Chakroborty, Anand, Pritchard, Deiniol R., Bouillon, Marc E., Cervi, Anna, Kraehenbuehl, Rolf, Wild, Charlotte, Fenn, Caroline, Holdsworth, Peter, Capner, Colin, Padalino, Gilda, Forde-Thomas, Josephine E., Payne, Joseph, Smith, Brendan G., Fisher, Maggie, Lahmann, Martina, Baird, Mark S. and Hoffmann, Karl F.
2023.
Modified hederagenin derivatives demonstrate ex vivo anthelmintic activity against fasciola hepatica.
Pharmaceutics
15
(7)
, 1869.
10.3390/pharmaceutics15071869
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Padalino, Gilda, Coghlan, Avril, Pagliuca, Giampaolo, Forde-Thomas, Josephine E., Berriman, Matthew and Hoffmann, Karl F.
2023.
Using ChEMBL to complement schistosome drug discovery.
Pharmaceutics
15
(5)
, 1359.
10.3390/pharmaceutics15051359
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Caldwell, Nicola, Afshar, Rana, Baragaña, Beatriz, Bustinduy, Amaya L., Caffrey, Conor R., Collins, James J., Fusco, Daniela, Garba, Amadou, Gardner, Mark, Gomes, Mireille, Hoffmann, Karl F., Hsieh, Michael, Lo, Nathan C., McNamara, Case W., Nono, Justin Komguep, Padalino, Gilda, Read, Kevin D., Roestenberg, Meta, Spangenberg, Thomas, Specht, Sabine and Gilbert, Ian H.
2023.
Perspective on schistosomiasis drug discovery: highlights from a schistosomiasis drug discovery workshop at Wellcome Collection, London, September 2022.
ACS Infectious Diseases
9
(5)
, pp. 1046-1055.
10.1021/acsinfecdis.3c00081
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Padalino, Gilda, Celatka, Cassandra A., Rienhoff Jr., Hugh Y., Kalin, Jay H., Cole, Philip A., Lassalle, Damien, Forde-Thomas, Josephine, Chalmers, Iain W., Brancale, Andrea ![]() ![]() |
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Giancotti, Gilda, Nannetti, Giulio ![]() ![]() ![]() ![]() ![]() |
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Chakroborty, Anand, Pritchard, Deiniol, Bouillon, Marc E., Cervi, Anna, Cookson, Alan, Wild, Charlotte, Fenn, Caroline, Payne, Joseph, Holdsworth, Peter, Capner, Colin, O'Neill, Jenna, Padalino, Gilda, Forde-Thomas, Josephine, Gupta, Sandeep, Smith, Brendan G., Fisher, Maggie, Lahmann, Martina, Baird, Mark S. and Hoffmann, Karl F.
2022.
Flukicidal effects of abietane diterpenoid derived analogues against the food borne pathogen Fasciola hepatica.
Veterinary Parasitology
309
, 109766.
10.1016/j.vetpar.2022.109766
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Coghlan, Avril, Padalino, Gilda, O'Boyle, Noel M., Hoffmann, Karl F. and Berriman, Matthew
2022.
Identification of anti-schistosomal, anthelmintic and anti-parasitic compounds curated and text-mined from the scientific literature.
Wellcome Open Research
7
, 193.
10.12688/wellcomeopenres.17987.1
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Hsieh, Michael H., Hulme, Benjamin J., Geyer, Kathrin K., Forde-Thomas, Josephine E., Padalino, Gilda, Phillips, Dylan W., Ittiprasert, Wannaporn, Karinshak, Shannon E., Mann, Victoria H., Chalmers, Iain W., Brindley, Paul J., Hokke, Cornelis H. and Hoffmann, Karl F.
2022.
Schistosoma mansoni α-N-acetylgalactosaminidase (SmNAGAL) regulates coordinated parasite movement and egg production.
PLoS Pathogens
18
(1)
, e1009828.
10.1371/journal.ppat.1009828
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Padalino, Gilda, El-Sakkary, Nelly, Liu, Lawrence J., Liu, Chenxi, Harte, Danielle S.G., Barnes, Rachel E., Sayers, Edward ![]() ![]() ![]() ![]() |
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Dalton, John Pius, Gasan, Thomas A., Kuipers, Marije E., Roberts, Grisial H., Padalino, Gilda, Forde-Thomas, Josephine E., Wilson, Shona, Wawrzyniak, Jakub, Tukahebwa, Edridah M., Hoffmann, Karl F. and Chalmers, Iain W.
2021.
Schistosoma mansoni Larval Extracellular Vesicle protein 1 (SmLEV1) is an immunogenic antigen found in EVs released from pre-acetabular glands of invading cercariae.
PLoS Neglected Tropical Diseases
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, e0009981.
10.1371/journal.pntd.0009981
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Padalino, Gilda, Chalmers, Iain W., Brancale, Andrea ![]() ![]() |
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Wang, Jipeng, Paz, Carlos, Padalino, Gilda, Coghlan, Avril, Lu, Zhigang, Gradinaru, Irina, Collins, Julie N. R., Berriman, Matthew, Hoffmann, Karl F. and Collins, James J. 2020. Large-scale RNAi screening uncovers therapeutic targets in the parasite Schistosoma mansoni. Science 369 (6511) , pp. 1649-1653. 10.1126/science.abb7699 |
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Padalino, Gilda, Whatley, Kezia C. L., Whiteland, Helen, Geyer, Kathrin K., Hulme, Benjamin J., Chalmers, Iain W., Forde-Thomas, Josephine, Ferla, Salvatore ![]() ![]() ![]() |
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Padalino, Gilda, Ferla, Salvatore ![]() ![]() |
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Hsieh, Michael H., Roquis, David, Taudt, Aaron, Geyer, Kathrin K., Padalino, Gilda, Hoffmann, Karl F., Holroyd, Nancy, Berriman, Matt, Aliaga, Benoît, Chaparro, Cristian, Grunau, Christoph and Augusto, Ronaldo de Carvalho 2018. Histone methylation changes are required for life cycle progression in the human parasite Schistosoma mansoni. PLoS Pathogens 14 (5) 10.1371/journal.ppat.1007066 |
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