuronal synapses. Journal of Biological Chemistry 287 (53) , pp. 44471-44477. 10.1074/jbc.M112.422402

Anwar, Shabana, Peters, Owen Morgan, Millership, Steven, Ninkina, Natalia, Doig, N., Connor-Robson, Natalie, Threlfell, Sarah, Kooner, Gurdeep, Deacon, R., Bannerman, D., Bolam, J., Chandra, S., Cragg, Sarah, Wade- Martins, Richard and Buchman, Vladimir L. 2011. Functional alterations to the nigrostriatal system in mice lacking all three members of the synuclein family. Journal of Neuroscience 31 (20) , pp. 7264-7274. 10.1523/JNEUROSCI.6194-10.2011

This list was generated on Sun Aug 14 03:25:16 2022 BST.